{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:13:38Z","timestamp":1777601618764,"version":"3.51.4"},"reference-count":39,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Oral Biology"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1016\/j.archoralbio.2011.03.009","type":"journal-article","created":{"date-parts":[[2011,4,19]],"date-time":"2011-04-19T18:40:52Z","timestamp":1303238452000},"page":"1162-1169","source":"Crossref","is-referenced-by-count":18,"title":["Interaction between tumour necrosis factor-\u03b1 gene polymorphisms and substance use on risk of betel quid-related oral and pharyngeal squamous cell carcinoma in Taiwan"],"prefix":"10.1016","volume":"56","author":[{"given":"Cheng-Mei","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Yi","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Ten","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hung-Chih","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sau-Tung","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao-Chuan","family":"Chi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Hsiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Yiing","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina Jen-Chia","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Chen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao-Dung","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luo-Ping","family":"Ger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.archoralbio.2011.03.009_bib0005","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1600-0528.2005.00251.x","article-title":"Strengthening the prevention of oral cancer: the WHO perspective","volume":"33","author":"Petersen","year":"2005","journal-title":"Community Dent Oral Epidemiol"},{"key":"10.1016\/j.archoralbio.2011.03.009_bib0010","series-title":"Bureau of health promotion annual report 2009","author":"PROMOTION BOH","year":"2009"},{"issue":"8","key":"10.1016\/j.archoralbio.2011.03.009_bib0015","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s00432-008-0360-z","article-title":"Gene expression polymorphisms of interleukins-1 beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma","volume":"134","author":"Vairaktaris","year":"2008","journal-title":"J Cancer Res Clin Oncol"},{"issue":"6","key":"10.1016\/j.archoralbio.2011.03.009_bib0020","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.oraloncology.2005.08.005","article-title":"Oral submucous fibrosis: review on aetiology and pathogenesis","volume":"42","author":"Tilakaratne","year":"2006","journal-title":"Oral Oncol"},{"key":"10.1016\/j.archoralbio.2011.03.009_bib0025","unstructured":"IARC. Betel-quid and areca-nut chewing and some areca-nut derived nitrosamines. In IARC monographs on the evaluation of carcinogenic risks to humans. International Agency for Research on Cancer, vol. 85. Lyon, France; 2004, p. 230\u2013239."},{"issue":"8","key":"10.1016\/j.archoralbio.2011.03.009_bib0030","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1093\/carcin\/bgg083","article-title":"Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline","volume":"24","author":"Jeng","year":"2003","journal-title":"Carcinogenesis"},{"issue":"10","key":"10.1016\/j.archoralbio.2011.03.009_bib0035","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/j.1600-0714.1995.tb01132.x","article-title":"Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan","volume":"24","author":"Ko","year":"1995","journal-title":"J Oral Pathol Med"},{"issue":"7","key":"10.1016\/j.archoralbio.2011.03.009_bib0040","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1093\/carcin\/21.7.1365","article-title":"Areca nut extract up-regulates prostaglandin production, cyclooxygenase-2 mRNA and protein expression of human oral keratinocytes","volume":"21","author":"Jeng","year":"2000","journal-title":"Carcinogenesis"},{"issue":"8","key":"10.1016\/j.archoralbio.2011.03.009_bib0045","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.oraloncology.2005.01.007","article-title":"Cell-mediated immunity and head and neck cancer: with special emphasis on betel quid chewing habit","volume":"41","author":"Chang","year":"2005","journal-title":"Oral Oncol"},{"key":"10.1016\/j.archoralbio.2011.03.009_bib0050","series-title":"Cytokines and disease","article-title":"Cytokine reference: a compendium of cytokine and other mediators of host defense","author":"Oppenheim","year":"2001"},{"key":"10.1016\/j.archoralbio.2011.03.009_bib0055","first-page":"131","article-title":"TNF and cancer: good or bad?","author":"Waterston","year":"2004","journal-title":"Cancer Ther"},{"issue":"8","key":"10.1016\/j.archoralbio.2011.03.009_bib0060","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1097\/MLG.0b013e318174e09b","article-title":"TNF-alpha drives matrix metalloproteinase-9 in squamous oral carcinogenesis","volume":"118","author":"Hohberger","year":"2008","journal-title":"Laryngoscope"},{"issue":"2","key":"10.1016\/j.archoralbio.2011.03.009_bib0065","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.archoralbio.2009.12.003","article-title":"Fibronectin