{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T11:34:33Z","timestamp":1778067273160,"version":"3.51.4"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["aobjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Oral Biology"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.archoralbio.2016.02.013","type":"journal-article","created":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T09:01:24Z","timestamp":1456390884000},"page":"92-97","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["miR-22 regulates cell invasion, migration and proliferation in vitro through inhibiting CD147 expression in tongue squamous cell carcinoma"],"prefix":"10.1016","volume":"66","author":[{"given":"Kaifeng","family":"Qiu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zixian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiquan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhichao","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siping","family":"You","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.archoralbio.2016.02.013_bib0005","doi-asserted-by":"crossref","first-page":"734","DOI":"10.5935\/1808-8694.20130134","article-title":"Prognostic value of regional metastasis in squamous cell carcinoma of the tongue and floor of mouth","volume":"79","author":"Amar","year":"2013","journal-title":"Brazilian Journal of Otorhinolaryngology"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.02.013_bib0010","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1002\/ijc.25014","article-title":"miRNA control of tumor cell invasion and metastasis","volume":"126","author":"Baranwal","year":"2010","journal-title":"International Journal of Cancer Journal International du Cancer"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.02.013_bib0015","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","article-title":"MicroRNAs: target recognition and regulatory functions","volume":"136","author":"Bartel","year":"2009","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.02.013_bib0020","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/ng.2007.30","article-title":"Widespread microRNA repression by Myc contributes to tumorigenesis","volume":"40","author":"Chang","year":"2008","journal-title":"Nature Genetics"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.02.013_bib0025","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nrc1840","article-title":"Oncomirs \u2212 microRNAs with a role in cancer","volume":"6","author":"Esquela-Kerscher","year":"2006","journal-title":"Nature Reviews Cancer"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.02.013_bib0030","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.yexcr.2010.11.004","article-title":"Let-7b-mediated suppression of basigin expression and metastasis in mouse melanoma cells","volume":"317","author":"Fu","year":"2011","journal-title":"Experimental Cell Research"},{"key":"10.1016\/j.archoralbio.2016.02.013_bib0035","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1146\/annurev-pharmtox-010510-100517","article-title":"MicroRNAs: master regulators as potential therapeutics in cancer","volume":"51","author":"Garofalo","year":"2011","journal-title":"Annual Review of Pharmacology and Toxicology"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.02.013_bib0040","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/s12032-013-0542-7","article-title":"miR-22 is down-regulated in gastric cancer, and its overexpression inhibits cell migration and invasion via targeting transcription factor Sp1","volume":"30","author":"Guo","year":"2013","journal-title":"Medical Oncology"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.02.013_bib0045","doi-asserted-by":"crossref","first-page":"7025","DOI":"10.1007\/s13277-014-1965-2","article-title":"miR-22 inhibits osteosarcoma cell proliferation and migration by targeting HMGB1 and inhibiting HMGB1-mediated autophagy","volume":"35","author":"Guo","year":"2014","journal-title":"Tumour Biology"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.02.013_bib0050","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1111\/j.1600-0714.2009.00775.x","article-title":"EMMPRIN expression in tongue squamous cell carcinoma","volume":"38","author":"Huang","year":"2009","journal-title":"Journal of Oral Pathology and Medicine"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.02.013_bib0055","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/jop.12046","article-title":"Overexpression of CD147 contributes to the chemoresistance of head and neck squamous cell carcinoma cells","volume":"42","author":"Huang","year":"2013","journal-title":"Journal of Oral Pathology and Medicine"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.02.013_bib0060","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/jop.12046","article-title":"Overexpression of CD147 contributes to the chemoresistance of head and neck squamous cell carcinoma cells","volume":"42","author":"Huang","year":"2013","journal-title":"Journal of Oral Pathology and Medicine"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.02.013_bib0065","doi-asserted-by":"crossref","first-page":"e91596","DOI":"10.1371\/journal.pone.0091596","article-title":"Overexpression of EMMPRIN isoform 2 is associated with head and neck cancer metastasis","volume":"9","author":"Huang","year":"2014","journal-title":"PLoS One"},{"issue":"368","key":"10.1016\/j.archoralbio.2016.02.013_bib0070","doi-asserted-by":"crossref","first-page":"a29","DOI":"10.1126\/scisignal.2005866","article-title":"EGF induces microRNAs that target suppressors of cell migration: miR-15b targets MTSS1 in breast cancer","volume":"8","author":"Kedmi","year":"2015","journal-title":"Science Signaling"},{"key":"10.1016\/j.archoralbio.2016.02.013_bib0075","first-page":"2015","article-title":"MicroRNA-31 functions as a tumor suppressor by regulating cell cycle and epithelial-mesenchymal transition