{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T20:47:45Z","timestamp":1789850865431,"version":"4.0.1"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["3777\/1-2"],"award-info":[{"award-number":["3777\/1-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Werner Siemens Foundation"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Applied Radiation and Isotopes"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.apradiso.2018.09.006","type":"journal-article","created":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T16:14:31Z","timestamp":1536423271000},"page":"149-155","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Comparative immuno-Cerenkov luminescence and -PET imaging enables detection of PSMA+ tumors in mice using 64Cu-radiolabeled monoclonal antibodies"],"prefix":"10.1016","volume":"143","author":[{"given":"Florian C.","family":"Maier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna-Maria","family":"Wild","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas","family":"Kirchen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Holm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Fuchs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Schwenck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2412-5361","authenticated-orcid":false,"given":"Andreas","family":"Maurer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Wiehr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.apradiso.2018.09.006_bib1","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1002\/pros.21176","article-title":"High-resolution animal PET imaging of prostate cancer xenografts with three different 64Cu-labeled antibodies against native cell-adherent PSMA","volume":"70","author":"Alt","year":"2010","journal-title":"Prostate"},{"key":"10.1016\/j.apradiso.2018.09.006_bib2","doi-asserted-by":"crossref","first-page":"5846","DOI":"10.1158\/0008-5472.CAN-14-0764","article-title":"In vivo localization of (9)(0)Y and (1)(7)(7)Lu radioimmunoconjugates using Cerenkov luminescence imaging in a disseminated murine leukemia model","volume":"74","author":"Balkin","year":"2014","journal-title":"Cancer Res."},{"key":"10.1016\/j.apradiso.2018.09.006_bib3","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2967\/jnumed.108.056374","article-title":"Performance evaluation of the inveon dedicated PET preclinical tomograph based on the NEMA NU-4 standards","volume":"50","author":"Bao","year":"2009","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.apradiso.2018.09.006_bib4","first-page":"3192","article-title":"Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature","volume":"59","author":"Chang","year":"1999","journal-title":"Cancer Res."},{"key":"10.1016\/j.apradiso.2018.09.006_bib5","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40658-017-0181-8","article-title":"Cerenkov luminescence imaging: physics principles and potential applications in biomedical sciences","volume":"4","author":"Ciarrocchi","year":"2017","journal-title":"EJNMMI Phys."},{"key":"10.1016\/j.apradiso.2018.09.006_bib6","doi-asserted-by":"crossref","first-page":"175","DOI":"10.2967\/jnumed.116.178780","article-title":"Cerenkov luminescence imaging as a modality to evaluate antibody-based PET radiotracers","volume":"58","author":"D\u2032Souza","year":"2017","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.apradiso.2018.09.006_bib7","doi-asserted-by":"crossref","first-page":"175","DOI":"10.2967\/jnumed.116.178780","article-title":"Cerenkov luminescence imaging as a modality to evaluate antibody-based PET radiotracers","volume":"58","author":"D\u2032Souza","year":"2017","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.apradiso.2018.09.006_bib8","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/B978-0-12-411638-2.00006-9","article-title":"Cerenkov imaging","volume":"124","author":"Das","year":"2014","journal-title":"Adv. Cancer Res."