{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T10:21:22Z","timestamp":1780395682604,"version":"3.54.1"},"reference-count":48,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100006380","name":"Rehabilitation Research and Development Service","doi-asserted-by":"publisher","award":["#B9212-C"],"award-info":[{"award-number":["#B9212-C"]}],"id":[{"id":"10.13039\/100006380","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000738","name":"US Department of Veterans Affairs","doi-asserted-by":"publisher","award":["IK2RX003847-01A2"],"award-info":[{"award-number":["IK2RX003847-01A2"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["archives-pmr.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Physical Medicine and Rehabilitation"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.apmr.2026.01.013","type":"journal-article","created":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T23:15:05Z","timestamp":1769296505000},"page":"1371-1379","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Albuterol Repetabs on Pulmonary Function in Individuals With Chronic Spinal Cord Injury"],"prefix":"10.1016","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0228-9843","authenticated-orcid":false,"given":"Gino S.","family":"Panza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael F.","family":"La Fountaine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommy W.","family":"Sutor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Cirnigliaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven C.","family":"Kirshblum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Hobson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill M.","family":"Wecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Radulovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D.","family":"Delgado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Bauman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory J.","family":"Schilero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.apmr.2026.01.013_bib0001","series-title":"Traumatic spinal cord injury facts and figures at a glance","year":"2024"},{"key":"10.1016\/j.apmr.2026.01.013_bib0002","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.ccm.2018.02.002","article-title":"Traumatic spinal cord injury: pulmonary physiologic principles and management","volume":"39","author":"Schilero","year":"2018","journal-title":"Clin Chest Med"},{"key":"10.1016\/j.apmr.2026.01.013_bib0003","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.apmr.2021.08.015","article-title":"Is sleep disordered breathing confounding rehabilitation outcomes in spinal cord injury research?","volume":"103","author":"Panza","year":"2022","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2026.01.013_bib0004","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.apmr.2023.08.006","article-title":"The clinical relevance of autonomic dysfunction, cerebral hemodynamics, and sleep interactions in individuals living with SCI","volume":"105","author":"Ji","year":"2024","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2026.01.013_bib0005","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.apmr.2018.08.179","article-title":"The burden of traumatic spinal cord injury in the United States: disability-adjusted life years","volume":"100","author":"Hall","year":"2019","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2026.01.013_bib0006","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/sc.2008.82","article-title":"The relationship between quality of life and disability across the lifespan for people with spinal cord injury","volume":"47","author":"Barker","year":"2009","journal-title":"Spinal Cord"},{"key":"10.1016\/j.apmr.2026.01.013_bib0007","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/sj.sc.3100336","article-title":"Static respiratory pressures in patients with post-traumatic tetraplegia","volume":"35","author":"Gounden","year":"1997","journal-title":"Spinal Cord"},{"key":"10.1016\/j.apmr.2026.01.013_bib0008","first-page":"1115","article-title":"Rib cage motion and muscle use in high tetraplegics","volume":"133","author":"De Troyer","year":"1986","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.apmr.2026.01.013_bib0009","first-page":"367","article-title":"Mechanism of the postural dependence of vital capacity in tetraplegic subjects","volume":"135","author":"Estenne","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.apmr.2026.01.013_bib0010","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/s41393-020-00595-0","article-title":"Prevalence of sleep-disordered breathing in people with tetraplegia-a systematic review and meta-analysis","volume":"59","author":"Graco","year":"2021","journal-title":"Spinal Cord"},{"key":"10.1016\/j.apmr.2026.01.013_bib0011","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1097\/PHM.0000000000000046","article-title":"Relationship Between pulmonary function and exercise capacity in individuals with spinal cord injury","volume":"93","author":"Battikha","year":"2014","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2026.01.013_bib0012","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/s41394-020-00346-6","article-title":"Effect of repeated locomotor training on ventilatory measures, perceived exertion and walking endurance in persons with motor incomplete spinal cord injury","volume":"6","author":"Panza","year":"2020","journal-title":"Spinal Cord Ser Cases"},{"key":"10.1016\/j.apmr.2026.01.013_bib0013","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1183\/20734735.012616","article-title":"Respiratory problems and management in people with spinal cord injury","volume":"12","author":"Berlowitz","year":"2016","journal-title":"Breathe"},{"key":"10.1016\/j.apmr.2026.01.013_bib0014","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/sc.2015.233","article-title":"Long-term