{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:00:54Z","timestamp":1777532454214,"version":"3.51.4"},"reference-count":43,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Medical Research"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.arcmed.2018.07.002","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T20:33:40Z","timestamp":1532032420000},"page":"182-190","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Serum Amyloid A, Paraoxonase-1 Activity, and Apolipoprotein Concentrations as Biomarkers of Subclinical Atherosclerosis Risk in Adrenal Incidentaloma Patients"],"prefix":"10.1016","volume":"49","author":[{"given":"Narin Nasiroglu","family":"Imga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Canan","family":"Topcuoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilek","family":"Berker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Turan","family":"Turhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arcmed.2018.07.002_bib1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1530\/eje.0.1490273","article-title":"Prevalence and natural history of adrenal incidentalomas","volume":"149","author":"Barzon","year":"2003","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.arcmed.2018.07.002_bib2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0889-8529(05)70115-8","article-title":"Subclinical Cushing\u2019s syndrome","volume":"29","author":"Reincke","year":"2000","journal-title":"Endocrinol Metab Clin North Am"},{"key":"10.1016\/j.arcmed.2018.07.002_bib3","first-page":"637","article-title":"A survey on adrenal incidentaloma in Italy","volume":"85","author":"Mantero","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.arcmed.2018.07.002_bib4","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1530\/EJE-16-0467","article-title":"Management of adrenal incidentalomas: European society of endocrinology clinical practice guideline in collaboration with the european network for the study of adrenal tumors","volume":"175","author":"Fassnacht","year":"2016","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.arcmed.2018.07.002_bib5","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1530\/eje.0.1460061","article-title":"Development of overt Cushing's syndrome in patients with adrenal incidentaloma","volume":"146","author":"Barzon","year":"2002","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.arcmed.2018.07.002_bib6","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S2213-8587(14)70080-4","article-title":"Subclinical Cushing's syndrome and cardiovascular disease","volume":"2","author":"Anagnostis","year":"2014","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.arcmed.2018.07.002_bib7","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/S2213-8587(13)70211-0","article-title":"Cardiovascular events and mortality in patients with adrenal incidentalomas that are either non-secreting or associated with intermediate phenotype or subclinical Cushing's syndrome: a 15-year retrospective study","volume":"2","author":"Di Dalmazi","year":"2014","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.arcmed.2018.07.002_bib8","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1530\/eje.0.1480213","article-title":"Anthropometric, haemodynamic, humoral and hormonal evaluation in patients with incidental adrenocortical adenomas before and after surgery","volume":"148","author":"Bernini","year":"2003","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.arcmed.2018.07.002_bib9","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1210\/jcem.87.3.8277","article-title":"Adrenal incidentaloma: a new cause of the metabolic syndrome?","volume":"87","author":"Terzolo","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.arcmed.2018.07.002_bib10","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/j.metabol.2010.01.007","article-title":"Insulin resistance and metabolic syndrome in patients with nonfunctioning adrenal incidentalomas: a cause-effect relationship?","volume":"59","author":"Peppa","year":"2010","journal-title":"Metabolism"},{"key":"10.1016\/j.arcmed.2018.07.002_bib11","first-page":"e37635","article-title":"The Relationship Between Increased Epicardial Fat Thickness and Left Ventricular Hypertrophy and Carotid Intima-Media Thickness in Patients With Nonfunctional Adrenal Incidentaloma","volume":"14","author":"Imga","year":"2016","journal-title":"Int J Clin Endocrinol Metab"},{"key":"10.1016\/j.arcmed.2018.07.002_bib12","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s40618-014-0106-5","article-title":"Non-functioning adrenal incidentalomas are associated with higher hypertension prevalence and higher risk of atherosclerosis","volume":"37","author":"Tuna","year":"2014","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.arcmed.2018.07.002_bib13","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1155\/2013\/816189","article-title":"Reduced paraoxonase 1 activity as a marker for severe coronary artery disease","volume":"35","author":"Zhou","year":"2013","journal-title":"Dis