{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T17:10:49Z","timestamp":1791133849136,"version":"4.1.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aquatic Toxicology"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.aquatox.2012.06.003","type":"journal-article","created":{"date-parts":[[2012,6,26]],"date-time":"2012-06-26T11:58:24Z","timestamp":1340711904000},"page":"163-171","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Absorption, distribution, and elimination of graded oral doses of methylmercury in juvenile white sturgeon"],"prefix":"10.1016","volume":"122-123","author":[{"given":"Susie Shih-Yin","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders Bjerring","family":"Strathe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James G.","family":"Fadel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinpin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsung-Yun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silas S.O.","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aquatox.2012.06.003_bib0005","first-page":"135","article-title":"Hematological features of young sturgeons","volume":"4","author":"Alyakrinskyaya","year":"1984","journal-title":"Voprosy Ikhtiologii"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0010","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.aquatox.2007.05.008","article-title":"Accumulation and elimination of methylmercury in Atlantic cod (Gadus morhua L.) following dietary exposure","volume":"83","author":"Amlund","year":"2007","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0015","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0149-7634(05)80217-9","article-title":"Mercury neurotoxicity: mechanisms of blood-brain barrier transport","volume":"14","author":"Aschner","year":"1990","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0020","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0006-8993(88)90581-1","article-title":"Uptake of methylmercury in the rat brain: effects of amino acids","volume":"462","author":"Aschner","year":"1988","journal-title":"Brain Research"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0025","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0166-445X(90)90063-U","article-title":"Pharmacokinetic modeling in aquatic animals I. Model and concepts","volume":"17","author":"Barron","year":"1990","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0030","series-title":"The Textbook of Modern Toxicology","first-page":"79","article-title":"Absorption and distribution of toxicants","author":"Baynes","year":"2010"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0035","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0166-445X(03)00104-8","article-title":"Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behavior in Atlantic salmon (Salmo salar) parr","volume":"65","author":"Berntssen","year":"2003","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0040","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/BF00342318","article-title":"Fundamental roles of biological barriers in mercury accumulation and transfer in freshwater ecosystems","volume":"56","author":"Boudou","year":"1991","journal-title":"Water, Air, and Soil Pollution"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0045","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1021\/es60085a012","article-title":"Studies on uptake and loss of methylmercurr-203 by blue-gills (Lepomis macrochirus Raf.)","volume":"7","author":"Burrows","year":"1973","journal-title":"Environmental Science and Technology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0050","series-title":"The Biogeochemistry of Mercury in the Environment","first-page":"433","article-title":"The chemistry of mercury in biological systems","author":"Carty","year":"1979"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0055","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1046\/j.1439-0426.2002.00362.x","article-title":"Physiology of sturgeon: effects of hypoxia and hypercapnia","volume":"18","author":"Cech","year":"2002","journal-title":"Journal of Applied Ichthyology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0060","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1002\/ajim.20476","article-title":"Mechanisms of mercury disposition in the body","volume":"50","author":"Clarkson","year":"2007","journal-title":"American Journal of Industrial Medicine"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0065","unstructured":"CNDDB (California Natural Diversity Database), 2009. Department of Fish and Game, Biographic Data Branch. Special animals (883 taxa), July 2009. http:\/\/www.dfg.ca.gov\/biogeodata\/cnddb\/pdfs\/SPAnimals.pdf."},{"key":"10.1016\/j.aquatox.2012.06.003_bib0070","unstructured":"Davis, J., Hunt, J., Greenfield, B.K., Fairey, R., Sigala, M., Crane, D., Regalado, K., Bonnema, A., 2006. Contamination Concentrations in Fish from San Francisco Bay, 2003. SFEI. 52 pp. http:\/\/www.sfei.org\/sites\/default\/files\/No432_RMPFishReport_complete.pdf"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0075","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1023\/A:1007803307617","article-title":"A new technique of feeding, repeated sampling of blood and continuous collection of urine in white sturgeon","volume":"22","author":"Deng","year":"2000","journal-title":"Fish Physiology and Biochemistry"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0080","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0013-9351(02)00025-7","article-title":"Histopathological evidence of inorganic mercury and methyl mercury toxicity in the arctic charr (Salvelinus alpinus)","volume":"90","author":"de Oliveira Ribeiro","year":"2002","journal-title":"Environmental Research"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0085","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1021\/es980242n","article-title":"Distribution kinetics of dietary methylmercury in the Artic Charr (Salvelinus alpinus)","volume":"33","author":"de Oliveira Ribeiro","year":"1999","journal-title":"Environmental Science and Technology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0090","first-page":"498","article-title":"Occurrence and transport of total mercury and methyl mercury in the Sacramento River Basin, California","volume":"50","author":"Domagalski","year":"1998","journal-title":"Journal of Geochemical Exploration"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0095","doi-asserted-by":"crossref","first-page":"4390","DOI":"10.1021\/es034252m","article-title":"Effects of dietary methylmercury on reproductive endocrinology of fathead minnows","volume":"37","author":"Drevnick","year":"2003","journal-title":"Environmental