{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:29:47Z","timestamp":1787243387551,"version":"build-2736575974"},"reference-count":46,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,9,30]],"date-time":"2014-09-30T00:00:00Z","timestamp":1412035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","archives-pmr.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Physical Medicine and Rehabilitation"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.apmr.2014.09.012","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T21:49:01Z","timestamp":1412372941000},"page":"S104-S113","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"S","title":["Safety of Primed Repetitive Transcranial Magnetic Stimulation and Modified Constraint-Induced Movement Therapy in\u00a0a Randomized Controlled Trial in Pediatric Hemiparesis"],"prefix":"10.1016","volume":"96","author":[{"given":"Bernadette T.","family":"Gillick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda E.","family":"Krach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Feyma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonya L.","family":"Rich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelli","family":"Moberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremiah","family":"Menk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Cassidy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Kimberley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"Carey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.apmr.2014.09.012_bib1","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1111\/j.1468-1331.2009.02746.x","article-title":"Role of 1 and 3 Hz repetitive transcranial magnetic stimulation on motor function recovery after acute ischaemic stroke","volume":"16","author":"Khedr","year":"2009","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib2","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1155\/NP.2005.245","article-title":"A critical review of constraint-induced movement therapy and forced use in children with hemiplegia","volume":"12","author":"Charles","year":"2005","journal-title":"Neural Plast"},{"key":"10.1016\/j.apmr.2014.09.012_bib3","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1002\/ana.10848","article-title":"Influence of interhemispheric interactions on motor function in chronic stroke","volume":"55","author":"Murase","year":"2004","journal-title":"Ann Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib4","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1007\/s00415-011-6364-7","article-title":"Transcranial magnetic stimulation in mild to severe hemiparesis early after stroke: a proof of principle and novel approach to improve motor function","volume":"259","author":"Conforto","year":"2012","journal-title":"J Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib5","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1161\/01.STR.0000231390.58967.6b","article-title":"A sham-controlled trial of a 5-day course of repetitive transcranial magnetic stimulation of the\u00a0unaffected hemisphere in stroke patients","volume":"37","author":"Fregni","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.apmr.2014.09.012_bib6","doi-asserted-by":"crossref","first-page":"10867","DOI":"10.1523\/JNEUROSCI.23-34-10867.2003","article-title":"Priming stimulation enhances the depressant effect of low-frequency repetitive transcranial magnetic stimulation","volume":"23","author":"Iyer","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.apmr.2014.09.012_bib7","doi-asserted-by":"crossref","first-page":"139","DOI":"10.2522\/ptj.20130027","article-title":"Priming the brain to capitalize on metaplasticity in stroke rehabilitation","volume":"94","author":"Cassidy","year":"2014","journal-title":"Phys Ther"},{"key":"10.1016\/j.apmr.2014.09.012_bib8","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1038\/36103","article-title":"Activity-dependent scaling of quantal amplitude in neocortical neurons","volume":"391","author":"Turrigiano","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.apmr.2014.09.012_bib9","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1523\/JNEUROSCI.02-01-00032.1982","article-title":"Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex","volume":"2","author":"Bienenstock","year":"1982","journal-title":"J Neurosci"},{"key":"10.1016\/j.apmr.2014.09.012_bib10","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1006\/nlme.2000.4004","article-title":"Motor learning-dependent synaptogenesis is localized to functionally reorganized motor cortex","volume":"77","author":"Kleim","year":"2002","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.apmr.2014.09.012_bib11","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1001\/jama.296.17.2095","article-title":"Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial","volume":"296","author":"Wolf","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.apmr.2014.09.012_bib12","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s004150170207","article-title":"Motor cortex plasticity during forced-use therapy in stroke patients: a preliminary study","volume":"248","author":"Liepert","year":"2001","journal-title":"J Neurol"},{"issue":"2","key":"10.1016\/j.apmr.2014.09.012_bib13","first-page":"CD004149","article-title":"Constraint-induced movement therapy in the treatment of the upper limb in children with hemiplegic cerebral palsy","author":"Hoare","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.apmr.2014.09.012_bib14","first-page":"424","article-title":"Transcranial magnetic stimulation and its applications in