Markers"},{"key":"10.1016\/j.arcmed.2018.07.002_bib14","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1161\/hq0901.094247","article-title":"Paraoxonase status in coronary heart disease","volume":"21","author":"Mackness","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.arcmed.2018.07.002_bib15","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1161\/01.ATV.0000227472.70734.ad","article-title":"Reciprocal and coordinate regulation of serum amyloid A versus apolipoprotein AI and paraoxonase-1 by inflammation in murine hepatocytes","volume":"26","author":"Han","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.arcmed.2018.07.002_bib16","first-page":"2013","article-title":"Paired measurements of paraoxonase 1 and serum amyloid A as useful disease markers","volume":"22","author":"Kotani","year":"2013","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.arcmed.2018.07.002_bib17","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1007\/s00109-005-0030-4","article-title":"Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL","volume":"84","author":"Zannis","year":"2006","journal-title":"J Mol Med (Berl)"},{"key":"10.1016\/j.arcmed.2018.07.002_bib18","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S1568-9972(01)00018-0","article-title":"High-density lipoprotein-associated apolipoprotein AI: the missing link between infection and chronic inflammation?","volume":"1","author":"Burger","year":"2002","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.arcmed.2018.07.002_bib19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.atherosclerosis.2009.12.036","article-title":"Lipoprotein (a) and ischemic heart disease\u2014a causal association? A review","volume":"211","author":"Kamstrup","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.arcmed.2018.07.002_bib20","doi-asserted-by":"crossref","first-page":"2844","DOI":"10.1093\/eurheartj\/ehq386","article-title":"Lipoprotein (a) as a cardiovascular risk factor: current status","volume":"31","author":"Nordestgaard","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.arcmed.2018.07.002_bib21","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1002\/clc.4960270503","article-title":"Lipoprotein (a): new insights into mechanisms of atherogenesis and thrombosis","volume":"27","author":"Deb","year":"2004","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.arcmed.2018.07.002_bib22","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1210\/jc.2007-1780","article-title":"Dehydroepiandrosterone sulfate in the assessment of the hypothalamic-pituitary-adrenal axis","volume":"93","author":"Fischli","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.arcmed.2018.07.002_bib23","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1161\/CIRCULATIONAHA.109.848911","article-title":"Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt\/GSK3-\u03b2\/NFAT axis","volume":"120","author":"Bonnet","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.arcmed.2018.07.002_bib24","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1507\/endocrj.46.521","article-title":"A close association between insulin resistance and dehydroepiandrosterone sulfate in subjects with essential hypertension","volume":"46","author":"Suzuki","year":"1999","journal-title":"Endocr J"},{"key":"10.1016\/j.arcmed.2018.07.002_bib25","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.metabol.2011.06.005","article-title":"Circulating androgen levels are associated with subclinical atherosclerosis and arterial stiffness in healthy recently menopausal women","volume":"61","author":"Creatsa","year":"2012","journal-title":"Metabolism"},{"key":"10.1016\/j.arcmed.2018.07.002_bib26","doi-asserted-by":"crossref","first-page":"4985","DOI":"10.1210\/jc.2010-0143","article-title":"DHEA-S levels and cardiovascular disease mortality in postmenopausal women: results from the National Institutes of Health\u2014National Heart, Lung, and Blood Institute (NHLBI)-sponsored Women\u2019s Ischemia Syndrome Evaluation (WISE)","volume":"95","author":"Shufelt","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.arcmed.2018.07.002_bib27","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s12020-014-0387-7","article-title":"DHEAS for the prediction of subclinical Cushing\u2019s syndrome: perplexing or advantageous?","volume":"48","author":"Yener","year":"2015","journal-title":"Endocrine"},{"key":"10.1016\/j.arcmed.2018.07.002_bib28","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-2265.2010.03794.x","article-title":"Subclinical hypercortisolism: correlation between biochemical diagnostic criteria and clinical aspects","volume":"73","author":"Morelli","year":"2010","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.arcmed.2018.07.002_bib29","series-title":"Metabolik Sendrom Kilavuzu, Tuna Matbaacilik","first-page":"1","author":"Arslan","year":"2009"},{"key":"10.1016\/j.arcmed.2018.07.002_bib30","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge","volume":"18","author":"Friedewald","year":"1972","journal-title":"Clin