{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:54:30Z","timestamp":1760889270418,"version":"3.40.5"},"reference-count":119,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["aobjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Oral Biology"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.archoralbio.2016.09.014","type":"journal-article","created":{"date-parts":[[2016,10,9]],"date-time":"2016-10-09T11:33:15Z","timestamp":1476012795000},"page":"136-145","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Relevance of the plasminogen system in physiology, pathology, and regeneration of oral tissues \u2013 From the perspective of dental specialties"],"prefix":"10.1016","volume":"74","author":[{"given":"Christian","family":"Wehner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klara","family":"Janji\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9509-1555","authenticated-orcid":false,"given":"Hermann","family":"Agis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0005","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/j.1600-0765.2007.01038.x","article-title":"Effects of platelet-derived growth factor isoforms on plasminogen activation by periodontal ligament and gingival fibroblasts","volume":"43","author":"Agis","year":"2008","journal-title":"Journal of Periodontal Research"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.09.014_bib0010","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1002\/jor.20819","article-title":"Activated platelets increase fibrinolysis of mesenchymal progenitor cells","volume":"27","author":"Agis","year":"2009","journal-title":"Journal of Orthopaedic Research"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0015","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1600-0765.2011.01415.x","article-title":"Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor by periodontal fibroblasts","volume":"47","author":"Agis","year":"2012","journal-title":"Journal of Periodontal Research"},{"key":"10.1016\/j.archoralbio.2016.09.014_bib0020","first-page":"54","article-title":"The plasminogen activator inhibitor system in bone cell function","volume":"313","author":"Allan","year":"1995","journal-title":"Clinical Orthopaedics and Related Research"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0025","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1002\/jcp.1041490106","article-title":"Transforming growth factor beta inhibits plasminogen activator (PA) activity and stimulates production of urokinase-type PA, PA inhibitor-1 mRNA, and protein in rat osteoblast-like cells","volume":"149","author":"Allan","year":"1991","journal-title":"J Cell Physiol"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0030","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s000180050497","article-title":"The plasminogen activation system in tumor growth, invasion, and metastasis","volume":"57","author":"Andreasen","year":"2000","journal-title":"Cell Mol Life Sci"},{"issue":"11","key":"10.1016\/j.archoralbio.2016.09.014_bib0035","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1084\/jem.187.11.1799","article-title":"The serine proteinase inhibitor (serpin) plasminogen activation inhibitor type 2 protects against viral cytopathic effects by constitutive interferon alpha\/beta priming","volume":"187","author":"Antalis","year":"1998","journal-title":"J Exp Med"},{"issue":"3\u20134","key":"10.1016\/j.archoralbio.2016.09.014_bib0040","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0049-3848(79)90093-8","article-title":"Occurrence of both urokinase and tissue plasminogen activator in human seminal plasma","volume":"16","author":"Astedt","year":"1979","journal-title":"Thromb Res"},{"issue":"11","key":"10.1016\/j.archoralbio.2016.09.014_bib0045","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1902\/jop.2012.120592","article-title":"The frequency of peri-implant diseases: a systematic review and meta-analysis","volume":"84","author":"Atieh","year":"2013","journal-title":"J Periodontol"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0050","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0092-8674(80)90112-9","article-title":"Protease-nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells","volume":"21","author":"Baker","year":"1980","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.archoralbio.2016.09.014_bib0055","first-page":"ZE20","article-title":"Regenerative endodontics: a road less travelled","volume":"8","author":"Bansal","year":"2014","journal-title":"J Clin Diagn Res"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.09.014_bib0060","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/35074588","article-title":"PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor","volume":"3","author":"Bergsten","year":"2001","journal-title":"Nat Cell Biol"},{"issue":"50","key":"10.1016\/j.archoralbio.2016.09.014_bib0065","doi-asserted-by":"crossref","first-page":"43164","DOI":"10.1074\/jbc.M111.245647","article-title":"Association of plasminogen activator inhibitor type 2 (PAI-2) with proteasome within endothelial cells activated with inflammatory