{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T03:04:10Z","timestamp":1771556650708,"version":"3.50.1"},"reference-count":56,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives de P\u00e9diatrie"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.arcped.2019.05.010","type":"journal-article","created":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T01:06:36Z","timestamp":1562115996000},"page":"308-311","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Therapeutic hypothermia in children: Which indications remain in 2018?"],"prefix":"10.1016","volume":"26","author":[{"given":"F.","family":"Thabet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Tabarki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arcped.2019.05.010_bib0285","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1161\/STROKEAHA.108.521583","article-title":"Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis","volume":"39","author":"Greer","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.arcped.2019.05.010_bib0290","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1542\/peds.2007-1673","article-title":"Elevated temperature after hypoxic-ischemic encephalopathy: risk factor for adverse outcomes","volume":"122","author":"Laptook","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.arcped.2019.05.010_bib0295","doi-asserted-by":"crossref","first-page":"2608","DOI":"10.1097\/00003246-200007000-00071","article-title":"Early hyperthermia after traumatic brain injury in children: risk factors, influence on length of stay, and effect on short-term neurologic status","volume":"28","author":"Natale","year":"2000","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0300","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.cnc.2015.02.009","article-title":"Considerations for neuroprotection in the traumatic brain injury population","volume":"27","author":"Bergman","year":"2015","journal-title":"Crit Care Nurs Clin North Am"},{"key":"10.1016\/j.arcped.2019.05.010_bib0305","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1089\/neu.2008.0587","article-title":"Therapeutic hypothermia: applications in pediatric cardiac arrest","volume":"26","author":"Kochanek","year":"2009","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.arcped.2019.05.010_bib0310","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/nrn3174","article-title":"Neuroprotective mechanisms of hypothermia in brain ischaemia","volume":"13","author":"Yenari","year":"2012","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.arcped.2019.05.010_bib0315","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1159\/000085992","article-title":"Brief induced hypothermia improves outcome after asphyxial cardiopulmonary arrest in juvenile rats","volume":"27","author":"Fink","year":"2005","journal-title":"Dev Neuroscience"},{"key":"10.1016\/j.arcped.2019.05.010_bib0320","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1097\/MOP.0000000000000199","article-title":"Therapeutic hypothermia for neonatal encephalopathy","volume":"27","author":"Shankaran","year":"2015","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.arcped.2019.05.010_bib0325","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1016\/j.resuscitation.2017.07.007","article-title":"Feasibility of whole body hypothermia for neonates without congenital heart defects surviving in-hospital cardiac arrest unrelated to perinatal asphyxia","volume":"119","author":"Dell\u2019Orto","year":"2017","journal-title":"Resuscitation"},{"key":"10.1016\/j.arcped.2019.05.010_bib0330","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1164\/rccm.201602-0422LE","article-title":"IGLOO Study Group. Hypothermia and meconium aspiration syndrome: International Multicenter Retrospective Cohort Study","volume":"194","author":"De Luca","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0335","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0192295","article-title":"Controlled hypothermia may improve surfactant function in asphyxiated neonates with or without meconium aspiration syndrome","volume":"13","author":"Autilio","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.arcped.2019.05.010_bib0340","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/CCM.0b013e3181aa5d0c","article-title":"Hypothermia after cardiac arrest: expanding the therapeutic scope","volume":"37","author":"Bernard","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0345","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1097\/CCM.0000000000002205","article-title":"Meta-analysis of therapeutic hypothermia for traumatic brain injury in adult and pediatric patients","volume":"45","author":"Crompton","year":"2017","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0350","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1097\/CCM.0b013e3181962ad5","article-title":"Therapeutic hypothermia and controlled normothermia in the intensive care unit: practical considerations, side effects, and cooling methods","volume":"37","author":"Polderman","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0355","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1097\/CCM.0b013e318206bab2","article-title":"Targeted temperature management in critical care: a report and recommendations from five professional societies","volume":"39","author":"Nunnally","year":"2011","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0360","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1161\/CIRCULATIONAHA.109.848424","article-title":"Intra-cardiopulmonary resuscitation hypothermia with and without volume loading in an ischemic model of cardiac arrest","volume":"16","author":"Yannopoulos","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.arcped.2019.05.010_bib0365","doi-asserted-by":"crossref","first-page":"2786","DOI":"10.1161\/01.CIR.0000131940.19833.85","article-title":"Intra-arrest cooling improves outcomes in a murine cardiac arrest