{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:08:20Z","timestamp":1791950900822,"version":"4.3.4"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100015285","name":"Hebei Province Medical Science Research Key Project","doi-asserted-by":"publisher","award":["20240035"],"award-info":[{"award-number":["20240035"]}],"id":[{"id":"10.13039\/501100015285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Gerontology and Geriatrics"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.archger.2025.106094","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T07:33:08Z","timestamp":1763969588000},"page":"106094","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Association of gut microbiota and arginine-agmatine metabolism with postoperative delirium in elderly patients following lower limb fracture surgery: a prospective nested case-control study"],"prefix":"10.1016","volume":"142","author":[{"given":"Xinyu","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yv","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianli","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0010","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2022.2102878","article-title":"Microbiota-derived metabolites as drivers of gut-brain communication","volume":"14","author":"Ahmed","year":"2022","journal-title":"Gut Microbes"},{"key":"10.1016\/j.archger.2025.106094_bib0017","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.schres.2020.05.006","article-title":"Reduced blood agmatine level in early-onset schizophrenia","volume":"222","author":"Baytunca","year":"2020","journal-title":"Schizophrenia Research"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0036","article-title":"Microbiota dysbiosis and functional outcome in acute ischemic stroke patients","volume":"11","author":"Chang","year":"2021","journal-title":"Scientific Reports"},{"key":"10.1016\/j.archger.2025.106094_bib0001","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2022.1068278","article-title":"Postoperative delirium in geriatric patients with hip fractures","volume":"14","author":"Chen","year":"2022","journal-title":"Frontiers in Aging Neuroscience"},{"issue":"4","key":"10.1016\/j.archger.2025.106094_bib0051","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24043074","article-title":"Antibiotic-therapy-induced gut dysbiosis affecting gut microbiota-brain axis and cognition: Restoration by intake of probiotics and synbiotics","volume":"24","author":"Dahiya","year":"2023","journal-title":"International Journal of Molecular Sciences"},{"issue":"5","key":"10.1016\/j.archger.2025.106094_bib0040","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.2741\/3820","article-title":"Amino acid metabolism in intestinal bacteria: Links between gut ecology and host health","volume":"16","author":"Dai","year":"2011","journal-title":"Frontiers in Bioscience (Landmark Edition)"},{"issue":"133","key":"10.1016\/j.archger.2025.106094_bib0031","doi-asserted-by":"crossref","DOI":"10.3791\/56845","article-title":"Guided protocol for fecal microbial characterization by 16S rRNA-amplicon sequencing","author":"Di Segni","year":"2018","journal-title":"Journal of Visualized Experiments : JoVE"},{"issue":"4","key":"10.1016\/j.archger.2025.106094_bib0019","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1007\/s00702-017-1836-2","article-title":"Decreased plasma agmatine levels in autistic subjects","volume":"125","author":"Esnafoglu","year":"2018","journal-title":"Journal of Neural Transmission (Vienna, Austria : 1996)"},{"issue":"3","key":"10.1016\/j.archger.2025.106094_bib0021","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\"Mini-mental state\". A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"Journal of Psychiatric Research"},{"issue":"9","key":"10.1016\/j.archger.2025.106094_bib0016","doi-asserted-by":"crossref","first-page":"E3124","DOI":"10.1002\/brb3.3124","article-title":"Agmatine improves liver function, balance performance, and neuronal damage in a hepatic encephalopathy induced by bile duct ligation","volume":"13","author":"Ganjalikhan-Hakemi","year":"2023","journal-title":"Brain and Behavior"},{"key":"10.1016\/j.archger.2025.106094_bib0029","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.schres.2018.12.015","article-title":"l-arginine metabolism before and after 10 weeks of antipsychotic treatment in first-episode psychotic patients","volume":"206","author":"Garip","year":"2018","journal-title":"Schizophrenia Research"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0049","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1186\/s13054-018-2262-z","article-title":"Antimicrobial exposure and the risk of delirium in critically ill patients","volume":"22","author":"Grahl","year":"2018","journal-title":"Critical Care (London, England)"},{"key":"10.1016\/j.archger.2025.106094_bib0032","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2020.570210","article-title":"Metabolomic and lipidomic