stimuli","volume":"286","author":"Boncela","year":"2011","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0070","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/00003081-198528010-00002","article-title":"Current concepts of coagulation","volume":"28","author":"Brandt","year":"1985","journal-title":"Clin Obstet Gynecol"},{"issue":"8","key":"10.1016\/j.archoralbio.2016.09.014_bib0075","doi-asserted-by":"crossref","first-page":"e71104","DOI":"10.1371\/journal.pone.0071104","article-title":"Angiogenic properties of human dental pulp stem cells","volume":"8","author":"Bronckaers","year":"2013","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.archoralbio.2016.09.014_bib0080","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/0003-9969(95)00049-U","article-title":"Molecular characterization of plasminogen activators in human gingival crevicular fluid","volume":"40","author":"Brown","year":"1995","journal-title":"Arch Oral Biol"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.09.014_bib0085","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/j.1600-051X.2004.00517.x","article-title":"Plasminogen activators and plasminogen activator inhibitors in gingival crevicular fluid of cyclosporin A-treated patients","volume":"31","author":"Buduneli","year":"2004","journal-title":"J Clin Periodontol"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0090","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/j.1600-051X.2005.00694.x","article-title":"Plasminogen activator system in smokers and non-smokers with and without periodontal disease","volume":"32","author":"Buduneli","year":"2005","journal-title":"J Clin Periodontol"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0095","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1160\/TH04-12-0842","article-title":"Structure and function of the plasminogen\/plasmin system","volume":"93","author":"Castellino","year":"2005","journal-title":"Thromb Haemost"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0100","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1097\/00004770-200302000-00007","article-title":"Induction of tissue plasminogen activator gene expression by proinflammatory cytokines in human pulp and gingival fibroblasts","volume":"29","author":"Chang","year":"2003","journal-title":"J Endod"},{"issue":"1\u20132","key":"10.1016\/j.archoralbio.2016.09.014_bib0105","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1089\/ten.tea.2013.0006","article-title":"Cyclic tensile strain enhances osteogenesis and angiogenesis in mesenchymal stem cells from osteoporotic donors","volume":"20","author":"Charoenpanich","year":"2014","journal-title":"Tissue Eng Part A"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.09.014_bib0110","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1359\/jbmr.2003.18.7.1167","article-title":"Increased bone formation in mice lacking plasminogen activators","volume":"18","author":"Daci","year":"2003","journal-title":"J Bone Miner Res"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.09.014_bib0115","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1359\/jbmr.1999.14.6.946","article-title":"The role of the plasminogen system in bone resorption in vitro","volume":"14","author":"Daci","year":"1999","journal-title":"J Bone Miner Res"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0120","first-page":"165","article-title":"Content of urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in oral mucosa and inflamed periodontal tissue","volume":"41","author":"Deppe","year":"2010","journal-title":"Quintessence Int"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0125","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1053\/gast.2002.31885","article-title":"Tissue plasminogen activator is required for the growth, invasion, and angiogenesis of pancreatic tumor cells","volume":"122","author":"D\u00edaz","year":"2002","journal-title":"Gastroenterology"},{"issue":"12","key":"10.1016\/j.archoralbio.2016.09.014_bib0130","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1007\/s00011-006-6074-2","article-title":"Adjunctive low-dose doxycycline therapy effect on clinical parameters and gingival crevicular fluid tissue plasminogen activator levels in chronic periodontitis","volume":"55","author":"Emingil","year":"2006","journal-title":"Inflamm Res"},{"issue":"10","key":"10.1016\/j.archoralbio.2016.09.014_bib0135","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1038\/labinvest.3780354","article-title":"The urokinase plasminogen activator receptor-associated protein\/endo180 is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis","volume":"81","author":"Engelholm","year":"2001","journal-title":"Lab Invest"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.09.014_bib0140","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.bone.2008.07.004","article-title":"Plasminogen activators are involved in the degradation of bone by osteoclasts","volume":"43","author":"Everts","year":"2008","journal-title":"Bone"},{"issue":"26","key":"10.1016\/j.archoralbio.2016.09.014_bib0145","doi-asserted-by":"crossref","first-page":"16031","DOI":"10.1074\/jbc.M115.645572","article-title":"Porphyromonas gingivalis-derived RgpA-Kgp Complex Activates the Macrophage Urokinase Plasminogen Activator System: IMPLICATIONS