{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:46:18Z","timestamp":1791218778441,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["aobjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Oral Biology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.archoralbio.2016.07.007","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T18:37:20Z","timestamp":1469644640000},"page":"122-128","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Histologic characterization of regenerated tissues after pulp revascularization of immature dog teeth with apical periodontitis using tri-antibiotic paste and platelet-rich plasma"],"prefix":"10.1016","volume":"71","author":[{"given":"Carlos","family":"Stambolsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soledad","family":"Rodr\u00edguez-Ben\u00edtez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"Guti\u00e9rrez-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Torres-Lagares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenifer","family":"Mart\u00edn-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0427-9059","authenticated-orcid":false,"given":"Juan Jos\u00e9","family":"Segura-Egea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.archoralbio.2016.07.007_bib0005","doi-asserted-by":"crossref","first-page":"68","DOI":"10.4103\/0972-0707.92610","article-title":"Conventional apexification and revascularization induced maturogenesis of two non-vital, immature teeth in same patient: 24 months follow up of a case","volume":"15","author":"Aggarwal","year":"2012","journal-title":"Journal of Conservative Dentistry"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0010","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.joen.2014.02.016","article-title":"Radiographic and clinical outcomes of the treatment of immature permanent teeth by revascularization or apexification: A pilot retrospective cohort study","volume":"40","author":"Alobaid","year":"2014","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0015","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1034\/j.1600-9657.2002.00097.x","article-title":"Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture","volume":"18","author":"Andreasen","year":"2002","journal-title":"Dental Traumatology"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0020","first-page":"529","article-title":"Plasma rich in growth factors: Preliminary results of use in the preparation of future sites for implants","volume":"14","author":"Anitua","year":"1999","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0025","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1097\/00004770-200404000-00003","article-title":"Revascularization of inmature permanent teeth with apical periodontitis: New treatment protocol","volume":"30","author":"Banchs","year":"2004","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0030","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.joen.2006.07.010","article-title":"Immature teeth with perirradicular periodontitis or abscess undergoing apexogenesis: A paradigm shift","volume":"32","author":"Chueh","year":"2006","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0035","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S0099-2399(79)80077-1","article-title":"A comparative study of tooth apexification in the dog","volume":"5","author":"Citome","year":"1979","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0040","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.tripleo.2009.08.029","article-title":"Apical negative pressure irrigation versus conventional irrigation plus triantibiotic intracanal dressing on root canal disinfection in dog teeth","volume":"109","author":"Cohenca","year":"2010","journal-title":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0045","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/j.1600-9657.1990.tb00413.x","article-title":"Effect of topical application of doxycycline on pulp revascularization and periodontal healing in reimplanted monkey incisors","volume":"6","author":"Cvek","year":"1990","journal-title":"Endodontics and Dental Traumatology"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0050","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1016\/j.joen.2011.08.027","article-title":"Dentin conditionating codetermines cell fate in regenerative endodontics","volume":"37","author":"Galler","year":"2011","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0055","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.joen.2011.09.020","article-title":"Tissue reaction to a triantibiotic paste used for endodontic tissue self-regeneration of nonvital immature permanent teeth","volume":"38","author":"Gomes-Filho","year":"2012","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0060","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.joen.2008.02.032","article-title":"Regeneration potential of the young permanent tooth: What does the future hold","volume":"34","author":"Hargreaves","year":"2008","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0065","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/j.joen.2008.07.022","article-title":"Antimicrobial efficacy of two irrigation techniques in tapered and nontapered canal preparations: An in vitro study","volume":"34","author":"Hockett","year":"2008","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0070","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1365-2591.1996.tb01173.x","article-title":"In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline","volume":"29","author":"Hoshino","year":"1996","journal-title":"International Endodontic Journal"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0075","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1034\/j.1600-9657.2001.017004185.x","article-title":"Revascularization of an immature permanent tooth with apical periodontitis and sinus tract","volume":"17","author":"Iwaya","year":"2001","journal-title":"Dental Traumatology"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0080","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1016\/j.joen.2012.09.010","article-title":"Revascularization with and without platelet-rich plasma in nonvital, immature, anterior teeth: A pilot clinical study","volume":"38","author":"Jadhav","year":"2012","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0085","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.joen.2012.06.028","article-title":"Mahidol study 1: comparison of radiographic and survival outcomes of immature teeth treated with either regenerative endodontic or apexification methods: A retrospective study","volume":"38","author":"Jeeruphan","year":"2012","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0090","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.joen.2013.10.032","article-title":"Revascularization outcomes: A prospective analysis of 16 consecutive cases","volume":"40","author":"Kahler","year":"2014","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0095","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/edt.12100","article-title":"Outcomes of revascularization treatment in immature dog\u2019s teeth","volume":"30","author":"Khademi","year":"2014","journal-title":"Dental Traumatology"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0100","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1600-9657.1991.tb00194.x","article-title":"A study of endodontically apexified teeth","volume":"7","author":"Kleier","year":"1991","journal-title":"Endodontics and Dental Traumatology"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0105","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S0099-2399(06)81361-0","article-title":"Histological evaluation of therapy using a calcium hydroxide dressing for teeth with