},{"key":"10.1016\/j.apradiso.2018.09.006_bib9","doi-asserted-by":"crossref","first-page":"3398","DOI":"10.7150\/thno.20919","article-title":"Towards translational immunoPET\/MR imaging of invasive pulmonary Aspergillosis: the humanised monoclonal antibody JF5 detects aspergillus lung infections in vivo","volume":"7","author":"Davies","year":"2017","journal-title":"Theranostics"},{"key":"10.1016\/j.apradiso.2018.09.006_bib10","doi-asserted-by":"crossref","first-page":"606","DOI":"10.2967\/jnumed.108.058487","article-title":"PET imaging of prostate cancer xenografts with a highly specific antibody against the prostate-specific membrane antigen","volume":"50","author":"Elsasser-Beile","year":"2009","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.apradiso.2018.09.006_bib11","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1002\/pros.20367","article-title":"A new generation of monoclonal and recombinant antibodies against cell-adherent prostate specific membrane antigen for diagnostic and therapeutic targeting of prostate cancer","volume":"66","author":"Elsasser-Beile","year":"2006","journal-title":"Prostate"},{"key":"10.1016\/j.apradiso.2018.09.006_bib12","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/s00259-012-2060-9","article-title":"PET\/MRI in infectious and inflammatory diseases: will it be a useful improvement?","volume":"39","author":"Glaudemans","year":"2012","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.apradiso.2018.09.006_bib13","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s40336-016-0183-x","article-title":"Cerenkov luminescence imaging (CLI) for image-guided cancer surgery","volume":"4","author":"Grootendorst","year":"2016","journal-title":"Clin. Transl. Imaging"},{"key":"10.1016\/j.apradiso.2018.09.006_bib14","doi-asserted-by":"crossref","first-page":"891","DOI":"10.2967\/jnumed.116.181032","article-title":"Intraoperative assessment of tumor resection margins in breast-conserving surgery using (18)F-FDG cerenkov luminescence imaging: a first-in-human feasibility study","volume":"58","author":"Grootendorst","year":"2017","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.apradiso.2018.09.006_bib15","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.2967\/jnumed.110.076174","article-title":"89Zr-DFO-J591 for immunoPET of prostate-specific membrane antigen expression in vivo","volume":"51","author":"Holland","year":"2010","journal-title":"J. Nucl. Med."},{"issue":"177\u2013186","key":"10.1016\/j.apradiso.2018.09.006_bib16","first-page":"171","article-title":"Intraoperative imaging of positron emission tomographic radiotracers using Cerenkov luminescence emissions","volume":"10","author":"Holland","year":"2011","journal-title":"Mol. Imaging"},{"key":"10.1016\/j.apradiso.2018.09.006_bib17","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1038\/nbt1142","article-title":"Engineered antibody fragments and the rise of single domains","volume":"23","author":"Holliger","year":"2005","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.apradiso.2018.09.006_bib18","first-page":"227","article-title":"Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen","volume":"53","author":"Israeli","year":"1993","journal-title":"Cancer Res."},{"key":"10.1016\/j.apradiso.2018.09.006_bib19","doi-asserted-by":"crossref","DOI":"10.18632\/oncotarget.11795","article-title":"Correlation between positron emission tomography and Cerenkov luminescence imaging in vivo and ex vivo using 64Cu-labeled antibodies in a neuroblastoma mouse model","author":"Maier","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.apradiso.2018.09.006_bib20","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/nrurol.2016.26","article-title":"Current use of PSMA-PET in prostate cancer management","volume":"13","author":"Maurer","year":"2016","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.apradiso.2018.09.006_bib21","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/s11307-013-0624-0","article-title":"Evaluation of 89Zr-rituximab tracer by Cerenkov luminescence imaging and correlation with PET in a humanized transgenic mouse model to image NHL","volume":"15","author":"Natarajan","year":"2013","journal-title":"Mol. Imaging Biol.: MIB: Off. Publ. Acad. Mol. Imaging"},{"key":"10.1016\/j.apradiso.2018.09.006_bib22","doi-asserted-by":"crossref","first-page":"N355","DOI":"10.1088\/0031-9155\/54\/16\/N01","article-title":"Optical imaging of Cerenkov light generation from positron-emitting radiotracers","volume":"54","author":"Robertson","year":"2009","journal-title":"Phys. Med. Biol."},{"key":"10.1016\/j.apradiso.2018.09.006_bib23","doi-asserted-by":"crossref","first-page":"E1026","DOI":"10.1073\/pnas.1518836113","article-title":"ImmunoPET\/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo","volume":"113","author":"Rolle","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.apradiso.2018.09.006_bib24","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.2967\/jnumed.110.076521","article-title":"Cerenkov luminescence imaging of medical isotopes","volume":"51","author":"Ruggiero","year":"2010","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.apradiso.2018.09.006_bib25","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/s00259-016-3490-6","article-title":"Comparison of 68Ga-labelled PSMA-11 and 11C-choline in the detection of prostate cancer metastases by PET\/CT","volume":"44","author":"Schwenck","year":"2017","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.apradiso.2018.09.006_bib26","doi-asserted-by":"crossref","first-page":"3112","DOI":"10.1021\/cr900351r","article-title":"Molecular imaging of inflammation\/infection: nuclear medicine and optical imaging agents and methods","volume":"110","author":"Signore","year":"2010","journal-title":"Chem. Rev."