{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:14:45Z","timestamp":1792174485007,"version":"4.4.0"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,11]],"date-time":"2022-12-11T00:00:00Z","timestamp":1670716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012774","name":"Innovationsfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018693","name":"Horizon 2020","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018693","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Applied Radiation and Isotopes"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.apradiso.2022.110612","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T19:52:44Z","timestamp":1670529164000},"page":"110612","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Improved procedures for production and purification of 135La from enriched [135Ba]BaCO3 on a 16.5\u00a0MeV cyclotron"],"prefix":"10.1016","volume":"192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6843-9237","authenticated-orcid":false,"given":"Kristina S\u00f8borg","family":"Pedersen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Deville","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"S\u00f8ndergaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikael","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas I.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.apradiso.2022.110612_bib1","doi-asserted-by":"crossref","DOI":"10.1103\/PhysRevC.97.034312","article-title":"Half-lives of 132La and 135La","volume":"97","author":"Abel","year":"2018","journal-title":"Phys. Rev. C"},{"key":"10.1016\/j.apradiso.2022.110612_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-47137-0","article-title":"Production and in vivo PET\/CT imaging of the theranostic pair 132\/135La","volume":"9","author":"Aluicio-Sarduy","year":"2019","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.apradiso.2022.110612_bib3","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1002\/chem.201905202","article-title":"Establishing radiolanthanum chemistry for targeted nuclear medicine applications","volume":"26","author":"Aluicio-Sarduy","year":"2020","journal-title":"Chem. Eur J."},{"issue":"19","key":"10.1016\/j.apradiso.2022.110612_bib4","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1002\/cmdc.202100135","article-title":"Recent advances in radiometals for combined imaging and therapy in cancer","volume":"16","author":"\u00c1lvarez","year":"2021","journal-title":"ChemMedChem"},{"issue":"7","key":"10.1016\/j.apradiso.2022.110612_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/diagnostics11071235","article-title":"Production, purification, and applications of a potential theranostic pair: cobalt-55 and cobalt-58m","volume":"11","author":"Barrett","year":"2021","journal-title":"Diagnostics"},{"issue":"11","key":"10.1016\/j.apradiso.2022.110612_bib6","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1007\/s00259-006-0187-2","article-title":"Auger radiation targeted into DNA: a therapy perspective","volume":"33","author":"Buchegger","year":"2006","journal-title":"Eur. J. Nucl. Med. Mol. Imag."},{"issue":"2","key":"10.1016\/j.apradiso.2022.110612_bib7","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/BF02347463","article-title":"The stability of some metal EDTA, DTPA and DOTA complexes: application as tracers in groundwater studies","volume":"241","author":"Byeg\u00e5rd","year":"1999","journal-title":"J. Radioanal. Nucl. Chem."},{"issue":"3","key":"10.1016\/j.apradiso.2022.110612_bib8","article-title":"Electrochemical separation of 132\/135La theranostic pair from proton irradiated Ba target\u2019, Separation and Purification Technology","volume":"280","author":"Chakravarty","year":"2022","journal-title":"Elsevier B.V."},{"key":"10.1016\/j.apradiso.2022.110612_bib9","first-page":"1","volume":"vols. 94\u201395","author":"Filosofov","year":"2021"},{"key":"10.1016\/j.apradiso.2022.110612_bib10","first-page":"S24","article-title":"135La for Auger-based therapy: preparation, imaging and emission","volume":"58","author":"Fonslet","year":"2015","journal-title":"J. Label. Compd. Radiopharm."},{"key":"10.1016\/j.apradiso.2022.110612_bib11","article-title":"135La as an Auger-electron emitter for targeted internal radiotherapy","volume":"63","author":"Fonslet","year":"2018","journal-title":"Phys. Med. Biol."},{"key":"10.1016\/j.apradiso.2022.110612_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.apradiso.2020.109079","article-title":"165Er: a new candidate for Auger electron therapy and its possible cyclotron production from natural holmium targets","volume":"159","author":"Gracheva","year":"2020","journal-title":"Appl. Radiat. Isot."},{"issue":"3","key":"10.1016\/j.apradiso.2022.110612_bib13","doi-asserted-by":"crossref","first-page":"861","DOI":"10.5506\/APhysPolB.51.861","article-title":"Investigation of the production of the auger electron emitter 135La using medical cyclotrons","volume":"51","author":"Jastrz\u0229bski","year":"2020","journal-title":"Acta Phys. Pol. B"},{"issue":"27","key":"10.1016\/j.apradiso.2022.110612_bib14","first-page":"1","article-title":"Auger electrons for cancer therapy \u2013 a review\u2019, EJNMMI Radiopharmacy and Chemistry","volume":"4","author":"Ku","year":"2019","journal-title":"EJNMMI Radiopharm. Chem."