{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T23:18:39Z","timestamp":1794093519415,"version":"4.8.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100011002","name":"National Natural Science Foundation of China-Yunnan Joint Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Aquatic Toxicology"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.aquatox.2019.105295","type":"journal-article","created":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T11:20:07Z","timestamp":1567768807000},"page":"105295","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"special_numbering":"C","title":["The toxicological effects of oxybenzone, an active ingredient in suncream personal care products, on prokaryotic alga Arthrospira sp. and eukaryotic alga Chlorella sp."],"prefix":"10.1016","volume":"216","author":[{"given":"Xin","family":"Zhong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig A.","family":"Downs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingkai","family":"Che","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zishan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiman","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binbin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiyuan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.aquatox.2019.105295_bib0005","doi-asserted-by":"crossref","first-page":"3496","DOI":"10.1007\/s11356-013-1586-0","article-title":"New trends in the analytical determination of emerging contaminants and their transformation products in environmental waters","volume":"20","author":"Ag\u00fcera","year":"2013","journal-title":"Environ. Sci. Pollut. Res. - Int."},{"issue":"4","key":"10.1016\/j.aquatox.2019.105295_bib0010","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/j.1600-0536.1992.tb03268.x","article-title":"Allergic contact cheilitis from a lipstick containing oxybenzone","volume":"27","author":"Aguirre","year":"1992","journal-title":"Contact Derm."},{"key":"10.1016\/j.aquatox.2019.105295_bib0015","doi-asserted-by":"crossref","first-page":"9080","DOI":"10.1021\/es3014453","article-title":"The xenometabolome and novel contaminant markers in fish exposed to a wastewater treatment works effluent","volume":"46","author":"Alsalhi","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.aquatox.2019.105295_bib0020","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/oxfordjournals.pcp.a078983","article-title":"Chlorophyll amount as an indicator of matter productivity in bio-communities","volume":"4","author":"Aruga","year":"1963","journal-title":"Plant Cell Physiol."},{"issue":"4","key":"10.1016\/j.aquatox.2019.105295_bib0025","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1021\/es040055r","article-title":"Occurrence of some organic UV filters in wastewater, in surface waters, and in fish from Swiss lakes","volume":"39","author":"Balmer","year":"2005","journal-title":"Environ. Sci. Technol."},{"issue":"5","key":"10.1016\/j.aquatox.2019.105295_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaad.2008.06.013","article-title":"Possible environmental effects of sunscreen run-off","volume":"59","author":"Blitz","year":"2008","journal-title":"J. Am. Acad. Dermatol."},{"issue":"2","key":"10.1016\/j.aquatox.2019.105295_bib0035","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1093\/aob\/mcf118","article-title":"Antioxidants, oxidative damage and oxygen deprivation stress: a review","volume":"91","author":"Blokhina","year":"2003","journal-title":"Ann. Bot."},{"key":"10.1016\/j.aquatox.2019.105295_bib0040","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.taap.2012.06.008","article-title":"Effects of the UV filter benzophenone-3 (oxybenzone) at low concentrations in zebrafish (Danio rerio)","volume":"263","author":"Bl\u00fcthgen","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.aquatox.2019.105295_bib0045","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/nature09268","article-title":"Global phytoplankton decline over the past century","volume":"466","author":"Boyce","year":"2010","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.aquatox.2019.105295_bib0050","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1104\/pp.60.1.165","article-title":"Net photosynthesis, electron transport capacity, and ultrastructure of Pisum sativum L. exposed to ultraviolet-B radiation","volume":"60","author":"Brandle","year":"1977","journal-title":"Plant Physiol."