{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:33:45Z","timestamp":1790696025290,"version":"4.1.0"},"reference-count":134,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Aquatic Toxicology"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.aquatox.2017.01.004","type":"journal-article","created":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T15:32:02Z","timestamp":1484494322000},"page":"61-77","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":66,"special_numbering":"C","title":["Proteome response of fish under multiple stress exposure: Effects of pesticide mixtures and temperature increase"],"prefix":"10.1016","volume":"184","author":[{"given":"Allison","family":"Gandar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Laffaille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Marty-Gasset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Viala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Molette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9verine","family":"Jean","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aquatox.2017.01.004_bib0005","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1289\/ehp.99107593","article-title":"Arsenic: health effects, mechanisms of actions, and research issues","volume":"107","author":"Abernathy","year":"1999","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0010","series-title":"Agriculture, Agri-Food and Forest Data. French Ministry of Agriculture, Agro-food and Forest Report","author":"Alim\u2019agri","year":"2012"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0015","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1074\/jbc.M411221200","article-title":"15-Hydroxyprostaglandin dehydrogenase is downregulated in colorectal cancer","volume":"280","author":"Backlund","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0020","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0378-1119(02)00687-X","article-title":"Heat shock protein genes and their functional significance in fish","volume":"295","author":"Basu","year":"2002","journal-title":"Gene"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0025","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0048-9697(99)00536-7","article-title":"Occurrence of sulfonylurea, sulfonamide, imidazolinone, and other herbicides in rivers, reservoirs and ground water in the Midwestern United States, 1998","volume":"248","author":"Battaglin","year":"2000","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/toxsci\/kfl157","article-title":"Toxicoproteomics\u2014the next step in the evolution of environmental biomarkers?","volume":"95","author":"Benninghoff","year":"2007","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0035","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.aquatox.2010.09.019","article-title":"Proteomic analysis of a model fish species exposed to individual pesticides and a binary mixture","volume":"101","author":"Biales","year":"2011","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0040","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jhazmat.2011.09.012","article-title":"Occurrence of metolachlor and trifluralin losses in the Save river agricultural catchment during floods","volume":"196","author":"Boithias","year":"2011","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0045","unstructured":"Bonnefoy, N., 2012. Information report on behalf of the joint mission of information on pesticides and their impact on health and the environment. Report of the French Senate (in French). Paris, France"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0050","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00300-006-0165-y","article-title":"Temperature-dependent energy allocation to growth in Antarctic and boreal eelpout (Zoarcidae)","volume":"30","author":"Brodte","year":"2006","journal-title":"Polar Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0055","unstructured":"Butault, J.-P., Dedryver, C.-A., Gary, C., Guichard, L., Jacquet, F., Meynard, J.-M., Nicot, P., Pitra, M., Reau, R., Sauphanor, B., Savini, I., Volay, T., 2010. Ecophyto R&D: What ways to reduce the use of pesticides? Summary of the study report (in French). France"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0060","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1016\/j.biocel.2013.08.005","article-title":"Regulation of 15-hydroxyprostaglandin dehydrogenase expression in hepatocellular carcinoma","volume":"45","author":"Castro-S\u00e1nchez","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0065","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.aquatox.2009.06.014","article-title":"Changes in the protein expression profiles of the Hepa-T1 cell line when exposed to Cu2+","volume":"94","author":"Chen","year":"2009","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0070","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.fsi.2011.01.003","article-title":"Proteomic analysis of methyl parathion-responsive proteins in Sparus latus liver","volume":"30","author":"Chen","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0075","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1096\/fj.03-1204fje","article-title":"Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A","volume":"18","author":"Chen","year":"2004","journal-title":"FASEB J."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0080","series-title":"Bone Cancer: Primary Bone Cancers and Bone Metastases","first-page":"365","article-title":"Zebrafish models for studying bone cancers: mutants, transgenic fish and embryos","author":"Cleten-Jansen","year":"2014"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0085","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/2190-4715-23-22","article-title":"Predicting the aquatic toxicity of commercial pesticide mixtures","volume":"23","author":"Coors","year":"2011","journal-title":"Environ. Sci. Eur."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0090","unstructured":"Croze, O., Blot, E., Delmouly, L., 2007. Evolution of the water temperature of the Garonne River between 1977 and 2005 (in French)."