{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:47:05Z","timestamp":1761896825419,"version":"build-2065373602"},"reference-count":68,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archivos de Bronconeumolog\u00eda"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.arbres.2018.03.006","type":"journal-article","created":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T19:49:47Z","timestamp":1527536987000},"page":"31-37","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Airway Pathological Alterations Selectively Associated With Acute Respiratory Distress Syndrome and Diffuse Alveolar Damage \u2013 Narrative Review"],"prefix":"10.1016","volume":"55","author":[{"given":"Guillermo","family":"Ortiz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Garay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"Capelozzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Cardinal-Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arbres.2018.03.006_bib0345","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1001\/jama.2016.0291","article-title":"Epidemiology patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries","volume":"315","author":"Bellani","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.arbres.2018.03.006_bib0350","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1513\/AnnalsATS.201609-728PS","article-title":"Acute respiratory distress syndrome and diffuse alveolar damage new insights on a complex relationship","volume":"14","author":"Cardinal-Fernandez","year":"2017","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.arbres.2018.03.006_bib0355","first-page":"2526","article-title":"Acute respiratory distress syndrome: the Berlin definition","volume":"307","author":"Ranieri","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.arbres.2018.03.006_bib0360","doi-asserted-by":"crossref","first-page":"e0180018","DOI":"10.1371\/journal.pone.0180018","article-title":"Survival predictor in patients with acute respiratory distress syndrome and diffuse alveolar damage undergoing open lung biopsy","volume":"12","author":"Kao","year":"2017","journal-title":"PLOS ONE"},{"key":"10.1016\/j.arbres.2018.03.006_bib0365","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/s13054-015-0949-y","article-title":"Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy","volume":"19","author":"Kao","year":"2015","journal-title":"Crit Care"},{"key":"10.1016\/j.arbres.2018.03.006_bib0370","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/s00134-014-3583-2","article-title":"Open lung biopsy in nonresolving ARDS frequently identifies diffuse alveolar damage regardless of the severity stage and may have implications for patient management","volume":"41","author":"Guerin","year":"2015","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0375","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.chest.2016.02.635","article-title":"The presence of diffuse alveolar damage on open lung biopsy is associated with mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis","volume":"149","author":"Cardinal-Fernandez","year":"2016","journal-title":"Chest"},{"key":"10.1016\/j.arbres.2018.03.006_bib0380","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1378\/chest.14-0874","article-title":"ARDS: lessons learned from the heart","volume":"147","author":"Cardinal-Fernandez","year":"2015","journal-title":"Chest"},{"key":"10.1016\/j.arbres.2018.03.006_bib0385","first-page":"169","article-title":"Acute respiratory distress: from syndrome to disease","volume":"40","author":"Cardinal-Fernandez","year":"2016","journal-title":"Med Intensiva"},{"key":"10.1016\/j.arbres.2018.03.006_bib0390","doi-asserted-by":"crossref","first-page":"354","DOI":"10.5935\/0103-507X.20170044","article-title":"What every intensivist should know about acute respiratory distress syndrome and diffuse alveolar damage","volume":"29","author":"Rios","year":"2017","journal-title":"Revista Brasileira de Terapia Intensiva"},{"key":"10.1016\/j.arbres.2018.03.006_bib0395","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s00134-014-3272-1","article-title":"Effects of interventions on survival in acute respiratory distress syndrome: an umbrella review of 159 published randomized trials and 29 meta-analyses","volume":"40","author":"Tonelli","year":"2014","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0400","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1513\/AnnalsATS.201601-072OC","article-title":"Acute respiratory distress syndrome measurement error potential effect on clinical study results","volume":"13","author":"Sjoding","year":"2016","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.arbres.2018.03.006_bib0405","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.arbr.2014.09.001","article-title":"Systems medicine: a new approach to clinical practice","volume":"50","author":"Cardinal-Fernandez","year":"2014","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.arbres.2018.03.006_bib0410","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1007\/s00134-015-4046-0","article-title":"Acute respiratory distress syndrome in patients with and without diffuse alveolar damage: an autopsy study","volume":"41","author":"Lorente","year":"2015","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0415","doi-asserted-by":"crossref","first-page":"440","DOI":"10.7326\/0003-4819-141-6-200409210-00009","article-title":"Comparison of clinical criteria for the acute respiratory distress syndrome with autopsy findings","volume":"141","author":"Esteban","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0420","first-page":"209","article-title":"Diffuse alveolar damage \u2013 the role of oxygen, shock, and