},{"key":"10.1016\/j.aquatox.2019.105295_bib0055","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.chemosphere.2017.05.072","article-title":"Fate of the sunscreen compound oxybenzone in Cyperus alternifolius based hydroponic culture: uptake, biotransformation and phytotoxicity","volume":"182","author":"Chen","year":"2017","journal-title":"Chemosphere"},{"issue":"3","key":"10.1016\/j.aquatox.2019.105295_bib0060","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.aquatox.2008.08.018","article-title":"Estrogenic activity and reproductive effects of the UV-filter oxybenzone (2-hydroxy-4-methoxyphenyl-methanone) in fish","volume":"90","author":"Coronado","year":"2008","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.aquatox.2019.105295_bib0065","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1055\/s-2004-817845","article-title":"Changes in activity of energy dissipating mechanisms in wheat flag leaves during senescence","volume":"6","author":"Dai","year":"2010","journal-title":"Plant Biol."},{"key":"10.1016\/j.aquatox.2019.105295_bib0070","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1289\/ehp.10966","article-title":"Sunscreens cause coral bleaching by promoting viral infections","volume":"116","author":"Danovaro","year":"2008","journal-title":"Environ. Health Perspect."},{"issue":"2","key":"10.1016\/j.aquatox.2019.105295_bib0075","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00244-015-0227-7","article-title":"Toxicopathological effects of the sunscreen UV filter, oxybenzone (benzophenone-3), on coral planulae and cultured primary cells and its environmental contamination in Hawaii and the U.S. Virgin Islands","volume":"70","author":"Downs","year":"2016","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.aquatox.2019.105295_bib0080","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1067\/mai.2001.112430","article-title":"Anaphylaxis to oxybenzone, a frequent constituent of sunscreens","volume":"107","author":"Emonet","year":"2001","journal-title":"J. Allergy Clin. Immunol."},{"issue":"1","key":"10.1016\/j.aquatox.2019.105295_bib0085","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1104\/pp.71.1.182","article-title":"Inhibition by calcium of senescence of detached cucumber cotyledons","volume":"71","author":"Freguson","year":"1983","journal-title":"Plant Physiol."},{"issue":"1","key":"10.1016\/j.aquatox.2019.105295_bib0090","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0304-4165(89)80016-9","article-title":"The relationship between the quantum yield of photosynthetic electron transport and quenching of chlorophyll fluorescence","volume":"990","author":"Genty","year":"1989","journal-title":"BBA-Gen. Subj."},{"issue":"15","key":"10.1016\/j.aquatox.2019.105295_bib0095","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1029\/2002GL014689","article-title":"Decadal changes in global ocean chlorophyll","volume":"29","author":"Gregg","year":"2002","journal-title":"Geophys. Res. Lett."},{"issue":"1","key":"10.1016\/j.aquatox.2019.105295_bib0100","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0003-9861(68)90654-1","article-title":"Photoperoxidation in isolated chloroplasts: I. Kinetics and stoichiometry of fatty acid peroxidation","volume":"125","author":"Heath","year":"1968","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.aquatox.2019.105295_bib0105","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.0303-6979.2004.00453.x","article-title":"Effect of oxybenzone on PGE2-production in vitro and on plaque and gingivitis in vivo","volume":"31","author":"Jannesson","year":"2010","journal-title":"J. Clin. Periodontol."},{"issue":"5414","key":"10.1016\/j.aquatox.2019.105295_bib0110","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1126\/science.284.5414.654","article-title":"Systemic signaling and acclimation in response to excess excitation energy in Arabidopsis","volume":"284","author":"Karpinski","year":"1999","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.aquatox.2019.105295_bib0115","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.taap.2007.05.016","article-title":"Percutaneous characterization of the insect repellent DEET and the sunscreen oxybenzone from topical skin application","volume":"223","author":"Kasichayanula","year":"2007","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.aquatox.2019.105295_bib0120","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1210\/js.2018-00024","article-title":"Oxybenzone alters mammary gland morphology in mice exposed during pregnancy and lactation","volume":"2","author":"Laplante","year":"2018","journal-title":"J. Endocr. Soc."},{"issue":"15","key":"10.1016\/j.aquatox.2019.105295_bib0125","doi-asserted-by":"crossref","first-page":"3506","DOI":"10.1016\/j.watres.2007.05.039","article-title":"Occurrence and behavior of four of the most used sunscreen UV filters in a wastewater reclamation plant","volume":"41","author":"Li","year":"2007","journal-title":"Water Res."