profiling of preoperative CSF in elderly hip fracture patients with postoperative delirium","volume":"12","author":"Han","year":"2020","journal-title":"Frontiers in Aging Neuroscience"},{"issue":"7867","key":"10.1016\/j.archger.2025.106094_bib0044","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/s41586-021-03707-9","article-title":"A metabolomics pipeline for the mechanistic interrogation of the gut microbiome","volume":"595","author":"Han","year":"2021","journal-title":"Nature"},{"issue":"15","key":"10.1016\/j.archger.2025.106094_bib0014","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.2174\/1389557523666230125104753","article-title":"Perspectives on agmatine neurotransmission in acute and chronic stressrelated conditions","volume":"23","author":"Hassanshahi","year":"2023","journal-title":"Mini Reviews in Medicinal Chemistry"},{"issue":"11","key":"10.1016\/j.archger.2025.106094_bib0022","doi-asserted-by":"crossref","DOI":"10.1002\/acr.25202","volume":"63","author":"Hawker","year":"2011","journal-title":"Arthritis Care & Research"},{"issue":"4","key":"10.1016\/j.archger.2025.106094_bib0043","doi-asserted-by":"crossref","DOI":"10.1111\/acel.14081","article-title":"l-arginine metabolism ameliorates age-related cognitive impairment by Amuc_1100-mediated gut homeostasis maintaining","volume":"23","author":"He","year":"2024","journal-title":"Aging Cell"},{"key":"10.1016\/j.archger.2025.106094_bib0030","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2022.944236","article-title":"Pre-operative status of gut microbiota predicts post-operative delirium in patients with gastric cancer","volume":"13","author":"Jiang","year":"2022","journal-title":"Frontiers in Psychiatry"},{"issue":"7","key":"10.1016\/j.archger.2025.106094_bib0055","doi-asserted-by":"crossref","DOI":"10.3390\/metabo12070616","article-title":"The influence of orthopedic surgery on circulating metabolite levels, and their associations with the incidence of postoperative delirium","volume":"12","author":"Jung","year":"2022","journal-title":"Metabolites"},{"key":"10.1016\/j.archger.2025.106094_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2024.102269","article-title":"Agmatine as a novel intervention for Alzheimer's disease: Pathological insights and cognitive benefits","volume":"96","author":"Katariya","year":"2024","journal-title":"Ageing Research Reviews"},{"key":"10.1016\/j.archger.2025.106094_bib0054","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.brainresbull.2020.04.013","article-title":"Agmatine ameliorates manifestation of depression-like behavior and hippocampal neuroinflammation in mouse model of Alzheimer's disease","volume":"160","author":"Kotagale","year":"2020","journal-title":"Brain Research Bulletin"},{"issue":"13","key":"10.1016\/j.archger.2025.106094_bib0042","doi-asserted-by":"crossref","DOI":"10.3390\/cells11132084","article-title":"Identification and characterization of a novel species of genus Akkermansia with metabolic health effects in a diet-induced obesity mouse model","volume":"11","author":"Kumar","year":"2022","journal-title":"Cells"},{"issue":"3","key":"10.1016\/j.archger.2025.106094_bib0027","first-page":"147","article-title":"Reversion of CAM for assisting the evaluation and diagnosis of delirium","author":"LI","year":"2003","journal-title":"Journal of Clinical Psychiatric Medicine"},{"key":"10.1016\/j.archger.2025.106094_bib0002","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2147\/CIA.S346954","article-title":"White-cell derived inflammatory biomarkers in prediction of postoperative delirium in elderly patients undergoing surgery for lower limb fracture under non-general anaesthesia","volume":"17","author":"Li","year":"2022","journal-title":"Clinical Interventions in Aging"},{"issue":"10","key":"10.1016\/j.archger.2025.106094_bib0011","doi-asserted-by":"crossref","first-page":"4123","DOI":"10.1038\/s41380-022-01569-9","article-title":"Multi-omics analyses of serum metabolome, gut microbiome and brain function reveal dysregulated microbiota-gut-brain axis in bipolar depression","volume":"27","author":"Li","year":"2022","journal-title":"Molecular Psychiatry"},{"issue":"2","key":"10.1016\/j.archger.2025.106094_bib0028","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/14737175.2021.1862650","article-title":"Polyamines serum levels in episodic and chronic migraine","volume":"21","author":"Lionetto","year":"2020","journal-title":"Expert Review of Neurotherapeutics"},{"key":"10.1016\/j.archger.2025.106094_bib0006","article-title":"Preoperative status of gut microbiota predicts postoperative delirium in patients with gastric cancer","volume":"13","author":"Liu","year":"2022","journal-title":"Frontiers in Psychiatry"},{"issue":"2","key":"10.1016\/j.archger.2025.106094_bib0009","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/SLA.0000000000005489","article-title":"Orthopedic surgery causes gut microbiome dysbiosis and intestinal barrier dysfunction