model","volume":"16","author":"Abella","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.arcped.2019.05.010_bib0370","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1056\/NEJMoa003289","article-title":"Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia","volume":"346","author":"Bernard","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0375","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1056\/NEJMoa012689","article-title":"Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest","volume":"346","author":"Group","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0380","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s13054-018-1984-2","article-title":"The efficacy and safety of pre-hospital cooling after out-of-hospital cardiac arrest: a systematic review and meta-analysis","volume":"22","author":"Lindsay","year":"2018","journal-title":"Crit Care"},{"key":"10.1016\/j.arcped.2019.05.010_bib0385","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1056\/NEJMoa1411480","article-title":"Therapeutic hypothermia after out-of-hospital cardiac arrest in children","volume":"372","author":"Moler","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0390","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1056\/NEJMoa1610493","article-title":"Therapeutic hypothermia after in-hospital cardiac arrest in children","volume":"376","author":"Moler","year":"2017","journal-title":"New Engl J Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0395","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.resuscitation.2018.02.022","article-title":"Post-arrest therapeutic hypothermia in pediatric patients with congenital heart disease","volume":"126","author":"Cheng","year":"2018","journal-title":"Resuscitation"},{"key":"10.1016\/j.arcped.2019.05.010_bib0400","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.resuscitation.2018.02.008","article-title":"24 vs. 72 hours of hypothermia for pediatric cardiac arrest: a pilot randomized controlled trial","volume":"126","author":"Fink","year":"2018","journal-title":"Resuscitation"},{"key":"10.1016\/j.arcped.2019.05.010_bib0405","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.nurt.2009.10.015","article-title":"The evidence for hypothermia as a neuroprotectant in traumatic brain injury","volume":"7","author":"Dietrich","year":"2010","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.arcped.2019.05.010_bib0410","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/jcbfm.1991.13","article-title":"Marked protection by moderate hypothermia after experimental traumatic brain injury","volume":"11","author":"Clifton","year":"1991","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.arcped.2019.05.010_bib0415","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/00004647-199603000-00010","article-title":"Mild posttraumatic hypothermia reduces mortality after severe controlled cortical impact in rats","volume":"16","author":"Clark","year":"1996","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.arcped.2019.05.010_bib0420","article-title":"Hypothermia for traumatic brain injury","volume":"9","author":"Lewis","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.arcped.2019.05.010_bib0425","doi-asserted-by":"crossref","first-page":"2992","DOI":"10.1001\/jama.289.22.2992","article-title":"Prolonged therapeutic hypothermia after traumatic brain injury in adults: a systematic review","volume":"289","author":"McIntyre","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.arcped.2019.05.010_bib0430","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1097\/CCM.0000000000003125","article-title":"Revisited: a systematic review of therapeutic hypothermia for adult patient following traumatic brain injury","volume":"46","author":"Watson","year":"2018","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.arcped.2019.05.010_bib0435","first-page":"1","article-title":"Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents-second edition","volume":"13","author":"Kochanek","year":"2012","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0440","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1097\/CCM.0000000000000947","article-title":"Pediatric Study Group of the Australia and New Zealand Intensive Care Society Clinical Trials Group: hypothermia for traumatic brain injury in children-A phase II randomized controlled trial","volume":"43","author":"Beca","year":"2015","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0445","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/S1474-4422(13)70077-2","article-title":"Paediatric traumatic brain injury consortium: comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomized controlled trial","volume":"12","author":"Adelson","year":"2013","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.arcped.2019.05.010_bib0450","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/bja\/aes500","article-title":"Role of therapeutic hypothermia in improving outcome after traumatic brain injury: a systematic review","volume":"110","author":"Georgiou","year":"2013","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.arcped.2019.05.010_bib0455","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S1474-4422(13)70058-9","article-title":"Cooling of children with severe traumatic brain injury","volume":"12","author":"Hutchison","year":"2013","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.arcped.2019.05.010_bib0460","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s00381-013-2076-x","article-title":"Is therapeutic hypothermia beneficial for pediatric patients with traumatic brain injury? A meta-analysis","volume":"29","author":"Ma","year":"2013","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.arcped.2019.05.010_bib0465","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.wneu.2014.12.010","article-title":"Meta-analysis of the efficacy and safety of therapeutic hypothermia in children with acute traumatic brain injury","volume":"83","author":"Zhang","year":"2015","journal-title":"World Neurosurg"},{"key":"10.1016\/j.arcped.2019.05.010_bib0470","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/PCC.0000000000001098","article-title":"Updating evidence for using hypothermia in pediatric severe traumatic brain injury: conventional and bayesian meta-analytic perspectives","volume":"18","author":"Tasker","year":"2017","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0475","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.1097\/CCM.0b013e3181a59357","article-title":"No