{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:51:22Z","timestamp":1791579082033,"version":"4.3.4"},"reference-count":134,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["JP25K03026"],"award-info":[{"award-number":["JP25K03026"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["24K20661"],"award-info":[{"award-number":["24K20661"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Medical Research"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.arcmed.2026.103529","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:17:16Z","timestamp":1791469036000},"page":"103529","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early-Life Nutritional and Environmental Factors in the Pathogenesis of Metabolic Dysfunction\u2013Associated Steatotic Liver Disease: A DOHaD Perspective"],"prefix":"10.1016","volume":"58","author":[{"given":"Adachi","family":"Haruka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiori","family":"Ishiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7929-4667","authenticated-orcid":false,"given":"Kazuki","family":"Mochizuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arcmed.2026.103529_bib0001","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.cgh.2025.06.011","article-title":"Optimal Cutoffs of Fatty Liver Index and Hepatic Steatosis Index in Diagnosing Pediatric Metabolic Dysfunction-associated Steatotic Liver Disease","volume":"24","author":"Song","year":"2026","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0002","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/apt.70174","article-title":"Anthropometric Measures and Mortality Risk in Individuals With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Population-Based Cohort Study","volume":"62","author":"Yeo","year":"2025","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.arcmed.2026.103529_bib0003","doi-asserted-by":"crossref","first-page":"3041","DOI":"10.2147\/DMSO.S523139","article-title":"Atherogenic Combined Index is Independently Associated with MASLD in Type 2 Diabetes: A Cross-Sectional Study","volume":"18","author":"Sheng","year":"2025","journal-title":"Diabetes Metab Syndr Obes"},{"key":"10.1016\/j.arcmed.2026.103529_bib0004","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1152\/japplphysiol.00040.2022","article-title":"Effects of metabolic syndrome on fuel utilization during exercise in middle-aged moderately trained individuals","volume":"132","author":"Alvarez-Jimenez","year":"2022","journal-title":"J Appl Physiol (1985)"},{"key":"10.1016\/j.arcmed.2026.103529_bib0005","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/ng.120","article-title":"Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes","volume":"40","author":"Zeggini","year":"2008","journal-title":"Nat Genet"},{"key":"10.1016\/j.arcmed.2026.103529_bib0006","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/s00125-012-2715-x","article-title":"The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study","volume":"56","author":"InterAct","year":"2013","journal-title":"Diabetologia"},{"key":"10.1016\/j.arcmed.2026.103529_bib0007","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1136\/heart.84.6.595","article-title":"Coronary heart disease after prenatal exposure to the Dutch famine, 1944-45","volume":"84","author":"Roseboom","year":"2000","journal-title":"Heart"},{"key":"10.1016\/j.arcmed.2026.103529_bib0008","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1093\/ajcn\/84.2.322","article-title":"Early onset of coronary artery disease after prenatal exposure to the Dutch famine","volume":"84","author":"Painter","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.arcmed.2026.103529_bib0009","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1007\/s10654-006-9065-2","article-title":"Exposure to famine during gestation, size at birth, and blood pressure at age 59 y: evidence from the Dutch Famine","volume":"21","author":"Stein","year":"2006","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0010","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.2337\/dc06-0460","article-title":"Impaired insulin secretion after prenatal exposure to the Dutch famine","volume":"29","author":"de Rooij","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1016\/j.arcmed.2026.103529_bib0011","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1056\/NEJM197608122950701","article-title":"Obesity in young men after famine exposure in utero and early infancy","volume":"295","author":"Ravelli","year":"1976","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arcmed.2026.103529_bib0012","doi-asserted-by":"crossref","first-page":"5R","DOI":"10.1203\/pdr.0b013e318045bedb","article-title":"Epigenetic mechanisms and the mismatch concept of the developmental origins of health and disease","volume":"61","author":"Godfrey","year":"2007","journal-title":"Pediatr Res"},{"key":"10.1016\/j.arcmed.2026.103529_bib0013","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1365-2796.2007.01802.x","article-title":"Developmental plasticity and human disease: research directions","volume":"261","author":"Gluckman","year":"2007","journal-title":"J Intern Med"},{"key":"10.1016\/j.arcmed.2026.103529_bib0014","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1126\/science.1095292","article-title":"Living with the past: evolution, development, and patterns of disease","volume":"305","author":"Gluckman","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.arcmed.2026.103529_bib0015","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1017\/S2040174409990171","article-title":"A conceptual framework for the developmental origins of health and