{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:18:17Z","timestamp":1791141497672,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Medical Research"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.arcmed.2004.11.003","type":"journal-article","created":{"date-parts":[[2005,3,18]],"date-time":"2005-03-18T09:42:44Z","timestamp":1111138964000},"page":"83-86","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":132,"title":["Successful Treatment of Naegleria fowleri Meningoencephalitis by Using Intravenous Amphotericin B, Fluconazole and Rifampicin"],"prefix":"10.1016","volume":"36","author":[{"given":"Jes\u00fas","family":"Vargas-Zepeda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro V.","family":"G\u00f3mez-Alcal\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Alfonso","family":"V\u00e1zquez-Morales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Licea-Amaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan F.","family":"De Jonckheere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Lares-Villa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arcmed.2004.11.003_bib1","first-page":"153","article-title":"Naegleria fowleri: a free living amoeba of emerging medical importance","volume":"31","author":"Parija","year":"1999","journal-title":"J Commun Dis"},{"key":"10.1016\/j.arcmed.2004.11.003_bib2","first-page":"470","article-title":"Naegleria meningitis: a rare survival","volume":"50","author":"Jain","year":"2002","journal-title":"Neurol India"},{"key":"10.1016\/j.arcmed.2004.11.003_bib3","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0303-8467(93)90132-Z","article-title":"Successful treatment of amoebic meningoencephalitis in Chinese living in Hong Kong","volume":"95","author":"Wang","year":"1993","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1016\/j.arcmed.2004.11.003_bib4","first-page":"333","article-title":"Acute primary meningoencephalitis from entamoeba Naegleria fowleri. Report of a clinical case with a favourable outcome","volume":"15","author":"Loschiavo","year":"1993","journal-title":"Acta Neurol (Napoli)"},{"key":"10.1016\/j.arcmed.2004.11.003_bib5","first-page":"112","article-title":"The fifth non-lethal case of primary amoebic meningoencephalitis","volume":"74","author":"Poungvarin","year":"1991","journal-title":"J Med Assoc Thai"},{"key":"10.1016\/j.arcmed.2004.11.003_bib6","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1001\/archinte.1991.00400060121021","article-title":"Successful treatment of primary amebic meningoencephalitis","volume":"151","author":"Brown","year":"1991","journal-title":"Arch Intern Med"},{"issue":"6","key":"10.1016\/j.arcmed.2004.11.003_bib7","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1056\/NEJM198202113060607","article-title":"Successful treatment of primary amebic meningoencephalitis","volume":"306","author":"Seidel","year":"1982","journal-title":"N Engl J Med"},{"issue":"7804","key":"10.1016\/j.arcmed.2004.11.003_bib8","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/S0140-6736(73)92242-3","article-title":"Primary amoebic meningoencephalitis","volume":"1","author":"Anderson","year":"1973","journal-title":"Lancet"},{"issue":"696","key":"10.1016\/j.arcmed.2004.11.003_bib9","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1136\/bmj.1.5696.596","article-title":"Primary amoebic meningoencephalitis in Britain","volume":"1","author":"Apley","year":"1970","journal-title":"Br Med J"},{"key":"10.1016\/j.arcmed.2004.11.003_bib10","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1001\/archinte.1992.00400180166033","article-title":"Amebic encephalitis unlikely","volume":"152","author":"Martinez","year":"1992","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.arcmed.2004.11.003_bib11","first-page":"13","article-title":"Free-living amoebae infections in Mexico. Proc. IX International Meeting on the Biology and Pathogenicity on Free-Living Amoebae","author":"Lares-Villa","year":"2001"},{"key":"10.1016\/j.arcmed.2004.11.003_bib12","unstructured":"Rodr\u00edguez P\u00e9rez EG. Meningoencefalitis por Naegleria fowleri, informe de un caso. Infectolog\u00eda (M\u00e9x) 1984;4:263\u2013266."},{"key":"10.1016\/j.arcmed.2004.11.003_bib13","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1645\/GE-87R","article-title":"Activities of therapeutic agents against Naegleria fowleri in vitro and in a mouse model of primary amebic meningoencephalitis","volume":"89","author":"Goswick","year":"2003","journal-title":"J Parasitol"},{"key":"10.1016\/j.arcmed.2004.11.003_bib14","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1128\/CMR.15.3.342-354.2002","article-title":"Cultivation of pathogenic and opportunistic free-living amebas","volume":"15","author":"Schuster","year":"2002","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.arcmed.2004.11.003_bib15","first-page":"1","article-title":"Free-living amebas and the immune deficient host. Proc. IX International Meeting on the Biology and Pathogenicity on Free-Living Amoeba","author":"Mart\u00ednez","year":"2001"},{"key":"10.1016\/j.arcmed.2004.11.003_bib16","first-page":"309","article-title":"A century of research on the amoeboflagellate genus Naegleria","volume":"41","author":"De Jonckheere","year":"2002","journal-title":"Acta Protozool"},{"issue":"SS-08","key":"10.1016\/j.arcmed.2004.11.003_bib17","first-page":"1","article-title":"Surveillance for waterborne-disease outbreaks\u2014United States, 