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0095","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1007\/s10695-013-9879-2","article-title":"Effect of heat stress and recovery on viability, oxidative damage, and heat shock protein expression in hepatic cells of grass carp (Ctenopharyngodon idellus)","volume":"40","author":"Cui","year":"2014","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0100","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.fsi.2012.03.029","article-title":"Molecular characterization, immune responses and DNA protection activity of rock bream (Oplegnathus fasciatus), peroxiredoxin 6 (Prx6)","volume":"33","author":"De Zoysa","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0105","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.aquatox.2008.03.011","article-title":"Herbicide effects on freshwater benthic diatoms: induction of nucleus alterations and silica cell wall abnormalities","volume":"88","author":"Debenest","year":"2008","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0110","series-title":"Characterization of the Impact of Agricultural Pollution on Benthic Diatoms. Ph.D. Thesis","author":"Debenest","year":"2007"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0115","series-title":"Biochemistry and Molecular Biology of Fishes","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S1873-0140(05)80006-2","article-title":"Approaches in proteomics and genomics for eco-toxicology","author":"Denslow","year":"2005"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0120","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.chemosphere.2014.01.079","article-title":"The impact of temperature stress and pesticide exposure on mortality and disease susceptibility of endangered Pacific salmon","volume":"108","author":"Dietrich","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0125","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1021\/pr100650z","article-title":"Proteomic response to sublethal cadmium exposure in a sentinel fish species, Cottus gobio","volume":"10","author":"Dorts","year":"2011","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0130","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1016\/j.fsi.2012.08.013","article-title":"Physiological and proteomic responses to single and repeated hypoxia in juvenile Eurasian perch under domestication\u2014clues to physiological acclimation and humoral immune modulations","volume":"33","author":"Douxfils","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0135","first-page":"321","article-title":"Impacts of mixtures of herbicides on molecular and physiological responses of the European flounder Platichthys flesus","volume":"152","author":"Evrard","year":"2010","journal-title":"Comp. Biochem. Physiol.: C Toxicol. Pharmacol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0140","first-page":"220","article-title":"Comparative proteomics of copper exposure and toxicity in rainbow trout, common carp and gibel carp","volume":"7","author":"Eyckmans","year":"2012","journal-title":"Comp. Biochem. Physiol. D: Genom. Proteom."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0145","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.aquatox.2006.11.013","article-title":"Combined effects of herbicides on biomarkers reflecting immune-endocrine interactions in goldfish. Immune and antioxidant effects","volume":"81","author":"Fatima","year":"2007","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0150","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1038\/nrc3979","article-title":"Imaging innate immune responses at tumour initiation: new insights from fish and flies","volume":"15","author":"Feng","year":"2015","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0155","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.aquatox.2013.07.001","article-title":"Comparative antioxidant status in freshwater fish Carassius auratus exposed to six current-use brominated flame retardants: a combined experimental and theoretical study","volume":"140\u2013141","author":"Feng","year":"2013","journal-title":"Aquat. Toxicol."},{"issue":"2","key":"10.1016\/j.aquatox.2017.01.004_bib0160","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jtherbio.2004.09.004","article-title":"Temperature tolerance in the goldfish, Carassius auratus","volume":"30","author":"Ford","year":"2005","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0165","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.jhep.2013.04.031","article-title":"Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis","volume":"59","author":"Frau","year":"2013","journal-title":"J. Hepatol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0170","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.semcdb.2011.08.009","article-title":"14-3-3 Proteins: diverse functions in cell proliferation and cancer progression","volume":"22","author":"Freeman","year":"2011","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0175","first-page":"586","article-title":"The relation of temperature to oxygen consumption in the goldfish","volume":"96","author":"Fry","year":"1946","journal-title":"Anat. Rec."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0180","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.bbrc.2011.09.067","article-title":"Senescence marker protein 30 (SMP30)\/regucalcin (RGN) expression decreases with aging, acute liver injuries and tumors in zebrafish","volume":"414","author":"Fujisawa","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0185","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/ps.1000","article-title":"A risk assessment of atrazine use in California: human health and ecological aspects","volume":"61","author":"Gammon","year":"2005","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0190","first-page":"3323","article-title":"Multistress effects on behavior and physiology of Carassius auratus","volume":"24","author":"Gandar","year":"2016","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0195","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.semcdb.2011.09.008","article-title":"14-3-3 Proteins as signaling integration points for cell cycle control and apoptosis","volume":"22","author":"Gardino","year":"2011","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0200","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0048-9697(98)00326-X","article-title":"Spatial and temporal variations of herbicide (triazines and phenylureas) concentrations in the catchment basin of the Marne river (France)","volume":"224","author":"Garmouma","year":"1998","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0205","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S0160-4120(01)00031-9","article-title":"Impacts of atrazine in aquatic ecosystems","volume":"26","author":"Graymore","year":"2001","journal-title":"Environ. Int."