disease","volume":"1","author":"Gluckman","year":"2010","journal-title":"J Dev Orig Health Dis"},{"key":"10.1016\/j.arcmed.2026.103529_bib0016","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/1747-0080.12617","article-title":"The first 1000 days: A critical period of nutritional opportunity and vulnerability","volume":"77","author":"Scott","year":"2020","journal-title":"Nutr Diet"},{"key":"10.1016\/j.arcmed.2026.103529_bib0017","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1136\/adc.87.6.478","article-title":"Breast feeding and allergic diseases in infants-a prospective birth cohort study","volume":"87","author":"Kull","year":"2002","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.arcmed.2026.103529_bib0018","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1111\/dom.13230","article-title":"Antibiotic exposure in early life and childhood overweight and obesity: A systematic review and meta-analysis","volume":"20","author":"Rasmussen","year":"2018","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.arcmed.2026.103529_bib0019","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1186\/s12889-021-10297-8","article-title":"Effectiveness and process evaluation in obesity and type 2 diabetes prevention programs in children: a systematic review and meta-analysis","volume":"21","author":"Seral-Cortes","year":"2021","journal-title":"BMC Public Health"},{"key":"10.1016\/j.arcmed.2026.103529_bib0020","doi-asserted-by":"crossref","first-page":"13705","DOI":"10.1073\/pnas.1110105108","article-title":"Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals","volume":"108","author":"Rabol","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.arcmed.2026.103529_bib0021","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1152\/physrev.00029.2013","article-title":"Early developmental conditioning of later health and disease: physiology or pathophysiology?","volume":"94","author":"Hanson","year":"2014","journal-title":"Physiol Rev"},{"key":"10.1016\/j.arcmed.2026.103529_bib0022","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.jhep.2021.06.045","article-title":"Maternal obesity increases the risk and severity of NAFLD in offspring","volume":"75","author":"Hagstrom","year":"2021","journal-title":"J Hepatol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0023","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1161\/CIRCULATIONAHA.111.070060","article-title":"Associations of maternal prepregnancy body mass index and gestational weight gain with adult offspring cardiometabolic risk factors: the Jerusalem Perinatal Family Follow-up Study","volume":"125","author":"Hochner","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.arcmed.2026.103529_bib0024","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.tjnut.2023.01.039","article-title":"Maternal Diet Quality During Pregnancy and Offspring Hepatic Fat in Early Childhood: The Healthy Start Study","volume":"153","author":"Cohen","year":"2023","journal-title":"J Nutr"},{"key":"10.1016\/j.arcmed.2026.103529_bib0025","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1038\/ajg.2017.140","article-title":"Low Birthweight Increases the Likelihood of Severe Steatosis in Pediatric Non-Alcoholic Fatty Liver Disease","volume":"112","author":"Bugianesi","year":"2017","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0026","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s12887-016-0585-y","article-title":"Association of maternal diabetes\/glycosuria and pre-pregnancy body mass index with offspring indicators of non-alcoholic fatty liver disease","volume":"16","author":"Patel","year":"2016","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.arcmed.2026.103529_bib0027","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.jhep.2017.03.029","article-title":"Infant nutrition and maternal obesity influence the risk of non-alcoholic fatty liver disease in adolescents","volume":"67","author":"Ayonrinde","year":"2017","journal-title":"J Hepatol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0028","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/aje\/kwi222","article-title":"Duration of breastfeeding and risk of overweight: a meta-analysis","volume":"162","author":"Harder","year":"2005","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0029","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.nutres.2016.03.003","article-title":"Introduction of complementary feeding before 4months of age increases the risk of childhood overweight or obesity: a meta-analysis of prospective cohort studies","volume":"36","author":"Wang","year":"2016","journal-title":"Nutr Res"},{"key":"10.1016\/j.arcmed.2026.103529_bib0030","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.jhep.2014.04.018","article-title":"Weight trajectories through infancy and childhood and risk of non-alcoholic fatty liver disease in adolescence: the ALSPAC study","volume":"61","author":"Anderson","year":"2014","journal-title":"J Hepatol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0031","first-page":"607","article-title":"Early adiposity rebound: review of papers linking this to subsequent obesity in children and adults","volume":"8","author":"Taylor","year":"2005","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.arcmed.2026.103529_bib0032","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/oby.2008.547","article-title":"Patterns of growth associated with the timing of adiposity rebound","volume":"17","author":"Williams","year":"2009","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.arcmed.2026.103529_bib0033","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.3945\/ajcn.2008.27038","article-title":"Lipid