change in respiratory function following spinal cord injury","volume":"54","author":"van Silfhout","year":"2016","journal-title":"Spinal Cord"},{"key":"10.1016\/j.apmr.2026.01.013_bib0015","series-title":"StatPearls Treasure Island (FL)","article-title":"Beta2-Agonists","author":"Hsu","year":"2024"},{"key":"10.1016\/j.apmr.2026.01.013_bib0016","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1378\/chest.101.1.133","article-title":"Effect of a beta 2-agonist (broxaterol) on respiratory muscle strength and endurance in patients with COPD with irreversible airway obstruction","volume":"101","author":"Nava","year":"1992","journal-title":"Chest"},{"key":"10.1016\/j.apmr.2026.01.013_bib0017","first-page":"615","article-title":"Salbutamol, a beta 2-adrenoceptor agonist, increases skeletal muscle strength in young men","volume":"83","author":"Martineau","year":"1992","journal-title":"Clin Sci Lond Engl 1979"},{"key":"10.1016\/j.apmr.2026.01.013_bib0018","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0003-9993(95)80043-3","article-title":"Increased muscle strength in paralyzed patients after spinal cord injury: effect of beta-2 adrenergic agonist","volume":"76","author":"Signorile","year":"1995","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2026.01.013_bib0019","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/S0003-9993(99)90027-8","article-title":"Salbutamol effect in spinal cord injured individuals undergoing functional electrical stimulation training","volume":"80","author":"Murphy","year":"1999","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2026.01.013_bib0020","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s00408-006-0011-6","article-title":"Salmeterol improves pulmonary function in persons with tetraplegia","volume":"184","author":"Grimm","year":"2006","journal-title":"Lung"},{"key":"10.1016\/j.apmr.2026.01.013_bib0021","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.resp.2015.07.001","article-title":"Compensatory muscle activation during forced respiratory tasks in individuals with chronic spinal cord injury","volume":"217","author":"Terson de Paleville","year":"2015","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.apmr.2026.01.013_bib0022","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.apmr.2021.09.019","article-title":"Cause of death trends among persons with spinal cord injury in the United States: 1960-2017","volume":"103","author":"DeVivo","year":"2022","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2026.01.013_bib0023","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/j.apmr.2024.07.007","article-title":"Long-term pulmonary function postspinal cord injury","volume":"105","author":"Sho","year":"2024","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2026.01.013_bib0024","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1164\/rccm.200709-1332OC","article-title":"Longitudinal change in FEV1 and FVC in chronic spinal cord injury","volume":"177","author":"Stolzmann","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.apmr.2026.01.013_bib0025","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1080\/10790268.2008.11753645","article-title":"Spinal Cord Rehabilitation Evidence Research Team. Effects of exercise training and inspiratory muscle training in spinal cord injury: a systematic review","volume":"31","author":"Sheel","year":"2008","journal-title":"J Spinal Cord Med"},{"key":"10.1016\/j.apmr.2026.01.013_bib0026","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1164\/rccm.201209-1739PP","article-title":"\u03b22-agonist therapy in lung disease","volume":"187","author":"Cazzola","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.apmr.2026.01.013_bib0027","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1378\/chest.127.1.149","article-title":"Assessment of airway caliber and bronchodilator responsiveness in subjects with spinal cord injury","volume":"127","author":"Schilero","year":"2005","journal-title":"Chest"},{"key":"10.1016\/j.apmr.2026.01.013_bib0028","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1080\/10790268.2016.1235753","article-title":"Bronchodilator effects of ipratropium bromide and albuterol sulfate among subjects with tetraplegia","volume":"41","author":"Schilero","year":"2018","journal-title":"J Spinal Cord Med"},{"key":"10.1016\/j.apmr.2026.01.013_bib0029","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/0026-0495(91)90015-O","article-title":"Effects of clenbuterol on skeletal muscle mass, body composition, and recovery from surgical stress in senescent rats","volume":"40","author":"Carter","year":"1991","journal-title":"Metabolism"},{"key":"10.1016\/j.apmr.2026.01.013_bib0030","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/0026-0495(94)90054-X","article-title":"Comparison of the effects of salbutamol and clenbuterol on skeletal muscle mass and carcass composition in senescent rats","volume":"43","author":"Carter","year":"1994","journal-title":"Metabolism"},{"key":"10.1016\/j.apmr.2026.01.013_bib0031","doi-asserted-by":"crossref","DOI":"10.1111\/sms.14567","article-title":"Beyond bronchodilation: illuminating the performance benefits of inhaled beta2 -agonists in sports","volume":"34","author":"Hostrup","year":"2024","journal-title":"Scand J Med Sci Sports"},{"key":"10.1016\/j.apmr.2026.01.013_bib0032","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1249\/00005768-199511000-00002","article-title":"The effects of albuterol and isokinetic exercise on the quadriceps muscle group","volume":"27","author":"Caruso","year":"1995","journal-title":"Med Sci Sports Exerc"},{"key":"10.1016\/j.apmr.2026.01.013_bib0033","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1186\/1745-6215-12-264","article-title":"Comparisons against baseline within randomised