in prodromal Alzheimer Disease patients: A prospective observational cohort study","volume":"276","author":"Liu","year":"2022","journal-title":"Annals of Surgery"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0026","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12871-023-02036-w","article-title":"Correlation and influencing factors of preoperative anxiety, postoperative pain, and delirium in elderly patients undergoing gastrointestinal cancer surgery","volume":"23","author":"Liu","year":"2023","journal-title":"BMC Anesthesiology"},{"key":"10.1016\/j.archger.2025.106094_bib0004","article-title":"The role of gut microbiota-gut-brain axis in perioperative neurocognitive dysfunction","volume":"13","author":"Lu","year":"2022","journal-title":"Frontiers in Pharmacology"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0041","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2348441","article-title":"Commensal microbiota-derived metabolite agmatine triggers inflammation to promote colorectal tumorigenesis","volume":"16","author":"Lu","year":"2024","journal-title":"Gut Microbes"},{"issue":"2","key":"10.1016\/j.archger.2025.106094_bib0034","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1111\/jgs.18104","article-title":"Postoperative delirium after transcatheter aortic valve replacement: An updated systematic review and meta-analysis","volume":"71","author":"Ma","year":"2023","journal-title":"Journal of the American Geriatrics Society"},{"key":"10.1016\/j.archger.2025.106094_bib0039","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jpsychires.2024.01.036","article-title":"Associations of gut microbiota alterations with clinical, metabolic, and immune-inflammatory characteristics of chronic schizophrenia","volume":"171","author":"Misiak","year":"2024","journal-title":"Journal of Psychiatric Research"},{"issue":"5","key":"10.1016\/j.archger.2025.106094_bib0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3002125","article-title":"Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe eggerthella lenta","volume":"21","author":"Noecker","year":"2023","journal-title":"PLoS Biology"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0052","doi-asserted-by":"crossref","DOI":"10.1007\/s00248-022-02081-x","article-title":"Human gut microbiota and drug metabolism","volume":"86","author":"Pant","year":"2022","journal-title":"Microbial Ecology"},{"key":"10.1016\/j.archger.2025.106094_bib0053","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176884","article-title":"Agmatine modulation of gut-brain axis alleviates dysbiosis-induced depression-like behavior in rats","volume":"981","author":"Rahangdale","year":"2024","journal-title":"European Journal of Pharmacology"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0033","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s13018-020-02127-1","article-title":"Risk factors of postoperative delirium in the knee and hip replacement patients: A systematic review and meta-analysis","volume":"16","author":"Rong","year":"2021","journal-title":"Journal of Orthopaedic Surgery and Research"},{"key":"10.1016\/j.archger.2025.106094_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2023.102056","article-title":"Neuroprotection by agmatine: Possible involvement of the gut microbiome?","volume":"91","author":"Saha","year":"2023","journal-title":"Ageing Research Reviews"},{"key":"10.1016\/j.archger.2025.106094_bib0048","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105840","article-title":"The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders","volume":"172","author":"Soca\u0142a","year":"2021","journal-title":"Pharmacological Research"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0035","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s40168-017-0242-1","article-title":"New evidences on the altered gut microbiota in autism spectrum disorders","volume":"5","author":"Strati","year":"2017","journal-title":"Microbiome"},{"key":"10.1016\/j.archger.2025.106094_bib0005","article-title":"Gut microbiota in perioperative neurocognitive disorders: Current evidence and future directions","volume":"14","author":"Sun","year":"2023","journal-title":"Frontiers in Immunology"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0003","article-title":"Evidence-based strategies to reduce the incidence of postoperative delirium: A narrative review","volume":"77","author":"Swarbrick","year":"2022","journal-title":"Anaesthesia"},{"key":"10.1016\/j.archger.2025.106094_bib0050","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.2147\/CIA.S139163","article-title":"Gut microbiota, cognitive frailty and dementia in older individuals: A systematic review","volume":"13","author":"Ticinesi","year":"2018","journal-title":"Clinical Interventions in Aging"},{"key":"10.1016\/j.archger.2025.106094_bib0038","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.parkreldis.2021.11.017","article-title":"Gut microbiome in