{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T03:20:54Z","timestamp":1794367254044,"version":"4.9.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aquatic Toxicology"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.aquatox.2010.01.008","type":"journal-article","created":{"date-parts":[[2010,2,5]],"date-time":"2010-02-05T09:18:35Z","timestamp":1265361515000},"page":"74-82","source":"Crossref","is-referenced-by-count":39,"title":["Induction of cytochrome P450 1 genes and stress response genes in developing zebrafish exposed to ultraviolet radiation"],"prefix":"10.1016","volume":"98","author":[{"given":"Lars","family":"Behrendt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria E.","family":"J\u00f6nsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared V.","family":"Goldstone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Stegeman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aquatox.2010.01.008_bib1","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1124\/mol.64.3.550","article-title":"Aspartate aminotransferase generates proagonists of the aryl hydrocarbon receptor","volume":"64","author":"Bittinger","year":"2003","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1093\/carcin\/bgm242","article-title":"Distinct effects of ultraviolet B light on antioxidant expression in undifferentiated and differentiated mouse keratinocytes","volume":"29","author":"Black","year":"2008","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.aquatox.2010.01.008_bib3","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/S0168-9525(97)01246-8","article-title":"Sunlight and the onset of skin cancer","volume":"13","author":"Brash","year":"1997","journal-title":"Trends Genet."},{"key":"10.1016\/j.aquatox.2010.01.008_bib4","doi-asserted-by":"crossref","first-page":"10124","DOI":"10.1073\/pnas.88.22.10124","article-title":"A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma","volume":"88","author":"Brash","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.aquatox.2010.01.008_bib5","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1562\/0031-8655(2003)077<0397:UNDDIT>2.0.CO;2","article-title":"Ultraviolet (280\u2013400nm)-induced DNA damage in the eggs and larvae of Calanus finmarchicus G. (Copepoda) and Atlantic cod (Gadus morhua)","volume":"77","author":"Browman","year":"2003","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib6","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1562\/0031-8655(2000)072<0327:UBREOA>2.0.CO;2","article-title":"Ultraviolet-B radiation effects on antioxidant status and survival in the zebrafish, Brachydanio rerio","volume":"72","author":"Charron","year":"2000","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib7","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/j.0906-6705.2004.00209.x","article-title":"Extracellular superoxide dismutase tissue distribution and the patterns of superoxide dismutase mRNA expression following ultraviolet irradiation on mouse skin","volume":"13","author":"Choung","year":"2004","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib8","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1021\/tx9000418","article-title":"Structural identification of Diindole agonists of the aryl hydrocarbon receptor derived from degradation of indole-3-pyruvic acid","volume":"22","author":"Chowdhury","year":"2009","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib9","unstructured":"Dahms, H.U., Lee, J.S., 2009. UV radiation in marine ectotherms: molecular effects and responses. Aquat. Toxicol, Epub December 4."},{"key":"10.1016\/j.aquatox.2010.01.008_bib10","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1093\/toxsci\/kfj065","article-title":"Sunlight generates multiple tryptophan photoproducts eliciting high efficacy CYP1A induction in chick hepatocytes and in vivo","volume":"90","author":"Diani-Moore","year":"2006","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.aquatox.2010.01.008_bib11","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jphotobiol.2007.07.002","article-title":"Photobiological effects of UVA and UVB light in zebrafish embryos: evidence for a competent photorepair system","volume":"88","author":"Dong","year":"2007","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.aquatox.2010.01.008_bib12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1089\/zeb.2006.9997","article-title":"Zebrafish in the wild: a review of natural history and new notes from the field","volume":"4","author":"Engeszer","year":"2007","journal-title":"Zebrafish"},{"key":"10.1016\/j.aquatox.2010.01.008_bib13","doi-asserted-by":"crossref","first-page":"9350","DOI":"10.1128\/MCB.25.21.9350-9359.2005","article-title":"Nuclear dynamics of PCNA in DNA replication and repair","volume":"25","author":"Essers","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib14","doi-asserted-by":"crossref","first-page":"8851","DOI":"10.1073\/pnas.0701764104","article-title":"Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation","volume":"104","author":"Fritsche","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.aquatox.2010.01.008_bib15","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/s004030050151","article-title":"Influence of UVA and UVB irradiation on hepatic and cutaneous P450 isoenzymes","volume":"289","author":"Goerz","year":"1996","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.aquatox.2010.01.008_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2307\/1266761","article-title":"Procedures for detecting outlying observations in