},{"key":"10.1016\/j.apradiso.2018.09.006_bib27","first-page":"280","article-title":"Optical imaging of radioisotopes: a novel multimodal approach to molecular imaging","volume":"56","author":"Spinelli","year":"2012","journal-title":"Q. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.apradiso.2018.09.006_bib28","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1038\/nm.3323","article-title":"Quantitative imaging of disease signatures through radioactive decay signal conversion","volume":"19","author":"Thorek","year":"2013","journal-title":"Nat. Med."},{"key":"10.1016\/j.apradiso.2018.09.006_bib29","doi-asserted-by":"crossref","first-page":"444","DOI":"10.2967\/jnumed.114.148544","article-title":"Intratherapeutic biokinetic measurements, dosimetry parameter estimates, and monitoring of treatment efficacy using Cerenkov luminescence imaging in preclinical radionuclide therapy","volume":"56","author":"Timmermand","year":"2015","journal-title":"J. Nucl. Med."},{"issue":"Suppl. 1","key":"10.1016\/j.apradiso.2018.09.006_bib30","first-page":"164S","article-title":"The promise of immuno-PET in radioimmunotherapy","volume":"46","author":"Verel","year":"2005","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.apradiso.2018.09.006_bib31","doi-asserted-by":"crossref","first-page":"11S","DOI":"10.2967\/jnumed.113.129221","article-title":"Preclinical and translational PET\/MR Imaging","volume":"55","author":"Wehrl","year":"2014","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.apradiso.2018.09.006_bib32","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1002\/pros.22794","article-title":"Pharmacokinetics and PET imaging properties of two recombinant anti-PSMA antibody fragments in comparison to their parental antibody","volume":"74","author":"Wiehr","year":"2014","journal-title":"Prostate"},{"key":"10.1016\/j.apradiso.2018.09.006_bib33","doi-asserted-by":"crossref","DOI":"10.18632\/oncotarget.7770","article-title":"New pathogen-specific immunoPET\/MR tracer for molecular imaging of a systemic bacterial infection","author":"Wiehr","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.apradiso.2018.09.006_bib34","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1002\/pros.21090","article-title":"Three conformational antibodies specific for different PSMA epitopes are promising diagnostic and therapeutic tools for prostate cancer","volume":"70","author":"Wolf","year":"2010","journal-title":"Prostate"},{"key":"10.1016\/j.apradiso.2018.09.006_bib35","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/PPO.0b013e31817b07ae","article-title":"Antibodies for molecular imaging of cancer","volume":"14","author":"Wu","year":"2008","journal-title":"Cancer J."},{"key":"10.1016\/j.apradiso.2018.09.006_bib36","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.2967\/jnumed.111.092965","article-title":"Harnessing the power of radionuclides for optical imaging: Cerenkov luminescence imaging","volume":"52","author":"Xu","year":"2011","journal-title":"J. Nucl. Med."}],"container-title":["Applied Radiation and Isotopes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969804318300915?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969804318300915?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,9]],"date-time":"2020-11-09T07:54:25Z","timestamp":1604908465000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969804318300915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":36,"alternative-id":["S0969804318300915"],"URL":"https:\/\/doi.org\/10.1016\/j.apradiso.2018.09.006","relation":{},"ISSN":["0969-8043"],"issn-type":[{"value":"0969-8043","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative immuno-Cerenkov luminescence and -PET imaging enables detection of PSMA+ tumors in mice using 64Cu-radiolabeled monoclonal antibodies","name":"articletitle","label":"Article Title"},{"value":"Applied Radiation and Isotopes","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.apradiso.2018.09.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}