{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T18:08:58Z","timestamp":1780942138645,"version":"3.54.1"},"reference-count":40,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AG061824"],"award-info":[{"award-number":["AG061824"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011096","name":"Jazz Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011096","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016479","name":"Jazz Pharmaceuticals Inc Ewing","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016479","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archivos de Bronconeumolog\u00eda"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.arbres.2023.09.007","type":"journal-article","created":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T12:46:11Z","timestamp":1695127571000},"page":"805-812","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Recovery Mimicking \u201cIdeal\u201d CPAP Adherence Does Not Improve Wakefulness or Cognition in Chronic Murine Models of OSA: Effect of Wake-Promoting Agents"],"prefix":"10.1016","volume":"59","author":[{"given":"Mohammad","family":"Badran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clementine","family":"Puech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max B.","family":"Barrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra R.","family":"Runion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Gozal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arbres.2023.09.007_bib0205","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S2213-2600(19)30198-5","article-title":"Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis","volume":"7","author":"Benjafield","year":"2019","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0210","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.sleep.2014.01.009","article-title":"Insights into obstructive sleep apnea research","volume":"15","author":"Badran","year":"2014","journal-title":"Sleep Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0215","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.cger.2021.04.007","article-title":"Obstructive sleep apnea: cognitive outcomes","volume":"37","author":"Patel","year":"2021","journal-title":"Clin Geriatr Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0220","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1513\/AnnalsATS.202205-380ST","article-title":"The link between obstructive sleep apnea and neurocognitive impairment: an official American Thoracic Society workshop report","volume":"19","author":"Lal","year":"2022","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.arbres.2023.09.007_bib0225","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.3390\/jcm11092375","article-title":"Quality of life and excessive daytime sleepiness in adults with obstructive sleep apnea who are treated with multilevel surgery or adherent to continuous positive airway pressure","volume":"11","author":"Iannella","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0230","doi-asserted-by":"crossref","first-page":"690008","DOI":"10.3389\/fneur.2021.690008","article-title":"Excessive daytime sleepiness in obstructive sleep apnea patients treated with continuous positive airway pressure: data from the European sleep apnea database","volume":"12","author":"Bonsignore","year":"2021","journal-title":"Front Neurol"},{"key":"10.1016\/j.arbres.2023.09.007_bib0235","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.mayocp.2020.08.033","article-title":"Excessive daytime sleepiness: a clinical review","volume":"96","author":"Gandhi","year":"2021","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.arbres.2023.09.007_bib0240","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.clinthera.2016.02.004","article-title":"Effects of modafinil and armodafinil in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials","volume":"38","author":"Kuan","year":"2016","journal-title":"Clin Ther"},{"key":"10.1016\/j.arbres.2023.09.007_bib0245","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1183\/13993003.01509-2015","article-title":"Modafinil\/armodafinil in obstructive sleep apnoea: a systematic review and meta-analysis","volume":"47","author":"Chapman","year":"2016","journal-title":"Eur Respir J"},{"key":"10.1016\/j.arbres.2023.09.007_bib0250","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1097\/JCP.0000000000001085","article-title":"The efficacy of modafinil as a cognitive enhancer: a systematic review and meta-analysis","volume":"39","author":"Kredlow","year":"2019","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.arbres.2023.09.007_bib0255","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/s00213-009-1493-8","article-title":"Depression-like deficits in rats improved by subchronic modafinil","volume":"204","author":"Regenthal","year":"2009","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.arbres.2023.09.007_bib0260","doi-asserted-by":"crossref","first-page":"458","DOI":"10.5664\/jcsm.27935","article-title":"The long-term tolerability and efficacy of armodafinil in patients with excessive sleepiness associated with treated obstructive