supports TNF-\u03b1-induced osteopontin expression through \u03b21 integrin and ERK in HN-22 cells","volume":"55","author":"Kaomongkolgit","year":"2010","journal-title":"Arch Oral Biol"},{"issue":"6","key":"10.1016\/j.archoralbio.2011.03.009_bib0070","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1046\/j.1523-1747.2000.00001.x","article-title":"Different transcriptional activity and in vitro TNF-alpha production in psoriasis patients carrying the TNF-alpha 238A promoter polymorphism","volume":"114","author":"Kaluza","year":"2000","journal-title":"J Invest Dermatol"},{"issue":"7","key":"10.1016\/j.archoralbio.2011.03.009_bib0075","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.1073\/pnas.94.7.3195","article-title":"Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation","volume":"94","author":"Wilson","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6","key":"10.1016\/j.archoralbio.2011.03.009_bib0080","doi-asserted-by":"crossref","first-page":"R1227","DOI":"10.1186\/ar1816","article-title":"Polymorphism in the tumour necrosis factor receptor II gene is associated with circulating levels of soluble tumour necrosis factor receptors in rheumatoid arthritis","volume":"7","author":"Glossop","year":"2005","journal-title":"Arthritis Res Ther"},{"issue":"5","key":"10.1016\/j.archoralbio.2011.03.009_bib0085","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0161-5890(97)00052-7","article-title":"The \u2212308 tumor necrosis factor-alpha promoter polymorphism effects transcription","volume":"34","author":"Kroeger","year":"1997","journal-title":"Mol Immunol"},{"issue":"6","key":"10.1016\/j.archoralbio.2011.03.009_bib0090","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1093\/nar\/22.6.1108","article-title":"Identification and characterization of a novel repressor site in the human tumor necrosis factor alpha gene","volume":"22","author":"Fong","year":"1994","journal-title":"Nucleic Acids Res"},{"issue":"12","key":"10.1016\/j.archoralbio.2011.03.009_bib0095","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1177\/00220345010800120601","article-title":"Association between genetic polymorphism of tumor necrosis factor-alpha and risk of oral submucous fibrosis, a pre-cancerous condition of oral cancer","volume":"80","author":"Chiu","year":"2001","journal-title":"J Dent Res"},{"issue":"1","key":"10.1016\/j.archoralbio.2011.03.009_bib0100","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1080\/00016480410016919","article-title":"CYP17 and tumor necrosis factor-alpha gene polymorphisms are associated with risk of oral cancer in Chinese patients in Taiwan","volume":"125","author":"Chen","year":"2005","journal-title":"Acta Otolaryngol"},{"issue":"10","key":"10.1016\/j.archoralbio.2011.03.009_bib0105","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1111\/j.1600-0714.2005.00359.x","article-title":"Tumor necrosis factor-alpha promoter polymorphism is associated with susceptibility to oral squamous cell carcinoma","volume":"34","author":"Liu","year":"2005","journal-title":"J Oral Pathol Med"},{"issue":"5","key":"10.1016\/j.archoralbio.2011.03.009_bib0110","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.oraloncology.2007.06.003","article-title":"Association of TNF-alpha and TNFR1 promoters and 3\u2019 UTR region of TNFR2 gene polymorphisms with genetic susceptibility to tobacco-related oral carcinoma in Asian Indians","volume":"44","author":"Gupta","year":"2008","journal-title":"Oral Oncol"},{"issue":"6","key":"10.1016\/j.archoralbio.2011.03.009_bib0115","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/j.1600-0528.2009.00504.x","article-title":"Quantification of betel quid chewing and cigarette smoking in oral cancer patients","volume":"37","author":"Tsai","year":"2009","journal-title":"Community Dent Oral Epidemiol"},{"issue":"2","key":"10.1016\/j.archoralbio.2011.03.009_bib0120","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.oraloncology.2007.01.019","article-title":"The upregulation of metallothionein-1 expression in areca quid chewing-associated oral squamous cell carcinomas","volume":"44","author":"Lee","year":"2008","journal-title":"Oral Oncol"},{"issue":"1","key":"10.1016\/j.archoralbio.2011.03.009_bib0195","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J Royal Statistical Society"},{"issue":"2","key":"10.1016\/j.archoralbio.2011.03.009_bib0125","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0165-5728(96)00182-8","article-title":"TNF-alpha promoter polymorphisms, production and susceptibility to multiple sclerosis in different groups of patients","volume":"72","author":"Huizinga","year":"1997","journal-title":"J Neuroimmunol"},{"issue":"4","key":"10.1016\/j.archoralbio.2011.03.009_bib0130","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1634\/theoncologist.11-4-397","article-title":"TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility","volume":"11","author":"van