Parkinson's disease: New insights from meta-analysis","volume":"94","author":"Toh","year":"2022","journal-title":"Parkinsonism & Related Disorders"},{"issue":"15","key":"10.1016\/j.archger.2025.106094_bib0047","doi-asserted-by":"crossref","first-page":"5893","DOI":"10.1073\/pnas.1301442110","article-title":"Substrate selectivity in arginine-dependent acid resistance in enteric bacteria","volume":"110","author":"Tsai","year":"2013","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"3","key":"10.1016\/j.archger.2025.106094_bib0046","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/hel.12115","article-title":"Characterization of the arginine decarboxylase gene (ORF HP0422, speA) involved in acid tolerance in Helicobacter pylori","volume":"19","author":"Valenzuela","year":"2014","journal-title":"Helicobacter."},{"issue":"2","key":"10.1016\/j.archger.2025.106094_bib0024","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/aje\/kww177","article-title":"Comparison of collection methods for fecal samples in microbiome studies","volume":"185","author":"Vogtmann","year":"2016","journal-title":"The American Journal of Epidemiology"},{"key":"10.1016\/j.archger.2025.106094_bib0025","article-title":"The effect of parecoxib sodium on postoperative delirium in elderly patients with hip arthroplasty","volume":"14","author":"Wang","year":"2023","journal-title":"Frontiers in Pharmacology"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0008","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1186\/s12974-024-03220-6","article-title":"Preoperative gut microbiota of POCD patients induces pre- and postoperative cognitive impairment and systemic inflammation in rats","volume":"21","author":"Wei","year":"2024","journal-title":"Journal of Neuroinflammation"},{"issue":"2","key":"10.1016\/j.archger.2025.106094_bib0037","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1080\/1040841X.2022.2044286","article-title":"The role of the probiotic Akkermansia muciniphila in brain functions: Insights underpinning therapeutic potential","volume":"49","author":"Xu","year":"2023","journal-title":"Critical Reviews in Microbiology"},{"issue":"2","key":"10.1016\/j.archger.2025.106094_bib0018","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1080\/13651501.2019.1569237","article-title":"Evaluation of plasma agmatine level and its metabolic pathway in patients with bipolar disorder during manic episode and remission period","volume":"23","author":"Y\u0131lmaz","year":"2019","journal-title":"International Journal of Psychiatry in Clinical Practice"},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0020","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/ana.26918","article-title":"Mitochondrial dysfunction of peripheral platelets as a predictive biomarker for postoperative delirium in elderly patients","volume":"96","author":"Yang","year":"2024","journal-title":"Annals of Neurology"},{"issue":"15","key":"10.1016\/j.archger.2025.106094_bib0023","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.124.035837","article-title":"Plasma polyamines and short-term adverse outcomes among patients with ischemic stroke: A prospective cohort study","volume":"13","author":"Yang","year":"2024","journal-title":"Journal of the American Heart Association"},{"key":"10.1016\/j.archger.2025.106094_bib0013","doi-asserted-by":"crossref","DOI":"10.1007\/s10753-024-02139-7","article-title":"The neuroprotective effects of Agmatine on Parkinson's Disease: Focus on oxidative stress, inflammation and molecular mechanisms","author":"Zamanian","year":"2024","journal-title":"Inflammation."},{"issue":"1","key":"10.1016\/j.archger.2025.106094_bib0007","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/s41398-023-02450-1","article-title":"The association between gut microbiota and postoperative delirium in patients","volume":"13","author":"Zhang","year":"2023","journal-title":"Translational Psychiatry"}],"container-title":["Archives of Gerontology and Geriatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167494325003516?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167494325003516?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T12:31:23Z","timestamp":1778502683000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167494325003516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":55,"alternative-id":["S0167494325003516"],"URL":"https:\/\/doi.org\/10.1016\/j.archger.2025.106094","relation":{},"ISSN":["0167-4943"],"issn-type":[{"value":"0167-4943","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of gut microbiota and arginine-agmatine metabolism with postoperative delirium in elderly patients following lower limb fracture surgery: a prospective nested case-control study","name":"articletitle","label":"Article Title"},{"value":"Archives of Gerontology and Geriatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.archger.2025.106094","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106094"}}