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0210","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.chemosphere.2013.01.056","article-title":"Mechanistic toxicity study of perfluorooctanoic acid in zebrafish suggests mitochondrial dysfunction to play a key role in PFOA toxicity","volume":"91","author":"Hagenaars","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0215","doi-asserted-by":"crossref","first-page":"4490","DOI":"10.1242\/jeb.02532","article-title":"Sequence of Atlantic cod (Gadus morhua) GLUT4 GLUT2 and GPDH: developmental stage expression, tissue expression and relationship to starvation-induced changes in blood glucose","volume":"209","author":"Hall","year":"2006","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0220","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1126\/science.279.5350.509","article-title":"Rho GTPases and the actin cytoskeleton","volume":"279","author":"Hall","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0225","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1289\/ehp.8051","article-title":"Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?","volume":"114","author":"Hayes","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0230","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1080\/20014091111695","article-title":"A review of the effects of multiple stressors on aquatic organisms and analysis of uncertainty factors for use in risk assessment","volume":"31","author":"Heugens","year":"2001","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0235","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1152\/physrev.00037.2007","article-title":"Physiology of cell volume regulation in vertebrates","volume":"89","author":"Hoffmann","year":"2009","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0240","series-title":"Climate Change 2014: Synthesis Report. Contribution of Working Groups I, II and III to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change","author":"IPCC","year":"2014"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0245","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.chemosphere.2009.11.044","article-title":"Oxidative stress response and gene expression with atrazine exposure in adult female zebrafish (Danio rerio)","volume":"78","author":"Jin","year":"2010","journal-title":"Chemosphere"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0250","article-title":"Zebrafish as a model to study the role of DNA methylation in environmental toxicology","volume":"22","author":"Kamstra","year":"2014","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0255","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.toxicon.2011.03.018","article-title":"Toxins and stress in fish: proteomic analyses and response network","volume":"57","author":"Karim","year":"2011","journal-title":"Toxicon"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0260","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1080\/15287394.2011.550559","article-title":"Integrative environmental genomics of cod (Gadus morhua): the proteomics approach","volume":"74","author":"Karlsen","year":"2011","journal-title":"J. Toxicol. Environ. Health Part A"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0265","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1469-185X.2008.00073.x","article-title":"Animal performance and stress: responses and tolerance limits at different levels of biological organisation","volume":"84","author":"Kassahn","year":"2009","journal-title":"Biol. Rev."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0270","series-title":"Freshwater Fish Species in France (in French)","author":"Keith","year":"2011"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0275","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1016\/j.ecoenv.2009.04.018","article-title":"Proteomic studies in zebrafish liver cells exposed to the brominated flame retardants HBCD and TBBPA","volume":"72","author":"Kling","year":"2009","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0280","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.ecoenv.2007.12.010","article-title":"Gender-specific proteomic responses in zebrafish liver following exposure to a selected mixture of brominated flame retardants","volume":"71","author":"Kling","year":"2008","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0285","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/j.1749-6632.2012.06575.x","article-title":"Zebrafish xenografts as a tool for in vivo studies on human cancer","volume":"1266","author":"Konantz","year":"2012","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0290","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0065-2571(66)90027-6","article-title":"The regulation of the release of ketone bodies by the liver","volume":"4","author":"Krebs","year":"1966","journal-title":"Adv. Enzyme Regul."