},{"key":"10.1016\/j.aquatox.2019.105295_bib0130","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1007\/s10529-009-9975-7","article-title":"Biomass and lipid productivities of Chlorella vulgaris under autotrophic, heterotrophic and mixotrophic growth conditions","volume":"31","author":"Liang","year":"2009","journal-title":"Biotechnol. Lett."},{"issue":"1\u20132","key":"10.1016\/j.aquatox.2019.105295_bib0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2004.04.041","article-title":"Increased ATP content\/production in the hypothalamus may be a signal for energy-sensing of satiety: studies of the anorectic mechanism of a plant steroidal glycoside","volume":"1020","author":"Maclean","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.aquatox.2019.105295_bib0140","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.scitotenv.2017.02.185","article-title":"Contamination sources and distribution patterns of pharmaceuticals and personal care products in Alpine rivers strongly affected by tourism","volume":"590\u2013591","author":"Mandaric","year":"2017","journal-title":"Sci. Total Environ."},{"issue":"8","key":"10.1016\/j.aquatox.2019.105295_bib0145","first-page":"1","article-title":"Evaluating the joint toxicity of two benzophenone-type UV filters on the green alga Chlamydomonas reinhardtii with response surface methodology","volume":"6","author":"Mao","year":"2018","journal-title":"Toxics"},{"key":"10.1016\/j.aquatox.2019.105295_bib0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aquatox.2017.09.029","article-title":"Effects of benzophenone-3 on the green alga Chlamydomonas reinhardtii and the cyanobacterium Microcystis aeruginosa","volume":"193","author":"Mao","year":"2017","journal-title":"Aquat. Toxicol."},{"issue":"345","key":"10.1016\/j.aquatox.2019.105295_bib0155","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1093\/jexbot\/51.345.659","article-title":"Chlorophyll fuorescence\u2014a practical guide","volume":"51","author":"Maxwell","year":"2000","journal-title":"J. Exp. Bot."},{"issue":"1\u20132","key":"10.1016\/j.aquatox.2019.105295_bib0160","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0014-5793(86)80149-1","article-title":"Respiratory electron transport in plasma and thylakoid membrane preparations from the cyanobacterium Anacystis nidulans","volume":"195","author":"Molitor","year":"1986","journal-title":"FEBS Lett."},{"key":"10.1016\/j.aquatox.2019.105295_bib0165","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1146\/annurev.arplant.52.1.561","article-title":"Plant mitochondria and oxidative stress: electron transport, NADPH turnover, and metabolism of reactive oxygen species","volume":"52","author":"Moller","year":"2001","journal-title":"Annu. Rev. Plant Physiol. Plant Mol. Biol."},{"issue":"1\u20133","key":"10.1016\/j.aquatox.2019.105295_bib0170","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1023\/A:1020470224740","article-title":"The chequered history of the development and use of simultaneous equations for the accurate determination of chlorophylls a and b","volume":"73","author":"Porra","year":"2002","journal-title":"Photosynth. Res."},{"issue":"7","key":"10.1016\/j.aquatox.2019.105295_bib0175","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1093\/jxb\/erm240","article-title":"Regulation of Rubisco activase and its interaction with Rubisco","volume":"59","author":"Portis","year":"2008","journal-title":"J. Exp. Bot."},{"issue":"10","key":"10.1016\/j.aquatox.2019.105295_bib0180","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1093\/jxb\/erv099","article-title":"ROS and RNS in plant physiology: an overview","volume":"66","author":"R\u00edo","year":"2015","journal-title":"J. Exp. Bot."},{"issue":"1","key":"10.1016\/j.aquatox.2019.105295_bib0185","first-page":"1","article-title":"Generic assignments, strain histories and properties of pure cultures of cyanobacteria","volume":"111","author":"Rippka","year":"1979","journal-title":"J. Gen. Microbiol."},{"issue":"10","key":"10.1016\/j.aquatox.2019.105295_bib0190","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.chemosphere.2011.11.053","article-title":"Emerging pollutants in sewage, surface and drinking water in Galicia (NW Spain)","volume":"86","author":"Rodil","year":"2012","journal-title":"Chemosphere"},{"issue":"1","key":"10.1016\/j.aquatox.2019.105295_bib0195","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1042\/bj1930099","article-title":"Production of superoxide radicals by soluble hydrogenase from Alcaligenes eutrophus H16","volume":"193","author":"Schneider","year":"1981","journal-title":"Biochem. J."