{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T14:17:45Z","timestamp":1782310665171,"version":"3.54.5"},"reference-count":11,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Medical Research"],"published-print":{"date-parts":[[2004,1]]},"DOI":"10.1016\/j.arcmed.2003.06.005","type":"journal-article","created":{"date-parts":[[2004,2,21]],"date-time":"2004-02-21T05:23:03Z","timestamp":1077340983000},"page":"31-35","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"title":["Down syndrome:"],"prefix":"10.1016","volume":"35","author":[{"given":"Maina P","family":"Kava","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milind S","family":"Tullu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamta N","family":"Muranjan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.M","family":"Girisha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arcmed.2003.06.005_BIB1","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0031-3955(16)38548-0","article-title":"Down syndrome","volume":"40","author":"Hayes","year":"1993","journal-title":"Pediatr Clin North Am"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF02823883","article-title":"Optimal care for children with Down syndrome in India","volume":"63","author":"Verma","year":"1996","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB3","series-title":"Recent advances in pediatrics\u2014Special volume 9: Neurology","first-page":"1","article-title":"Down syndrome","author":"Kumar","year":"2001"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB4","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1136\/jmg.33.2.89","article-title":"Down syndrome in sub-Saharan Africa","volume":"33","author":"Christianson","year":"1996","journal-title":"J Med Genet"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB5","series-title":"Birth defects encyclopedia","first-page":"391","article-title":"Chromosome 21, trisomy 21","author":"Fryns","year":"1990"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB6","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/BF02726619","article-title":"Genetic analysis of a group of mentally retarded children","volume":"56","author":"Krishnan","year":"1989","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB7","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/BF02751287","article-title":"Down syndrome in Ahmedabad: karyotype analysis in 60 cases","volume":"54","author":"Murthy","year":"1987","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB8","first-page":"218","article-title":"Frequency of trisomy 21, translocation, mosaicism and familial cases of Down's syndrome in Bombay","volume":"73","author":"Krishna Murthy","year":"1981","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB9","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1007\/BF02723953","article-title":"Burden of genetic disorders in India","volume":"67","author":"Verma","year":"2000","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB10","series-title":"Smith's recognizable patterns of human malformations","first-page":"8","article-title":"Down syndrome (Trisomy 21 syndrome)","author":"Jones","year":"1997"},{"key":"10.1016\/j.arcmed.2003.06.005_BIB11","first-page":"188","article-title":"Morgagni hernia with Down syndrome: a rare association\u2014case report and review of literature","volume":"47","author":"Parmar","year":"2001","journal-title":"J Postgrad Med"}],"container-title":["Archives of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440903001334?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440903001334?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T19:28:06Z","timestamp":1759260486000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0188440903001334"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,1]]}},"alternative-id":["S0188440903001334"],"URL":"https:\/\/doi.org\/10.1016\/j.arcmed.2003.06.005","relation":{},"ISSN":["0188-4409"],"issn-type":[{"value":"0188-4409","type":"print"}],"subject":[],"published":{"date-parts":[[2004,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Down syndrome:","name":"articletitle","label":"Article Title"},{"value":"Archives of Medical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arcmed.2003.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 IMSS. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}