samples","volume":"11","author":"Grubbs","year":"1969","journal-title":"Technometrics"},{"key":"10.1016\/j.aquatox.2010.01.008_bib17","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1039\/B700020K","article-title":"Effects of solar UV radiation on aquatic ecosystems and interactions with climate change","volume":"6","author":"H\u00e4der","year":"2007","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.aquatox.2010.01.008_bib18","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.aquatox.2003.11.001","article-title":"High sensitivity of northern pike larvae to UV-B but no UV-photoinduced toxicity of retene","volume":"66","author":"Hakkinen","year":"2004","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib19","first-page":"203","article-title":"High levels of p53 protein in UV-irradiated normal human skin","volume":"8","author":"Hall","year":"1993","journal-title":"Oncogene"},{"key":"10.1016\/j.aquatox.2010.01.008_bib20","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1751-1097.1979.tb07055.x","article-title":"Effect of ultraviolet irradiation on eggs and larvae on the northern anchovy, Engraulis mordax, and the Pacific mackerel, Scomber japonicus, during the embryonic stage","volume":"29","author":"Hunter","year":"1979","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib21","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S1011-1344(97)00071-7","article-title":"Regulation of copper\/zinc and manganese superoxide dismutase by UVB irradiation, oxidative stress and cytokines","volume":"40","author":"Isoherranen","year":"1997","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.aquatox.2010.01.008_bib22","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.cbi.2009.07.003","article-title":"The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish","volume":"181","author":"J\u00f6nsson","year":"2009","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.aquatox.2010.01.008_bib23","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1046\/j.1523-1747.2000.00876.x","article-title":"Ultraviolet-B exposure of human skin induces cytochromes P450 1A1 and 1B1","volume":"114","author":"Katiyar","year":"2000","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib24","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1046\/j.0022-202x.2001.01540.x","article-title":"In situ visualization of ultraviolet-light-induced DNA damage repair in locally irradiated human fibroblasts","volume":"117","author":"Katsumi","year":"2001","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib25","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/BF02634372","article-title":"Transient induction of cytochrome P450 1A1 mRNA by culture medium component in primary cultures of adult rat hepatocytes","volume":"29A","author":"Kocarek","year":"1993","journal-title":"In Vitro Cell Dev. Biol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib26","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1080\/019262390908380","article-title":"Analysis of p53 tumor suppressor gene, H-ras protooncogene and proliferating cell nuclear antigen (PCNA) in squamous cell carcinomas of HRA\/Skh mice following exposure to 8-methoxypsoralen (8-MOP) and UVA radiation (PUVA therapy)","volume":"33","author":"Lambertini","year":"2005","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib27","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.cbi.2009.09.017","article-title":"Responsiveness of a Xenopus laevis cell line to the aryl hydrocarbon receptor ligands 6-formylindolo[3,2-b]carbazole (FICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)","volume":"183","author":"Laub","year":"2010","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.aquatox.2010.01.008_bib28","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2DeltaDeltaCT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.aquatox.2010.01.008_bib29","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1046\/j.0022-202x.2001.01562.x","article-title":"Nucleotide excision repair genes are upregulated by low-dose artificial ultraviolet B: evidence of a photoprotective SOS response?","volume":"117","author":"Maeda","year":"2001","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib30","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1471-2199-9-102","article-title":"Characterization of housekeeping genes in zebrafish: male\u2013female differences and effects of tissue type, developmental stage and chemical treatment","volume":"9","author":"McCurley","year":"2008","journal-title":"BMC Mol. Biol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib31","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1039\/B700017K","article-title":"Changes in biologically-active ultraviolet radiation reaching the Earth's surface","volume":"6","author":"McKenzie","year":"2007","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.aquatox.2010.01.008_bib32","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1562\/0031-8655(2004)080<0587:EOUBEO>2.0.CO;2","article-title":"Effects of ultraviolet B exposure on the expression of proliferating cell nuclear antigen in murine skin","volume":"80","author":"Moore","year":"2004","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib33","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1093\/toxsci\/kfl126","article-title":"Effects of tryptophan photoproducts in the circadian timing system: searching for a physiological role for aryl hydrocarbon receptor","volume":"95","author":"Mukai","year":"2007","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.aquatox.2010.01.008_bib34","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1158\/1940-6207.CAPR-09-0125","article-title":"UVR exposure sensitizes keratinocytes to DNA adduct