profiles in middle-aged men and women after famine exposure during gestation: the Dutch Hunger Winter Families Study","volume":"89","author":"Lumey","year":"2009","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.arcmed.2026.103529_bib0034","doi-asserted-by":"crossref","first-page":"16757","DOI":"10.1073\/pnas.1012911107","article-title":"The Dutch Hunger Winter and the developmental origins of health and disease","volume":"107","author":"Schulz","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.arcmed.2026.103529_bib0035","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/ppe.13131","article-title":"Women exposed to famine in early gestation have increased mortality up to age 76 years","volume":"39","author":"Wiegersma","year":"2025","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0036","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0026-0495(82)90056-7","article-title":"Fatty acid synthesis in rat fetuses with intrauterine growth retardation","volume":"31","author":"Vileisis","year":"1982","journal-title":"Metabolism"},{"key":"10.1016\/j.arcmed.2026.103529_bib0037","doi-asserted-by":"crossref","first-page":"4955","DOI":"10.1210\/en.2012-1349","article-title":"Hepatic insulin signaling changes: possible mechanism in prenatal hypoxia-increased susceptibility of fatty liver in adulthood","volume":"153","author":"Cao","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.arcmed.2026.103529_bib0038","doi-asserted-by":"crossref","DOI":"10.1038\/srep16867","article-title":"Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet;Involvement of Endoplasmic Reticulum Stress","volume":"5","author":"Muramatsu-Kato","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.arcmed.2026.103529_bib0039","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/cga.12200","article-title":"Undernourishment in utero and hepatic steatosis in later life: A potential issue in Japanese people","volume":"57","author":"Itoh","year":"2017","journal-title":"Congenit Anom (Kyoto)"},{"key":"10.1016\/j.arcmed.2026.103529_bib0040","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s13105-017-0549-1","article-title":"Protein malnutrition during fetal programming induces fatty liver in adult male offspring rats","volume":"73","author":"Campisano","year":"2017","journal-title":"J Physiol Biochem"},{"key":"10.1016\/j.arcmed.2026.103529_bib0041","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.aanat.2012.05.006","article-title":"Effect of maternal low protein diet during pregnancy on the fetal liver of rats","volume":"195","author":"Ramadan","year":"2013","journal-title":"Ann Anat"},{"key":"10.1016\/j.arcmed.2026.103529_bib0042","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.reprotox.2016.08.006","article-title":"Increased susceptibility of prenatal food restricted offspring to high-fat diet-induced nonalcoholic fatty liver disease is intrauterine programmed","volume":"65","author":"Zhang","year":"2016","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0043","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/apha.12197","article-title":"Maternal western diet primes non-alcoholic fatty liver disease in adult mouse offspring","volume":"210","author":"Pruis","year":"2014","journal-title":"Acta Physiol (Oxf)"},{"key":"10.1016\/j.arcmed.2026.103529_bib0044","article-title":"Consumption of barley ameliorates the diabetic steatohepatitis and reduces the high transforming growth factor beta expression in mice grown in alpha-minimum essential medium in vitro as embryos","volume":"27","author":"Ishiyama","year":"2021","journal-title":"Biochem Biophys Rep"},{"key":"10.1016\/j.arcmed.2026.103529_bib0045","first-page":"1166","article-title":"Maternal Obesity Programs the Premature Aging of Rat Offspring Liver Mitochondrial Electron Transport Chain Genes in a Sex-Dependent Manner","volume":"12","author":"Lomas-Soria","year":"2023","journal-title":"Biology (Basel)"},{"key":"10.1016\/j.arcmed.2026.103529_bib0046","doi-asserted-by":"crossref","first-page":"5549","DOI":"10.1113\/JP278232","article-title":"Maternal obesity accelerates rat offspring metabolic ageing in a sex-dependent manner","volume":"597","author":"Rodriguez-Gonzalez","year":"2019","journal-title":"J Physiol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0047","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0076705","article-title":"Effects on transcriptional regulation and lipid droplet characteristics in the liver of female juvenile pigs after early postnatal feed restriction and refeeding are dependent on birth weight","volume":"8","author":"Nebendahl","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.arcmed.2026.103529_bib0048","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.theriogenology.2024.06.020","article-title":"Transcriptome analysis reveals hepatic disordered lipid metabolism, lipotoxic injury, and abnormal development in IUGR sheep fetuses due to maternal undernutrition during late pregnancy","volume":"226","author":"Zi","year":"2024","journal-title":"Theriogenology"},{"key":"10.1016\/j.arcmed.2026.103529_bib0049","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.3390\/nu14102045","article-title":"Litter Size Reduction as a Model of Overfeeding during Lactation and Its Consequences for the Development of Metabolic Diseases in the Offspring","volume":"14","author":"Souza","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.arcmed.2026.103529_bib0050","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jhep.2015.08.022","article-title":"Gestational exercise protects adult male offspring from high-fat diet-induced hepatic