child left behind: enrolling children and adults simultaneously in critical care randomized trials","volume":"37","author":"Halpern","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0480","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1177\/1740774509339238","article-title":"Bayesian design using adult data to augment pediatric trials","volume":"6","author":"Schoenfeld","year":"2009","journal-title":"Clin Trials"},{"key":"10.1016\/j.arcped.2019.05.010_bib0485","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1440-1789.2010.01155.x","article-title":"Mild hypothermia pretreatment protects against pilocarpine-induced status epilepticus and neuronal apoptosis in immature rats","volume":"31","author":"Yu","year":"2011","journal-title":"Neuropathology"},{"key":"10.1016\/j.arcped.2019.05.010_bib0490","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.brainres.2012.01.022","article-title":"Deep hypothermia terminates status epilepticus \u2013 an experimental study","volume":"1446","author":"Kowski","year":"2012","journal-title":"Brain Res"},{"key":"10.1016\/j.arcped.2019.05.010_bib0495","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.nbd.2006.05.008","article-title":"Anticonvulsant properties of hypothermia in experimental status epilepticus","volume":"23","author":"Schmitt","year":"2006","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.arcped.2019.05.010_bib0500","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1755-5949.2010.00168.x","article-title":"Hypothermia reduces brain edema, spontaneous recurrent seizure attack, and learning memory deficits in the kainic-acid treated rats","volume":"17","author":"Wang","year":"2011","journal-title":"CNS Neurosci Ther"},{"key":"10.1016\/j.arcped.2019.05.010_bib0505","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1002\/ana.1021","article-title":"Focal cooling rapidly terminates experimental neocortical seizures","volume":"49","author":"Yang","year":"2001","journal-title":"Ann Neurol"},{"key":"10.1016\/j.arcped.2019.05.010_bib0510","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0006-8993(00)03285-6","article-title":"The effects of cooling and rewarming on the neuronal activity of pyramidal neurons in guinea pig hippocampal slices","volume":"893","author":"Aihara","year":"2001","journal-title":"Brain Res"},{"key":"10.1016\/j.arcped.2019.05.010_bib0515","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1056\/NEJMoa1608193","article-title":"Hypothermia for neuroprotection in convulsive status epilepticus","volume":"375","author":"Legriel","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0520","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1111\/epi.12331","article-title":"Hypothermia for pediatric refractory status epilepticus","volume":"54","author":"Guilliams","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.arcped.2019.05.010_bib0525","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.ejpn.2009.12.001","article-title":"Mild hypothermia for refractory focal status epilepticus in an infant with hemimegalencephaly","volume":"14","author":"Elting","year":"2010","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.arcped.2019.05.010_bib0530","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.braindev.2015.09.003","article-title":"Targed temperature management for acute encephalopathy in a Japanese secondary emergency medical care hospital","volume":"38","author":"Murata","year":"2016","journal-title":"Brain Dev"},{"key":"10.1016\/j.arcped.2019.05.010_bib0535","first-page":"1897","article-title":"Guidelines for the management of influenza-associated encephalopathy","volume":"64","author":"Morishima","year":"2006","journal-title":"Nihon Rinsho"},{"key":"10.1016\/j.arcped.2019.05.010_bib0540","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1097\/PCC.0000000000000763","article-title":"Targeted temperature management after pediatric cardiac arrest due to drowning: outcomes and complications","volume":"17","author":"Moler","year":"2016","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0545","article-title":"Successful therapeutic hypothermia for children surviving near-hanging","volume":"34","author":"Plastra","year":"2016","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.arcped.2019.05.010_bib0550","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1136\/adc.2009.180554","article-title":"Determinants of outcomes following acute child encephalopathy and encephalitis: pivotal effect of early and delayed cooling","volume":"96","author":"Kawano","year":"2011","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.arcped.2019.05.010_bib0555","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.jhep.2016.05.006","article-title":"Hypothermia in acute liver failure: what got lost in translation?","volume":"65","author":"Porcher","year":"2016","journal-title":"J Hepatol"},{"key":"10.1016\/j.arcped.2019.05.010_bib0560","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1007\/s00431-012-1769-6","article-title":"Rescue hypothermia for refractory hypercapnia","volume":"171","author":"Pietrini","year":"2012","journal-title":"Eur J Pediatr"}],"container-title":["Archives de P\u00e9diatrie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0929693X19300983?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0929693X19300983?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T14:52:12Z","timestamp":1760539932000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0929693X19300983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":56,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["S0929693X19300983"],"URL":"https:\/\/doi.org\/10.1016\/j.arcped.2019.05.010","relation":{},"ISSN":["0929-693X"],"issn-type":[{"value":"0929-693X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapeutic hypothermia in children: Which indications remain in 2018?","name":"articletitle","label":"Article Title"},{"value":"Archives de P\u00e9diatrie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arcped.2019.05.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 French Society of Pediatrics. Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}