{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:05:04Z","timestamp":1759334704655,"version":"build-2065373602"},"reference-count":43,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004564","name":"Ministarstvo Prosvete, Nauke i Tehnolo\u0161kog Razvoja","doi-asserted-by":"publisher","award":["175038","175089"],"award-info":[{"award-number":["175038","175089"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Medical Research"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.arcmed.2018.04.015","type":"journal-article","created":{"date-parts":[[2018,5,10]],"date-time":"2018-05-10T08:31:39Z","timestamp":1525941099000},"page":"101-108","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cytokine Gene Polymorphism Profiles in Kidney Transplant Patients - Association of +1188A\/C RS3212227 SNP in the IL12B Gene Prevents Delayed Graft Function"],"prefix":"10.1016","volume":"49","author":[{"given":"Vladimir","family":"Perovic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milos","family":"Markovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milica","family":"Kravljaca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emina","family":"Milosevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milica","family":"Djoric","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"Pravica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radomir","family":"Naumovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arcmed.2018.04.015_bib1","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/j.1600-6143.2010.03283.x","article-title":"Long-term renal allograft survival in the United States: a critical reappraisal","volume":"11","author":"Lamb","year":"2011","journal-title":"Am J Transplant"},{"key":"10.1016\/j.arcmed.2018.04.015_bib2","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1093\/ndt\/gfp782","article-title":"Genetic predictors of acute renal transplant rejection","volume":"25","author":"Goldfarb-Rumyantzev","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.arcmed.2018.04.015_bib3","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1111\/j.1600-6143.2011.03754.x","article-title":"Delayed graft function in the kidney transplant","volume":"11","author":"Siedlecki","year":"2011","journal-title":"Am J Transplant"},{"key":"10.1016\/j.arcmed.2018.04.015_bib4","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1093\/ndt\/gfn667","article-title":"Association between delayed graft function and allograft and patient survival: a systematic review and meta-analysis","volume":"24","author":"Yarlagadda","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.arcmed.2018.04.015_bib5","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.cytogfr.2008.11.006","article-title":"Cytokine and cytokine receptor gene polymorphisms and their functionality","volume":"20","author":"Smith","year":"2009","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.arcmed.2018.04.015_bib6","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/hmg\/1.5.353","article-title":"Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product","volume":"1","author":"Wilson","year":"1992","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.arcmed.2018.04.015_bib7","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/nm.3895","article-title":"IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases","volume":"21","author":"Teng","year":"2015","journal-title":"Nat Med"},{"key":"10.1016\/j.arcmed.2018.04.015_bib8","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1093\/hmg\/ddt034","article-title":"Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis","volume":"22","author":"Johnston","year":"2013","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.arcmed.2018.04.015_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-2370.1999.00122.x","article-title":"In\u00a0vitro production of IFN-gamma correlates with CA repeat polymorphism in the human IFN-gamma gene","volume":"26","author":"Pravica","year":"1999","journal-title":"Eur J Immunogenet"},{"key":"10.1016\/j.arcmed.2018.04.015_bib10","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/imm.12362","article-title":"Clinical implications of interferon-gamma genetic and epigenetic variants","volume":"143","author":"Smith","year":"2014","journal-title":"Immunology"},{"key":"10.1016\/j.arcmed.2018.04.015_bib11","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/S0198-8859(00)00167-1","article-title":"A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production","volume":"61","author":"Pravica","year":"2000","journal-title":"Hum Immunol"},{"key":"10.1016\/j.arcmed.2018.04.015_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2370.1997.tb00001.x","article-title":"An investigation of polymorphism in the interleukin-10 gene promoter","volume":"24","author":"Turner","year":"1997","journal-title":"Eur J Immunogenet"},{"key":"10.1016\/j.arcmed.2018.04.015_bib13","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.clinbiochem.2015.07.016","article-title":"Genetic polymorphisms in the immune response: A focus on kidney transplantation","volume":"49","author":"Stojanova","year":"2016","journal-title":"Clin