{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T23:28:54Z","timestamp":1785281334846,"version":"3.55.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Medical Research"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1016\/j.arcmed.2014.04.006","type":"journal-article","created":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T16:00:22Z","timestamp":1399651222000},"page":"325-330","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"title":["Oral Magnesium Supplementation Decreases C-reactive Protein Levels in Subjects with Prediabetes and Hypomagnesemia: A Clinical Randomized Double-blind Placebo-controlled Trial"],"prefix":"10.1016","volume":"45","author":[{"given":"Luis E.","family":"Simental-Mend\u00eda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha","family":"Rodr\u00edguez-Mor\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Guerrero-Romero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arcmed.2014.04.006_bib1","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/sj.ijo.0801954","article-title":"Relationship between serum magnesium levels and C-reactive protein concentration, in non-diabetic, non-hypertensive obese subjects","volume":"26","author":"Guerrero-Romero","year":"2002","journal-title":"Int J Obes Relat Metab Disord"},{"key":"10.1016\/j.arcmed.2014.04.006_bib2","first-page":"189","article-title":"Elevated concentrations of TNF-alpha are related to low serum magnesium levels in obese subjects","volume":"17","author":"Rodriguez-Mor\u00e1n","year":"2004","journal-title":"Magnes Res"},{"key":"10.1016\/j.arcmed.2014.04.006_bib3","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/dmrr.644","article-title":"Hypomagnesemia, oxidative stress, inflammation, and metabolic syndrome","volume":"22","author":"Guerrero-Romero","year":"2006","journal-title":"Diabetes Metab Res"},{"key":"10.1016\/j.arcmed.2014.04.006_bib4","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1097\/MAJ.0b013e3181aaee4d","article-title":"Neurogenic inflammation and cardiac dysfunction due to hypomagnesemia","volume":"338","author":"Kramer","year":"2009","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.arcmed.2014.04.006_bib5","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1080\/07315724.2005.10719461","article-title":"Dietary magnesium and C-reactive protein levels","volume":"24","author":"King","year":"2005","journal-title":"J Am Coll Nutr"},{"key":"10.1016\/j.arcmed.2014.04.006_bib6","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s005920200036","article-title":"Low serum magnesium levels and metabolic syndrome","volume":"39","author":"Guerrero-Romero","year":"2002","journal-title":"Acta Diabetol"},{"key":"10.1016\/j.arcmed.2014.04.006_bib7","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.2337\/diacare.28.6.1438","article-title":"Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women","volume":"28","author":"Song","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.arcmed.2014.04.006_bib8","first-page":"32","article-title":"Magnesium intake and serum C-reactive protein levels in children","volume":"20","author":"King","year":"2007","journal-title":"Magnes Res"},{"key":"10.1016\/j.arcmed.2014.04.006_bib9","doi-asserted-by":"crossref","first-page":"813","DOI":"10.2337\/diacare.27.3.813","article-title":"Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes","volume":"27","author":"Pickup","year":"2004","journal-title":"Diabetes Care"},{"key":"10.1016\/j.arcmed.2014.04.006_bib10","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1684\/mrh.2012.0322","article-title":"No positive effect of oral magnesium supplementation in the decreases of inflammation in subjects with prediabetes: a pilot study","volume":"25","author":"Simental-Mend\u00eda","year":"2012","journal-title":"Magnes Res"},{"key":"10.1016\/j.arcmed.2014.04.006_bib11","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.2337\/diacare.26.11.3160","article-title":"Follow up report on the diagnosis of diabetes mellitus","volume":"26","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.arcmed.2014.04.006_bib12","first-page":"355","article-title":"New data about the effect of oral physiological magnesium supplementation on several cardiovascular risk factors (lipids and blood pressure)","volume":"6","author":"Kisters","year":"1993","journal-title":"Magnes Res"},{"key":"10.1016\/j.arcmed.2014.04.006_bib13","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1161\/01.HYP.0000107251.49515.c2","article-title":"The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure","volume":"42","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.arcmed.2014.04.006_bib14","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/clinchem\/43.1.52","article-title":"Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications","volume":"43","author":"Macy","year":"1997","journal-title":"Clin Chem"},{"key":"10.1016\/j.arcmed.2014.04.006_bib15","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s00394-007-0655-x","article-title":"Magnesium and C-reactive protein in heart failure: an anti-inflammatory effect of magnesium administration?","volume":"46","author":"Almoznino-Sarafian","year":"2007","journal-title":"Eur J Nutr"},{"key":"10.1016\/j.arcmed.2014.04.006_bib16","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1080\/07315724.2005.10719461","article-title":"Dietary magnesium and C-reactive protein levels","volume":"24","author":"King","year":"2005","journal-title":"J Am Coll Nutr"},{"key":"10.1016\/j.arcmed.2014.04.006_bib17","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1016\/S0024-3205(98)00455-X","article-title":"Exacerbated immune stress response during experimental magnesium deficiency results from abnormal cell calcium homeostasis","volume":"63","author":"Malpuech-Brug\u00e8re","year":"1998","journal-title":"Life Sci"},{"key":"10.1016\/j.arcmed.2014.04.006_bib18","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0925-4439(00)00018-1","article-title":"Inflammatory response following acute magnesium deficiency in the rat","volume":"1501","author":"Malpuech-Brug\u00e8re","year":"2000","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.arcmed.2014.04.006_bib19","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1161\/01.RES.74.5.1009","article-title":"Blockade of cardiac inflammation in Mg2+ deficiency by substance P receptor inhibition","volume":"74","author":"Weglicki","year":"1994","journal-title":"Circ Res"},{"key":"10.1016\/j.arcmed.2014.04.006_bib20","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/jn\/134.4.913","article-title":"Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in Hispanic and non-Hispanic white elders","volume":"134","author":"Gao","year":"2004","journal-title":"J Nutr"},{"key":"10.1016\/j.arcmed.2014.04.006_bib21","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.7754\/Clin.Lab.2012.121226","article-title":"Weight reduction is associated with decreased CRP levels","volume":"59","author":"Larsson","year":"2013","journal-title":"Clin Lab"},{"key":"10.1016\/j.arcmed.2014.04.006_bib22","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.3945\/jn.108.097188","article-title":"Modulation of C-reactive protein, tumor necrosis factor-alpha, and adiponectin by diet, exercise, and weight loss","volume":"138","author":"Puglisi","year":"2008","journal-title":"J Nutr"},{"key":"10.1016\/j.arcmed.2014.04.006_bib23","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1001\/jama.293.1.43","article-title":"Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial","volume":"293","author":"Dansinger","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.arcmed.2014.04.006_bib24","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1001\/archinte.167.1.31","article-title":"The effect of weight loss on C-reactive protein: a systematic review","volume":"167","author":"Selvin","year":"2007","journal-title":"Arch Intern Med"}],"container-title":["Archives of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440914000757?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440914000757?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T19:42:29Z","timestamp":1759261349000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0188440914000757"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["S0188440914000757"],"URL":"https:\/\/doi.org\/10.1016\/j.arcmed.2014.04.006","relation":{},"ISSN":["0188-4409"],"issn-type":[{"value":"0188-4409","type":"print"}],"subject":[],"published":{"date-parts":[[2014,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oral Magnesium Supplementation Decreases C-reactive Protein Levels in Subjects with Prediabetes and Hypomagnesemia: A Clinical Randomized Double-blind Placebo-controlled Trial","name":"articletitle","label":"Article Title"},{"value":"Archives of Medical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arcmed.2014.04.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 IMSS. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}