Horssen","year":"2006","journal-title":"Oncologist"},{"issue":"4","key":"10.1016\/j.archoralbio.2011.03.009_bib0135","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1172\/JCI0216493","article-title":"Clinical use of TNF revisited: improving penetration of anti-cancer agents by increasing vascular permeability","volume":"110","author":"Lejeune","year":"2002","journal-title":"J Clin Invest"},{"issue":"8","key":"10.1016\/j.archoralbio.2011.03.009_bib0140","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1182\/blood-2006-06-026385","article-title":"Essential role of the TNF-TNFR2 cognate interaction in mouse dendritic cell-natural killer cell crosstalk","volume":"109","author":"Xu","year":"2007","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.archoralbio.2011.03.009_bib0145","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s00432-008-0494-z","article-title":"Association of leptin \u22122548G\/A and leptin receptor Q223R polymorphisms with increased risk for oral cancer","volume":"135","author":"Yapijakis","year":"2009","journal-title":"J Cancer Res Clin Oncol"},{"issue":"2","key":"10.1016\/j.archoralbio.2011.03.009_bib0150","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1158\/1055-9965.EPI-08-0347","article-title":"Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium","volume":"18","author":"Hashibe","year":"2009","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"1","key":"10.1016\/j.archoralbio.2011.03.009_bib0155","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.archoralbio.2010.08.012","article-title":"Cytogenetic alterations in buccal mucosa cells of chewers of areca nut and tobacco","volume":"56","author":"Joshi","year":"2011","journal-title":"Arch Oral Biol"},{"issue":"4","key":"10.1016\/j.archoralbio.2011.03.009_bib0160","first-page":"175","article-title":"The effects of arecoline on the release of cytokines using cultured peripheral blood mononuclear cells from patients with oral mucous diseases","volume":"17","author":"Hsu","year":"2001","journal-title":"Kaohsiung J Med Sci"},{"issue":"1","key":"10.1016\/j.archoralbio.2011.03.009_bib0165","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.atherosclerosis.2004.03.006","article-title":"Different effects of red wine and gin consumption on inflammatory biomarkers of atherosclerosis: a prospective randomized crossover trial. Effects of wine on inflammatory markers","volume":"175","author":"Estruch","year":"2004","journal-title":"Atherosclerosis"},{"issue":"5","key":"10.1016\/j.archoralbio.2011.03.009_bib0170","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1161\/01.CIR.0000109503.13955.00","article-title":"Relationship of alcohol intake with inflammatory markers and plasminogen activator inhibitor-1 in well-functioning older adults: the health, aging, and body composition study","volume":"109","author":"Volpato","year":"2004","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.archoralbio.2011.03.009_bib0175","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.jaci.2005.05.046","article-title":"Acrolein in cigarette smoke inhibits T-cell responses","volume":"116","author":"Lambert","year":"2005","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.archoralbio.2011.03.009_bib0180","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/sj.ejhg.5201294","article-title":"Biological variations, genetic polymorphisms and familial resemblance of TNF-alpha and IL-6 concentrations: STANISLAS cohort","volume":"13","author":"Haddy","year":"2005","journal-title":"Eur J Hum Genet"},{"issue":"3","key":"10.1016\/j.archoralbio.2011.03.009_bib0185","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1189\/jlb.0707481","article-title":"Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke","volume":"83","author":"Mian","year":"2008","journal-title":"J Leukoc Biol"},{"issue":"8","key":"10.1016\/j.archoralbio.2011.03.009_bib0190","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.oraloncology.2004.02.001","article-title":"Expression of tumor necrosis factor-alpha and its soluble receptors in betel-quid-chewing patients at different stages of treatment for oral squamous cell carcinoma","volume":"40","author":"Su","year":"2004","journal-title":"Oral Oncol"}],"container-title":["Archives of Oral Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996911000896?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996911000896?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T04:38:09Z","timestamp":1741149489000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003996911000896"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":39,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S0003996911000896"],"URL":"https:\/\/doi.org\/10.1016\/j.archoralbio.2011.03.009","relation":{},"ISSN":["0003-9969"],"issn-type":[{"value":"0003-9969","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]}}}