Biochem"},{"key":"10.1016\/j.arcmed.2018.04.015_bib14","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/j.1432-2277.2010.01205.x","article-title":"Racial and ethnic disparities in kidney transplantation","volume":"24","author":"Malek","year":"2011","journal-title":"Transpl Int"},{"key":"10.1016\/j.arcmed.2018.04.015_bib15","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/cts.12000","article-title":"Distinctive frequencies of\u00a0+874T\/A IFN-gamma gene polymorphism in a healthy Serbian population","volume":"5","author":"Popadic","year":"2012","journal-title":"Clin Transl Sci"},{"key":"10.1016\/j.arcmed.2018.04.015_bib16","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.1755-0998.2010.02847.x","article-title":"Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows","volume":"10","author":"Excoffier","year":"2010","journal-title":"Mol Ecol Resour"},{"key":"10.1016\/j.arcmed.2018.04.015_bib17","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.2174\/092986732319160719192019","article-title":"Acute Renal Failure in Transplanted Kidneys","volume":"23","author":"Basta-Jovanovic","year":"2016","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.arcmed.2018.04.015_bib18","doi-asserted-by":"crossref","first-page":"11684","DOI":"10.1038\/srep11684","article-title":"Biomarkers of delayed graft function as a form of acute kidney injury in kidney transplantation","volume":"5","author":"Malyszko","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.arcmed.2018.04.015_bib19","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1097\/01.TP.0000114291.01231.DD","article-title":"Cytokines and chronic rejection: a study in kidney transplant long-term survivors","volume":"77","author":"Uboldi de Capei","year":"2004","journal-title":"Transplantation"},{"key":"10.1016\/j.arcmed.2018.04.015_bib20","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.1365-2249.2008.03632.x","article-title":"The value of serum neopterin, interferon-gamma levels and interleukin-12B polymorphisms in predicting acute renal allograft rejection","volume":"152","author":"Chin","year":"2008","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.arcmed.2018.04.015_bib21","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/j.transproceed.2014.06.019","article-title":"The impact of interleukin 12B (1188A>C), interleukin 16 (-295T>C), and interleukin 18 (607C>A, 137G>C) gene polymorphisms on long-term renal transplant function and recipient outcomes","volume":"46","author":"Pawlus","year":"2014","journal-title":"Transplant Proc"},{"key":"10.1016\/j.arcmed.2018.04.015_bib22","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.transproceed.2008.12.002","article-title":"Impact of a polymorphism in the IL-12p40 gene on the outcome of kidney transplantation","volume":"41","author":"Hoffmann","year":"2009","journal-title":"Transplant Proc"},{"key":"10.1016\/j.arcmed.2018.04.015_bib23","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1097\/TP.0b013e3181ea391e","article-title":"Graft inflammation and histologic indicators of kidney chronic allograft failure: low-expressing interleukin-10 genotypes cannot be ignored","volume":"90","author":"Khan","year":"2010","journal-title":"Transplantation"},{"key":"10.1016\/j.arcmed.2018.04.015_bib24","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.imlet.2013.09.028","article-title":"Genetic variations in IL6 and IL12B decreasing the risk for psoriasis","volume":"156","author":"Boca","year":"2013","journal-title":"Immunol Lett"},{"key":"10.1016\/j.arcmed.2018.04.015_bib25","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1038\/sj.gene.6364213","article-title":"Taq-I polymorphism in 3'UTR of the IL-12B and association with IL-12p40 production from human PBMC","volume":"6","author":"Stanilova","year":"2005","journal-title":"Genes Immun"},{"key":"10.1016\/j.arcmed.2018.04.015_bib26","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1365-3083.2012.02736.x","article-title":"Single nucleotide polymorphism in the interleukin 12B gene is associated with risk for breast cancer development","volume":"76","author":"Kaarvatn","year":"2012","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.arcmed.2018.04.015_bib27","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nri1001","article-title":"Interleukin-12 and the regulation of innate resistance and adaptive immunity","volume":"3","author":"Trinchieri","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.arcmed.2018.04.015_bib28","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.immuni.2008.03.001","article-title":"Th17 cell differentiation: the long and winding road","volume":"28","author":"McGeachy","year":"2008","journal-title":"Immunity"},{"key":"10.1016\/j.arcmed.2018.04.015_bib29","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/MOT.0b013e32834ef4e4","article-title":"Significance of T helper 17 immunity in transplantation","volume":"17","author":"Abadja","year":"2012","journal-title":"Curr Opin Organ Transplant"},{"key":"10.1016\/j.arcmed.2018.04.015_bib30","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1432-2277.2010.01157.x","article-title":"T helper 1, 2 and 17 cell subsets in renal transplant patients with delayed graft function","volume":"24","author":"Loverre","year":"2011","journal-title":"Transpl