{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:48:03Z","timestamp":1759366083708,"version":"build-2065373602"},"reference-count":32,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T00:00:00Z","timestamp":1626134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Atenci\u00f3n Primaria"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.aprim.2021.102171","type":"journal-article","created":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T13:10:22Z","timestamp":1637068222000},"page":"102171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fracturas de cadera en pacientes tratados con f\u00e1rmacos antipsic\u00f3ticos. Estudio de cohortes hist\u00f3ricas en Catalu\u00f1a"],"prefix":"10.1016","volume":"54","author":[{"given":"Susana","family":"Gonz\u00e1lez Tej\u00f3n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Montserrat","family":"Ibarra Jato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Isabel","family":"Fern\u00e1ndez San Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Prats Uribe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordi","family":"Real Gatius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Miguel","family":"Martin-Lopez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.aprim.2021.102171_bib0165","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.medcli.2011.11.030","article-title":"Estimate of the 10-year risk of osteoporotic fractures in the Spanish population","volume":"140","author":"Gonz\u00e1lez L\u00f3pez-Valc\u00e1rcel","year":"2013","journal-title":"Med Clin (Barc)."},{"key":"10.1016\/j.aprim.2021.102171_bib0170","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.bone.2007.10.001","article-title":"Epidemiology of hip fracture in the elderly in Spain","volume":"42","author":"Alvarez-Nebreda","year":"2008","journal-title":"Bone."},{"key":"10.1016\/j.aprim.2021.102171_bib0175","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.aprim.2016.01.010","article-title":"Fracturas de cadera y consumo de psicof\u00e1rmacos en un centro de salud urbano","volume":"48","author":"P\u00e9rez Caballero","year":"2016","journal-title":"Aten Primaria."},{"key":"10.1016\/j.aprim.2021.102171_bib0180","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1176\/appi.ajp.161.8.1334","article-title":"Physical health monitoring of patients with schizophrenia","volume":"161","author":"Marder","year":"2004","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.aprim.2021.102171_bib0185","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1192\/bjp.bp.106.023671","article-title":"Risk of hip fracture in patients with a history of schizophrenia","volume":"190","author":"Howard","year":"2007","journal-title":"Br J Psychiatry."},{"issue":"2 Suppl","key":"10.1016\/j.aprim.2021.102171_bib0190","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1177\/0269881107088435","article-title":"A review of the association between antipsychotic use and hyperprolactinaemia","volume":"22","author":"Bushe","year":"2008","journal-title":"J Psychopharmacol."},{"key":"10.1016\/j.aprim.2021.102171_bib0195","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1111\/j.1365-2850.2009.01472.x","article-title":"Antipsychotic-induced hyperprolactinaemia in patients with schizophrenia: Considerations in relation to bone mineral density","volume":"16","author":"Stubbs","year":"2009","journal-title":"J Psychiatr Ment Health Nurs."},{"key":"10.1016\/j.aprim.2021.102171_bib0200","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/YCO.0b013e328355e1ac","article-title":"Osteoporosis and fracture risk in people with schizophrenia","volume":"25","author":"Kishimoto","year":"2012","journal-title":"Curr Opin Psychiatry."},{"key":"10.1016\/j.aprim.2021.102171_bib0205","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1007\/s00198-016-3881-3","article-title":"Use of antipsychotics increases the risk of fracture: a systematic review and meta-analysis","volume":"28","author":"Lee","year":"2017","journal-title":"Osteoporos Int."},{"key":"10.1016\/j.aprim.2021.102171_bib0210","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s11914-016-0325-0","article-title":"Lower bone mineral density at the hip and lumbar spine in people with psychosis versus controls: a comprehensive review and skeletal site-specific meta-analysis","volume":"14","author":"Gomez","year":"2016","journal-title":"Curr Osteoporos Rep."},{"key":"10.1016\/j.aprim.2021.102171_bib0215","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.genhosppsych.2015.01.004","article-title":"Schizophrenia and the risk of fractures: A systematic review and comparative meta-analysis","volume":"37","author":"Stubbs","year":"2015","journal-title":"Gen Hosp Psychiatry."},{"key":"10.1016\/j.aprim.2021.102171_bib0220","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1111\/acps.12313","article-title":"A meta-analysis of prevalence estimates and moderators of low bone mass in people with schizophrenia","volume":"130","author":"Stubbs","year":"2014","journal-title":"Acta Psychiatr Scand."},{"key":"10.1016\/j.aprim.2021.102171_bib0225","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1097\/JCP.0000000000000647","article-title":"Atypical antipsychotics and the risk of falls and fractures among older adults an emulation analysis and an evaluation of additional confounding control strategies","volume":"37","author":"Ramcharran","year":"2017","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.aprim.2021.102171_bib0230","first-page":"1","article-title":"Prevalence of schizophrenia and related disorders in Malaga (Spain): results using multiple clinical databases","volume":"25","author":"Moreno-K\u00fcstner","year":"2014","journal-title":"Epidemiol Psychiatr Sci."},{"key":"10.1016\/j.aprim.2021.102171_bib0235","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.bone.2005.07.005","article-title":"Risk of hip\/femur fractures in patients using antipsychotics","volume":"37","author":"Hugenholtz","year":"2005","journal-title":"Bone."