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0295","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0048-9697(98)00155-7","article-title":"Pesticides in stream water within an agricultural catchment in Southern Sweden, 1990\u20131996","volume":"216","author":"Kreuger","year":"1998","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0300","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.fsi.2009.03.005","article-title":"Effects of serum on phagocytic activity and proteomic analysis of tilapia (Oreochromis mossambicus) serum after acute osmotic stress","volume":"26","author":"Kumar","year":"2009","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0305","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.aquatox.2013.10.022","article-title":"Elevated temperatures increase the toxicity of pesticide mixtures to juvenile coho salmon","volume":"146","author":"Laetz","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0310","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.etap.2014.03.007","article-title":"Two-dimensional proteomic analysis of gonads of air-breathing catfish, Clarias batrachus after the exposure of endosulfan and malathion","volume":"37","author":"Laldinsangi","year":"2014","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0315","doi-asserted-by":"crossref","first-page":"3763","DOI":"10.1016\/j.scitotenv.2010.01.043","article-title":"Interactions between toxic chemicals and natural environmental factors\u2014a meta-analysis and case studies","volume":"408","author":"Laskowski","year":"2010","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0320","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1073\/pnas.1115528109","article-title":"14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma","volume":"109","author":"Lee","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0325","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1086\/383509","article-title":"Freeze resistance in rainbow smelt (Osmerus mordax): seasonal pattern of glycerol and antifreeze protein levels and liver enzyme activity associated with glycerol production","volume":"77","author":"Lewis","year":"2010","journal-title":"Physiol. Biochem. Zool."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0330","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.aquatox.2013.10.024","article-title":"NMR-based metabolomics approach to study the toxicity of lambda-cyhalothrin to goldfish (Carassius auratus)","volume":"146","author":"Li","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0335","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.etap.2008.10.004","article-title":"Proteomic changes in response to acute cadmium toxicity in gill tissue of Paralichthys olivaceus","volume":"27","author":"Ling","year":"2009","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0340","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/j.fsi.2012.03.002","article-title":"Cloning and functional characterisation of a peroxiredoxin 1 (NKEF A) cDNA from Atlantic salmon (Salmo salar) and its expression in fish infected with Neoparamoeba perurans","volume":"32","author":"Loo","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0345","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1006\/jsbi.2001.4386","article-title":"Review: postchaperonin tubulin folding cofactors and their role in microtubule dynamics","volume":"135","author":"Lopez-Fanarraga","year":"2001","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0350","first-page":"175","article-title":"Adaptive response to oxidative stress: bacteria, fungi, plants and animals","volume":"153","author":"Lushchak","year":"2011","journal-title":"Comp. Biochem. Physiol. C: Toxicol. Pharmacol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0355","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.plipres.2007.03.003","article-title":"Comparative genomics and evolution of eukaryotic phospholipid biosynthesis","volume":"46","author":"Lykidis","year":"2007","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0360","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s10126-005-0099-3","article-title":"Molecular identification and expression of differentially regulated genes of the European flounder Platichthys flesus, submitted to pesticide exposure","volume":"8","author":"Marchand","year":"2006","journal-title":"Mar. Biotechnol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0365","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.bbapap.2009.10.004","article-title":"The logic of the hepatic methionine metabolic cycle","volume":"1804","author":"Martinov","year":"2010","journal-title":"Biochim. Biophys. Acta\u2014Proteins Proteom."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0370","doi-asserted-by":"crossref","first-page":"4147","DOI":"10.1021\/pr3002468","article-title":"Hepatic protein expression networks associated with masculinization in the female fathead minnow (Pimephales promelas)","volume":"11","author":"Martyniuk","year":"2012","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0375","doi-asserted-by":"crossref","first-page":"45193","DOI":"10.1074\/jbc.M105971200","article-title":"14-3-3 proteins mediate an essential anti-apoptotic signal","volume":"276","author":"Masters","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0380","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ecoenv.2013.03.026","article-title":"Effects of the herbicide atrazine in neotropical catfish (Rhamdia quelen)","volume":"93","author":"Mela","year":"2013","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"6","key":"10.1016\/j.aquatox.2017.01.004_bib0385","doi-asserted-by":"crossref","first-page":"4992","DOI":"10.1007\/s11356-014-3662-5","article-title":"Toxicities of 48 pharmaceuticals and their freshwater and marine environmental assessment in northwestern France","volume":"23","author":"Minguez","year":"2016","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0390","doi-asserted-by":"crossref","first-page":"R39","DOI":"10.1172\/JCI6460","article-title":"Alpha-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy","volume":"103","author":"Mogensen","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0395","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1023\/A:1008924418720","article-title":"Cortisol in teleosts: dynamics, mechanisms of action, and metabolic regulation","volume":"9","author":"Mommsen","year":"1999","journal-title":"Rev. Fish Biol. Fish."