related factors. A review","volume":"85","author":"Katzenstein","year":"1976","journal-title":"Am J Pathol"},{"key":"10.1016\/j.arbres.2018.03.006_bib0425","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1590\/S1806-37132007000400011","article-title":"Accuracy of clinical diagnosis of acute respiratory distress syndrome in comparison with autopsy findings","volume":"33","author":"Pinheiro","year":"2007","journal-title":"Jornal brasileiro de pneumologia: publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia"},{"key":"10.1016\/j.arbres.2018.03.006_bib0430","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S2213-2600(13)70053-5","article-title":"Chronology of histological lesions in acute respiratory distress syndrome with diffuse alveolar damage: a prospective cohort study of clinical autopsies","volume":"1","author":"Thille","year":"2013","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0435","doi-asserted-by":"crossref","first-page":"165","DOI":"10.5847\/wjem.j.1920-8642.2015.03.001","article-title":"Albuterol in the treatment of acute respiratory distress syndrome: a meta-analysis of randomized controlled trials","volume":"6","author":"Wu","year":"2015","journal-title":"World J Emerg Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0440","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1097\/00003246-200209000-00001","article-title":"Effects of positive end-expiratory pressure on gas exchange and expiratory flow limitation in adult respiratory distress syndrome","volume":"30","author":"Koutsoukou","year":"2002","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0445","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1164\/ajrccm\/139.5.1169","article-title":"The role of airflow resistance in patients with the adult respiratory distress syndrome","volume":"139","author":"Wright","year":"1989","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.arbres.2018.03.006_bib0450","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jcrc.2016.03.015","article-title":"ARDS: time to \u201cseparate the wheat from the chaff\u201d","volume":"34","author":"Cardinal-Fernandez","year":"2016","journal-title":"J Crit Care"},{"key":"10.1016\/j.arbres.2018.03.006_bib0455","doi-asserted-by":"crossref","first-page":"375","DOI":"10.4414\/smw.2009.12270","article-title":"What makes a good lung?","volume":"139","author":"Weibel","year":"2009","journal-title":"Swiss Med Wkly"},{"key":"10.1016\/j.arbres.2018.03.006_bib0460","doi-asserted-by":"crossref","first-page":"S72","DOI":"10.1016\/j.jaci.2009.08.048","article-title":"Anatomy, pathology, and physiology of the tracheobronchial tree: emphasis on the distal airways","volume":"124","author":"Hyde","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.arbres.2018.03.006_bib0465","first-page":"L361","article-title":"Fractal geometry: a design principle for living organisms","volume":"261","author":"Weibel","year":"1991","journal-title":"Am J Physiol"},{"key":"10.1016\/j.arbres.2018.03.006_bib0470","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1126\/science.137.3530.577","article-title":"Architecture of the human lung use of quantitative methods establishes fundamental relations between size and number of lung structures","volume":"137","author":"Weibel","year":"1962","journal-title":"Science"},{"key":"10.1016\/j.arbres.2018.03.006_bib0475","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/nature02287","article-title":"An optimal bronchial tree may be dangerous","volume":"427","author":"Mauroy","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.arbres.2018.03.006_bib0480","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1186\/cc5159","article-title":"Bench-to-bedside review: distal airways in acute respiratory distress syndrome","volume":"11","author":"Jain","year":"2007","journal-title":"Crit Care"},{"key":"10.1016\/j.arbres.2018.03.006_bib0485","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1002\/j.2040-4603.2012.tb00449.x","article-title":"Airway-parenchymal interdependence","volume":"2","author":"Pare","year":"2012","journal-title":"Compr Physiol"},{"key":"10.1016\/j.arbres.2018.03.006_bib0490","doi-asserted-by":"crossref","DOI":"10.5935\/0103-507X.20170044","article-title":"What every intensivist should know about acute respiratory distress syndrome and diffuse alveolar damage?","author":"Rios","year":"2017","journal-title":"Rev Bras Ter Intensiva"},{"key":"10.1016\/j.arbres.2018.03.006_bib0495","first-page":"24","article-title":"Acute respiratory distress syndrome mimics: the role of lung biopsy","volume":"23","author":"Aublanc","year":"2017","journal-title":"Curr Opin Crit Care"},{"key":"10.1016\/j.arbres.2018.03.006_bib0500","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1378\/chest.15-0076","article-title":"Which patients with ARDS benefit from lung biopsy?","volume":"148","author":"Palakshappa","year":"2015","journal-title":"Chest"},{"key":"10.1016\/j.arbres.2018.03.006_bib0505","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1007\/s00134-016-4324-5","article-title":"Diagnostic workup for ARDS patients","volume":"42","author":"Papazian","year":"2016","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0510","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S2213-2600(14)70097-9","article-title":"Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials","volume":"2","author":"Calfee","year":"2014","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0515","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1164\/rccm.201603-0645OC","article-title":"Acute respiratory distress syndrome subphenotypes respond differently to randomized fluid management