FOR PERIODONTITIS","volume":"290","author":"Fleetwood","year":"2015","journal-title":"J Biol Chem"},{"issue":"29","key":"10.1016\/j.archoralbio.2016.09.014_bib0150","doi-asserted-by":"crossref","first-page":"26856","DOI":"10.1074\/jbc.M503388200","article-title":"Structural requirements for activation of latent platelet-derived growth factor CC by tissue plasminogen activator","volume":"280","author":"Fredriksson","year":"2005","journal-title":"J Biol Chem"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0155","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.cytogfr.2004.03.007","article-title":"The PDGF family: four gene products form five dimeric isoforms","volume":"15","author":"Fredriksson","year":"2004","journal-title":"Cytokine Growth Factor Rev"},{"issue":"19","key":"10.1016\/j.archoralbio.2016.09.014_bib0160","doi-asserted-by":"crossref","first-page":"3793","DOI":"10.1038\/sj.emboj.7600397","article-title":"Tissue plasminogen activator is a potent activator of PDGF-CC","volume":"23","author":"Fredriksson","year":"2004","journal-title":"EMBO J"},{"issue":"9","key":"10.1016\/j.archoralbio.2016.09.014_bib0165","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1359\/jbmr.070516","article-title":"Urokinase plasminogen activator receptor affects bone homeostasis by regulating osteoblast and osteoclast function","volume":"22","author":"Furlan","year":"2007","journal-title":"J Bone Miner Res"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0170","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1182\/blood.V74.2.722.722","article-title":"Complex formation between urokinase and plasma protein C inhibitor in vitro and in vivo","volume":"74","author":"Geiger","year":"1989","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0175","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1574-695X.2011.00789.x","article-title":"Prevotella intermedia stimulates tissue-type plasminogen activator and plasminogen activator inhibitor-2 expression via multiple signaling pathways in human periodontal ligament cells","volume":"62","author":"Guan","year":"2011","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0180","first-page":"153","article-title":"A controlled, cross-sectional exploratory study on markers for the plasminogen system and inflammation in crevicular fluid samples from healthy, mucositis and peri-implantitis sites","volume":"8","author":"Hall","year":"2015","journal-title":"Eur J Oral Implantol"},{"issue":"33","key":"10.1016\/j.archoralbio.2016.09.014_bib0185","doi-asserted-by":"crossref","first-page":"15813","DOI":"10.1016\/S0021-9258(18)47659-4","article-title":"Immunological identity of heparin-dependent plasma and urinary protein C inhibitor and plasminogen activator inhibitor-3","volume":"262","author":"Heeb","year":"1987","journal-title":"J Biol Chem"},{"issue":"24","key":"10.1016\/j.archoralbio.2016.09.014_bib0190","doi-asserted-by":"crossref","first-page":"4759","DOI":"10.1007\/s00018-015-2035-7","article-title":"Role of mesenchymal stem cell-derived fibrinolytic factor in tissue regeneration and cancer progression","volume":"72","author":"Heissig","year":"2015","journal-title":"Cell Mol Life Sci"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0195","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0268-9499(98)80381-0","article-title":"Urokinase mediates bFGF-induced vascular smooth muscle cell migration under the control of TGF beta","volume":"12","author":"Herbert","year":"1998","journal-title":"Fibrinolysis & Proteolysis"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.09.014_bib0200","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0099-2399(98)80129-5","article-title":"Stimulatory effect of interleukin-6 on plasminogen activator activity from human dental pulp cells","volume":"24","author":"Hosoya","year":"1998","journal-title":"J Endod"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0205","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.joen.2007.12.021","article-title":"Up-regulation of gelatinases and tissue type plasminogen activator by root canal sealers in human osteoblastic cells","volume":"34","author":"Huang","year":"2008","journal-title":"J Endod"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0210","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.ijom.2013.10.010","article-title":"Effects of transforming growth factor beta 1 on the plasminogen activation system, collagen and integrin synthesis, and proliferation of rabbit mandibular condylar chondrocytes","volume":"43","author":"Ishibashi","year":"2014","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0215","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1365-2141.2012.09074.x","article-title":"PAI-1, progress in understanding the clinical problem and its aetiology","volume":"157","author":"Iwaki","year":"2012","journal-title":"Br J Haematol"},{"issue":"23\u201324","key":"10.1016\/j.archoralbio.2016.09.014_bib0220","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1089\/ten.tea.2014.0399","article-title":"Recombinant Human Plasminogen Activator Inhibitor-1 Promotes Cementogenic Differentiation of Human Periodontal Ligament Stem Cells","volume":"21","author":"Jin","year":"2015","journal-title":"Tissue