sleep apnea, shift work disorder, or narcolepsy: an open-label extension study","volume":"6","author":"Black","year":"2010","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0265","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1002\/pds.4642","article-title":"Modafinil and the risk of cardiovascular events: findings from three US claims databases","volume":"27","author":"Kaplan","year":"2018","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.arbres.2023.09.007_bib0270","doi-asserted-by":"crossref","first-page":"75","DOI":"10.2147\/NSS.S245020","article-title":"Profile of solriamfetol in the management of excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea: focus on patient selection and perspectives","volume":"13","author":"Abad","year":"2021","journal-title":"Nat Sci Sleep"},{"key":"10.1016\/j.arbres.2023.09.007_bib0275","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jpsychires.2022.08.018","article-title":"Solriamfetol treatment of excessive daytime sleepiness in participants with narcolepsy or obstructive sleep apnea with a history of depression","volume":"155","author":"Krystal","year":"2022","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.arbres.2023.09.007_bib0280","first-page":"46","article-title":"Solriamfetol improves chronic sleep fragmentation-induced increases in sleep propensity and ameliorates explicit memory in male mice","author":"Puech","year":"2023","journal-title":"Sleep"},{"key":"10.1016\/j.arbres.2023.09.007_bib0285","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.sleep.2023.04.007","article-title":"Solriamfetol enhances wakefulness and improves cognition and anxiety in a murine model of OSA","volume":"107","author":"Badran","year":"2023","journal-title":"Sleep Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0290","doi-asserted-by":"crossref","first-page":"100084","DOI":"10.1016\/j.nbscr.2022.100084","article-title":"Explicit memory, anxiety and depressive like behavior in mice exposed to chronic intermittent hypoxia, sleep fragmentation, or both during the daylight period","volume":"13","author":"Puech","year":"2022","journal-title":"Neurobiol Sleep Circadian Rhythms"},{"key":"10.1016\/j.arbres.2023.09.007_bib0295","doi-asserted-by":"crossref","first-page":"710435","DOI":"10.3389\/fpsyt.2021.710435","article-title":"Excessive daytime sleepiness in depression and obstructive sleep apnea: more than just an overlapping symptom","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.arbres.2023.09.007_bib0300","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s12955-020-01382-4","article-title":"Understanding the burden of illness of excessive daytime sleepiness associated with obstructive sleep apnea: a qualitative study","volume":"18","author":"Waldman","year":"2020","journal-title":"Health Qual Life Outcomes"},{"key":"10.1016\/j.arbres.2023.09.007_bib0305","doi-asserted-by":"crossref","first-page":"911996","DOI":"10.3389\/fneur.2022.911996","article-title":"Predictors of the efficacy for daytime sleepiness in patients with obstructive sleep apnea with continual positive airway pressure therapy: a meta-analysis of randomized controlled trials","volume":"13","author":"Li","year":"2022","journal-title":"Front Neurol"},{"key":"10.1016\/j.arbres.2023.09.007_bib0310","first-page":"31","article-title":"Investigation and management of residual sleepiness in CPAP-treated patients with obstructive sleep apnoea: the European view","author":"Craig","year":"2022","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.arbres.2023.09.007_bib0315","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1002\/jnr.23634","article-title":"Evidence of neurodegeneration in obstructive sleep apnea: relationship between obstructive sleep apnea and cognitive dysfunction in the elderly","volume":"93","author":"Daulatzai","year":"2015","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.arbres.2023.09.007_bib0320","doi-asserted-by":"crossref","first-page":"676","DOI":"10.7326\/M22-3473","article-title":"Comparative efficacy and safety of wakefulness-promoting agents for excessive daytime sleepiness in patients with obstructive sleep apnea: a systematic review and network meta-analysis","volume":"176","author":"Pitre","year":"2023","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0325","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/1471-2202-13-77","article-title":"Exogenous erythropoietin administration attenuates intermittent hypoxia-induced cognitive deficits in a murine model of sleep apnea","volume":"13","author":"Dayyat","year":"2012","journal-title":"BMC Neurosci"},{"key":"10.1016\/j.arbres.2023.09.007_bib0330","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1164\/rccm.200411-1564OC","article-title":"Inducible nitric oxide synthase in long-term intermittent hypoxia: hypersomnolence and brain injury","volume":"171","author":"Zhan","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0335","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/sleep\/27.2.194","article-title":"Long-term intermittent hypoxia in mice: protracted hypersomnolence with oxidative injury to sleep-wake