Science and Technology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0100","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0166-445X(85)90039-6","article-title":"In vivo absorption of l-leucine by the intestine of the toadfish Opsanus tau\u2014the effect of several heavy metal compounds","volume":"7","author":"Farmanfarmaian","year":"1985","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0105","series-title":"Global and Regional Mercury Cycles: Sources, Fluxes and Mass Balances","article-title":"The global mercury cycle: oceanic and anthropogenic aspects","author":"Fitzgerald","year":"1996"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0110","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/0024-3205(74)90511-6","article-title":"Mercury incorporation by mature and immature red blood cells","volume":"15","author":"Garrett","year":"1974","journal-title":"Life Sciences"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0115","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0300-483X(75)90121-3","article-title":"The erythrocyte transport and transfer of methyl-mercury to the tissues of the rainbow trout (Salmo gairdneri)","volume":"5","author":"Giblin","year":"1975","journal-title":"Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0120","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0044-8486(03)00264-3","article-title":"Glycemic responses in white sturgeon after oral administration of graded doses of d-glucose","volume":"224","author":"Gisbert","year":"2003","journal-title":"Aquaculture"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0125","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.aquatox.2004.04.005","article-title":"Effects of dietary methylmercury on juvenile Sacramento blackfish bioenergetics","volume":"69","author":"Houck","year":"2004","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0130","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.aquatox.2011.11.005","article-title":"Selenocompounds in juvenile white sturgeon: absorption, disposition, and elimination of selenium using Bayesian hierarchical modeling","volume":"109","author":"Huang","year":"2012","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0135","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.aquatox.2011.12.009","article-title":"Selenocompounds in juvenile white sturgeon: evaluating blood, tissue, and urine selenium concentrations after a single oral dose","volume":"109","author":"Huang","year":"2012","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0140","first-page":"R761","article-title":"Methylmercury transport across the blood\u2013brain barrier by an amino acid carrier","volume":"262","author":"Kerper","year":"1992","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0145","doi-asserted-by":"crossref","first-page":"4281","DOI":"10.1242\/jeb.204.24.4281","article-title":"Juvenile sturgeon exhibit reduced physiological responses to exercise","volume":"204","author":"Kieffer","year":"2001","journal-title":"Journal of Experimental Biology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0150","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0147-6513(89)90046-8","article-title":"Toxic effects of mercurials on thyroid function of the catfish, Clarias batrachus (L)","volume":"17","author":"Kirubagaran","year":"1989","journal-title":"Ecotoxicology and Environment Safety"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0155","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1046\/j.1439-0426.2002.00381.x","article-title":"Assessment of bioaccumulated metal and organochlorine compounds in relation to physiological biomarkers in Kootenai River white sturgeon","volume":"18","author":"Kruse","year":"2002","journal-title":"Journal of Applied Ichthyology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0160","series-title":"Introduction to Environmental Toxicology: Impacts of Chemicals Upon Ecological Systems","author":"Landis","year":"2004"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0165","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.aquatox.2011.06.013","article-title":"Effects of dietary methylmercury on growth performance and tissue burden in juvenile green (Acipenser medirostris) and white sturgeon (A. transmontanus)","volume":"104","author":"Lee","year":"2011","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0170","first-page":"479","article-title":"Contaminants in white sturgeon (Acipenser transmontanus) from the upper Fraser River, British Columbia, Canada","volume":"16","author":"MacDonald","year":"1997","journal-title":"Environmental Toxicology and Chemistry"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0175","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1139\/f76-324","article-title":"Long-term effects of methylmercuric chloride on three generations of brook trout (Salvelinus fontinalis): toxicity, accumulation, distribution, and elimination","volume":"33","author":"McKim","year":"1976","journal-title":"Journal of the Fisheries Research Board of Canada"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0180","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/BF00224801","article-title":"Evaluation of the critical body burden concept based on inorganic and organic mercury toxicity to rainbow trout (Oncorhynchus mykiss)","volume":"26","author":"Niimi","year":"1994","journal-title":"Archives of Environment Contamination and Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0185","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1139\/f78-068","article-title":"Tissue uptake, subcellular distribution and metabolism of 14CH3HgCl and CH3203HgCl by rainbow trout, Salmo gairdneri","volume":"35","author":"Olson","year":"1978","journal-title":"Journal of the Fisheries Research Board of Canada"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0190","first-page":"1700","article-title":"Chemical nature of a methylmercury complex with a low molecular weight in the liver cytosol of rats exposed to methylmercury chloride","volume":"30","author":"Omata","year":"1978","journal-title":"Biochemical Pharmacology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0195","series-title":"Pollution and Physiology of Marine Organisms","first-page":"101","article-title":"Methylmercury and inorganic mercury: uptake, distribution, and effect on osmoregulatory mechanisms in fishes","author":"Renfro","year":"1974"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0200","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0272-0590(89)90058-4","article-title":"Pharmacokinetics of methylmercury in the blood of monkeys (Macaca