{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T07:56:19Z","timestamp":1793692579330,"version":"4.5.1"},"reference-count":20,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archivos de Bronconeumolog\u00eda"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.arbres.2023.05.013","type":"journal-article","created":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T15:19:50Z","timestamp":1685632790000},"page":"497-501","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Respiratory Center Function and Its Impact in Obesity Hypoventilation Syndrome Treatment"],"prefix":"10.1016","volume":"59","author":[{"given":"In\u00e9s","family":"Ruiz \u00c1lvarez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram\u00f3n","family":"Fern\u00e1ndez \u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Rubinos Cuadrado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"V\u00e1zquez L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Garc\u00eda Clemente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arbres.2023.05.013_bib0105","first-page":"1347","article-title":"Obesity hypoventilation syndrome: a state-of-the-art review historical perspective definition epidemiology clinical presentation and diagnosis morbidity and mortality quality of life morbidity mortality pathophysiology the excessive load on the respirator","volume":"55","author":"Mokhlesi","year":"2010","journal-title":"Respir Care"},{"key":"10.1016\/j.arbres.2023.05.013_bib0110","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.amjmed.2005.03.042","article-title":"The obesity hypoventilation syndrome","volume":"118","author":"Olson","year":"2005","journal-title":"Am J Med"},{"key":"10.1016\/j.arbres.2023.05.013_bib0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1183\/16000617.0097-2018","article-title":"Obesity hypoventilation syndrome","volume":"28","author":"Masa","year":"2019","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.arbres.2023.05.013_bib0120","doi-asserted-by":"crossref","first-page":"E6","DOI":"10.1164\/rccm.201905-1071ST","article-title":"Evaluation and management of obesity hypoventilation syndrome an official American Thoracic Society clinical practice guideline","volume":"200","author":"Mokhlesi","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.arbres.2023.05.013_bib0125","series-title":"Princ. Pract. Sleep Med.","first-page":"1416","article-title":"Diagnosis and management of obesity hypoventilation syndrome","author":"Mokhlesi","year":"2017"},{"key":"10.1016\/j.arbres.2023.05.013_bib0130","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.ccm.2009.05.004","article-title":"The pickwickian syndrome-obesity hypoventilation syndrome","volume":"30","author":"Littleton","year":"2009","journal-title":"Clin Chest Med"},{"key":"10.1016\/j.arbres.2023.05.013_bib0135","first-page":"143","article-title":"Diagn\u00f3stico y tratamiento del s\u00edndrome de apneas-hipopneas del sue\u00f1o","volume":"47","author":"Lloberes","year":"2011","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.arbres.2023.05.013_bib0140","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.chest.2020.03.068","article-title":"Long-term noninvasive ventilation in obesity hypoventilation syndrome without severe OSA: the pickwick randomized controlled trial","volume":"158","author":"Masa","year":"2020","journal-title":"Chest"},{"key":"10.1016\/j.arbres.2023.05.013_bib0145","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1378\/chest.120.2.369","article-title":"The obesity-hypoventilation syndrome revisited: a prospective study of 34 consecutive cases","volume":"120","author":"Kessler","year":"2001","journal-title":"Chest"},{"key":"10.1016\/j.arbres.2023.05.013_bib0150","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1016\/S0140-6736(18)32978-7","article-title":"Long-term clinical effectiveness of continuous positive airway pressure therapy versus non-invasive ventilation therapy in patients with obesity hypoventilation syndrome: a multicentre, open-label, randomised controlled trial","volume":"393","author":"Masa","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.arbres.2023.05.013_bib0155","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1513\/pats.200708-122MG","article-title":"Assessment and management of patients with obesity hypoventilation syndrome","volume":"5","author":"Mokhlesi","year":"2008","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.arbres.2023.05.013_bib0160","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.chest.2017.06.036","article-title":"Initiation of noninvasive ventilation for sleep related hypoventilation disorders: advanced modes and devices","volume":"153","author":"Selim","year":"2018","journal-title":"Chest"},{"key":"10.1016\/j.arbres.2023.05.013_bib0165","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1183\/09031936.00059508","article-title":"Grading obesity hypoventilation syndrome severity","volume":"32","author":"Cabrera Lacalzada","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.arbres.2023.05.013_bib0170","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.arbres.2018.03.023","article-title":"Hypercapnia response in patients with obesity-hypoventilation syndrome treated with non-invasive ventilation at home","volume":"54","author":"Fern\u00e1ndez \u00c1lvarez","year":"2018","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.arbres.2023.05.013_bib0175","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"37","author":"Ponikowski","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.arbres.2023.05.013_bib0180","first-page":"20","article-title":"A clinical method for assessing the ventilatory response to carbon dioxide","volume":"16","author":"Read","year":"1967","journal-title":"Aust Ann Med"},{"key":"10.1016\/j.arbres.2023.05.013_bib0011","first-page":"53","article-title":"Efficacy of bilevel ventilatory support in the treatment of stable patients with obesity hypoventilation syndrome: systematic review and meta-analysis","author":"Royer","year":"2018","journal-title":"Sleep Med"},{"key":"10.1016\/j.arbres.2023.05.013_bib0190","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/resp.13704","article-title":"Obesity hypoventilation syndrome treated with non-invasive ventilation: is a switch to CPAP therapy feasible?","volume":"25","author":"Arellano-Maric","year":"2020","journal-title":"Respirology"},{"key":"10.1016\/j.arbres.2023.05.013_bib0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12890-017-0391-9","article-title":"Switch of noninvasive ventilation (NIV) to continuous positive airway pressure (CPAP) in patients with obesity hypoventilation syndrome: a pilot study","volume":"17","author":"Orfanos","year":"2017","journal-title":"BMC Pulm Med"},{"key":"10.1016\/j.arbres.2023.05.013_bib0200","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.arbres.2021.05.019","article-title":"Effectiveness of CPAP vs. noninvasive ventilation based on disease severity in obesity hypoventilation syndrome and concomitant severe obstructive sleep apnea","volume":"58","author":"Masa","year":"2022","journal-title":"Arch Bronconeumol"}],"container-title":["Archivos de Bronconeumolog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300289623001710?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300289623001710?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:42:20Z","timestamp":1759531340000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300289623001710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S0300289623001710"],"URL":"https:\/\/doi.org\/10.1016\/j.arbres.2023.05.013","relation":{},"ISSN":["0300-2896"],"issn-type":[{"value":"0300-2896","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Respiratory Center Function and Its Impact in Obesity Hypoventilation Syndrome Treatment","name":"articletitle","label":"Article Title"},{"value":"Archivos de Bronconeumolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arbres.2023.05.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 SEPAR. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}