children","volume":"25","author":"Lin","year":"2002","journal-title":"Chang Gung Med J"},{"key":"10.1016\/j.apmr.2014.09.012_bib15","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1177\/0883073807307972","article-title":"Transcranial magnetic stimulation in child neurology: current and future directions","volume":"23","author":"Frye","year":"2008","journal-title":"J Child Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib16","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1016\/j.clinph.2010.04.021","article-title":"Cortical excitability and interhemispheric inhibition after subcortical pediatric stroke: plastic organization and effects of rTMS","volume":"121","author":"Kirton","year":"2010","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2014.09.012_bib17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S1474-4422(08)70096-6","article-title":"Contralesional repetitive transcranial magnetic stimulation for chronic hemiparesis in subcortical paediatric stroke: a randomised trial","volume":"7","author":"Kirton","year":"2008","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib18","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/1545968307305458","article-title":"Safety of 6-Hz primed low-frequency rTMS in stroke","volume":"22","author":"Carey","year":"2008","journal-title":"Neurorehabil Neural Repair"},{"key":"10.1016\/j.apmr.2014.09.012_bib19","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3233\/NRE-2011-0714","article-title":"Application of combined 6-Hz primed low-frequency rTMS and intensive occupational therapy for upper limb hemiparesis after stroke","volume":"29","author":"Kakuda","year":"2011","journal-title":"NeuroRehabilitation"},{"key":"10.1016\/j.apmr.2014.09.012_bib20","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.spen.2013.06.004","article-title":"Can noninvasive brain stimulation measure and modulate developmental plasticity to improve function in stroke-induced cerebral palsy?","volume":"20","author":"Kirton","year":"2013","journal-title":"Semin Pediatr Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib21","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s11060-013-1247-7","article-title":"Cortical hemosiderin is associated with seizures in patients with newly diagnosed malignant brain tumors","volume":"115","author":"Roelcke","year":"2013","journal-title":"J Neurooncol"},{"key":"10.1016\/j.apmr.2014.09.012_bib22","doi-asserted-by":"crossref","first-page":"288","DOI":"10.4103\/0028-3886.115070","article-title":"Extended resection of hemosiderin fringe is better for seizure outcome: a study in patients with cavernous malformation associated with refractory epilepsy","volume":"61","author":"Wang","year":"2013","journal-title":"Neurol India"},{"key":"10.1016\/j.apmr.2014.09.012_bib23","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1016\/j.clinph.2006.01.016","article-title":"Arm function after stroke: neurophysiological correlates and recovery mechanisms assessed by transcranial magnetic stimulation","volume":"117","author":"Talelli","year":"2006","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2014.09.012_bib24","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/1545968309345270","article-title":"Contribution of transcranial magnetic stimulation to the understanding of functional recovery mechanisms after stroke","volume":"24","author":"Dimyan","year":"2010","journal-title":"Neurorehabil Neural Repair"},{"key":"10.1016\/j.apmr.2014.09.012_bib25","doi-asserted-by":"crossref","first-page":"7521","DOI":"10.1523\/JNEUROSCI.6751-10.2011","article-title":"Long-term effects of repetitive transcranial magnetic stimulation on markers for neuroplasticity: differential outcomes in anesthetized and awake animals","volume":"31","author":"Gersner","year":"2011","journal-title":"J Neurosci"},{"key":"10.1016\/j.apmr.2014.09.012_bib26","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1126\/science.290.5491.533","article-title":"Learning-induced LTP in neocortex","volume":"290","author":"Rioult-Pedotti","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.apmr.2014.09.012_bib27","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1161\/01.STR.0000206463.66461.97","article-title":"A placebo-controlled trial of constraint-induced movement therapy for upper extremity after stroke","volume":"37","author":"Taub","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.apmr.2014.09.012_bib28","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.brs.2009.02.002","article-title":"Sham transcranial magnetic stimulation using electrical stimulation of the scalp","volume":"2","author":"Mennemeier","year":"2009","journal-title":"Brain Stimul"},{"key":"10.1016\/j.apmr.2014.09.012_bib29","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1177\/088307380001500508","article-title":"Neurologic outcome in survivors of childhood arterial ischemic stroke and sinovenous thrombosis","volume":"15","author":"deVeber","year":"2000","journal-title":"J Child Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib30","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1471-2474-8-50","article-title":"Association between gross motor function (GMFCS) and manual ability (MACS) in children with cerebral palsy. A population-based study of 359 children","volume":"8","author":"Carnahan","year":"2007","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.apmr.2014.09.012_bib31","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/ptj\/67.2.206","article-title":"Interrater reliability of a modified Ashworth scale of muscle spasticity","volume":"67","author":"Bohannon","year":"1987","journal-title":"Phys