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0400","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/BF00688619","article-title":"Starvation and the activities of glycolytic and gluconeogenic enzymes in skeletal muscles and liver of the plaice, Pleuronectes platessa","volume":"136","author":"Moon","year":"1980","journal-title":"J. Comp. Physiol. B"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0405","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.tem.2013.09.002","article-title":"Ketone bodies as signaling metabolites","volume":"25","author":"Newman","year":"2014","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0410","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1074\/jbc.M207880200","article-title":"14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax","volume":"278","author":"Nomura","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0415","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.fsi.2011.05.015","article-title":"Molecular characterization and expression analysis of six peroxiredoxin paralogous genes in gilthead sea bream (Sparus aurata): insights from fish exposed to dietary, pathogen and confinement stressors","volume":"31","author":"P\u00e9rez-S\u00e1nchez","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0420","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1126\/science.1135471","article-title":"Climate change affects marine fishes through the oxygen limitation of thermal tolerance","volume":"315","author":"P\u00f6rtner","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0425","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1086\/499986","article-title":"Trade-offs in thermal adaptation: the need for a molecular to ecological integration","volume":"79","author":"P\u00f6rtner","year":"2006","journal-title":"Physiol. Biochem. Zool."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0430","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1098\/rstb.2006.1947","article-title":"Thermal limits and adaptation in marine Antarctic ectotherms: an integrative view","volume":"362","author":"P\u00f6rtner","year":"2007","journal-title":"Philos. Trans. R. Soc. Lond. B: Biol. Sci."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0435","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.aquatox.2010.09.014","article-title":"Mutagenic impact on fish of runoff events in agricultural areas in south-west France","volume":"101","author":"Polard","year":"2011","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0440","series-title":"Caract\u00e9risation des effets g\u00e9notoxiques sur poissons de produits phytosanitaires en p\u00e9riode de crue. PhD Thesis","author":"Polard","year":"2011"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0445","doi-asserted-by":"crossref","first-page":"6458","DOI":"10.1073\/pnas.93.13.6458","article-title":"Mitochondria are selective targets for the protective effects of heat shock against oxidative injury","volume":"93","author":"Polla","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0450","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.marenvres.2013.07.006","article-title":"Oxidative pathways of chemical toxicity and oxidative stress biomarkers in marine organisms","volume":"93","author":"Regoli","year":"2014","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0455","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.scitotenv.2013.07.110","article-title":"Looking for protein expression signatures in European eel peripheral blood mononuclear cells after in vivo exposure to perfluorooctane sulfonate and a real world field study","volume":"468\u2013469","author":"Roland","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0460","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1046\/j.1461-0248.2003.00528.x","article-title":"The evolutionary and ecological role of heat shock proteins","volume":"6","author":"S\u00f8rensen","year":"2003","journal-title":"Ecol. Lett."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0465","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.aquatox.2009.08.002","article-title":"Liver proteome response of largemouth bass (Micropterus salmoides) exposed to several environmental contaminants: potential insights into biomarker development","volume":"95","author":"Sanchez","year":"2009","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0470","doi-asserted-by":"crossref","first-page":"755","DOI":"10.3945\/an.112.002758","article-title":"Homocysteine imbalance: a pathological metabolic marker","volume":"3","author":"Schalinske","year":"2012","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0475","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.marenvres.2006.03.001","article-title":"Oxidative stress response of European flounder (Platichthys flesus) to cadmium determined by a custom cDNA microarray","volume":"62","author":"Sheader","year":"2006","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0480","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1126\/science.1227166","article-title":"Suppression of oxidative stress by \u03b2-hydroxybutyrate, an endogenous histone deacetylase inhibitor","volume":"339","author":"Shimazu","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0485","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.aquatox.2011.11.002","article-title":"The interactive effects of ammonia exposure, nutritional status and exercise on metabolic and physiological responses in gold fish (Carassius auratus L.)","volume":"109","author":"Sinha","year":"2012","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0490","first-page":"2","article-title":"A review: oxidative stress in fish induced by pesticides","volume":"30","author":"Slaninov\u00e1","year":"2009","journal-title":"Neuroendocrinol. Lett."