fascicularis)","volume":"12","author":"Rice","year":"1989","journal-title":"Fundamental and Applied Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0205","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0166-445X(82)90016-9","article-title":"Dynamics of dietary methylmercury in rainbow trout, Salmo gairdneri","volume":"2","author":"Rodgers","year":"1982","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0210","first-page":"161","article-title":"Distribution of inorganic mercury in Sacramento River water and suspended colloidal sediment material","volume":"40","author":"Roth","year":"2000","journal-title":"Archives of Environment Contamination and Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0215","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0166-445X(99)00044-2","article-title":"The teratogenic effects of methylmercury on early development of the zebrafish","volume":"48","author":"Samson","year":"2000","journal-title":"Aquatic Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0220","doi-asserted-by":"crossref","first-page":"3053","DOI":"10.1897\/05-641R.1","article-title":"Effects of dietary methylmercury on reproductive behavior of fathead minnows","volume":"25","author":"Sandheinrich","year":"2006","journal-title":"Environmental Toxicology and Chemistry"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0225","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/BF02834073","article-title":"Inhibition of RNA and protein synthesis in isolated cerebellar cells by in vitro and in vivo methyl mercury","volume":"3","author":"Sarafian","year":"1985","journal-title":"Neurochemical Pathology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0230","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1002\/etc.5620160518","article-title":"Methyl mercury toxicokinetics in channel catfish (Ictalurus punctatus) and largemouth bass (Micropterus salmoides) after intravascular administration","volume":"16","author":"Schultz","year":"1997","journal-title":"Environmental Toxicology and Chemistry"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0235","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1042\/BJ20041973","article-title":"Hepatically-derived selenoprotein P is a key factor for kidney but not for brain selenium supply","volume":"386","author":"Schweizer","year":"2005","journal-title":"Biochemical Journal"},{"issue":"12b","key":"10.1016\/j.aquatox.2012.06.003_bib0240","first-page":"1482","article-title":"Behavioural abnormalities of tench (Tinca tinca L., 1758) on exposure to mercury, cadmium and lead","volume":"13","author":"Shah","year":"2004","journal-title":"Fresenius Environmental Bulletin"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0245","unstructured":"Slotton, D.G., Ayers, S.M., Suchanek, T.H., Weyand, R.D., Liston, A.M., Asher, C., Nelson, D.C., Johnson, B., 2002. The effects of wetland restoration on the production and bioaccumulation of methylmercury in the Sacramento-San Joaquin Delta, California. CALFED Bay-Delta Agency. 49 pp. http:\/\/loer.tamug.edu\/calfed\/Report\/DraftFinal\/UCD_Delta_Report.pdf."},{"key":"10.1016\/j.aquatox.2012.06.003_bib0250","series-title":"Aquatic Chemistry \u2013 Chemical Equilibria and Rates in Natural Waters","author":"Stumm","year":"1996"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0255","first-page":"436","article-title":"Imputation of data values that are less than a detection limit","volume":"1","author":"Succop","year":"2004","journal-title":"Journal of Occupational and Environmental Health"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0265","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/0041-008X(82)90106-5","article-title":"Effects of coadministered low molecular weight thiol compounds on short term distribution of methylmercury in the rat","volume":"62","author":"Thomas","year":"1982","journal-title":"Toxicology and Applied Pharmacology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0270","series-title":"International Seminar on Restoration of Damaged Lagoon Environment","article-title":"The immigration of an Asian bivalve Potamocorbula into San Francisco Bay and the subsequent environmental change","author":"Thompson","year":"2004"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0275","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/20016491089226","article-title":"Mercury in the aquatic environment: a review of factors affecting methylation","volume":"31","author":"Ullrich","year":"2001","journal-title":"Critical Reviews in Environment Science and Technology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0280","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00244-004-0159-0","article-title":"Mercury concentrations in gonad, liver, and muscle of white sturgeon Acipenser transmontanus in the lower Columbia River","volume":"50","author":"Webb","year":"2006","journal-title":"Archives of Environment Contamination and Toxicology"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0285","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1139\/f95-809","article-title":"Swimming performance and predator avoidance by mummichog (Fundulus heteroclitus) larvae after embryonic or larval exposure to methylmercury","volume":"52","author":"Weis","year":"1995","journal-title":"Canadian Journal of Fisheries and Aquatic Sciences"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0290","series-title":"Mercury \u2013 Environmental Aspects","year":"1989"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0295","series-title":"Environmental Contaminants in Wildlife, Interpreting Tissue Concentration","first-page":"297","article-title":"Toxicological significance of mercury in freshwater fish","author":"Wiener","year":"1996"},{"key":"10.1016\/j.aquatox.2012.06.003_bib0300","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/1043-6618(95)80018-2","article-title":"Discrimination of transport systems for methylmercury-cysteine uptake in rat erythrocytes by inhibitors and other factors","volume":"31","author":"Wu","year":"1995","journal-title":"Pharmacological Research"}],"container-title":["Aquatic Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X12001968?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X12001968?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T14:36:03Z","timestamp":1642602963000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166445X12001968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":59,"alternative-id":["S0166445X12001968"],"URL":"https:\/\/doi.org\/10.1016\/j.aquatox.2012.06.003","relation":{},"ISSN":["0166-445X"],"issn-type":[{"value":"0166-445X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}