Int"},{"key":"10.1016\/j.arcmed.2018.04.015_bib31","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0966-3274(97)80038-X","article-title":"Interleukin-12 p40 m-RNA expression in human kidney allograft biopsies","volume":"5","author":"de Mattos","year":"1997","journal-title":"Transpl Immunol"},{"key":"10.1016\/j.arcmed.2018.04.015_bib32","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1399-0012.2004.00185.x","article-title":"Pre-transplant elevations of interleukin-12 and interleukin-10 are associated with acute rejection after renal transplantation","volume":"18","author":"Fitzgerald","year":"2004","journal-title":"Clin Transplant"},{"key":"10.1016\/j.arcmed.2018.04.015_bib33","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.trim.2013.10.001","article-title":"Inhibiting cardiac allograft rejection with interleukin-35 therapy combined with decitabine treatment in mice","volume":"29","author":"Guo","year":"2013","journal-title":"Transpl Immunol"},{"key":"10.1016\/j.arcmed.2018.04.015_bib34","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.intimp.2015.10.025","article-title":"IL-35 inhibits acute graft-versus-host disease in a mouse model","volume":"29","author":"Zhang","year":"2015","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.arcmed.2018.04.015_bib35","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1007\/s10753-017-0582-9","article-title":"IL-35 Pretreatment Alleviates Lipopolysaccharide-Induced Acute Kidney Injury in Mice by Inhibiting NF-kappaB Activation","volume":"40","author":"Hu","year":"2017","journal-title":"Inflammation"},{"key":"10.1016\/j.arcmed.2018.04.015_bib36","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.cytogfr.2015.07.013","article-title":"Interleukin 35: Critical regulator of immunity and lymphocyte-mediated diseases","volume":"26","author":"Egwuagu","year":"2015","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.arcmed.2018.04.015_bib37","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.it.2006.11.002","article-title":"IL-12p40: an inherently agonistic cytokine","volume":"28","author":"Cooper","year":"2007","journal-title":"Trends Immunol"},{"key":"10.1016\/j.arcmed.2018.04.015_bib38","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.trim.2011.04.004","article-title":"Donor or recipient TNF-A -308G\/A polymorphism and acute rejection of renal allograft: A meta-analysis","volume":"25","author":"Hu","year":"2011","journal-title":"Transpl Immunol"},{"key":"10.1016\/j.arcmed.2018.04.015_bib39","doi-asserted-by":"crossref","first-page":"6043","DOI":"10.1007\/s11033-013-2714-0","article-title":"Association between interferon gamma\u00a0+874 T>A polymorphism and acute renal allograft rejection: evidence from published studies","volume":"40","author":"Ge","year":"2013","journal-title":"Mol Biol Rep"},{"key":"10.1016\/j.arcmed.2018.04.015_bib40","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1093\/ndt\/gfn185","article-title":"Association between cytokine gene polymorphisms and outcomes in renal transplantation: a meta-analysis of individual patient data","volume":"23","author":"Thakkinstian","year":"2008","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.arcmed.2018.04.015_bib41","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3109\/0886022X.2015.1106770","article-title":"Interleukin-10-1082 G\/a polymorphism and acute renal graft rejection: a meta-analysis","volume":"38","author":"Hu","year":"2016","journal-title":"Ren Fail"},{"key":"10.1016\/j.arcmed.2018.04.015_bib42","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/sj.gene.6363656","article-title":"Microsatellite alleles and single nucleotide polymorphisms (SNP) combine to form four major haplotype families at the human interleukin-10 (IL-10) locus","volume":"1","author":"Eskdale","year":"1999","journal-title":"Genes Immun"},{"key":"10.1016\/j.arcmed.2018.04.015_bib43","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1620\/tjem.240.15","article-title":"The Polymorphism rs3024505 (C\/T) Downstream of the IL10 Gene Is Associated with Crohn's Disease in Serbian Patients with Inflammatory Bowel Disease","volume":"240","author":"Mijac","year":"2016","journal-title":"Tohoku J Exp Med"}],"container-title":["Archives of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440918301553?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440918301553?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T19:45:56Z","timestamp":1759261556000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0188440918301553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["S0188440918301553"],"URL":"https:\/\/doi.org\/10.1016\/j.arcmed.2018.04.015","relation":{},"ISSN":["0188-4409"],"issn-type":[{"type":"print","value":"0188-4409"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cytokine Gene Polymorphism Profiles in Kidney Transplant Patients - Association of +1188A\/C RS3212227 SNP in the IL12B Gene Prevents Delayed Graft Function","name":"articletitle","label":"Article Title"},{"value":"Archives of Medical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arcmed.2018.04.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 IMSS. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}