{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:39:24Z","timestamp":1786984764479,"version":"build-2736575974"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001824","name":"Czech Science Foundation","doi-asserted-by":"crossref","award":["16-06498S"],"award-info":[{"award-number":["16-06498S"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Ministry of Education, Youth and Sports of the Czech Republic","award":["LM2018099"],"award-info":[{"award-number":["LM2018099"]}]},{"name":"CENAKVA Center Development","award":["CZ.1.05\/2.1.00\/19.0380"],"award-info":[{"award-number":["CZ.1.05\/2.1.00\/19.0380"]}]},{"name":"Grant Agency of University of South Bohemia","award":["061\/2019\/Z"],"award-info":[{"award-number":["061\/2019\/Z"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Aquatic Toxicology"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.aquatox.2019.05.019","type":"journal-article","created":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T11:10:36Z","timestamp":1559301036000},"page":"105217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Behaviour and cardiac response to stress in signal crayfish exposed to environmental concentrations of tramadol"],"prefix":"10.1016","volume":"213","author":[{"given":"F.","family":"Lo\u017eek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Kuklina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Grabicov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Kubec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bu\u0159i\u010d","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Grabic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Rand\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"C\u00edsa\u0159","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Koz\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aquatox.2019.05.019_bib0005","doi-asserted-by":"crossref","first-page":"19021","DOI":"10.1007\/s11356-017-9525-0","article-title":"Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river","volume":"24","author":"Azuma","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0010","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1080\/02772248.2014.966713","article-title":"Fluoxetine inhibits predator avoidance behavior in tadpoles","volume":"96","author":"Barry","year":"2014","journal-title":"Toxicol. Environ. Chem."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0015","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1289\/ehp.1104477","article-title":"Pharmaceuticals and personal care products in the environment: what are the big questions?","volume":"120","author":"Boxall","year":"2012","journal-title":"Environ. Health Perspect."},{"issue":"80","key":"10.1016\/j.aquatox.2019.05.019_bib0020","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1126\/science.1226850","article-title":"Dilute concentrations of a psychiatric drug alter behavior of fish from natural populations","volume":"339","author":"Brodin","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0025","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2013.0580","article-title":"Ecological effects of pharmaceuticals in aquatic systems\u2014impacts through behavioural alterations","volume":"369","author":"Brodin","year":"2014","journal-title":"Philos. Trans. R. Soc. B Biol. Sci."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0030","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.scitotenv.2018.07.109","article-title":"Modulation of mitochondrial functions by xenobiotic-induced microRNA: from environmental sentinel organisms to mammals","volume":"645","author":"Burgos-Aceves","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0035","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.ecoenv.2017.12.001","article-title":"MicroRNAs and their role on fish oxidative stress during xenobiotic environmental exposures","volume":"148","author":"Burgos-Aceves","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0040","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.aquatox.2018.05.008","article-title":"Environmentally relevant concentrations of tramadol and citalopram alter behaviour of an aquatic invertebrate","volume":"200","author":"Bu\u0159i\u010d","year":"2018","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0045","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.fsi.2005.03.002","article-title":"Effects of dopamine on the immunity of white shrimp Litopenaeus vannamei","volume":"19","author":"Cheng","year":"2005","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0050","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1899\/0887-3593(2004)023<0224:EEBCIA>2.0.CO;2","article-title":"Ecosystem engineering by crayfish in a headwater stream community","volume":"23","author":"Creed","year":"2004","journal-title":"J. North Am. Benthol. Soc."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0055","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.aquatox.2006.03.002","article-title":"Behavioural responses of Gammarus pulex (Crustacea, Amphipoda) to low concentrations of pharmaceuticals","volume":"78","author":"De Lange","year":"2006","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0060","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/10807030802615584","article-title":"Changes in ventilation and locomotion of Gammarus pulex (Crustacea, Amphipoda) in response to low concentrations of pharmaceuticals","volume":"15","author":"De Lange","year":"2009","journal-title":"Hum. Ecol. Risk Assess."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0065","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S0165-9936(03)00603-4","article-title":"Environmental behavior and analysis of veterinary and human drugs in soils, sediments and sludge","volume":"22","author":"D\u00edaz-Cruz","year":"2003","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0070","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/s00442-004-1548-9","article-title":"The role of omnivorous crayfish in littoral communities","volume":"140","author":"Dorn","year":"2004","journal-title":"Oecologia"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0075","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.chroma.2012.07.026","article-title":"Evaluation of an isotope dilution liquid chromatography tandem mass spectrometry method for pharmaceuticals in fish","volume":"1253","author":"Du","year":"2012","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0080","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.scitotenv.2013.12.091","article-title":"A passive sampling method for detecting analgesics, psycholeptics, antidepressants and illicit drugs in aquatic environments in the Czech Republic","volume":"487","author":"Fedorova","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0085","first-page":"151","article-title":"The biological effects of antidepressants on the molluscs and crustaceans: a review","author":"Fong","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0090","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1080\/10236244.2012.690579","article-title":"Antidepressants (venlafaxine and citalopram) cause foot detachment from the substrate in freshwater snails at environmentally relevant concentrations","volume":"45","author":"Fong","year":"2012","journal-title":"Mar. Freshw. Behav. Physiol."