brain regions","volume":"27","author":"Veasey","year":"2004","journal-title":"Sleep"},{"key":"10.1016\/j.arbres.2023.09.007_bib0340","doi-asserted-by":"crossref","first-page":"10060","DOI":"10.1523\/JNEUROSCI.0857-07.2007","article-title":"Selective loss of catecholaminergic wake active neurons in a murine sleep apnea model","volume":"27","author":"Zhu","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.arbres.2023.09.007_bib0345","first-page":"13","article-title":"Effects of sleep fragmentation on sleep and markers of inflammation in mice","volume":"64","author":"Trammell","year":"2014","journal-title":"Comp Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0350","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1513\/AnnalsATS.202006-696FR","article-title":"Excessive daytime sleepiness in obstructive sleep apnea. Mechanisms and clinical management","volume":"18","author":"Lal","year":"2021","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.arbres.2023.09.007_bib0355","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.chest.2021.02.033","article-title":"Randomized controlled trial of solriamfetol for excessive daytime sleepiness in OSA: an analysis of subgroups adherent or nonadherent to OSA treatment","volume":"160","author":"Schweitzer","year":"2021","journal-title":"Chest"},{"key":"10.1016\/j.arbres.2023.09.007_bib0360","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.5664\/jcsm.9610","article-title":"Indirect treatment comparison of solriamfetol, modafinil, and armodafinil for excessive daytime sleepiness in obstructive sleep apnea","volume":"17","author":"Ronnebaum","year":"2021","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0365","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1164\/rccm.201801-0204PP","article-title":"Obstructive sleep apnea and the risk of cognitive decline in older adults","volume":"199","author":"Gosselin","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0370","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1513\/AnnalsATS.202002-136OC","article-title":"Effects of solriamfetol on quality-of-life measures from a 12-week phase 3 randomized controlled trial","volume":"17","author":"Weaver","year":"2020","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.arbres.2023.09.007_bib0375","first-page":"55718","article-title":"Novel object recognition test for the investigation of learning and memory in mice","volume":"126","author":"Lueptow","year":"2017","journal-title":"J Vis Exp"},{"key":"10.1016\/j.arbres.2023.09.007_bib0380","first-page":"525","article-title":"Prevalence of depression and anxiety in obstructive sleep apnea","volume":"100","author":"Gharsalli","year":"2022","journal-title":"Tunis Med"},{"key":"10.1016\/j.arbres.2023.09.007_bib0385","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1038\/npp.2010.83","article-title":"Modulatory effects of modafinil on neural circuits regulating emotion and cognition","volume":"35","author":"Rasetti","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.arbres.2023.09.007_bib0390","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/cns.13218","article-title":"Chronic sleep fragmentation shares similar pathogenesis with neurodegenerative diseases: endosome\u2013autophagosome\u2013lysosome pathway dysfunction and microglia-mediated neuroinflammation","volume":"26","author":"Xie","year":"2020","journal-title":"CNS Neurosci Ther"},{"key":"10.1016\/j.arbres.2023.09.007_bib0395","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/jnc.12360","article-title":"Growth hormone releasing hormone (GHRH) signaling modulates intermittent hypoxia-induced oxidative stress and cognitive deficits in mouse","volume":"127","author":"Nair","year":"2013","journal-title":"J Neurochem"},{"key":"10.1016\/j.arbres.2023.09.007_bib0400","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1515\/jbcpp-2020-0021","article-title":"Nitric oxide mediates the antidepressant-like effect of modafinil in mouse forced swimming and tail suspension tests","volume":"32","author":"Omidi-Ardali","year":"2020","journal-title":"J Basic Clin Physiol Pharmacol"}],"container-title":["Archivos de Bronconeumolog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300289623003010?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300289623003010?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:43:14Z","timestamp":1759531394000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300289623003010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S0300289623003010"],"URL":"https:\/\/doi.org\/10.1016\/j.arbres.2023.09.007","relation":{},"ISSN":["0300-2896"],"issn-type":[{"value":"0300-2896","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recovery Mimicking \u201cIdeal\u201d CPAP Adherence Does Not Improve Wakefulness or Cognition in Chronic Murine Models of OSA: Effect of Wake-Promoting Agents","name":"articletitle","label":"Article Title"},{"value":"Archivos de Bronconeumolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arbres.2023.09.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 SEPAR. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}