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0495","doi-asserted-by":"crossref","first-page":"33563","DOI":"10.1074\/jbc.M806578200","article-title":"H2O2-dependent hyperoxidation of peroxiredoxin 6 (Prdx6) plays a role in cellular toxicity via upregulation of iPLA2 activity","volume":"283","author":"So","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0500","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S1096-4959(02)00022-2","article-title":"Energy metabolism of fish brain","volume":"131","author":"Soengas","year":"2002","journal-title":"Comp. Biochem. Physiol. B: Biochem. Mol. Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0505","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3354\/cr00764","article-title":"Interactive effects of metal pollution and temperature on metabolism in aquatic ectotherms: implications of global climate change","volume":"37","author":"Sokolova","year":"2008","journal-title":"Clim. Res."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0510","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.marenvres.2012.04.003","article-title":"Energy homeostasis as an integrative tool for assessing limits of environmental stress tolerance in aquatic invertebrates","volume":"79","author":"Sokolova","year":"2012","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0515","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1093\/icb\/ict028","article-title":"Energy-limited tolerance to stress as a conceptual framework to integrate the effects of multiple stressors","author":"Sokolova","year":"2013","journal-title":"Integr. Comp. Biol"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0520","first-page":"369","article-title":"Effect of herbicides on fish","volume":"vol. 33","author":"Solomon","year":"2013"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0525","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0960-8966(03)00101-9","article-title":"Muscle disease caused by mutations in the skeletal muscle alpha-actin gene (ACTA1)","volume":"13","author":"Sparrow","year":"2003","journal-title":"Neuromuscul. Disord."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0530","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.etap.2011.12.019","article-title":"Effect of chronic exposure to simazine on oxidative stress and antioxidant response in common carp (Cyprinus carpio L.)","volume":"33","author":"Stara","year":"2012","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0535","unstructured":"Statistiques Minist\u00e8re de l\u2019Environnement, France, Pesticides in water, 2015. [Online]. Available: http:\/\/www.statistiques.developpement-durable.gouv.fr\/lessentiel\/ar\/246\/211\/contamination-globale-cours-deaupesticides.html."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0540","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.cbpb.2013.06.006","article-title":"Elevated temperature and pco2 shift metabolic pathways in differentially oxidative tissues of notothenia rossii","volume":"166","author":"Strobel","year":"2013","journal-title":"Comp. Biochem. Physiol.: B Biochem. Mol. Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0545","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.scitotenv.2016.06.014","article-title":"Risk assessment of pesticides used in rice-prawn concurrent systems in Bangladesh","volume":"568","author":"Sumona","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0550","doi-asserted-by":"crossref","first-page":"668","DOI":"10.4161\/cbt.6.5.3955","article-title":"Expression profiling reveals dysregulation of cellular cytoskeletal genes in HBx-induced hepatocarcinogenesis","volume":"6","author":"Sun","year":"2007","journal-title":"Cancer Biol. Ther."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0555","doi-asserted-by":"crossref","first-page":"06","DOI":"10.1051\/kmae\/2011002","article-title":"The role of storm flows in concentration of pesticides associated with particulate and dissolved fractions as a threat to aquatic ecosystems\u2014case study: the agricultural watershed of Save river (Southwest of France)","author":"Taghavi","year":"2011","journal-title":"Knowl. Manag. Aquat. Ecosyst."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0560","doi-asserted-by":"crossref","first-page":"955","DOI":"10.2174\/138161206776055958","article-title":"NAD+-linked 15-hydroxyprostaglandin dehydrogenase: structure and biological functions","volume":"12","author":"Tai","year":"2006","journal-title":"Curr. Pharmacol. Des."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0565","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.gde.2011.01.003","article-title":"Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations","volume":"21","author":"Tischfield","year":"2011","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0570","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1002\/hep.20277","article-title":"Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease","volume":"40","author":"Toivola","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0575","first-page":"128","article-title":"Exposure to tebuconazol in rice field and laboratory conditions induces oxidative stress in carp (Cyprinus carpio)","volume":"153","author":"Toni","year":"2011","journal-title":"Comp. Biochem. Physiol. C: Toxicol. Pharmacol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0580","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.bbalip.2012.07.017","article-title":"Physiological roles of phosphatidylethanolamine N-methyltransferase","volume":"1831","author":"Vance","year":"2013","journal-title":"Biochim. Biophys. Acta: Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0585","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S1096-4959(00)00333-X","article-title":"Cloning of glycerol-3-phosphate dehydrogenase cDNAs from two fish species and effect of temperature on enzyme expression in rainbow smelt (Osmerus mordax)","volume":"128","author":"Vanya Ewart","year":"2001","journal-title":"Comp. Biochem. Physiol. B: Biochem. Mol. Biol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0590","doi-asserted-by":"crossref","first-page":"15074","DOI":"10.3390\/ijms140715074","article-title":"Defective homocysteine metabolism: potential implications for skeletal muscle malfunction","volume":"14","author":"Veeranki","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0595","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1023\/B:FISH.0000035938.92027.81","article-title":"Correlation between heat-shock protein induction and reduced metabolic condition in juvenile steelhead trout (Oncorhynchus mykiss) chronically exposed to elevated temperature","volume":"29","author":"Viant","year":"2003","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0600","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0305-0491(82)90201-2","article-title":"Aspects of intermediary metabolism in salmonid fish","volume":"73","author":"Walton","year":"1982","journal-title":"Comp. Biochem. Physiol. Part B: Comp. Biochem."