Eng Part A"},{"issue":"9","key":"10.1016\/j.archoralbio.2016.09.014_bib0225","doi-asserted-by":"crossref","first-page":"e12746","DOI":"10.1371\/journal.pone.0012746","article-title":"Neutralisation of uPA with a monoclonal antibody reduces plasmin formation and delays skin wound healing in tPA-deficient mice","volume":"5","author":"J\u00f6gi","year":"2010","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.archoralbio.2016.09.014_bib0230","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1016\/j.bcp.2008.02.018","article-title":"Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp","volume":"75","author":"Kamio","year":"2008","journal-title":"Biochem Pharmacol"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.09.014_bib0235","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/wrr.12312","article-title":"Compression-induced HIF-1 enhances thrombosis and PAI-1 expression in mouse skin","volume":"23","author":"Kaneko","year":"2015","journal-title":"Wound Repair Regen"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0240","first-page":"152","article-title":"Levels of t-PA and PAI-2 in gingival crevicular fluid during orthodontic tooth movement in adults","volume":"21","author":"Kapoor","year":"2005","journal-title":"Aust Orthod J"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.09.014_bib0245","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1002\/jbmr.1921","article-title":"Plasminogen plays a crucial role in bone repair","volume":"28","author":"Kawao","year":"2013","journal-title":"J Bone Miner Res"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0250","doi-asserted-by":"crossref","first-page":"E278","DOI":"10.1152\/ajpendo.00129.2014","article-title":"Tissue-type plasminogen activator deficiency delays bone repair: roles of osteoblastic proliferation and vascular endothelial growth factor","volume":"307","author":"Kawao","year":"2014","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0255","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1515\/BC.2002.008","article-title":"The plasminogen activating system in periodontal health and disease","volume":"383","author":"Kinnby","year":"2002","journal-title":"Biol Chem"},{"issue":"12","key":"10.1016\/j.archoralbio.2016.09.014_bib0260","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/S0003-9969(99)00098-9","article-title":"Localization of plasminogen activators and plasminogen-activator inhibitors in human gingival tissues demonstrated by immunohistochemistry and in situ hybridization","volume":"44","author":"Kinnby","year":"1999","journal-title":"Arch Oral Biol"},{"issue":"73","key":"10.1016\/j.archoralbio.2016.09.014_bib0265","first-page":"29","article-title":"Enzymological aspects of blood coagulation","author":"Kisiel","year":"1983","journal-title":"Behring Inst Mitt"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0270","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1160\/TH13-06-0517","article-title":"Human tissue-type plasminogen activator","volume":"112","author":"Kruithof","year":"2014","journal-title":"Thromb Haemost"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.09.014_bib0275","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1177\/00220345000790061201","article-title":"Interleukin-1alpha-dependent regulation of matrix metalloproteinase-9(MMP-9) secretion and activation in the epithelial cells of odontogenic jaw cysts","volume":"79","author":"Kubota","year":"2000","journal-title":"J Dent Res"},{"issue":"8","key":"10.1016\/j.archoralbio.2016.09.014_bib0280","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/icb.2015.25","article-title":"GM-CSF and uPA are required for Porphyromonas gingivalis-induced alveolar bone loss in a mouse periodontitis model","volume":"93","author":"Lam","year":"2015","journal-title":"Immunol Cell Biol"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0285","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1136\/jcp.38.2.140","article-title":"Immunohistochemical localisation of tissue plasminogen activator and urokinase in the vessel wall","volume":"38","author":"Larsson","year":"1985","journal-title":"J Clin Pathol"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.09.014_bib0290","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1038\/35010579","article-title":"PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor","volume":"2","author":"Li","year":"2000","journal-title":"Nat Cell Biol"},{"issue":"2\u20133","key":"10.1016\/j.archoralbio.2016.09.014_bib0295","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1054\/fipr.2000.0065","article-title":"Molecular interactions between the plasminogen\/plasmin and matrix metalloproteinase systems","volume":"14","author":"Lijnen","year":"2000","journal-title":"Fibrinolysis & Proteolysis"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0300","first-page":"30","article-title":"Tissue plasminogen activator and inflammation: from phenotype to signaling mechanisms","volume":"3","author":"Lin","year":"2014","journal-title":"Am J Clin Exp Immunol"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0305","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0003-9969(00)00098-4","article-title":"Increasing