incompletely formed apices and periapical lesions","volume":"19","author":"Leonardo","year":"1993","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0110","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.joms.2003.12.003","article-title":"Platelet-rich plasma: Evidence to support its use","volume":"62","author":"Marx","year":"2004","journal-title":"Journal of Oral and Maxillofacial Surgery"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0115","first-page":"66","article-title":"Emerging therapies for the management of traumatized immature permanent incisors","volume":"34","author":"Miller","year":"2012","journal-title":"Pediatric Dentistry"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0120","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.joen.2006.09.013","article-title":"Regenerative endodontics: A review of current status and a call for action","volume":"33","author":"Murray","year":"2007","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0125","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.joen.2013.10.027","article-title":"Regenerative potential of immature permanent teeth with necrotic pulps after different regenerative protocols","volume":"40","author":"Nagy","year":"2014","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0130","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/S0099-2399(98)80121-0","article-title":"A clinical study using the collagen gel Zyplast in endodontic treatment","volume":"24","author":"Nevins","year":"1998","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0135","doi-asserted-by":"crossref","first-page":"324","DOI":"10.3109\/00016356109043395","article-title":"The role of the blood clot in endodontic therapy: An experimental histologic study","volume":"19","author":"Ostby","year":"1961","journal-title":"Acta Odontologica Scandinavica"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0140","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.joen.2009.10.006","article-title":"Challenges in regenerative endodontics: A case series","volume":"36","author":"Petrino","year":"2010","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-9657.2004.00284.x","article-title":"Apexification: A review","volume":"21","author":"Rafter","year":"2005","journal-title":"Dental Traumatology"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0150","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.joen.2015.05.002","article-title":"Pulp revascularization of immature dog teeth with apical periodontitis using tri-antibiotic paste and platelet-rich plasma: Radiographic study","volume":"41","author":"Rodr\u00edguez-Benitez","year":"2015","journal-title":"J Endodon"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0155","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.joen.2007.03.001","article-title":"Pulp revascularization of immature dog teeth with apical periodontitis","volume":"33","author":"Thibodeau","year":"2007","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0160","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0099-2399(99)80142-3","article-title":"Clinical applications of mineral trioxide aggregate","volume":"25","author":"Torabinejad","year":"1999","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0165","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.joen.2012.03.006","article-title":"A clinical and histological report of a tooth with an open apex treated with regenerative endodontics using platelet-rich plasma","volume":"38","author":"Torabinejad","year":"2012","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0170","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.joen.2010.11.004","article-title":"Revitalization of tooth with necrotic pulp and open apex by using platelet-rich plasma: A case report","volume":"37","author":"Torabinejad","year":"2011","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0175","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.joen.2013.12.025","article-title":"Histologic examinations of teeth treated with 2 scaffolds: A pilot animal investigation","volume":"40","author":"Torabinejad","year":"2014","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0180","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.joen.2015.01.026","article-title":"Histologic examination of teeth with necrotic pulps and periapical lesions treated with 2 scaffolds: An animal investigation","volume":"41","author":"Torabinejad","year":"2015","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0185","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.joen.2011.05.013","article-title":"Effect of irrigants on the survival of human stem cells of the apical papilla in a platelet-rich plasma scaffold in human root tips","volume":"37","author":"Trevino","year":"2011","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0190","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.joen.2009.09.039","article-title":"Histologic characterization of regenerated tissues in canal space after the revitalization\/revascularization procedure of immature dog teeth with apical periodontitis","volume":"36","author":"Wang","year":"2010","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0195","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.joen.2012.11.014","article-title":"Revascularization: A treatment for permanent teeth with necrotic pulp and incomplete root development","volume":"39","author":"Wigler","year":"2013","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0200","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1097\/01.don.0000148143.80283.ea","article-title":"Disinfection of immature teeth with a triple antibiotic paste","volume":"31","author":"Windley","year":"2005","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0205","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.joen.2010.11.010","article-title":"Tissue engineering strategies for immature teeth with apical periodontitis","volume":"37","author":"Yamauchi","year":"2011","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0210","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.joen.2014.03.020","article-title":"Histologic comparison between platelet-rich plasma and blood clot in regenerative endodontic treatment: An animal study","volume":"40","author":"Zhang","year":"2014","journal-title":"Journal of Endodontics"},{"key":"10.1016\/j.archoralbio.2016.07.007_bib0215","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1016\/j.joen.2014.05.010","article-title":"Immunohistochemical and histochemical analysis of newly formed tissues in root canal space transplanted with dental pulp stem cells plus platelet-rich plasma","volume":"40","author":"Zhu","year":"2014","journal-title":"Journal of Endodontics"}],"container-title":["Archives of Oral Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996916301868?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996916301868?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,10]],"date-time":"2018-09-10T02:25:06Z","timestamp":1536546306000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003996916301868"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":43,"alternative-id":["S0003996916301868"],"URL":"https:\/\/doi.org\/10.1016\/j.archoralbio.2016.07.007","relation":{},"ISSN":["0003-9969"],"issn-type":[{"value":"0003-9969","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Histologic characterization of regenerated tissues after pulp revascularization of immature dog teeth with apical periodontitis using tri-antibiotic paste and platelet-rich plasma","name":"articletitle","label":"Article Title"},{"value":"Archives of Oral Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.archoralbio.2016.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}