regulatory proteins in liver cancer","author":"Kim","year":"2016","journal-title":"Oncotarget"},{"issue":"14","key":"10.1016\/j.archoralbio.2016.02.013_bib0080","doi-asserted-by":"crossref","first-page":"3764","DOI":"10.1158\/0008-5472.CAN-13-3555","article-title":"A regulatory loop involving miR-22, Sp1, and c-Myc modulates CD147 expression in breast cancer invasion and metastasis","volume":"74","author":"Kong","year":"2014","journal-title":"Cancer Research"},{"key":"10.1016\/j.archoralbio.2016.02.013_bib0085","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.2741\/4068","article-title":"MicroRNAs: molecular features and role in cancer","volume":"17","author":"Lages","year":"2012","journal-title":"Frontiers in Bioscience (Landmark Ed)"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.02.013_bib0090","first-page":"560","article-title":"MicroRNAs: small but potent oncogenes or tumor suppressors","volume":"7","author":"Lee","year":"2006","journal-title":"Current Opinion in Investigational Drugs"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.02.013_bib0095","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1111\/j.1365-2559.2009.03280.x","article-title":"HAb18G (CD147), a cancer-associated biomarker and its role in cancer detection","volume":"54","author":"Li","year":"2009","journal-title":"Histopathology"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.02.013_bib0100","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.ygyno.2010.08.034","article-title":"An inhibitory effect of miR-22 on cell migration and invasion in ovarian cancer","volume":"119","author":"Li","year":"2010","journal-title":"Gynecologic Oncology"},{"issue":"1\u20132","key":"10.1016\/j.archoralbio.2016.02.013_bib0105","first-page":"31","article-title":"Overexpression of miR-22 reverses paclitaxel-induced chemoresistance through activation of PTEN signaling in p53-mutated colon cancer cells","volume":"357","author":"Li","year":"2011","journal-title":"Molecular and Cellular Biochemistry"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.02.013_bib0110","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.3892\/or.2013.2300","article-title":"miRNA-22 suppresses colon cancer cell migration and invasion by inhibiting the expression of T-cell lymphoma invasion and metastasis 1 and matrix metalloproteinases 2 and 9","volume":"29","author":"Li","year":"2013","journal-title":"Oncology Reports"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.02.013_bib0115","doi-asserted-by":"crossref","first-page":"651","DOI":"10.3892\/or.2014.3612","article-title":"Downregulation of MACC1 inhibits invasion, migration and proliferation, attenuates cisplatin resistance and induces apoptosis in tongue squamous cell carcinoma","volume":"33","author":"Li","year":"2015","journal-title":"Oncology Reports"},{"issue":"13","key":"10.1016\/j.archoralbio.2016.02.013_bib0120","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1128\/MCB.05160-11","article-title":"Characterization of basigin isoforms and the inhibitory function of basigin-3 in human hepatocellular carcinoma proliferation and invasion","volume":"31","author":"Liao","year":"2011","journal-title":"Molecular and Cellular Biology"},{"issue":"8","key":"10.1016\/j.archoralbio.2016.02.013_bib0125","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1007\/s00432-012-1194-2","article-title":"Tumor suppressor miR-22 suppresses lung cancer cell progression through post-transcriptional regulation of ErbB3","volume":"138","author":"Ling","year":"2012","journal-title":"Journal of Cancer Research and Clinical Oncology"},{"issue":"7163","key":"10.1016\/j.archoralbio.2016.02.013_bib0130","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/nature06174","article-title":"Tumour invasion and metastasis initiated by microRNA-10b in breast cancer","volume":"449","author":"Ma","year":"2007","journal-title":"Nature"},{"issue":"38","key":"10.1016\/j.archoralbio.2016.02.013_bib0135","doi-asserted-by":"crossref","first-page":"13658","DOI":"10.3748\/wjg.v20.i38.13658","article-title":"MicroRNAs: promising chemoresistance biomarkers in gastric cancer with diagnostic and therapeutic potential","volume":"20","author":"Matuszcak","year":"2014","journal-title":"World Journal of Gastroenterology"},{"issue":"13","key":"10.1016\/j.archoralbio.2016.02.013_bib0140","doi-asserted-by":"crossref","first-page":"3783","DOI":"10.1128\/MCB.01875-08","article-title":"miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA","volume":"29","author":"Pandey","year":"2009","journal-title":"Molecular and Cellular Biology"},{"issue":"11","key":"10.1016\/j.archoralbio.2016.02.013_bib0145","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1038\/onc.2010.510","article-title":"Control of EVI-1 oncogene expression in metastatic breast cancer cells through microRNA miR-22","volume":"30","author":"Patel","year":"2011","journal-title":"Oncogene"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.02.013_bib0150","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/jop.12133","article-title":"Perineural invasion and expression of nerve growth factor can predict the progression and prognosis of oral tongue squamous cell carcinoma","volume":"43","author":"Shen","year":"2014","journal-title":"Journal of Oral Pathology and Medicine"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.02.013_bib0155","first-page":"83","article-title":"MicroRNAs: processing, maturation, target recognition and regulatory functions","volume":"3","author":"Shukla","year":"2011","journal-title":"Molecular and Cellular Pharmacology"},{"issue":"11","key":"10.1016\/j.archoralbio.2016.02.013_bib0160","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1080\/19424396.2013.12222372","article-title":"Expression of EMMPRIN modulates mediators of tumor invasion in oral squamous cell carcinoma","volume":"41","author":"Siu","year":"2013","journal-title":"Journal