expression of tissue plasminogen activator and plasminogen activator inhibitor type 2 in dog gingival tissues with progressive inflammation","volume":"46","author":"Lindberg","year":"2001","journal-title":"Arch Oral Biol"},{"issue":"22","key":"10.1016\/j.archoralbio.2016.09.014_bib0310","doi-asserted-by":"crossref","first-page":"14580","DOI":"10.1016\/S0021-9258(18)98725-9","article-title":"Single chain urokinase. Augmentation of enzymatic activity upon binding to monocytes","volume":"266","author":"Manchanda","year":"1991","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0315","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/(SICI)1097-0177(199801)211:1<11::AID-AJA2>3.0.CO;2-A","article-title":"Insulin-like growth factor II receptor, transforming growth factor-beta, and Cdk4 expression and the developmental epigenetics of mouse palate morphogenesis and dysmorphogenesis","volume":"211","author":"Melnick","year":"1998","journal-title":"Dev Dyn"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0320","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1002\/jcp.21526","article-title":"Shear stress-induced Ets-1 modulates protease inhibitor expression in microvascular endothelial cells","volume":"217","author":"Milkiewicz","year":"2008","journal-title":"J Cell Physiol"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0325","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s11248-006-0006-3","article-title":"Urokinase-type plasminogen activator mRNA is expressed in normal developing teeth and leads to abnormal incisor enamel in alpha MUPA transgenic mice","volume":"15","author":"Miskin","year":"2006","journal-title":"Transgenic Res"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.09.014_bib0330","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.lfs.2006.01.040","article-title":"Effect of compressive force on the expression of MMPs, PAs, and their inhibitors in osteoblastic Saos-2 cells","volume":"79","author":"Mitsui","year":"2006","journal-title":"Life Sci"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0335","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0047-6374(99)00095-0","article-title":"Mechanical stress enhances expression and production of plasminogen activator in aging human periodontal ligament cells","volume":"112","author":"Miura","year":"2000","journal-title":"Mech Ageing Dev"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.09.014_bib0340","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.joen.2016.02.009","article-title":"Role of pH Changes on Transforming Growth Factor-\u03b21 Release and on the Fibrin Architecture of Platelet-rich Fibrin When Layered with Biodentine, Glass Ionomer Cement, and Intermediate Restorative Material","volume":"42","author":"Mullaguri","year":"2016","journal-title":"J Endod"},{"issue":"22","key":"10.1016\/j.archoralbio.2016.09.014_bib0345","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1007\/s00018-004-4230-9","article-title":"Regulation and interactions in the activation of cell-associated plasminogen","volume":"61","author":"My\u00f6h\u00e4nen","year":"2004","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.archoralbio.2016.09.014_bib0350","doi-asserted-by":"crossref","first-page":"737503","DOI":"10.1155\/2014\/737503","article-title":"Pulp revascularization of immature permanent teeth: a review of the literature and a proposal of a new clinical protocol","volume":"2014","author":"Namour","year":"2014","journal-title":"ScientificWorldJournal"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0355","doi-asserted-by":"crossref","first-page":"329","DOI":"10.2334\/josnusd.54.329","article-title":"Tumor necrosis factor \u03b1 stimulates expression and secretion of urokinase plasminogen activator in human dental pulp cells","volume":"54","author":"Narita","year":"2012","journal-title":"J Oral Sci"},{"key":"10.1016\/j.archoralbio.2016.09.014_bib0360","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.archoralbio.2016.05.016","article-title":"PAI-2\/SerpinB2 inhibits proteolytic activity in a P: gingivalis-dominated multispecies bacterial consortium","volume":"70","author":"Neilands","year":"2016","journal-title":"Arch Oral Biol"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.09.014_bib0365","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1177\/154405910508400709","article-title":"Cleavage of PDGF receptor on periodontal ligament cells by elastase","volume":"84","author":"Nemoto","year":"2005","journal-title":"J Dent Res"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0370","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1902\/jop.2012.120141","article-title":"Platelet-derived growth factor promotes periodontal regeneration in localized osseous defects: 36-month extension results from a randomized, controlled, double-masked clinical trial","volume":"84","author":"Nevins","year":"2013","journal-title":"J Periodontol"},{"issue":"21","key":"10.1016\/j.archoralbio.2016.09.014_bib0375","doi-asserted-by":"crossref","first-page":"4302","DOI":"10.1182\/blood-2009-08-236851","article-title":"Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration","volume":"115","author":"Ohki","year":"2010","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0380","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1034\/j.1600-0765.2002.00325.x","article-title":"Plasminogen