{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:41:30Z","timestamp":1790613690636,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Oral Biology"],"published-print":{"date-parts":[[2004,6]]},"DOI":"10.1016\/j.archoralbio.2004.01.010","type":"journal-article","created":{"date-parts":[[2004,4,9]],"date-time":"2004-04-09T05:21:41Z","timestamp":1081488101000},"page":"435-442","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":55,"title":["Delayed tooth eruption and suppressed osteoclast number in the eruption pathway of heterozygous Runx2\/Cbfa1 knockout mice"],"prefix":"10.1016","volume":"49","author":[{"given":"Shuichi","family":"Yoda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoto","family":"Suda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Kitahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihisa","family":"Komori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimie","family":"Ohyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.archoralbio.2004.01.010_BIB1","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0092-8674(00)80258-5","article-title":"Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts","volume":"89","author":"Komori","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB2","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0092-8674(00)80259-7","article-title":"Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development","volume":"89","author":"Otto","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB3","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S0092-8674(00)80260-3","article-title":"Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia","volume":"89","author":"Mundlos","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB4","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/ng0797-307","article-title":"Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2\/CBFA1 in cleidocranial dysplasia","volume":"16","author":"Lee","year":"1997","journal-title":"Nat Genet"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB5","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1086\/302622","article-title":"Mutation analysis of core binding factor A1 in patients with cleidocranial dysplasia","volume":"65","author":"Quack","year":"1999","journal-title":"Am. J. Hum Genet"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB6","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s007740170030","article-title":"Identification of a novel frameshift mutation (383insT) in the RUNX2 (PEBP2 alpha\/CBFA1\/AML3) gene in a Japanese patient with cleidocranial dysplasia","volume":"19","author":"Goseki-Sone","year":"2001","journal-title":"J. Bone Miner Metab"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB7","first-page":"212","article-title":"Histological observations of teeth and peridental tissues in cleidocranial dysplasia imply increased activity of odontogenic epithelium and abnormal bone remodelling","volume":"15","author":"Lukinmaa","year":"1995","journal-title":"J. Craniofac. Genet Dev. Biol."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB8","first-page":"121","article-title":"A case of Japanese cleidocranial dysplasia with a CBFA1 frameshift mutation","volume":"20","author":"Yokozeki","year":"2000","journal-title":"J. Craniofac. Genet Dev. Biol."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB9","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1600-0714.1990.tb00803.x","article-title":"Development of the dentition in cleidocranial dysplasia","volume":"19","author":"Jensen","year":"1990","journal-title":"J. Oral. Pathol. Med."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB10","unstructured":"Ten Cate AR. Physiologic tooth movement, eruption and shedding. In: Ten Cate AP, editor. Oral histology, development, structure and function, 5th ed. St. Louis: Mosby, 1998; p. 289\u2013314."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB11","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1177\/154411130201300403","article-title":"Cellular, molecular, and genetic determinants of tooth eruption","volume":"13","author":"Wise","year":"2002","journal-title":"Crit. Rev. Oral Biol. Med."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB12","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/aja.1001680303","article-title":"The cytology of the dental follicle and adjacent alveolar bone during tooth eruption in the dog","volume":"168","author":"Marks","year":"1983","journal-title":"Am. J. Anat."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB13","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1034\/j.1600-0722.2000.108004297.x","article-title":"Delay of tooth eruption in null mice devoid of the type I IL-1R gene","volume":"108","author":"Huang","year":"2000","journal-title":"Eur J. Oral. Sci."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB14","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1177\/35.2.3540104","article-title":"Tartrate-resistant acid phosphatase in bone and cartilage following decalcification and cold-embedding in plastic","volume":"35","author":"Cole","year":"1987","journal-title":"J. Histochem. Cytochem"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB15","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/jbmr.5650020617","article-title":"Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee","volume":"2","author":"Parfitt","year":"1987","journal-title":"J. Bone Miner Res"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB16","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1242\/dev.126.13.2911","article-title":"Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice","volume":"126","author":"D\u2019Souza","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB17","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1006\/bbrc.1998.9643","article-title":"Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF)","volume":"252","author":"Gao","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB18","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.1073\/pnas.95.7.3597","article-title":"Osteoclast differentiation factor is a ligand for osteoprotegerin\/osteoclastogenesis- inhibitory factor and is identical to TRANCE\/RANKL","volume":"95","author":"Yasuda","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB19","doi-asserted-by":"crossref","unstructured":"Enomoto H, Shiojiri S, Hoshi K, Furuichi T, Fukuyama R, Yoshida CA, et al. Induction of osteoclast differentiation by Runx2 through RANKL and OPG regulation and partial rescue of osteoclastogenesis in Runx2-\/- mice by RANKL transgene. J Biol Chem 2003;278:23971\u20137.","DOI":"10.1074\/jbc.M302457200"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB20","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0092-8674(00)80209-3","article-title":"Osteoprotegerin: a novel secreted protein involved in the regulation of bone density","volume":"89","author":"Simonet","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB21","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0167-4781(99)00032-9","article-title":"Promoter structure of mouse RANKL\/TRANCE\/OPGL\/ODF gene","volume":"1445","author":"Kitazawa","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB22","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S8756-3282(01)00692-5","article-title":"Cbfa1 does not regulate RANKL gene activity in stromal\/osteoblastic cells","volume":"30","author":"O\u2019Brien","year":"2002","journal-title":"Bone"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB23","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1177\/00220345890680021001","article-title":"Changes in the tartrate-resistant acid phosphatase cell population in dental follicles and bony crypts of rat molars during tooth eruption","volume":"68","author":"Wise","year":"1989","journal-title":"J. Dent Res."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB24","doi-asserted-by":"crossref","first-page":"11846","DOI":"10.1073\/pnas.95.20.11846","article-title":"Parathyroid hormone- related protein is required for tooth eruption","volume":"95","author":"Philbrick","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB25","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S8756-3282(03)00172-8","article-title":"Development of a novel mouse osteoclast culture system using mandibular body and erupting teeth","volume":"33","author":"Suda","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB26","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1016\/S0021-9258(19)83739-0","article-title":"Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal","volume":"237","author":"Cohen","year":"1962","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB27","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1046\/j.0909-8836.1998.eos106307.x","article-title":"Secretion of CSF-1 and its inhibition in rat dental follicle cells: implications for tooth eruption","volume":"106","author":"Grier","year":"1998","journal-title":"Eur. J. Oral. Sci."},{"key":"10.1016\/j.archoralbio.2004.01.010_BIB28","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0003-9969(03)00135-3","article-title":"Tooth eruption and cementum formation in the Runx2\/Cbfa1 heterozygous mouse","volume":"48","author":"Zou","year":"2003","journal-title":"Arch. Oral. Biol."}],"container-title":["Archives of Oral Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996904000196?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996904000196?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T06:30:30Z","timestamp":1757745030000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003996904000196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["S0003996904000196"],"URL":"https:\/\/doi.org\/10.1016\/j.archoralbio.2004.01.010","relation":{},"ISSN":["0003-9969"],"issn-type":[{"value":"0003-9969","type":"print"}],"subject":[],"published":{"date-parts":[[2004,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Delayed tooth eruption and suppressed osteoclast number in the eruption pathway of heterozygous Runx2\/Cbfa1 knockout mice","name":"articletitle","label":"Article Title"},{"value":"Archives of Oral Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.archoralbio.2004.01.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}