of the California Dental Association"},{"issue":"8","key":"10.1016\/j.archoralbio.2016.02.013_bib0165","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1261\/rna.1534709","article-title":"Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell","volume":"15","author":"Sotiropoulou","year":"2009","journal-title":"RNA"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.02.013_bib0170","doi-asserted-by":"crossref","first-page":"454","DOI":"10.3892\/mmr.2014.2682","article-title":"microRNA-22 acts as a metastasis suppressor by targeting metadherin in gastric cancer","volume":"11","author":"Tang","year":"2015","journal-title":"Molecular Medicine Reports"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.02.013_bib0175","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.bbrc.2010.03.030","article-title":"Differentiation-associated miR-22 represses Max expression and inhibits cell cycle progression","volume":"394","author":"Ting","year":"2010","journal-title":"Biochemical and Biophysical Research Communications"},{"issue":"13","key":"10.1016\/j.archoralbio.2016.02.013_bib0180","doi-asserted-by":"crossref","first-page":"4628","DOI":"10.1158\/0008-5472.CAN-10-2475","article-title":"Tumor suppressor miR-22 determines p53-dependent cellular fate through post-transcriptional regulation of p21","volume":"71","author":"Tsuchiya","year":"2011","journal-title":"Cancer Research"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.02.013_bib0185","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3233\/CBM-2012-00284","article-title":"MicroRNAs as promising biomarkers for gastric cancer","volume":"11","author":"Wang","year":"2012","journal-title":"Cancer Biomarkers"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.02.013_bib0190","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.bbrc.2014.01.160","article-title":"miR-22 suppresses the proliferation and invasion of gastric cancer cells by inhibiting CD151","volume":"445","author":"Wang","year":"2014","journal-title":"Biochemical and Biophysical Research Communications"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.02.013_bib0195","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s00439-011-1026-5","article-title":"A miRNA-492 binding-site polymorphism in BSG (basigin) confers risk to psoriasis in central south Chinese population","volume":"130","author":"Wu","year":"2011","journal-title":"Human Genetics"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.02.013_bib0200","doi-asserted-by":"crossref","first-page":"e5311","DOI":"10.1371\/journal.pone.0005311","article-title":"Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries","volume":"4","author":"Wyman","year":"2009","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.02.013_bib0205","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1111\/j.1742-4658.2010.07594.x","article-title":"An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples","volume":"277","author":"Xiong","year":"2010","journal-title":"FEBS Journal"},{"issue":"35","key":"10.1016\/j.archoralbio.2016.02.013_bib0210","doi-asserted-by":"crossref","first-page":"4980","DOI":"10.1038\/onc.2010.241","article-title":"Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein","volume":"29","author":"Xiong","year":"2010","journal-title":"Oncogene"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.02.013_bib0215","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1111\/j.1742-4658.2010.07594.x","article-title":"An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples","volume":"277","author":"Xiong","year":"2010","journal-title":"FEBS Journal"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.02.013_bib0220","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1083\/jcb.201010100","article-title":"miR-22 represses cancer progression by inducing cellular senescence","volume":"193","author":"Xu","year":"2011","journal-title":"Journal of Cell Biology"},{"issue":"Suppl. 7","key":"10.1016\/j.archoralbio.2016.02.013_bib0225","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1186\/1471-2105-15-S7-S4","article-title":"Identifying microRNA targets in different gene regions","volume":"15","author":"Xu","year":"2014","journal-title":"BMC Bioinformatics"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.02.013_bib0230","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/s12935-014-0138-0","article-title":"miR-22 is down-regulated in esophageal squamous cell carcinoma and inhibits cell migration and invasion","volume":"14","author":"Yang","year":"2014","journal-title":"Cancer Cell International"},{"issue":"2 Pt B","key":"10.1016\/j.archoralbio.2016.02.013_bib0235","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/j.canlet.2014.11.013","article-title":"GNAI3 inhibits tumor cell migration and invasion and is post-transcriptionally regulated by miR-222 in hepatocellular carcinoma","volume":"356","author":"Zhang","year":"2015","journal-title":"Cancer Letters"}],"container-title":["Archives of Oral Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996916300401?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996916300401?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T16:02:11Z","timestamp":1718380931000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003996916300401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":47,"alternative-id":["S0003996916300401"],"URL":"https:\/\/doi.org\/10.1016\/j.archoralbio.2016.02.013","relation":{},"ISSN":["0003-9969"],"issn-type":[{"value":"0003-9969","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"miR-22 regulates cell invasion, migration and proliferation in vitro through inhibiting CD147 expression in tongue squamous cell carcinoma","name":"articletitle","label":"Article Title"},{"value":"Archives of Oral Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.archoralbio.2016.02.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}