{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T13:41:59Z","timestamp":1773150119874,"version":"3.50.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Applied Radiation and Isotopes"],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1016\/j.apradiso.2007.02.008","type":"journal-article","created":{"date-parts":[[2007,3,28]],"date-time":"2007-03-28T16:03:14Z","timestamp":1175097794000},"page":"827-830","source":"Crossref","is-referenced-by-count":6,"title":["Tritium labelling of several potent fluorinated antipsychotic drugs at high specific activity"],"prefix":"10.1016","volume":"65","author":[{"given":"David G.","family":"Ahern","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne G.","family":"Laseter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crist N.","family":"Filer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.apradiso.2007.02.008_bib1","doi-asserted-by":"crossref","first-page":"239","DOI":"10.2174\/1389557033488169","article-title":"Current strategies for the development of novel antipsychotic drugs","volume":"3","author":"Bolos","year":"2003","journal-title":"Mini-Rev. Med. Chem."},{"key":"10.1016\/j.apradiso.2007.02.008_bib2","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1021\/jo01357a618","article-title":"New trifluoromethylphenothiazine derivatives","volume":"22","author":"Craig","year":"1957","journal-title":"J. Org. Chem."},{"key":"10.1016\/j.apradiso.2007.02.008_bib3","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.apradiso.2004.03.124","article-title":"Colforsin analogues: tritiation and characterization","volume":"61","author":"Egan","year":"2004","journal-title":"Appl. Radiat. Isot."},{"key":"10.1016\/j.apradiso.2007.02.008_bib4","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/(SICI)1099-1344(199902)42:2<169::AID-JLCR178>3.0.CO;2-0","article-title":"Isotopic fractionation of organic compounds in chromatography","volume":"42","author":"Filer","year":"1999","journal-title":"J. Label. Cpd. Radiopharm."},{"key":"10.1016\/j.apradiso.2007.02.008_bib5","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1021\/jm50004a007","article-title":"Chemistry and pharmacology of CNS depressants related to 4-(4-hydroxy-4-phenylpiperidino)butyrophenone. I. Synthesis and screening data in mice","volume":"1","author":"Janssen","year":"1959","journal-title":"J. Med. Pharm. Chem."},{"key":"10.1016\/j.apradiso.2007.02.008_bib6","doi-asserted-by":"crossref","first-page":"S166","DOI":"10.1055\/s-2004-832674","article-title":"Sigma receptors and sigma ligands: background to a pharmacological enigma","volume":"37","author":"Leonard","year":"2004","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.apradiso.2007.02.008_bib7","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.bmcl.2003.09.083","article-title":"Conformationally-flexible benzamide analogues as dopamime D3 and sigma 2 receptor ligands","volume":"14","author":"Mach","year":"2004","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.apradiso.2007.02.008_bib8","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1002\/jlcr.2580150160","article-title":"Alumina catalyzed tritium exchange of enolizable hydrogens","volume":"15","author":"Muccino","year":"1978","journal-title":"J. Label. Cpd. Radiopharm."},{"key":"10.1016\/j.apradiso.2007.02.008_bib9","first-page":"643","article-title":"Receptor occupancy research using PET\/SPECT","volume":"21","author":"Nakashima","year":"1999","journal-title":"No No Kagaku"},{"key":"10.1016\/j.apradiso.2007.02.008_bib10","doi-asserted-by":"crossref","first-page":"24","DOI":"10.4024\/4NA01A.01.01","article-title":"Haloperidol regulates the binding of guanine nucleotides to synaptic membranes through the NMDA receptor","volume":"1","author":"Natsvlishvilli","year":"2001","journal-title":"J. Biol. Phys. Chem."},{"key":"10.1016\/j.apradiso.2007.02.008_bib11","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0924-977X(02)00078-0","article-title":"The influence of dyslipidemia on the plasma protein and lipoprotein distribution of haloperidol","volume":"13","author":"Procyshyn","year":"2003","journal-title":"Eur. Neuropsychopharm."},{"key":"10.1016\/j.apradiso.2007.02.008_bib12","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/sj.bjp.0705009","article-title":"In vitro evidence for the presence of [3H] haloperidol uptake in rat brain","volume":"138","author":"Ruiu","year":"2003","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.apradiso.2007.02.008_bib13","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1517\/14728222.10.4.515","article-title":"Targeting the dopamine D2 receptor in schizophrenia","volume":"10","author":"Seeman","year":"2006","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.apradiso.2007.02.008_bib14","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1358\/mf.2005.27.5.908643","article-title":"Research on adverse drug events. I. Muscarinic M3 receptor binding affinity could predict the risk of antipsychotics to induce type 2 diabetes","volume":"27","author":"Silvestre","year":"2005","journal-title":"Methods Findings Exp. Clin. Pharm."},{"key":"10.1016\/j.apradiso.2007.02.008_bib15","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/jlcr.2580240713","article-title":"Tritium labelled compounds of high specific activity. III. Trifluoperazine","volume":"24","author":"Zolyomi","year":"1987","journal-title":"J. Label. Cpd. Radiopharm."}],"container-title":["Applied Radiation and Isotopes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969804307000759?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969804307000759?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,8]],"date-time":"2019-01-08T09:52:15Z","timestamp":1546941135000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969804307000759"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["S0969804307000759"],"URL":"https:\/\/doi.org\/10.1016\/j.apradiso.2007.02.008","relation":{},"ISSN":["0969-8043"],"issn-type":[{"value":"0969-8043","type":"print"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}