steatosis","volume":"64","author":"Sheldon","year":"2016","journal-title":"J Hepatol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0051","doi-asserted-by":"crossref","first-page":"4726","DOI":"10.3390\/nu15224726","article-title":"Maternal Folic Acid Supplementation during Pregnancy Prevents Hepatic Steatosis in Male Offspring of Rat Dams Fed High-Fat Diet, Which Is Associated with the Regulation of Gut Microbiota","volume":"15","author":"Zhang","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.arcmed.2026.103529_bib0052","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.3390\/nu13093075","article-title":"Maternal DHA Supplementation during Pregnancy and Lactation in the Rat Protects the Offspring against High-Calorie Diet-Induced Hepatic Steatosis","volume":"13","author":"Daher-Abdi","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.arcmed.2026.103529_bib0053","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2025.112484","article-title":"Maternal protein restriction and postnatal sugar consumption increases inflammatory response and deregulates metabolic pathways in the liver of male offspring rats with aging","volume":"599","author":"Ribeiro","year":"2025","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0054","doi-asserted-by":"crossref","DOI":"10.1152\/ajpendo.00184.2025","article-title":"Early complete weaning in mice induces hepatic steatosis, which is associated with changes in phospholipids, metabolites, gene expression, and epigenome","volume":"329","author":"Adachi","year":"2025","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.arcmed.2026.103529_bib0055","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1017\/S0007114510005064","article-title":"Early weaning causes undernutrition for a short period and programmes some metabolic syndrome components and leptin resistance in adult rat offspring","volume":"105","author":"Lima Nda","year":"2011","journal-title":"Br J Nutr"},{"key":"10.1016\/j.arcmed.2026.103529_bib0056","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.jnutbio.2012.06.019","article-title":"Resveratrol attenuates oxidative stress and prevents steatosis and hypertension in obese rats programmed by early weaning","volume":"24","author":"Franco","year":"2013","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.arcmed.2026.103529_bib0057","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1017\/S2040174423000272","article-title":"Puberty as a DOHaD programming window: high-fat diet induces long-term hepatic dysfunction in male rats","volume":"14","author":"Dos Santos","year":"2023","journal-title":"J Dev Orig Health Dis"},{"key":"10.1016\/j.arcmed.2026.103529_bib0058","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1017\/S2040174420000598","article-title":"Post-weaning exposure to high-sucrose diet induces early non-alcoholic fatty liver disease onset and progression in male mice: role of dysfunctional white adipose tissue","volume":"11","author":"Franca","year":"2020","journal-title":"J Dev Orig Health Dis"},{"key":"10.1016\/j.arcmed.2026.103529_bib0059","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1186\/s12944-020-01425-1","article-title":"Hepatic lipid profile in mice fed a choline-deficient, low-methionine diet resembles human non-alcoholic fatty liver disease","volume":"19","author":"Haberl","year":"2020","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.arcmed.2026.103529_bib0060","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1038\/pr.2012.173","article-title":"Plasma lipid levels and body weight altered by intrauterine growth restriction and postnatal fructose diet in adult rats","volume":"73","author":"Malo","year":"2013","journal-title":"Pediatr Res"},{"key":"10.1016\/j.arcmed.2026.103529_bib0061","doi-asserted-by":"crossref","first-page":"190","DOI":"10.2527\/jas1985.601190x","article-title":"Effect of swine weaning age on body fat and lipogenic activity in liver and adipose tissue","volume":"60","author":"Fenton","year":"1985","journal-title":"J Anim Sci"},{"key":"10.1016\/j.arcmed.2026.103529_bib0062","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1113\/jphysiol.2005.100313","article-title":"A low maternal protein diet during pregnancy and lactation has sex- and window of exposure-specific effects on offspring growth and food intake, glucose metabolism and serum leptin in the rat","volume":"571","author":"Zambrano","year":"2006","journal-title":"J Physiol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0063","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13293-021-00365-4","article-title":"Sex-dependent effects of prenatal food and protein restriction on offspring physiology in rats and mice: systematic review and meta-analyses","volume":"12","author":"Christians","year":"2021","journal-title":"Biol Sex Differ"},{"key":"10.1016\/j.arcmed.2026.103529_bib0064","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0046057","article-title":"Female mice are protected against high-fat diet induced metabolic syndrome and increase the regulatory T cell population in adipose tissue","volume":"7","author":"Pettersson","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.arcmed.2026.103529_bib0065","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0092-8674(00)81294-5","article-title":"Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db\/db mice","volume":"84","author":"Chen","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.arcmed.2026.103529_bib0066","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1210\/endo.142.1.7909","article-title":"Transgenic mice overexpressing leptin accumulate adipose mass at an older, but not