strategy","volume":"195","author":"Famous","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0520","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1164\/rccm.201512-2544CP","article-title":"Toward smarter lumping and smarter splitting: rethinking strategies for sepsis and acute respiratory distress syndrome clinical trial design","volume":"194","author":"Prescott","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0525","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1399-6576.1980.tb01541.x","article-title":"In vivo lung lavage as an experimental model of the respiratory distress syndrome","volume":"24","author":"Lachmann","year":"1980","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.arbres.2018.03.006_bib0530","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1164\/ajrccm.155.1.9001330","article-title":"Surfactant dysfunction makes lungs vulnerable to repetitive collapse and reexpansion","volume":"155","author":"Taskar","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0535","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1164\/rccm.200506-1006OC","article-title":"Atelectasis causes alveolar injury in nonatelectatic lung regions","volume":"174","author":"Tsuchida","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0540","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1152\/japplphysiol.00805.2007","article-title":"Cytokine release, small airway injury, and parenchymal damage during mechanical ventilation in normal open-chest rats","volume":"104","author":"D\u2019Angelo","year":"2008","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.arbres.2018.03.006_bib0545","doi-asserted-by":"crossref","first-page":"R4","DOI":"10.1186\/cc9401","article-title":"Small airway remodeling in acute respiratory distress syndrome: a study in autopsy lung tissue","volume":"15","author":"Morales","year":"2011","journal-title":"Crit Care"},{"key":"10.1016\/j.arbres.2018.03.006_bib0550","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcrc.2012.05.013","article-title":"Expression of acute-phase cytokines, surfactant proteins, and epithelial apoptosis in small airways of human acute respiratory distress syndrome","volume":"28","author":"Pires-Neto","year":"2013","journal-title":"J Crit Care"},{"key":"10.1016\/j.arbres.2018.03.006_bib0555","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.arbr.2015.02.001","article-title":"Cryobiopsy in the diagnosis of diffuse interstitial lung disease: yield and cost-effectiveness analysis","volume":"51","author":"Hernandez-Gonzalez","year":"2015","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.arbres.2018.03.006_bib0560","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.arbr.2015.02.033","article-title":"Transbronchial cryobiopsy in interstitial lung disease: advantageous costs to benefits ratio","volume":"51","author":"Montero Fernandez","year":"2015","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.arbres.2018.03.006_bib0565","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/MCP.0000000000000272","article-title":"Transbronchial cryobiopsy in diffuse parenchymal lung diseases","volume":"22","author":"Poletti","year":"2016","journal-title":"Curr Opin Pulm Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0570","doi-asserted-by":"crossref","first-page":"e86716","DOI":"10.1371\/journal.pone.0086716","article-title":"Transbronchial lung cryobiopsy in the diagnosis of fibrotic interstitial lung diseases","volume":"9","author":"Casoni","year":"2014","journal-title":"PLOS ONE"},{"key":"10.1016\/j.arbres.2018.03.006_bib0575","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.chest.2016.09.002","article-title":"Transbronchial cryobiopsy in diffuse parenchymal lung disease: retrospective analysis of 74 cases","volume":"151","author":"Ussavarungsi","year":"2017","journal-title":"Chest"},{"key":"10.1016\/j.arbres.2018.03.006_bib0580","doi-asserted-by":"crossref","first-page":"1274099","DOI":"10.1080\/20018525.2016.1274099","article-title":"Introduction of cryobiopsies in the diagnostics of interstitial lung diseases \u2013 experiences in a referral center","volume":"4","author":"Kronborg-White","year":"2017","journal-title":"Eur Clin Respir J"},{"key":"10.1016\/j.arbres.2018.03.006_bib0585","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1111\/resp.12322","article-title":"Diagnostic yield of transbronchial cryobiopsy in interstitial lung disease: a randomized trial","volume":"19","author":"Pajares","year":"2014","journal-title":"Respirology"},{"key":"10.1016\/j.arbres.2018.03.006_bib0590","first-page":"215","article-title":"Safety and diagnostic yield of transbronchial lung cryobiopsy in diffuse parenchymal lung diseases: a comparative study versus video-assisted thoracoscopic lung biopsy and a systematic review of the literature","volume":"91","author":"Ravaglia","year":"2016","journal-title":"Respir Int Rev Thorac Dis"},{"key":"10.1016\/j.arbres.2018.03.006_bib0595","doi-asserted-by":"crossref","first-page":"700","DOI":"10.4187\/respcare.04488","article-title":"Diagnostic yield and safety of cryoprobe transbronchial lung biopsy in diffuse parenchymal lung diseases: systematic review and meta-analysis","volume":"61","author":"Dhooria","year":"2016","journal-title":"Respir Care"},{"key":"10.1016\/j.arbres.2018.03.006_bib0600","doi-asserted-by":"crossref","DOI":"10.1513\/AnnalsATS.201610-829OC","article-title":"High complication rate after introduction of transbronchial cryobiopsy into clinical practice at an academic medical center","author":"DiBardino","year":"2017","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.arbres.2018.03.006_bib0605","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1136\/thx.2008.101493","article-title":"RAGE: a biomarker for acute lung injury","volume":"63","author":"Griffiths","year":"2008","journal-title":"Thorax"},{"key":"10.1016\/j.arbres.2018.03.006_bib0610","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1097\/01.ccm.0000435669.60811.24","article-title":"Plasma biomarkers for acute respiratory distress syndrome: a systematic review and meta-analysis","volume":"42","author":"Terpstra","year":"2014","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0615","first-page":"205","article-title":"Biomarkers in acute lung injury translational research","volume":"159","author":"Bhargava","year":"2012","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0620","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ccc.2011.04.001","article-title":"Biomarkers in acute lung injury \u2013 marking forward progress","volume":"27","author":"Barnett","year":"2011","journal-title":"Crit Care Clin"},{"key":"10.1016\/j.arbres.2018.03.006_bib0625","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1186\/1741-7015-9-132","article-title":"Biomarkers of acute lung injury: worth their salt?","volume":"9","author":"Proudfoot","year":"2011","journal-title":"BMC Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0630","doi-asserted-by":"crossref","first-page":"345","DOI":"10.5858\/arpa.2015-0519-RA","article-title":"Acute lung injury: a clinical and molecular review","volume":"140","author":"Butt","year":"2016","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0635","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1586\/17476348.2014.924073","article-title":"Biomarkers in acute respiratory distress syndrome: from pathobiology to improving patient care","volume":"8","author":"Walter","year":"2014","journal-title":"Expert Rev Respir Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0640","first-page":"102","article-title":"Characteristics of microRNAs and their potential relevance for the diagnosis and therapy of the acute respiratory distress syndrome: from bench to bedside translational research","volume":"169","author":"Cardinal-Fernandez","year":"2016","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0645","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.medin.2016.08.007","article-title":"Translational research in acute respiratory distress syndrome","volume":"41","author":"Cardinal-Fernandez","year":"2017","journal-title":"Medicina intensiva\/Sociedad Espanola de Medicina Intensiva y Unidades Coronarias"},{"key":"10.1016\/j.arbres.2018.03.006_bib0650","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1471-2466-10-6","article-title":"Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients","volume":"10","author":"Determann","year":"2010","journal-title":"BMC Pulm Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0655","doi-asserted-by":"crossref","first-page":"L855","DOI":"10.1152\/ajplung.00321.2014","article-title":"Association between early airway damage-associated molecular patterns and subsequent bacterial infection in patients with inhalational and burn injury","volume":"308","author":"Maile","year":"2015","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.arbres.2018.03.006_bib0660","doi-asserted-by":"crossref","first-page":"R72","DOI":"10.1186\/cc6911","article-title":"Effects of salbutamol on exhaled breath condensate biomarkers in acute lung injury: prospective analysis","volume":"12","author":"Roca","year":"2008","journal-title":"Crit Care"},{"key":"10.1016\/j.arbres.2018.03.006_bib0665","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.rmed.2010.01.013","article-title":"Mechanical ventilation induces changes in exhaled breath condensate of patients without lung injury","volume":"104","author":"Roca","year":"2010","journal-title":"Respir Med"},{"key":"10.1016\/j.arbres.2018.03.006_bib0670","first-page":"72","article-title":"Non-invasive detection of pulmonary pathogens in ventilator-circuit filters by PCR","volume":"4","author":"Isaacs","year":"2012","journal-title":"Am J Transl Res"},{"key":"10.1016\/j.arbres.2018.03.006_bib0675","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1378\/chest.14-1687","article-title":"A pilot study of the noninvasive assessment of the lung microbiota as a potential tool for the early diagnosis of ventilator-associated pneumonia","volume":"147","author":"May","year":"2015","journal-title":"Chest"},{"key":"10.1016\/j.arbres.2018.03.006_bib0680","article-title":"Novel method for non-invasive sampling of the distal airspace in acute respiratory distress syndrome","author":"McNeil","year":"2017","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Archivos de Bronconeumolog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300289618301480?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300289618301480?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:37:29Z","timestamp":1759531049000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300289618301480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":68,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S0300289618301480"],"URL":"https:\/\/doi.org\/10.1016\/j.arbres.2018.03.006","relation":{},"ISSN":["0300-2896"],"issn-type":[{"type":"print","value":"0300-2896"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Airway Pathological Alterations Selectively Associated With Acute Respiratory Distress Syndrome and Diffuse Alveolar Damage \u2013 Narrative Review","name":"articletitle","label":"Article Title"},{"value":"Archivos de Bronconeumolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arbres.2018.03.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 SEPAR. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}