},{"issue":"80","key":"10.1016\/j.aquatox.2019.05.019_bib0095","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1126\/science.1248811","article-title":"Anxiety-like behavior in crayfish is controlled by serotonin","volume":"344","author":"Fossat","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0100","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.scitotenv.2013.03.078","article-title":"Uptake of human pharmaceuticals in bull sharks (Carcharhinus leucas) inhabiting a wastewater-impacted river","volume":"456","author":"Gelsleichter","year":"2013","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0105","first-page":"269","article-title":"Infraorder Astacidea Latreille, 1802 P.P.: the freshwater crayfish","author":"Gherardi","year":"2010","journal-title":"Crustacea"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0110","doi-asserted-by":"crossref","first-page":"7578","DOI":"10.1007\/s11356-014-2654-9","article-title":"Removal and seasonal variability of selected analgesics\/anti-inflammatory, anti-hypertensive\/cardiovascular pharmaceuticals and UV filters in wastewater treatment plant","volume":"21","author":"Golovko","year":"2014","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0115","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.talanta.2012.08.032","article-title":"Multi-residue method for trace level determination of pharmaceuticals in environmental samples using liquid chromatography coupled to triple quadrupole mass spectrometry","volume":"100","author":"Grabic","year":"2012","journal-title":"Talanta"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0120","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.watres.2014.09.018","article-title":"Presence of pharmaceuticals in benthic fauna living in a small stream affected by effluent from a municipal sewage treatment plant","volume":"72","author":"Grabicova","year":"2015","journal-title":"Water Res."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0125","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.watres.2017.08.018","article-title":"Bioaccumulation of psychoactive pharmaceuticals in fish in an effluent dominated stream","volume":"124","author":"Grabicova","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0130","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0378-4274(02)00041-3","article-title":"Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data","volume":"131","author":"Heberer","year":"2002","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0135","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/s10646-017-1880-6","article-title":"Behaviour of freshwater snails (Radix balthica) exposed to the pharmaceutical sertraline under simulated predation risk","volume":"27","author":"Hedgespeth","year":"2018","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0140","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s003590050204","article-title":"Serotonin alters decisions to withdraw in fighting crayfish, Astacus astacus: the motivational concept revisited","volume":"182","author":"Huber","year":"1998","journal-title":"J. Comp. Physiol. A"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0145","doi-asserted-by":"crossref","first-page":"5939","DOI":"10.1073\/pnas.94.11.5939","article-title":"Serotonin and aggressive motivation in crustaceans: altering the decision to retreat","volume":"94","author":"Huber","year":"1997","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0150","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3390\/w11020196","article-title":"Oxazepam alters the behavior of crayfish at diluted concentrations, venlafaxine does not","volume":"11","author":"Kubec","year":"2019","journal-title":"Water"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0155","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jcz.2018.10.009","article-title":"Communication, behavior and decision making in crayfish: a review","volume":"278","author":"Kubec","year":"2019","journal-title":"Zool. Anz."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0160","doi-asserted-by":"crossref","first-page":"5043","DOI":"10.1007\/s10661-012-2924-2","article-title":"Real-time monitoring of water quality using fish and crayfish as bio-indicators: a review","volume":"185","author":"Kuklina","year":"2013","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0165","doi-asserted-by":"crossref","first-page":"8396","DOI":"10.1007\/s11356-017-1183-8","article-title":"Crayfish can distinguish between natural and chemical stimuli as assessed by cardiac and locomotor reactions","volume":"25","author":"Kuklina","year":"2018","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0170","first-page":"e58555","article-title":"Continuous noninvasive measuring of crayfish cardiac and behavioral activities","volume":"144","author":"Kuklina","year":"2019","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0175","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/07924259.1992.9672242","article-title":"In vivo stimulation of ovarian development in the red swamp crayfish, procambarus clarkii (Girard), by 5-hydroxytryptamine","volume":"21","author":"Kulkarni","year":"1992","journal-title":"Invertebr. Reprod. Dev."