Chem"},{"key":"10.1016\/j.arcmed.2018.07.002_bib31","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1056\/NEJMra043430","article-title":"Inflammation, atherosclerosis, and coronary artery disease","volume":"352","author":"Hansson","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arcmed.2018.07.002_bib32","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ymgme.2011.09.018","article-title":"Association between PON1 activity and coronary heart disease risk: a meta-analysis based on 43 studies","volume":"105","author":"Zhao","year":"2012","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.arcmed.2018.07.002_bib33","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1161\/01.CIR.103.13.1813","article-title":"High-sensitivity C-reactive protein","volume":"103","author":"Ridker","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.arcmed.2018.07.002_bib34","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1365-2265.2008.03306.x","article-title":"High plasma C-reactive protein (CRP) is related to low paraoxonase-I (PON-I) activity independently of high leptin and low adiponectin in type 2 diabetes mellitus","volume":"70","author":"Dullaart","year":"2009","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.arcmed.2018.07.002_bib35","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1159\/000336589","article-title":"Increased risk of unfavorable metabolic outcome during short-term follow-up in subjects with nonfunctioning adrenal adenomas","volume":"21","author":"Yener","year":"2012","journal-title":"Med Princ Pract"},{"key":"10.1016\/j.arcmed.2018.07.002_bib36","doi-asserted-by":"crossref","first-page":"2877","DOI":"10.1016\/S0024-3205(03)00195-4","article-title":"Serum paraoxonase activity decreases in rheumatoid arthritis","volume":"72","author":"Tanimoto","year":"2003","journal-title":"Life Sci"},{"key":"10.1016\/j.arcmed.2018.07.002_bib37","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/eci.12610","article-title":"Association of serum amyloid A and oxidative stress with paraoxonase 1 in sarcoidosis patients","volume":"46","author":"Ivani\u0161evi\u0107","year":"2016","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.arcmed.2018.07.002_bib38","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1080\/07435809609043773","article-title":"Adrenal incidentalomas: a manifestation of the metabolic syndrome?","volume":"22","author":"Reincke","year":"1996","journal-title":"Endocr Res"},{"key":"10.1016\/j.arcmed.2018.07.002_bib39","doi-asserted-by":"crossref","first-page":"662","DOI":"10.4158\/EP161713.OR","article-title":"Pentraxin 3 as a new cardiovascular marker in adrenal adenomas","volume":"23","author":"Kizilgul","year":"2017","journal-title":"Endocr Pract"},{"key":"10.1016\/j.arcmed.2018.07.002_bib40","doi-asserted-by":"crossref","first-page":"3117","DOI":"10.1194\/jlr.M005413","article-title":"Impact of serum amyloid A on high density lipoprotein composition and levels","volume":"51","author":"De Beer","year":"2010","journal-title":"J Lipid Res"},{"key":"10.1016\/j.arcmed.2018.07.002_bib41","first-page":"786","article-title":"Low DHEAS: A Sensitive and Specific Test for the Detection of Subclinical Hypercortisolism in Adrenal Incidentalomas","volume":"102","author":"Dennedy","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.arcmed.2018.07.002_bib42","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1210\/jc.2009-2387","article-title":"Beneficial metabolic effects of prompt surgical treatment in patients with an adrenal incidentaloma causing biochemical hypercortisolism","volume":"95","author":"Chiodini","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.arcmed.2018.07.002_bib43","doi-asserted-by":"crossref","first-page":"R283","DOI":"10.1530\/EJE-16-0465","article-title":"Improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and subclinical Cushing's syndrome: a systematic review and meta-analysis","volume":"175","author":"Bancos","year":"2016","journal-title":"Eur J Endocrinol"}],"container-title":["Archives of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440918303722?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440918303722?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T19:46:42Z","timestamp":1759261602000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0188440918303722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S0188440918303722"],"URL":"https:\/\/doi.org\/10.1016\/j.arcmed.2018.07.002","relation":{},"ISSN":["0188-4409"],"issn-type":[{"value":"0188-4409","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serum Amyloid A, Paraoxonase-1 Activity, and Apolipoprotein Concentrations as Biomarkers of Subclinical Atherosclerosis Risk in Adrenal Incidentaloma Patients","name":"articletitle","label":"Article Title"},{"value":"Archives of Medical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arcmed.2018.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 IMSS. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}