younger, age","volume":"142","author":"Qiu","year":"2001","journal-title":"Endocrinology"},{"key":"10.1016\/j.arcmed.2026.103529_bib0067","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/JCMA.0000000000000507","article-title":"Association of insulin resistance and leptin receptor gene polymorphism in type 2 diabetes mellitus","volume":"84","author":"Adiga","year":"2021","journal-title":"J Chin Med Assoc"},{"key":"10.1016\/j.arcmed.2026.103529_bib0068","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1507\/endocrj.K06-225","article-title":"The relationship between maternal plasma leptin levels and fetal growth restriction","volume":"54","author":"Mise","year":"2007","journal-title":"Endocr J"},{"key":"10.1016\/j.arcmed.2026.103529_bib0069","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000296","article-title":"Maternal obesity-induced endoplasmic reticulum stress causes metabolic alterations and abnormal hypothalamic development in the offspring","volume":"18","author":"Park","year":"2020","journal-title":"PLoS Biol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0070","doi-asserted-by":"crossref","DOI":"10.1111\/ijpo.12955","article-title":"Cord blood leptin level and a common variant of its receptor as determinants of the BMI trajectory: The EDEN mother-child cohort","volume":"17","author":"Cisse","year":"2022","journal-title":"Pediatr Obes"},{"key":"10.1016\/j.arcmed.2026.103529_bib0071","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.2337\/diabetes.50.10.2279","article-title":"Intrauterine growth retardation leads to the development of type 2 diabetes in the rat","volume":"50","author":"Simmons","year":"2001","journal-title":"Diabetes"},{"key":"10.1016\/j.arcmed.2026.103529_bib0072","doi-asserted-by":"crossref","first-page":"4782","DOI":"10.1210\/en.2016-1167","article-title":"Maternal Low Protein Isocaloric Diet Suppresses Pancreatic beta-Cell Proliferation in Mouse Offspring via miR-15b","volume":"157","author":"Su","year":"2016","journal-title":"Endocrinology"},{"key":"10.1016\/j.arcmed.2026.103529_bib0073","doi-asserted-by":"crossref","first-page":"4395","DOI":"10.1172\/JCI74237","article-title":"Maternal diet-induced microRNAs and mTOR underlie beta cell dysfunction in offspring","volume":"124","author":"Alejandro","year":"2014","journal-title":"J Clin Invest"},{"key":"10.1016\/j.arcmed.2026.103529_bib0074","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2020.e03597","article-title":"Excessive folic acid supplementation in pregnant mice impairs insulin secretion and induces the expression of genes associated with fatty liver in their offspring","volume":"6","author":"Kintaka","year":"2020","journal-title":"Heliyon"},{"key":"10.1016\/j.arcmed.2026.103529_bib0075","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s00467-009-1407-3","article-title":"Fetal growth restriction, catch-up growth and the early origins of insulin resistance and visceral obesity","volume":"25","author":"Morrison","year":"2010","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0076","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2025.123384","article-title":"The multifaceted function of FoxO1 in pancreatic beta-cell dysfunction and insulin resistance: Therapeutic potential for type 2 diabetes","volume":"364","author":"Wang","year":"2025","journal-title":"Life Sci"},{"key":"10.1016\/j.arcmed.2026.103529_bib0077","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0238223","article-title":"Elevated blood pressure in high-fat diet-exposed low birthweight rat offspring is most likely caused by elevated glucocorticoid levels due to abnormal pituitary negative feedback","volume":"15","author":"Nemoto","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.arcmed.2026.103529_bib0078","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s12020-019-02080-y","article-title":"Early weaning leads to specific glucocorticoid signalling in fat depots of adult rats","volume":"67","author":"Miranda","year":"2020","journal-title":"Endocrine"},{"key":"10.1016\/j.arcmed.2026.103529_bib0079","doi-asserted-by":"crossref","DOI":"10.1530\/JME-25-0056","article-title":"Chronic stress-secreted glucocorticoids induce NAFLD-like changes in male rats: oxidative stress\/NLRP3 inflammasome signalling","volume":"75","author":"Shao","year":"2025","journal-title":"J Mol Endocrinol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0080","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1203\/PDR.0b013e3181a2047e","article-title":"Intrauterine growth restriction alters postnatal colonic barrier maturation in rats","volume":"66","author":"Fanca-Berthon","year":"2009","journal-title":"Pediatr Res"},{"key":"10.1016\/j.arcmed.2026.103529_bib0081","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2022.111605","article-title":"Protein restriction during the fetal period upregulates IL1B and IL13 while suppressing Muc2 expression in the jejunum of mice after weaning","volume":"98","author":"Adachi","year":"2022","journal-title":"Nutrition"},{"key":"10.1016\/j.arcmed.2026.103529_bib0082","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/bph.14095","article-title":"Tauroursodeoxycholic acid inhibits intestinal inflammation and barrier disruption in mice with non-alcoholic fatty liver disease","volume":"175","author":"Wang","year":"2018","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0083","article-title":"Dietary protein restriction during pregnancy and\/or early weaning reduces the number of goblet cells in the small and large intestines of female mice pups","volume":"34","author":"Adachi","year":"2023","journal-title":"Biochem Biophys