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0180","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1185\/03007990903426787","article-title":"Adverse event profile of tramadol in recent clinical studies of chronic osteoarthritis pain","volume":"26","author":"Langley","year":"2010","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0185","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/j.watres.2010.10.032","article-title":"Evaluating environmental impact of STPs situated on streams in the Czech Republic: an integrated approach to biomonitoring the aquatic environment","volume":"45","author":"Li","year":"2011","journal-title":"Water Res."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0190","doi-asserted-by":"crossref","first-page":"670","DOI":"10.4319\/lom.2014.12.670","article-title":"Noninvasive crayfish cardiac activity monitoring system","volume":"12","author":"Pautsina","year":"2014","journal-title":"Limnol. Oceanogr. Methods"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0195","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.chemosphere.2008.06.029","article-title":"Fluoxetine effects assessment on the life cycle of aquatic invertebrates","volume":"73","author":"P\u00e9ry","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0200","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0165-9936(03)01105-1","article-title":"Analysis and removal of emerging contaminants in wastewater and drinking water","volume":"22","author":"Petrovi\u0107","year":"2003","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0205","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1039\/c2em10950f","article-title":"Impact of wastewater treatment plant discharge of lidocaine, tramadol, venlafaxine and their metabolites on the quality of surface waters and groundwater","volume":"14","author":"R\u00faa-G\u00f3mez","year":"2012","journal-title":"J. Environ. Monit."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0210","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.chemosphere.2017.08.151","article-title":"Toxicity of naproxen sodium and its mixture with tramadol hydrochloride on fish early life stages","volume":"188","author":"Sehonova","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0215","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.scitotenv.2018.03.076","article-title":"Effects of waterborne antidepressants on non-target animals living in the aquatic environment: a review","volume":"631\u2013632","author":"Sehonova","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0220","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.scitotenv.2019.02.202","article-title":"Acute exposure of common yabby (Cherax destructor) to the neonicotinoid pesticide","volume":"665","author":"Stara","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0225","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.chemosphere.2019.02.187","article-title":"Effects of S-metolachlor and its degradation product metolachlor OA on marbled crayfish (Procambarus virginalis)","volume":"224","author":"Stara","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0230","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1517\/14740338.7.5.587","article-title":"Drug-induced serotonin syndrome: a review","volume":"7","author":"Sun-Edelstein","year":"2008","journal-title":"Expert Opin. Drug Saf."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0235","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/jawr.12164","article-title":"Screening for selected human pharmaceuticals and cocaine in the urban streams of Manaus, Amazonas","volume":"50","author":"Thomas","year":"2014","journal-title":"Brazil. JAWRA J. Am. Water Resour. Assoc."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0240","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1080\/10236244.2015.1119974","article-title":"Effects of fluoxetine on growth and behavior in the crayfish Orconectes rusticus","volume":"49","author":"Tierney","year":"2016","journal-title":"Mar. Freshw. Behav. Physiol."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0245","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0044-8486(99)00267-7","article-title":"Ovarian maturation and spawning in the white shrimp, Penaeus vannamei, by serotonin injection","volume":"182","author":"Vaca","year":"2000","journal-title":"Aquaculture"},{"key":"10.1016\/j.aquatox.2019.05.019_bib0250","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1021\/es204164b","article-title":"Human therapeutic plasma levels of the selective serotonin reuptake inhibitor (SSRI) sertraline decrease serotonin reuptake transporter binding and shelter-seeking behavior in adult male fathead minnows","volume":"46","author":"Valenti","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0255","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s00427-005-0055-2","article-title":"Early embryonic development of the central nervous system in the Australian crayfish and the Marbled crayfish (Marmorkrebs)","volume":"216","author":"Vilpoux","year":"2006","journal-title":"Dev. Genes Evol."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0260","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.aquatox.2013.10.012","article-title":"Environmental concentrations of the selective serotonin reuptake inhibitor fluoxetine impact specific behaviors involved in reproduction, feeding and predator avoidance in the fish Pimephales promelas (fathead minnow)","volume":"151","author":"Weinberger","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2019.05.019_bib0265","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/j.aquaculture.2006.08.044","article-title":"Serotonin stimulates ovarian maturation and spawning in the black tiger shrimp Penaeus monodon","volume":"261","author":"Wongprasert","year":"2006","journal-title":"Aquaculture"}],"container-title":["Aquatic Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X19302024?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X19302024?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T13:50:32Z","timestamp":1759067432000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166445X19302024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":53,"alternative-id":["S0166445X19302024"],"URL":"https:\/\/doi.org\/10.1016\/j.aquatox.2019.05.019","relation":{},"ISSN":["0166-445X"],"issn-type":[{"value":"0166-445X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Behaviour and cardiac response to stress in signal crayfish exposed to environmental concentrations of tramadol","name":"articletitle","label":"Article Title"},{"value":"Aquatic Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aquatox.2019.05.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105217"}}