1999-2000","volume":"51","author":"Lee","year":"2002","journal-title":"MMWR"},{"issue":"SS-04","key":"10.1016\/j.arcmed.2004.11.003_bib18","first-page":"1","article-title":"Surveillance for waterborne disease outbreaks\u2014United States, 1997-1998","volume":"49","author":"Barwick","year":"2000","journal-title":"MMWR"},{"issue":"SS-5","key":"10.1016\/j.arcmed.2004.11.003_bib19","first-page":"1","article-title":"Surveillance for waterborne disease outbreaks\u2014United States, 1995-1996","volume":"47","author":"Levy","year":"1998","journal-title":"MMWR"},{"issue":"SS-1","key":"10.1016\/j.arcmed.2004.11.003_bib20","first-page":"1","article-title":"Surveillance for waterborne disease outbreaks\u2014United States, 1993-1994","volume":"45","author":"Kramer","year":"1996","journal-title":"MMWR"},{"issue":"SS-05","key":"10.1016\/j.arcmed.2004.11.003_bib21","first-page":"1","article-title":"Surveillance for waterborne disease outbreaks\u2014United States, 1991-1992","volume":"42","author":"Anon","year":"1993","journal-title":"MMWR"},{"key":"10.1016\/j.arcmed.2004.11.003_bib22","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1645\/0022-3395(2000)086[0050:ALMSOT]2.0.CO;2","article-title":"A light microscopy study of the migration of Naegleria fowleri from the nasal submucosa to the central nervous system during the early stage of primary amebic meningoencephalitis in mice","volume":"86","author":"Jarolim","year":"2000","journal-title":"J Parasitol"},{"key":"10.1016\/j.arcmed.2004.11.003_bib23","unstructured":"Lares-Villa F, Guerrero-Dumas AM, L\u00f3pez-Osorio A. Estudio protozool\u00f3gico (Subphylum SARCODINA, Clase LOBOSEA) en ambientes acu\u00e1ticos de la regi\u00f3n del Valle del Yaqui, Sonora, M\u00e9xico. ITSON-DIEP (Mex) 1997;2:47\u201355."},{"issue":"suppl","key":"10.1016\/j.arcmed.2004.11.003_bib24","first-page":"25S","article-title":"Epidemiology of free-living ameba infections","volume":"37","author":"Visvesvara","year":"1990","journal-title":"J Protozool"},{"key":"10.1016\/j.arcmed.2004.11.003_bib25","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/BF00937109","article-title":"Seasonal distribution of pathogenic free-living amebae in Oklahoma waters","volume":"81","author":"John","year":"1995","journal-title":"Parasitol Res"},{"key":"10.1016\/j.arcmed.2004.11.003_bib26","first-page":"33","article-title":"Estudio de la presencia de amibas de vida libre en agua entubada de la localidad de San Ignacio R\u00edo Muerto, Sonora. En: Memorias de la VIII Reuni\u00f3n de Investigaci\u00f3n en Salud en el Estado de Sonora","volume":"2","author":"Herrera-Andrade","year":"2002","journal-title":"Acta M\u00e9d Sonora (Mex)"},{"issue":"8043","key":"10.1016\/j.arcmed.2004.11.003_bib27","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/S0140-6736(77)90813-3","article-title":"Growth inhibition of Naegleria fowleri by tetracycline, rifamycin, and miconazole","volume":"2","author":"Thong","year":"1977","journal-title":"Lancet"},{"key":"10.1016\/j.arcmed.2004.11.003_bib28","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1089\/jop.1998.14.459","article-title":"Comparison of fluconazole pharmacokinetics in serum, aqueous humor, vitreous humor, and cerebrospinal fluid following a single dose and at steady state","volume":"14","author":"Mian","year":"1998","journal-title":"J Ocul Pharmacol Ther"},{"key":"10.1016\/j.arcmed.2004.11.003_bib29","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1023\/A:1016048100712","article-title":"Fluconazole distribution to the brain: a crossover study in freely-moving rats using in vivo microdialysis","volume":"13","author":"Yang","year":"1996","journal-title":"Pharm Res"},{"key":"10.1016\/j.arcmed.2004.11.003_bib30","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1097\/01.CCM.0000074724.71242.88","article-title":"Fluconazole improves survival in septic shock: a randomized double-blind prospective study","volume":"31","author":"Jacobs","year":"2003","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arcmed.2004.11.003_bib31","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1177\/106002809603001209","article-title":"Fluconazole and amphotericin B for cryptococcal meningitis","volume":"30","author":"Clark","year":"1996","journal-title":"Ann Pharmacother"},{"issue":"suppl","key":"10.1016\/j.arcmed.2004.11.003_bib32","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/j.1550-7408.2003.tb00617.x","article-title":"Genetic variations in the internal transcribed spacer and mitochondrial small subunit rRNA gene of Naegleria spp","volume":"50","author":"Zhou","year":"2003","journal-title":"J Eukaryot Microbiol"}],"container-title":["Archives of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440904001225?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440904001225?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T19:28:53Z","timestamp":1759260533000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0188440904001225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0188440904001225"],"URL":"https:\/\/doi.org\/10.1016\/j.arcmed.2004.11.003","relation":{},"ISSN":["0188-4409"],"issn-type":[{"value":"0188-4409","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Successful Treatment of Naegleria fowleri Meningoencephalitis by Using Intravenous Amphotericin B, Fluconazole and Rifampicin","name":"articletitle","label":"Article Title"},{"value":"Archives of Medical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arcmed.2004.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005  Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}