activating capacity in gingival fluid from deteriorating and stable periodontal pockets","volume":"37","author":"Olofsson","year":"2002","journal-title":"J Periodontal Res"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0385","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1161\/01.ATV.0000201087.23877.e1","article-title":"Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways","volume":"26","author":"Otsuka","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.09.014_bib0390","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1002\/(SICI)1096-9101(1997)21:5<456::AID-LSM7>3.0.CO;2-P","article-title":"Low-energy diode laser irradiation reduced plasminogen activator activity in human periodontal ligament cells","volume":"21","author":"Ozawa","year":"1997","journal-title":"Lasers Surg Med"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0395","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0268-9499(99)90079-6","article-title":"Plasminogen and cell migration in vivo","volume":"13","author":"Plow","year":"1999","journal-title":"Fibrinolysis & Proteolysis"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0400","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s00774-013-0475-4","article-title":"Urokinase plasminogen activator gene deficiency inhibits fracture cartilage remodeling","volume":"32","author":"Popa","year":"2014","journal-title":"J Bone Miner Metab"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0405","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1046\/j.1524-475x.2000.00226.x","article-title":"Mechanical loading regulates protease production by fibroblasts in three-dimensional collagen substrates","volume":"8","author":"Prajapati","year":"2000","journal-title":"Wound Repair Regen"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.09.014_bib0410","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1016\/S0021-9258(19)81052-9","article-title":"Fibrinolytic properties of one-chain and two-chain human extrinsic (tissue-type) plasminogen activator","volume":"257","author":"Rijken","year":"1982","journal-title":"J Biol Chem"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0415","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.joen.2013.09.022","article-title":"Fibrin gel improves tissue ingrowth and cell differentiation in human immature premolars implanted in rats","volume":"40","author":"Ruangsawasdi","year":"2014","journal-title":"J Endod"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0420","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1007\/s00223-008-9169-7","article-title":"Fracture healing in mice deficient in plasminogen activator inhibitor-1","volume":"83","author":"Rundle","year":"2008","journal-title":"Calcif Tissue Int"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0425","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1083\/jcb.110.3.767","article-title":"Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity","volume":"110","author":"Saksela","year":"1990","journal-title":"J Cell Biol"},{"issue":"9","key":"10.1016\/j.archoralbio.2016.09.014_bib0430","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1016\/j.joen.2015.03.019","article-title":"Revascularization Technique for the Treatment of External Inflammatory Root Resorption: A Report of 3 Cases","volume":"41","author":"Santiago","year":"2015","journal-title":"J Endod"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0435","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1002\/cam4.229","article-title":"Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis","volume":"3","author":"Schroder","year":"2014","journal-title":"Cancer Med"},{"issue":"8","key":"10.1016\/j.archoralbio.2016.09.014_bib0440","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.1182\/blood.V73.8.2188.2188","article-title":"Endotoxin-induced production of plasminogen activator inhibitor by human monocytes is autonomous and can be inhibited by lipid X","volume":"73","author":"Schwartz","year":"1989","journal-title":"Blood"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.09.014_bib0445","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1111\/j.1600-0722.2006.00412.x","article-title":"Plasminogen activators and inhibitor type-1 in alveolar osteitis","volume":"114","author":"Serrat\u00ec","year":"2006","journal-title":"Eur J Oral Sci"},{"issue":"8","key":"10.1016\/j.archoralbio.2016.09.014_bib0450","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1111\/j.1601-0825.2010.01679.x","article-title":"Urokinase and its receptor in follicular and inflammatory cysts of the jaws","volume":"16","author":"Serrat\u00ec","year":"2010","journal-title":"Oral Dis"},{"key":"10.1016\/j.archoralbio.2016.09.014_bib0455","doi-asserted-by":"crossref","first-page":"53","DOI":"10.22203\/eCM.v015a05","article-title":"Bone development and its relation to fracture repair: The role of mesenchymal osteoblasts and surface osteoblasts","volume":"15","author":"Shapiro","year":"2008","journal-title":"Eur Cell