Rep"},{"key":"10.1016\/j.arcmed.2026.103529_bib0084","doi-asserted-by":"crossref","first-page":"G352","DOI":"10.1152\/ajpgi.00081.2009","article-title":"Early weaning stress impairs development of mucosal barrier function in the porcine intestine","volume":"298","author":"Smith","year":"2010","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0085","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0290532","article-title":"Lobeglitazone inhibits LPS-induced NLRP3 inflammasome activation and inflammation in the liver","volume":"18","author":"Seo","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.arcmed.2026.103529_bib0086","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1084\/jem.20061884","article-title":"Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement","volume":"203","author":"Chieppa","year":"2006","journal-title":"J Exp Med"},{"key":"10.1016\/j.arcmed.2026.103529_bib0087","doi-asserted-by":"crossref","first-page":"3101","DOI":"10.1084\/jem.20091925","article-title":"Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions","volume":"206","author":"Schulz","year":"2009","journal-title":"J Exp Med"},{"key":"10.1016\/j.arcmed.2026.103529_bib0088","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1053\/j.gastro.2013.01.023","article-title":"The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice","volume":"144","author":"Cao","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.arcmed.2026.103529_bib0089","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-52943-7","article-title":"Plasticity of histone modifications around Cidea and Cidec genes with secondary bile in the amelioration of developmentally-programmed hepatic steatosis","volume":"9","author":"Urmi","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.arcmed.2026.103529_bib0090","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.5713\/ajas.18.0962","article-title":"Effects of dietary yeast beta-1,3-1,6-glucan on growth performance, intestinal morphology and chosen immunity parameters changes in Haidong chicks","volume":"32","author":"Ding","year":"2019","journal-title":"Asian-Australas J Anim Sci"},{"key":"10.1016\/j.arcmed.2026.103529_bib0091","first-page":"129","article-title":"High Molecular Weight Barley beta-Glucan Alters Gut Microbiota Toward Reduced Cardiovascular Disease Risk","volume":"7","author":"Wang","year":"2016","journal-title":"Front Microbiol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0092","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.2337\/db07-1403","article-title":"Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice","volume":"57","author":"Cani","year":"2008","journal-title":"Diabetes"},{"key":"10.1016\/j.arcmed.2026.103529_bib0093","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s11154-019-09512-0","article-title":"Dietary lipids, gut microbiota and lipid metabolism","volume":"20","author":"Schoeler","year":"2019","journal-title":"Rev Endocr Metab Disord"},{"key":"10.1016\/j.arcmed.2026.103529_bib0094","doi-asserted-by":"crossref","first-page":"662","DOI":"10.3390\/ijms23020662","article-title":"The Intestinal Barrier and Its Dysfunction in Patients with Metabolic Diseases and Non-Alcoholic Fatty Liver Disease","volume":"23","author":"Forlano","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.arcmed.2026.103529_bib0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/j.2040-4603.2018.tb00008.x","article-title":"Triglyceride Metabolism in the Liver","volume":"8","author":"Alves-Bezerra","year":"2017","journal-title":"Compr Physiol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0096","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12263-016-0541-3","article-title":"The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport","volume":"11","author":"Daniel","year":"2016","journal-title":"Genes Nutr"},{"key":"10.1016\/j.arcmed.2026.103529_bib0097","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1161\/01.ATV.19.3.472","article-title":"Role of ApoCs in lipoprotein metabolism: functional differences between ApoC1, ApoC2, and ApoC3","volume":"19","author":"Jong","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0098","first-page":"2347","article-title":"FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice","volume":"118","author":"Kamagate","year":"2008","journal-title":"J Clin Invest"},{"key":"10.1016\/j.arcmed.2026.103529_bib0099","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1172\/JCI117151","article-title":"Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice","volume":"93","author":"Shachter","year":"1994","journal-title":"J Clin Invest"},{"key":"10.1016\/j.arcmed.2026.103529_bib0100","doi-asserted-by":"crossref","first-page":"3031","DOI":"10.1096\/fasebj.5.15.1743436","article-title":"New insights into the metabolic regulation of insulin action and insulin resistance: role of glucose and amino acids","volume":"5","author":"Marshall","year":"1991","journal-title":"FASEB J"},{"key":"10.1016\/j.arcmed.2026.103529_bib0101","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.genm.2012.01.004","article-title":"Sex-dependent programming of glucose and fatty acid metabolism in mouse offspring by maternal protein restriction","volume":"9","author":"van Straten","year":"2012","journal-title":"Gend Med"},{"key":"10.1016\/j.arcmed.2026.103529_bib0102","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/nature05482","article-title":"Mechanisms linking obesity to insulin resistance and type 2 diabetes","volume":"444","author":"Kahn","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.arcmed.2026.103529_bib0103","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1203\/PDR.0b013e31818702a2","article-title":"Maternal