groups are often used and can be highly misleading","volume":"12","author":"Bland","year":"2011","journal-title":"Trials"},{"key":"10.1016\/j.apmr.2026.01.013_bib0034","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1038\/s41393-018-0203-y","article-title":"Statistical testing for baseline differences between randomised groups is not meaningful","volume":"56","author":"Harvey","year":"2018","journal-title":"Spinal Cord"},{"key":"10.1016\/j.apmr.2026.01.013_bib0035","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.resp.2009.04.002","article-title":"Pulmonary function and spinal cord injury","volume":"166","author":"Schilero","year":"2009","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.apmr.2026.01.013_bib0036","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.apmr.2004.11.033","article-title":"A longitudinal evaluation of sleep and breathing in the first year after cervical spinal cord injury","volume":"86","author":"Berlowitz","year":"2005","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.apmr.2026.01.013_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.smrv.2021.101470","article-title":"Association between autonomic function and obstructive sleep apnea: a systematic review","volume":"57","author":"Dissanayake","year":"2021","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.apmr.2026.01.013_bib0038","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1164\/rccm.201804-0758OC","article-title":"Apnea\u2013hypopnea event duration predicts mortality in men and women in the sleep heart health study","volume":"199","author":"Butler","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.apmr.2026.01.013_bib0039","first-page":"A3326","article-title":"Impact of sleep disorders on daytime function and quality of life in patients with spinal cord injury","volume":"205","author":"Badr","year":"2022","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.apmr.2026.01.013_bib0040","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/s41394-018-0062-y","article-title":"Relationship between autonomic cardiovascular control and obstructive sleep apnoea in persons with spinal cord injury: a retrospective study","volume":"4","author":"Fang","year":"2018","journal-title":"Spinal Cord Ser Cases"},{"key":"10.1016\/j.apmr.2026.01.013_bib0041","doi-asserted-by":"crossref","first-page":"377","DOI":"10.3390\/jpm11050377","article-title":"Effects of respiratory muscle training on baroreflex sensitivity, respiratory function, and serum oxidative stress in acute cervical spinal cord injury","volume":"11","author":"Wang","year":"2021","journal-title":"J Pers Med"},{"key":"10.1016\/j.apmr.2026.01.013_bib0042","doi-asserted-by":"crossref","DOI":"10.1038\/scsandc.2015.10","article-title":"Respiratory muscle training may improve respiratory function and obstructive sleep apnoea in people with cervical spinal cord injury","volume":"1","author":"Boswell-Ruys","year":"2015","journal-title":"Spinal Cord Ser Cases"},{"key":"10.1016\/j.apmr.2026.01.013_bib0043","doi-asserted-by":"crossref","first-page":"3673","DOI":"10.1113\/JP277943","article-title":"Respiratory muscle training in athletes with cervical spinal cord injury: effects on cardiopulmonary function and exercise capacity","volume":"597","author":"Gee","year":"2019","journal-title":"J Physiol"},{"key":"10.1016\/j.apmr.2026.01.013_bib0044","first-page":"153","article-title":"Effects of a beta2-agonist on airway hyperreactivity in subjects with cervical spinal cord injury","volume":"115","author":"DeLuca","year":"1999","journal-title":"Chest"},{"key":"10.1016\/j.apmr.2026.01.013_bib0045","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1007\/s12028-021-01384-0","article-title":"Impact of enteral albuterol on bradycardic events after acute cervical spinal cord injury","volume":"36","author":"Lim-Hing","year":"2022","journal-title":"Neurocrit Care"},{"key":"10.1016\/j.apmr.2026.01.013_bib0046","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.14617","article-title":"Heart rate and blood pressure response improve the prediction of orthostatic cardiovascular dysregulation in persons with chronic spinal cord injury","volume":"8","author":"Wang","year":"2020","journal-title":"Physiol Rep"},{"key":"10.1016\/j.apmr.2026.01.013_bib0047","doi-asserted-by":"crossref","first-page":"S322","DOI":"10.1067\/mai.2002.129966","article-title":"Adverse effects of \u03b2-agonists","volume":"110","author":"Sears","year":"2002","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.apmr.2026.01.013_bib0048","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jemermed.2007.11.056","article-title":"Should acute treatment with inhaled beta agonists be withheld from patients with dyspnea who may have heart failure?","volume":"40","author":"Maak","year":"2011","journal-title":"J Emerg Med"}],"container-title":["Archives of Physical Medicine and Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999326000341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003999326000341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T09:48:13Z","timestamp":1780393693000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003999326000341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0003999326000341"],"URL":"https:\/\/doi.org\/10.1016\/j.apmr.2026.01.013","relation":{},"ISSN":["0003-9993"],"issn-type":[{"value":"0003-9993","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of Albuterol Repetabs on Pulmonary Function in Individuals With Chronic Spinal Cord Injury","name":"articletitle","label":"Article Title"},{"value":"Archives of Physical Medicine and Rehabilitation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.apmr.2026.01.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. on behalf of the American Congress of Rehabilitation Medicine","name":"copyright","label":"Copyright"}]}}