Mater"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.09.014_bib0460","first-page":"717","article-title":"Presence of urokinase-type plasminogen activator receptor in urine of cancer patients and its possible clinical relevance","volume":"79","author":"Sier","year":"1999","journal-title":"Lab Invest"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0465","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.joen.2012.10.005","article-title":"Pulp revascularization after root canal decontamination with calcium hydroxide and 2% chlorhexidine gel","volume":"39","author":"Soares Ade","year":"2013","journal-title":"J Endod"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0470","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.ajpath.2011.05.003","article-title":"Plasmin is essential in preventing periodontitis in mice","volume":"179","author":"Sulniute","year":"2011","journal-title":"Am J Pathol"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.09.014_bib0475","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1160\/TH15-08-0653","article-title":"Plasminogen is a critical regulator of cutaneous wound healing","volume":"115","author":"Sulniute","year":"2016","journal-title":"Thromb Haemost"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0480","first-page":"523","article-title":"Angiostatic activity of synthetic inhibitors of urokinase type plasminogen activator","volume":"6","author":"Swiercz","year":"1999","journal-title":"Oncol Rep"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0485","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s101030050045","article-title":"Reduction of Plasminogen Activator Activity Stimulated by Lipopolysaccharide from Periodontal Pathogen in Human Gingival Fibroblasts by Low-energy Laser Irradiation","volume":"15","author":"Takema","year":"2000","journal-title":"Lasers Med Sci"},{"issue":"9","key":"10.1016\/j.archoralbio.2016.09.014_bib0490","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1182\/blood-2006-04-017350","article-title":"Molecular and clinical spectrum of type I plasminogen deficiency: A series of 50 patients","volume":"108","author":"Tefs","year":"2006","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0495","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1432-1033.1988.tb14162.x","article-title":"Kinetics of inhibition of tissue-type and urokinase-type plasminogen activator by plasminogen-activator inhibitor type 1 and type 2","volume":"175","author":"Thorsen","year":"1988","journal-title":"Eur J Biochem"},{"issue":"14","key":"10.1016\/j.archoralbio.2016.09.014_bib0500","doi-asserted-by":"crossref","first-page":"5648","DOI":"10.1158\/0008-5472.CAN-07-5850","article-title":"SerpinB2 protection of retinoblastoma protein from calpain enhances tumor cell survival","volume":"68","author":"Tonnetti","year":"2008","journal-title":"Cancer Res"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0505","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00018-008-8388-4","article-title":"Proteinases in cutaneous wound healing","volume":"66","author":"Toriseva","year":"2009","journal-title":"Cell Mol Life Sci"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0510","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/jre.12179","article-title":"Evaluation of gingival crevicular fluid levels of tissue plasminogen activator, plasminogen activator inhibitor 2, matrix metalloproteinase-3 and interleukin 1-\u03b2 in patients with different periodontal diseases","volume":"50","author":"Toyman","year":"2015","journal-title":"J Periodontal Res"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0515","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.0904-2512.2004.00133.x","article-title":"Immunohistochemical localization of tissue-type plasminogen activator and type I plasminogen activator inhibitor in radicular cysts","volume":"33","author":"Tsai","year":"2004","journal-title":"J Oral Pathol Med"},{"issue":"14","key":"10.1016\/j.archoralbio.2016.09.014_bib0520","doi-asserted-by":"crossref","first-page":"6279","DOI":"10.1128\/MCB.25.14.6279-6288.2005","article-title":"Platelet-derived growth factor D is activated by urokinase plasminogen activator in prostate carcinoma cells","volume":"25","author":"Ustach","year":"2005","journal-title":"Mol Cell Biol"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0525","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/nm0396-284","article-title":"Cuts and scrapes?","volume":"2","author":"Vassalli","year":"1996","journal-title":"Plasmin heals! Nat Med"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0530","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1055\/s-0038-1657308","article-title":"Purification of urokinase from complex mixtures using immobilized monoclonal antibody against urokinase light chain","volume":"49","author":"Vetterlein","year":"1983","journal-title":"Thromb Haemost"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.09.014_bib0535","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/s00418-013-1109-6","article-title":"Immunocytochemical and biochemical detection of the urokinase-type plasminogen activator receptor (uPAR) in the rat tooth germ and in lipid rafts of PMA-stimulated dental