},{"key":"10.1016\/j.aprim.2021.102171_bib0240","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1007\/s00198-008-0826-5","article-title":"Antipsychotic use and the risk of hip\/femur fracture: A population-based case-control study","volume":"20","author":"Pouwels","year":"2009","journal-title":"Osteoporos Int."},{"key":"10.1016\/j.aprim.2021.102171_bib0245","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s00198-005-0065-y","article-title":"Anxiolytics, sedatives, antidepressants, neuroleptics and the risk of fracture","volume":"17","author":"Vestergaard","year":"2006","journal-title":"Osteoporos Int."},{"key":"10.1016\/j.aprim.2021.102171_bib0250","first-page":"3","article-title":"Antypsychotic use and the risk of hip fracture among community dwelling person with alzheimer's disease","volume":"78","author":"Kopen","year":"2017","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.aprim.2021.102171_bib0255","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s40120-016-0060-6","article-title":"Risk of adverse outcomes for older people with dementia prescribe antipsychotic medication: a population based e-cohort study","volume":"6","author":"Dennis","year":"2017","journal-title":"Neurol Ther"},{"key":"10.1016\/j.aprim.2021.102171_bib0260","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.medcli.2012.01.020","article-title":"SIDIAP database: electronic clinical. records in primary care as a source of information for epidemiologic research","volume":"138","author":"Bol\u00edbar","year":"2012","journal-title":"Med Clin (Barc)"},{"key":"10.1016\/j.aprim.2021.102171_bib0265","first-page":"135","article-title":"Construction and validation of a scoring system for the selection of high-quality data in a Spanish. population primary care database (SIDIAP)","volume":"19","author":"Garc\u00eda-Gil","year":"2011","journal-title":"Inform Prim Care"},{"key":"10.1016\/j.aprim.2021.102171_bib0270","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1093\/pan\/mpl013","article-title":"Matching as nonparametric. preprocessing for reducing model dependence in parametric causal inference","volume":"15","author":"Daniel","year":"2007","journal-title":"Polit Anal."},{"key":"10.1016\/j.aprim.2021.102171_bib0275","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1001\/jamapsychiatry.2017.0449","article-title":"Association of mental disorders and related medication use with risk for major osteoporotic fractures","volume":"74","author":"Bolton","year":"2017","journal-title":"JAMA Psychiatry."},{"key":"10.1016\/j.aprim.2021.102171_bib0280","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.euroneuro.2013.04.002","article-title":"Schizophrenia, antipsychotics and risk of hip fracture: a population-based analysis","volume":"23","author":"Sorensen","year":"2013","journal-title":"Eur Neuropsychopharmacol."},{"key":"10.1016\/j.aprim.2021.102171_bib0285","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/pst.433","article-title":"Optimal caliper widths for propensity-score matching when. estimating differences in means and differences in proportions in observational studies","volume":"10","author":"Austin","year":"2011","journal-title":"Pharm Stat."},{"key":"10.1016\/j.aprim.2021.102171_bib0290","doi-asserted-by":"crossref","first-page":"e1967","DOI":"10.1097\/MD.0000000000001967","article-title":"Bone mineral density in schizophrenia. An update of current meta-analysis and literature review under guideline of PRISMA","volume":"94","author":"Ping-Tao","year":"2015","journal-title":"Medicine (Baltimore)."},{"key":"10.1016\/j.aprim.2021.102171_bib0295","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/schbul\/22.3.447","article-title":"Accelerated osteoporosis in psychiatric patients: possible pathophysiological processes","volume":"22","author":"Halbreich","year":"1996","journal-title":"Schizophr Bull."},{"key":"10.1016\/j.aprim.2021.102171_bib0300","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1176\/appi.ajp.162.1.162","article-title":"Osteoporosis in patients with schizophrenia","volume":"162","author":"Hummer","year":"2005","journal-title":"Am J Psychiatry."},{"key":"10.1016\/j.aprim.2021.102171_bib0305","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2174\/157015908784533860","article-title":"Antipsychotics for the treatment of Behavioral and Psychological Symptoms of Dementia (BPSD)","volume":"6","author":"Liperoti","year":"2008","journal-title":"Curr Neuropharmacol."},{"key":"10.1016\/j.aprim.2021.102171_bib0310","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1080\/10401230500464687","article-title":"Bone mineral density in male schizophrenia patients: a review","volume":"18","author":"Meyer","year":"2006","journal-title":"Ann Clin Psychiatry."},{"key":"10.1016\/j.aprim.2021.102171_bib0315","first-page":"413","article-title":"Onset and course of the first schizophrenic episode","volume":"14","author":"Hafner","year":"1998","journal-title":"Kaohsiung J Med Sci."},{"key":"10.1016\/j.aprim.2021.102171_bib0320","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/00045391-200205000-00005","article-title":"Confounding by indication in epidemiologic studies of commonly used analgesics","volume":"9","author":"Signorello","year":"2002","journal-title":"Am J Ther."}],"container-title":["Atenci\u00f3n Primaria"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0212656721002055?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0212656721002055?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T13:01:36Z","timestamp":1759323696000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0212656721002055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S0212656721002055"],"URL":"https:\/\/doi.org\/10.1016\/j.aprim.2021.102171","relation":{},"ISSN":["0212-6567"],"issn-type":[{"type":"print","value":"0212-6567"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fracturas de cadera en pacientes tratados con f\u00e1rmacos antipsic\u00f3ticos. Estudio de cohortes hist\u00f3ricas en Catalu\u00f1a","name":"articletitle","label":"Article Title"},{"value":"Atenci\u00f3n Primaria","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aprim.2021.102171","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}],"article-number":"102171"}}