and fetal fatty acid profile in normal and intrauterine growth restriction pregnancies with and without preeclampsia","volume":"64","author":"Alvino","year":"2008","journal-title":"Pediatr Res"},{"key":"10.1016\/j.arcmed.2026.103529_bib0104","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s00125-017-4534-6","article-title":"Association of NEFA composition with insulin sensitivity and beta cell function in the Prospective Metabolism and Islet Cell Evaluation (PROMISE) cohort","volume":"61","author":"Johnston","year":"2018","journal-title":"Diabetologia"},{"key":"10.1016\/j.arcmed.2026.103529_bib0105","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1083\/jcb.200711136","article-title":"Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast","volume":"180","author":"Fei","year":"2008","journal-title":"J Cell Biol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0106","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1161\/ATVBAHA.111.241489","article-title":"CIDE proteins and lipid metabolism","volume":"32","author":"Xu","year":"2012","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0107","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1080\/15548627.2015.1124226","article-title":"AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA","volume":"12","author":"Kaushik","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.arcmed.2026.103529_bib0108","doi-asserted-by":"crossref","first-page":"4282","DOI":"10.1074\/jbc.M115.701094","article-title":"Differential Roles of Cell Death-inducing DNA Fragmentation Factor-alpha-like Effector (CIDE) Proteins in Promoting Lipid Droplet Fusion and Growth in Subpopulations of Hepatocytes","volume":"291","author":"Xu","year":"2016","journal-title":"J Biol Chem"},{"key":"10.1016\/j.arcmed.2026.103529_bib0109","doi-asserted-by":"crossref","first-page":"318","DOI":"10.3177\/jnsv.70.318","article-title":"Induction of the Lipid Droplet Formation Genes in Steatohepatitis Mice by Embryo\/Postnatal Nutrient Environment Is Associated with Histone Acetylation around the Genes","volume":"70","author":"Ishiyama","year":"2024","journal-title":"J Nutr Sci Vitaminol (Tokyo)"},{"key":"10.1016\/j.arcmed.2026.103529_bib0110","doi-asserted-by":"crossref","first-page":"9990","DOI":"10.1096\/fj.201900406R","article-title":"Maternal undernutrition induces fetal hepatic lipid metabolism disorder and affects the development of fetal liver in a sheep model","volume":"33","author":"Xue","year":"2019","journal-title":"FASEB J"},{"key":"10.1016\/j.arcmed.2026.103529_bib0111","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/apha.12211","article-title":"Pre-natal undernutrition and post-natal overnutrition are associated with permanent changes in hepatic metabolism markers and fatty acid composition in sheep","volume":"210","author":"Hou","year":"2014","journal-title":"Acta Physiol (Oxf)"},{"key":"10.1016\/j.arcmed.2026.103529_bib0112","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.cmet.2011.07.013","article-title":"Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase","volume":"14","author":"Krahmer","year":"2011","journal-title":"Cell Metab"},{"key":"10.1016\/j.arcmed.2026.103529_bib0113","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1530\/REP-19-0188","article-title":"Perinatal protein restriction with postnatal catch-up growth leads to elevated p66Shc and mitochondrial dysfunction in the adult rat liver","volume":"159","author":"Oke","year":"2020","journal-title":"Reproduction"},{"key":"10.1016\/j.arcmed.2026.103529_bib0114","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1111\/gtc.12098","article-title":"Metabolomics reveals that carnitine palmitoyltransferase-1 is a novel target for oxidative inactivation in human cells","volume":"18","author":"Setoyama","year":"2013","journal-title":"Genes Cells"},{"key":"10.1016\/j.arcmed.2026.103529_bib0115","doi-asserted-by":"crossref","first-page":"R183","DOI":"10.1152\/ajpregu.2001.280.1.R183","article-title":"Uteroplacental insufficiency alters hepatic fatty acid-metabolizing enzymes in juvenile and adult rats","volume":"280","author":"Lane","year":"2001","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0116","doi-asserted-by":"crossref","first-page":"9812","DOI":"10.1038\/s41598-017-10380-4","article-title":"Early gestational maternal low-protein diet diminishes hepatic response to fasting in young adult male mice","volume":"7","author":"Sato","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.arcmed.2026.103529_bib0117","doi-asserted-by":"crossref","DOI":"10.1152\/ajpendo.00600.2014","article-title":"Impact of maternal undernutrition around the time of conception on factors regulating hepatic lipid metabolism and microRNAs in singleton and twin fetuses","volume":"310","author":"Lie","year":"2016","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.arcmed.2026.103529_bib0118","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3389\/fgene.2018.00291","article-title":"Transcriptome Analyses Reveal Adult Metabolic Syndrome With Intrauterine Growth Restriction in Pig Models","volume":"9","author":"Shen","year":"2018","journal-title":"Front Genet"},{"issue":"Suppl","key":"10.1016\/j.arcmed.2026.103529_bib0119","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/ng1089","article-title":"Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals","volume":"33","author":"Jaenisch","year":"2003","journal-title":"Nat Genet"},{"key":"10.1016\/j.arcmed.2026.103529_bib0120","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/nature01080","article-title":"Active genes are tri-methylated at