formation","volume":"2","author":"Nair","year":"2009","journal-title":"Cancer Prev. Res. (Phila Pa)"},{"key":"10.1016\/j.aquatox.2010.01.008_bib35","series-title":"Tropospheric Ultraviolet & Visible Radiation Model","author":"(NCAR\/ACD) National Center for Atmospheric Research","year":"2009"},{"key":"10.1016\/j.aquatox.2010.01.008_bib36","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1021\/tx900043s","article-title":"d-amino acid oxidase generates agonists of the aryl hydrocarbon receptor from d-tryptophan","volume":"22","author":"Nguyen","year":"2009","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib37","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1093\/toxsci\/kfi154","article-title":"Identification of the tryptophan photoproduct 6-formylindolo[3,2-b]carbazole, in cell culture medium, as a factor that controls the background aryl hydrocarbon receptor activity","volume":"85","author":"Oberg","year":"2005","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.aquatox.2010.01.008_bib38","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/1523-1747.ep12478037","article-title":"Effects of single-dose ultraviolet radiation on skin superoxide dismutase, catalase, and xanthine oxidase in hairless mice","volume":"95","author":"Pence","year":"1990","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.aquatox.2010.01.008_bib39","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/1011-1344(95)07131-K","article-title":"Chronic UVB irradiation induces superoxide dismutase activity in human epidermis in vivo","volume":"30","author":"Punnonen","year":"1995","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.aquatox.2010.01.008_bib40","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1098\/rstb.2005.1783","article-title":"Stratospheric ozone depletion","volume":"361","author":"Rowland","year":"2006","journal-title":"Philos. Trans. R. Soc. Lond. B: Biol. Sci."},{"key":"10.1016\/j.aquatox.2010.01.008_bib41","doi-asserted-by":"crossref","first-page":"11919","DOI":"10.1016\/S0021-9258(19)38488-1","article-title":"Superoxide dismutase undergoes proteolysis and fragmentation following oxidative modification and inactivation","volume":"265","author":"Salo","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.aquatox.2010.01.008_bib42","doi-asserted-by":"crossref","first-page":"3363","DOI":"10.1073\/pnas.71.9.3363","article-title":"The wavelengths in sunlight effective in producing skin cancer: a theoretical analysis","volume":"71","author":"Setlow","year":"1974","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.aquatox.2010.01.008_bib43","doi-asserted-by":"crossref","first-page":"L12610","DOI":"10.1029\/2007GL029823","article-title":"High penetration of ultraviolet radiation in the south east Pacific waters","volume":"34","author":"Tedetti","year":"2007","journal-title":"Geophys. Res. Lett."},{"key":"10.1016\/j.aquatox.2010.01.008_bib44","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S1011-1344(00)00005-1","article-title":"Oxidative stress and defence mechanisms of the freshwater cladoceran Daphnia longispina exposed to UV radiation","volume":"54","author":"Vega","year":"2000","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.aquatox.2010.01.008_bib45","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1897\/02-569","article-title":"Photoinduced lethal and sublethal toxicity of retene, a polycyclic aromatic hydrocarbon derived from resin acid, to coregonid larvae","volume":"22","author":"Vehniainen","year":"2003","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.aquatox.2010.01.008_bib46","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1006\/abbi.2000.2037","article-title":"Regulation of CYP1A1 transcription via the metabolism of the tryptophan-derived 6-formylindolo[3,2-b]carbazole","volume":"383","author":"Wei","year":"2000","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.aquatox.2010.01.008_bib47","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0009-2797(98)00118-5","article-title":"UV-induced CYP1A1 gene expression in human cells is mediated by tryptophan","volume":"118","author":"Wei","year":"1999","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.aquatox.2010.01.008_bib48","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1074\/jbc.M808321200","article-title":"The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P4501 substrate 6-formylindolo[3,2-b]carbazole is present in humans","volume":"284","author":"Wincent","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.aquatox.2010.01.008_bib49","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1046\/j.1467-2960.2001.00048.x","article-title":"The implications of solar UV radiation exposure for fish and fisheries","volume":"2","author":"Zagarese","year":"2001","journal-title":"Fish Fisheries"},{"key":"10.1016\/j.aquatox.2010.01.008_bib50","doi-asserted-by":"crossref","first-page":"13748","DOI":"10.1016\/S0021-9258(17)36709-1","article-title":"DNA polymerase delta is involved in the cellular response to UV damage in human cells","volume":"269","author":"Zeng","year":"1994","journal-title":"J. Biol. Chem."}],"container-title":["Aquatic Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X10000202?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X10000202?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T09:30:41Z","timestamp":1634895041000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166445X10000202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S0166445X10000202"],"URL":"https:\/\/doi.org\/10.1016\/j.aquatox.2010.01.008","relation":{},"ISSN":["0166-445X"],"issn-type":[{"value":"0166-445X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}