{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T12:08:04Z","timestamp":1788782884570,"version":"build-2803163510"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100009688","name":"Ural'skij federal'nyj universitet Fakul'tet povysenia kvalifikacii prepodavatelej i professional'noj perepodgotovki","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009688","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Applied Radiation and Isotopes"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.apradiso.2026.112846","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:30:50Z","timestamp":1786033850000},"page":"112846","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Optimization of patient dose and image quality for positron emission tomography-computed tomography"],"prefix":"10.1016","volume":"237","author":[{"given":"Fatma","family":"Mostafa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba A.","family":"Saudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.A.","family":"EL Hagg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roya","family":"BoudaghiMalidarreh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hesham M.H.","family":"Zakaly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.apradiso.2026.112846_bib1","doi-asserted-by":"crossref","first-page":"338","DOI":"10.2967\/jnmt.125.270382","article-title":"Optimizing dose reduction of 18F-FDG in oncology PET\/CT: exploring strategies to minimize radiation exposure while maintaining diagnostic efficacy","volume":"53","author":"Al","year":"2025","journal-title":"J. Nucl. Med. Technol."},{"issue":"6","key":"10.1016\/j.apradiso.2026.112846_bib2","first-page":"1017","article-title":"PET\/CT scanner instrumentation, challenges, and solutions","volume":"42","author":"Alessio","year":"2004","journal-title":"Radiol. Clin."},{"issue":"1","key":"10.1016\/j.apradiso.2026.112846_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s40658-020-00287-x","article-title":"CT protocol optimisation in PET\/CT: a systematic review","volume":"7","author":"Bertolini","year":"2020","journal-title":"EJNMMI Phys."},{"issue":"2","key":"10.1016\/j.apradiso.2026.112846_bib4","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1007\/s00259-014-2961-x","article-title":"FDG PET\/CT: EANM procedure guidelines for tumour imaging: version 2.0","volume":"42","author":"Boellaard","year":"2015","journal-title":"Eur. J. Nucl. Med. Mol. Imag."},{"issue":"8","key":"10.1016\/j.apradiso.2026.112846_bib5","article-title":"Radiation dose optimization in radiology: a comprehensive review of safeguarding patients and preserving image fidelity","volume":"16","author":"Dudhe","year":"2024","journal-title":"Cureus"},{"issue":"4","key":"10.1016\/j.apradiso.2026.112846_bib6","article-title":"Dose estimation in patients from different protocols of 18F-FDG PET\/CT studies and analysis of optimization strategies","volume":"44","author":"Dwivedi","year":"2024","journal-title":"J. Radiol. Prot."},{"issue":"3","key":"10.1016\/j.apradiso.2026.112846_bib7","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1007\/s00330-011-2056-z","article-title":"Computed tomography: old ideas and new technology","volume":"21","author":"Fleischmann","year":"2011","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.apradiso.2026.112846_bib8","series-title":"Multi-Slice and dual-source CT in Cardiac Imaging: Principles \u2013 Protocols \u2013 Indications","first-page":"15","article-title":"Multi-slice CT technology","author":"Flohr","year":"2011"},{"issue":"1","key":"10.1016\/j.apradiso.2026.112846_bib9","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s40336-024-00675-8","article-title":"Dose optimization in adult PET imaging: a balance between patient exposure and image quality. Literature review and future perspectives","volume":"13","author":"Guglielmo","year":"2025","journal-title":"Clin Transl Imaging"},{"key":"10.1016\/j.apradiso.2026.112846_bib10","series-title":"Computed Tomography: Principles, Designs, Artifacts, and Recent Advances","first-page":"375","year":"2009"},{"issue":"1","key":"10.1016\/j.apradiso.2026.112846_bib11","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1118\/1.598470","article-title":"Multi-slice helical CT: scan and reconstruction","volume":"26","author":"Hu","year":"1999","journal-title":"Med. Phys."},{"issue":"2\u20134","key":"10.1016\/j.apradiso.2026.112846_bib12","first-page":"1","article-title":"The recommendations of the international commission on radiological protection. ICRP publication 103","volume":"37","year":"2007","journal-title":"Ann. ICRP"},{"issue":"1\u20132","key":"10.1016\/j.apradiso.2026.112846_bib13","first-page":"1","article-title":"Radiation dose to patients from radiopharmaceuticals. ICRP publication 106","volume":"38","year":"2008","journal-title":"Ann. ICRP"},{"issue":"1","key":"10.1016\/j.apradiso.2026.112846_bib14","first-page":"12","article-title":"Deep learning-based segmentation of diffuse large B-cell lymphoma in 18F-FDG PET images","volume":"3","author":"Keshavarz","year":"2025","journal-title":"Int J Biol Med Sci Technol"},{"issue":"3","key":"10.1016\/j.apradiso.2026.112846_bib15","article-title":"Variability and reliability of normal liver 18F-FDG standardized uptake value in relation to placement of volume of interest","volume":"16","author":"Liu","year":"2019","journal-title":"Iran. J. Radiol."},{"issue":"3 Suppl. l","key":"10.1016\/j.apradiso.2026.112846_bib16","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1016\/j.ijrobp.2009.06.091","article-title":"Radiation dose-volume effects in the lung","volume":"76","author":"Marks","year":"2010","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"1","key":"10.1016\/j.apradiso.2026.112846_bib17","first-page":"27","article-title":"Strategies for reducing radiation dose in CT","volume":"47","author":"McCollough","year":"2009","journal-title":"Radiol. Clin."},{"issue":"1","key":"10.1016\/j.apradiso.2026.112846_bib18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/mp.16862","article-title":"Ultra-low dose CT scanning for PET\/CT","volume":"51","author":"Mostafapour","year":"2024","journal-title":"Med. Phys."},{"issue":"5","key":"10.1016\/j.apradiso.2026.112846_bib19","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.acra.2018.07.014","article-title":"Body weight-based protocols during whole body FDG PET\/CT significantly reduces radiation dose without compromising image quality: findings in a large cohort study","volume":"26","author":"Saade","year":"2019","journal-title":"Acad. Radiol."},{"issue":"10","key":"10.1016\/j.apradiso.2026.112846_bib20","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1097\/RLU.0000000000001780","article-title":"Enhanced application of 18F-FDG PET\/CT in bladder cancer by adding early dynamic acquisition to a standard delayed PET protocol","volume":"42","author":"Yoon","year":"2017","journal-title":"Clin. Nucl. Med."}],"container-title":["Applied Radiation and Isotopes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969804326004306?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969804326004306?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T11:17:11Z","timestamp":1788779831000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969804326004306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":20,"alternative-id":["S0969804326004306"],"URL":"https:\/\/doi.org\/10.1016\/j.apradiso.2026.112846","relation":{},"ISSN":["0969-8043"],"issn-type":[{"value":"0969-8043","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Optimization of patient dose and image quality for positron emission tomography-computed tomography","name":"articletitle","label":"Article Title"},{"value":"Applied Radiation and Isotopes","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.apradiso.2026.112846","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112846"}}