},{"issue":"11","key":"10.1016\/j.apradiso.2022.110612_bib15","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1515\/ract-2015-2427","article-title":"Production of no-carrier-added 135La at an 18 MeV cyclotron and its purification for investigations at a concentration range down to 10\u00e2-15 mol\/L","volume":"103","author":"Mansel","year":"2015","journal-title":"Radiochim. Acta"},{"issue":"1","key":"10.1016\/j.apradiso.2022.110612_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-020-79198-x","article-title":"High yield cyclotron production of a novel 133\/135La theranostic pair for nuclear medicine","volume":"10","author":"Nelson","year":"2020","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.apradiso.2022.110612_bib17","doi-asserted-by":"crossref","first-page":"584","DOI":"10.2967\/jnumed.121.262459","article-title":"First in vivo and phantom imaging of cyclotron-produced 133La as a theranostic radionuclide for 225Ac and 135La","volume":"63","author":"Nelson","year":"2022","journal-title":"J. Nucl. Med."},{"issue":"S1","key":"10.1016\/j.apradiso.2022.110612_bib18","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1016\/S0969-8051(21)00297-3","article-title":"Fast, efficient, one-step purification of cyclotron produced lanthanum-135 using HDEHP-based resin and dilute hydrochloric acid","volume":"96\u201397","author":"Nielsen","year":"2021","journal-title":"Nucl. Med. Biol."},{"issue":"April","key":"10.1016\/j.apradiso.2022.110612_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.apradiso.2017.04.028","article-title":"A systematic study on the utility of CHX-A\u2019\u2019-DTPA-NCS and NOTA-NCS as bifunctional chelators for 177Lu radiopharmaceuticals","volume":"127","author":"Pandey","year":"2017","journal-title":"Appl. Radiat. Isot."},{"issue":"3","key":"10.1016\/j.apradiso.2022.110612_bib20","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.talanta.2010.01.008","article-title":"Distribution coefficients of 60 elements on TODGA resin: application to Ca, Lu, Hf, U and Th isotope geochemistry","volume":"81","author":"Pourmand","year":"2010","journal-title":"Talanta"},{"issue":"2","key":"10.1016\/j.apradiso.2022.110612_bib21","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0168-583X(91)95645-T","article-title":"Thin-target cross sections of proton-induced reactions on barium and solar cosmic ray production rates of xenon-isotopes in lunar surface materials","volume":"53","author":"Prescher","year":"1991","journal-title":"Nucl. Instrum. Methods Phys. Res. B"},{"issue":"1","key":"10.1016\/j.apradiso.2022.110612_bib22","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1039\/C3CS60304K","article-title":"Matching chelators to radiometals for radiopharmaceuticals","volume":"43","author":"Price","year":"2014","journal-title":"Chem. Soc. Rev."},{"issue":"4","key":"10.1016\/j.apradiso.2022.110612_bib23","first-page":"394","article-title":"Meitner-Auger electron emitters for targeted radionuclide therapy: mercury-197m\/g and antimony-119","volume":"14","author":"Randhawa","year":"2021","journal-title":"Curr. Rad."},{"issue":"10","key":"10.1016\/j.apradiso.2022.110612_bib24","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1016\/j.apradiso.2010.03.010","article-title":"Study of activation cross sections of proton induced reactions on barium: production of 131Ba -> 131Cs","volume":"68","author":"T\u00e1rk\u00e1nyi","year":"2010","journal-title":"Appl. Radiat. Isot."},{"issue":"13\u201314","key":"10.1016\/j.apradiso.2022.110612_bib26","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1016\/j.ccr.2009.03.013","article-title":"The coordination chemistry of 1,4,7,10-tetraazacyclododecane-N,N\u2032,N\u2033,N\u2032\u2033-tetra acetic acid (H4DOTA): structural overview and analyses on structure-stability relationships","volume":"253","author":"Viola-Villegas","year":"2009","journal-title":"Coord. Chem. Rev."}],"container-title":["Applied Radiation and Isotopes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969804322004973?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969804322004973?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T04:22:58Z","timestamp":1760847778000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969804322004973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":25,"alternative-id":["S0969804322004973"],"URL":"https:\/\/doi.org\/10.1016\/j.apradiso.2022.110612","relation":{},"ISSN":["0969-8043"],"issn-type":[{"value":"0969-8043","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Improved procedures for production and purification of 135La from enriched [135Ba]BaCO3 on a 16.5\u00a0MeV cyclotron","name":"articletitle","label":"Article Title"},{"value":"Applied Radiation and Isotopes","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.apradiso.2022.110612","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"110612"}}