epithelial cells","volume":"140","author":"von Germar","year":"2013","journal-title":"Histochem Cell Biol"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0540","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/j.1432-1033.1983.tb07418.x","article-title":"Purification and characterization of a melanoma cell plasminogen activator","volume":"132","author":"Wall\u00e9n","year":"1983","journal-title":"Eur J Biochem"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0545","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1902\/jop.2013.120703","article-title":"L-mimosine and dimethyloxaloylglycine decrease plasminogen activation in periodontal fibroblasts","volume":"85","author":"Wehner","year":"2014","journal-title":"J Periodontol"},{"issue":"18","key":"10.1016\/j.archoralbio.2016.09.014_bib0550","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1056\/NEJM197705052961801","article-title":"Endogenous activiation of latent collagenase by rheumatoid synovial cells. Evidence for a role of plasminogen activator","volume":"296","author":"Werb","year":"1977","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.archoralbio.2016.09.014_bib0555","doi-asserted-by":"crossref","first-page":"3276","DOI":"10.1016\/S0021-9258(19)81106-7","article-title":"Isolation and characterization of urokinase from human plasma","volume":"257","author":"Wun","year":"1982","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0560","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3892\/ijo.2015.3021","article-title":"Plasminogen activation system in oral cancer: Relevance in prognosis and therapy (Review)","volume":"47","author":"Wyganowska-Swiatkowska","year":"2015","journal-title":"Int J Oncol"},{"issue":"4","key":"10.1016\/j.archoralbio.2016.09.014_bib0565","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3892\/ijmm.2014.1653","article-title":"The plasminogen activation system in periodontal tissue (Review)","volume":"33","author":"Wyganowska-Swiatkowska","year":"2014","journal-title":"Int J Mol Med"},{"issue":"1","key":"10.1016\/j.archoralbio.2016.09.014_bib0570","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1600-0765.1998.tb02287.x","article-title":"Immunohistochemical demonstration of the plasminogen activator system in human gingival tissues and gingival fibroblasts","volume":"33","author":"Xiao","year":"1998","journal-title":"J Periodontal Res"},{"issue":"7","key":"10.1016\/j.archoralbio.2016.09.014_bib0575","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1902\/jop.2001.72.7.849","article-title":"The expression of plasminogen activator system in a rat model of periodontal wound healing","volume":"72","author":"Xiao","year":"2001","journal-title":"J Periodontol"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0580","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1600-0765.1997.tb00539.x","article-title":"Effect of tension-force on plasminogen activator activity from human periodontal ligament cells","volume":"32","author":"Yamaguchi","year":"1997","journal-title":"J Periodontal Res"},{"issue":"3","key":"10.1016\/j.archoralbio.2016.09.014_bib0585","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1034\/j.1600-051x.2000.027003149.x","article-title":"Detection of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 2(PAI-2) in gingival crevicular fluid from healthy, gingivitis and periodontitis patients","volume":"27","author":"Yin","year":"2000","journal-title":"J Clin Periodontol"},{"issue":"5","key":"10.1016\/j.archoralbio.2016.09.014_bib0590","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1242\/dev.126.5.903","article-title":"Extracellular proteolysis alters tooth development in transgenic mice expressing urokinase-type plasminogen activator in the enamel organ","volume":"126","author":"Zhou","year":"1999","journal-title":"Development"},{"issue":"2","key":"10.1016\/j.archoralbio.2016.09.014_bib0595","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1055\/s-0038-1651569","article-title":"Cytokine regulation of the synthesis of plasminogen activator inhibitor-2 by human vascular endothelial cells. Comparison with plasminogen activator inhibitor-1 synthesis","volume":"69","author":"Zoellner","year":"1993","journal-title":"Thromb Haemost"}],"container-title":["Archives of Oral Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996916302758?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003996916302758?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T21:03:51Z","timestamp":1718831031000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003996916302758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":119,"alternative-id":["S0003996916302758"],"URL":"https:\/\/doi.org\/10.1016\/j.archoralbio.2016.09.014","relation":{},"ISSN":["0003-9969"],"issn-type":[{"type":"print","value":"0003-9969"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relevance of the plasminogen system in physiology, pathology, and regeneration of oral tissues \u2013 From the perspective of dental specialties","name":"articletitle","label":"Article Title"},{"value":"Archives of Oral Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.archoralbio.2016.09.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}