Ther"},{"key":"10.1016\/j.apmr.2014.09.012_bib32","first-page":"888","article-title":"Manual stretch: effect on finger movement control and force control in stroke subjects with spastic extrinsic finger flexor muscles","volume":"71","author":"Carey","year":"1990","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2014.09.012_bib33","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1111\/j.1469-8749.2002.tb00845.x","article-title":"Comparing tests of tactile sensibility: aspects relevant to testing children with spastic hemiplegia","volume":"44","author":"Krumlinde-Sundholm","year":"2002","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib34","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/0363-5023(93)90361-6","article-title":"Sensibility deficiencies in the hands of children with spastic hemiplegia","volume":"18","author":"Van Heest","year":"1993","journal-title":"J Hand Surg [Am]"},{"key":"10.1016\/j.apmr.2014.09.012_bib35","series-title":"The token test for children, manual","author":"DiSimoni","year":"1978"},{"key":"10.1016\/j.apmr.2014.09.012_bib36","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1093\/arclin\/acs072","article-title":"The value of the wechsler intelligence scale for children-fourth edition digit span as an embedded measure of effort: an investigation into children with dual diagnoses","volume":"27","author":"Loughan","year":"2012","journal-title":"Arch Clin Neuropsychol"},{"key":"10.1016\/j.apmr.2014.09.012_bib37","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1177\/088307380101601205","article-title":"Subjective reactions of children to single-pulse transcranial magnetic stimulation","volume":"16","author":"Garvey","year":"2001","journal-title":"J Child Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib38","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1161\/01.STR.0000221233.55497.51","article-title":"Repetitive transcranial magnetic stimulation-induced corticomotor excitability and associated motor skill acquisition in chronic stroke","volume":"37","author":"Kim","year":"2006","journal-title":"Stroke"},{"key":"10.1016\/j.apmr.2014.09.012_bib39","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1097\/PEC.0b013e3181d6db37","article-title":"The pediatric assessment triangle: a novel approach for the rapid evaluation of children","volume":"26","author":"Dieckmann","year":"2010","journal-title":"Pediatric Emerg Care"},{"key":"10.1016\/j.apmr.2014.09.012_bib40","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.3109\/02699052.2010.523040","article-title":"Low-frequency rTMS combined with intensive occupational therapy for upper limb hemiparesis after brain tumour resection","volume":"24","author":"Kakuda","year":"2010","journal-title":"Brain Inj"},{"key":"10.1016\/j.apmr.2014.09.012_bib41","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.pediatrneurol.2008.06.004","article-title":"Neurocardiogenic syncope complicating pediatric transcranial magnetic stimulation","volume":"39","author":"Kirton","year":"2008","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.apmr.2014.09.012_bib42","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.clinph.2005.10.014","article-title":"Safety of rTMS to non-motor cortical areas in healthy participants and patients","volume":"117","author":"Machii","year":"2006","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2014.09.012_bib43","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.clinph.2012.07.024","article-title":"Comparative incidence rates of mild adverse effects to transcranial magnetic stimulation","volume":"124","author":"Maizey","year":"2013","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2014.09.012_bib44","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1016\/S1388-2457(02)00187-6","article-title":"Nausea as a complication of low-frequency repetitive transcranial magnetic stimulation of the posterior fossa","volume":"113","author":"Satow","year":"2002","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.apmr.2014.09.012_bib45","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1542\/peds.113.2.305","article-title":"Efficacy of constraint-induced movement therapy for children with cerebral palsy with asymmetric motor impairment","volume":"113","author":"Taub","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.apmr.2014.09.012_bib46","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.clinph.2007.11.048","article-title":"Transcranial magnetic stimulation in children","volume":"119","author":"Garvey","year":"2008","journal-title":"Clin Neurophysiol"}],"container-title":["Archives of Physical Medicine and Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999314011186?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999314011186?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T06:58:34Z","timestamp":1598338714000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003999314011186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S0003999314011186"],"URL":"https:\/\/doi.org\/10.1016\/j.apmr.2014.09.012","relation":{},"ISSN":["0003-9993"],"issn-type":[{"value":"0003-9993","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Safety of Primed Repetitive Transcranial Magnetic Stimulation and Modified Constraint-Induced Movement Therapy in\u00a0a Randomized Controlled Trial in Pediatric Hemiparesis","name":"articletitle","label":"Article Title"},{"value":"Archives of Physical Medicine and Rehabilitation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.apmr.2014.09.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"name":"copyright","label":"Copyright"}]}}