},{"key":"10.1016\/j.aquatox.2019.105295_bib0200","first-page":"1311","article-title":"Acute and chronic toxicity of four frequently used UV filter substances for Desmodesmus subspicatus and Daphnia magna","volume":"46","author":"Sieratowicz","year":"2011","journal-title":"J. Environ. Sci. Health A. Tox. Subst. Environ. Eng."},{"key":"10.1016\/j.aquatox.2019.105295_bib0205","series-title":"Probing Photosynthesis","first-page":"445","article-title":"The fluorescence transient as a tool to characterize and screen photosynthetic samples","author":"Strasser","year":"2000"},{"issue":"8","key":"10.1016\/j.aquatox.2019.105295_bib0210","doi-asserted-by":"crossref","first-page":"4182","DOI":"10.1021\/acs.est.6b05211","article-title":"Occurrence, distribution, and fate of organic UV filters in coral communities","volume":"51","author":"Tsui","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.aquatox.2019.105295_bib0215","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.scitotenv.2013.05.090","article-title":"Phototransformation of the sunlight filter benzophenone-3 (2-hydroxy-4-methoxybenzophenone) under conditions relevant to surface waters","volume":"463\u2013464","author":"Vione","year":"2013","journal-title":"Sci. Total Environ."},{"issue":"3","key":"10.1016\/j.aquatox.2019.105295_bib0220","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0144-4565(82)90028-2","article-title":"Production of spirulina biomass: effects of environmental factors and population density","volume":"2","author":"Vonshak","year":"1982","journal-title":"Biomass"},{"key":"10.1016\/j.aquatox.2019.105295_bib0225","series-title":"Report by the International Coral Reef Initiative (ICRI)","article-title":"Impacts of sunscreens on coral reefs","author":"Wood","year":"2018"},{"key":"10.1016\/j.aquatox.2019.105295_bib0230","series-title":"Contribution \u00e0 l\u2019\u00e9tude d\u2019une cyanobact\u00e9rie: Influence de divers facteurs physiques et chimiques sur la croissance et la Photosynth \u00c0se de Spirulina maxima (Setchell et Gardner) Geitler","author":"Zarrouk","year":"1966"},{"key":"10.1016\/j.aquatox.2019.105295_bib0235","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s00425-011-1447-3","article-title":"Characterization of PSI recovery after chilling-induced photoinhibition in cucumber (Cucumis sativus L.) leaves","volume":"234","author":"Zhang","year":"2011","journal-title":"Planta"},{"key":"10.1016\/j.aquatox.2019.105295_bib0240","doi-asserted-by":"crossref","first-page":"4169","DOI":"10.1016\/j.watres.2012.11.058","article-title":"Mitigation of CuO nanoparticleinduced bacterial membrane damage by dissolved organic matter","volume":"47","author":"Zhao","year":"2013","journal-title":"Water Res."},{"key":"10.1016\/j.aquatox.2019.105295_bib0245","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.chemosphere.2018.12.019","article-title":"Significant inhibition of photosynthesis and respiration in leaves of Cucumis sativus L. by oxybenzone, an active ingredient in sunscreen","volume":"219","author":"Zhong","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.aquatox.2019.105295_bib0250","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1104\/pp.90.2.516","article-title":"Coordinate expression of Rubisco activase and Rubisco during barley leaf cell development","volume":"90","author":"Zielinski","year":"1989","journal-title":"Plant Physiol."},{"issue":"2","key":"10.1016\/j.aquatox.2019.105295_bib0255","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1021\/es062367v","article-title":"Drowning in disinfection byproducts? Assessing swimming pool water","volume":"41","author":"Zwiener","year":"2007","journal-title":"Environ. Sci. Technol."}],"container-title":["Aquatic Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X19305934?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166445X19305934?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T13:53:27Z","timestamp":1759067607000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166445X19305934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":51,"alternative-id":["S0166445X19305934"],"URL":"https:\/\/doi.org\/10.1016\/j.aquatox.2019.105295","relation":{},"ISSN":["0166-445X"],"issn-type":[{"value":"0166-445X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The toxicological effects of oxybenzone, an active ingredient in suncream personal care products, on prokaryotic alga Arthrospira sp. and eukaryotic alga Chlorella sp.","name":"articletitle","label":"Article Title"},{"value":"Aquatic Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aquatox.2019.105295","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105295"}}