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0605","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s10646-007-0187-4","article-title":"Proteomic study of the effects of complex environmental stresses in the livers of goldfish (Carassius auratus) that inhabit Gaobeidian Lake in Beijing","volume":"17","author":"Wang","year":"2008","journal-title":"China. Ecotoxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0610","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.aquatox.2013.01.012","article-title":"Quantitative proteomic analysis reveals the mode-of-action for chronic mercury hepatotoxicity to marine medaka (Oryzias melastigma)","volume":"130\u2013131","author":"Wang","year":"2013","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0615","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1093\/toxsci\/kft017","article-title":"Transcriptome alterations following developmental atrazine exposure in zebrafish are associated with disruption of neuroendocrine and reproductive system function, cell cycle, and carcinogenesis","volume":"132","author":"Weber","year":"2013","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0620","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1080\/01926230490518244","article-title":"Toxicoproteomics: proteomics applied to toxicology and pathology","volume":"32","author":"Wetmore","year":"2004","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0625","first-page":"14","article-title":"Destabilisation of dimeric3 proteins as a novel approach to anti-cancer therapeutics","author":"Woodcock","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0630","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.tox.2007.03.021","article-title":"Aberrant DNA methylation and gene expression in livers of newborn mice transplacentally exposed to a hepatocarcinogenic dose of inorganic arsenic","volume":"236","author":"Xie","year":"2007","journal-title":"Toxicology"},{"key":"10.1016\/j.aquatox.2017.01.004_bib0635","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.pestbp.2012.03.007","article-title":"Oxidative stress response and histopathological changes due to atrazine and chlorpyrifos exposure in common carp","volume":"103","author":"Xing","year":"2012","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0640","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.ecoenv.2014.12.040","article-title":"Assessment of pesticide residues and gene expression in common carp exposed to atrazine and chlorpyrifos: health risk assessments","volume":"113","author":"Xing","year":"2015","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0645","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.aquatox.2014.11.020","article-title":"1H NMR based metabolomics approach to study the toxic effects of herbicide butachlor on goldfish (Carassius auratus)","volume":"159","author":"Xu","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0650","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/bbrc.2000.3359","article-title":"The role of regucalcin in nuclear regulation of regenerating liver","volume":"276","author":"Yamaguchi","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0655","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.abb.2004.01.003","article-title":"Hypoxic upregulation of triosephosphate isomerase expression in mouse brain capillary endothelial cells","volume":"423","author":"Yamaji","year":"2004","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0660","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/S0002-9440(10)64997-8","article-title":"Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies","volume":"156","author":"Zatloukal","year":"2000","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0665","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.etap.2013.07.008","article-title":"Comparative antioxidant responses in liver of Carassius auratus exposed to phthalates: an integrated biomarker approach","volume":"36","author":"Zheng","year":"2013","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.aquatox.2017.01.004_bib0670","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0378-4274(01)00365-4","article-title":"Both hypomethylation and hypermethylation of DNA associated with arsenite exposure in cultures of human cells identified by methylation-sensitive arbitrarily-primed PCR","volume":"122","author":"Zhong","year":"2001","journal-title":"Toxicol. Lett."}],"container-title":["Aquatic Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X17300127?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X17300127?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T09:26:29Z","timestamp":1530091589000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166445X17300127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":134,"alternative-id":["S0166445X17300127"],"URL":"https:\/\/doi.org\/10.1016\/j.aquatox.2017.01.004","relation":{},"ISSN":["0166-445X"],"issn-type":[{"value":"0166-445X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Proteome response of fish under multiple stress exposure: Effects of pesticide mixtures and temperature increase","name":"articletitle","label":"Article Title"},{"value":"Aquatic Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aquatox.2017.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}