K4 of histone H3","volume":"419","author":"Santos-Rosa","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.arcmed.2026.103529_bib0121","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/nrg3173","article-title":"Histone methylation: a dynamic mark in health, disease and inheritance","volume":"13","author":"Greer","year":"2012","journal-title":"Nat Rev Genet"},{"key":"10.1016\/j.arcmed.2026.103529_bib0122","doi-asserted-by":"crossref","first-page":"12648","DOI":"10.1093\/nar\/gkaa1050","article-title":"Quantification of the effect of site-specific histone acetylation on chromatin transcription rate","volume":"48","author":"Wakamori","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.arcmed.2026.103529_bib0123","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1038\/nsmb.2370","article-title":"Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36","volume":"19","author":"Butler","year":"2012","journal-title":"Nat Struct Mol Biol"},{"key":"10.1016\/j.arcmed.2026.103529_bib0124","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3390\/jpm12020157","article-title":"Perinatal Origins of Adult Disease and Opportunities for Health Promotion: A Narrative Review","volume":"12","author":"Nobile","year":"2022","journal-title":"J Pers Med"},{"key":"10.1016\/j.arcmed.2026.103529_bib0125","doi-asserted-by":"crossref","first-page":"13611","DOI":"10.1074\/jbc.M800128200","article-title":"Histone code modifications repress glucose transporter 4 expression in the intrauterine growth-restricted offspring","volume":"283","author":"Raychaudhuri","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1016\/j.arcmed.2026.103529_bib0126","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1093\/jn\/135.6.1382","article-title":"Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring","volume":"135","author":"Lillycrop","year":"2005","journal-title":"J Nutr"},{"key":"10.1016\/j.arcmed.2026.103529_bib0127","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1017\/S000711450769196X","volume":"97","author":"Lillycrop","year":"2007","journal-title":"Br J Nutr"},{"key":"10.1016\/j.arcmed.2026.103529_bib0128","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2023.122315","article-title":"Impact of maternal fructose intake on liver stem\/progenitor cells in offspring: Insights into developmental origins of health and disease","volume":"336","author":"Ando","year":"2024","journal-title":"Life Sci"},{"key":"10.1016\/j.arcmed.2026.103529_bib0129","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112393","article-title":"Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring","volume":"42","author":"Nash","year":"2023","journal-title":"Cell Rep"},{"key":"10.1016\/j.arcmed.2026.103529_bib0130","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1111\/jpn.12933","article-title":"Methyl donors dietary supplementation to gestating sows diet improves the growth rate of offspring and is associating with changes in expression and DNA methylation of insulin-like growth factor-1 gene","volume":"102","author":"Jin","year":"2018","journal-title":"J Anim Physiol Anim Nutr (Berl)"},{"key":"10.1016\/j.arcmed.2026.103529_bib0131","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.bbalip.2015.10.002","article-title":"Gestational dietary betaine supplementation suppresses hepatic expression of lipogenic genes in neonatal piglets through epigenetic and glucocorticoid receptor-dependent mechanisms","volume":"1861","author":"Cai","year":"2016","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.arcmed.2026.103529_bib0132","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/cga.12213","article-title":"Relationship between epigenetic regulation, dietary habits, and the developmental origins of health and disease theory","volume":"57","author":"Mochizuki","year":"2017","journal-title":"Congenit Anom (Kyoto)"},{"key":"10.1016\/j.arcmed.2026.103529_bib0133","doi-asserted-by":"crossref","first-page":"775","DOI":"10.2337\/db14-0158","article-title":"Ligand-activated PPARalpha-dependent DNA demethylation regulates the fatty acid beta-oxidation genes in the postnatal liver","volume":"64","author":"Ehara","year":"2015","journal-title":"Diabetes"},{"key":"10.1016\/j.arcmed.2026.103529_bib0134","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.633564","article-title":"Weaning Induces Stress-Dependent DNA Methylation and Transcriptional Changes in Piglet PBMCs","volume":"12","author":"Corbett","year":"2021","journal-title":"Front Genet"}],"container-title":["Archives of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440926001517?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0188440926001517?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:24:44Z","timestamp":1791577484000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0188440926001517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":134,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2027,1]]}},"alternative-id":["S0188440926001517"],"URL":"https:\/\/doi.org\/10.1016\/j.arcmed.2026.103529","relation":{},"ISSN":["0188-4409"],"issn-type":[{"value":"0188-4409","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early-Life Nutritional and Environmental Factors in the Pathogenesis of Metabolic Dysfunction\u2013Associated Steatotic Liver Disease: A DOHaD Perspective","name":"articletitle","label":"Article Title"},{"value":"Archives of Medical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arcmed.2026.103529","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc. on behalf of Instituto Mexicano del Seguro Social (IMSS).","name":"copyright","label":"Copyright"}],"article-number":"103529"}}