{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T23:10:04Z","timestamp":1785798604220,"version":"3.56.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives de P\u00e9diatrie"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.arcped.2022.05.007","type":"journal-article","created":{"date-parts":[[2022,6,12]],"date-time":"2022-06-12T07:12:51Z","timestamp":1655017971000},"page":"434-438","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Bone deformities in patients with neurofibromatosis type 1: Single-center experience"],"prefix":"10.1016","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5115-8890","authenticated-orcid":false,"given":"E.","family":"Tekin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arcped.2022.05.007_bib0001","first-page":"575","article-title":"National institutes of health consensus development conference","volume":"45","year":"1988","journal-title":"Arch Neurol"},{"key":"10.1016\/j.arcped.2022.05.007_bib0002","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/B978-0-444-64076-5.00051-X","article-title":"Neurofibromatosis type 1","volume":"148","author":"Cimino","year":"2018","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.arcped.2022.05.007_bib0003","doi-asserted-by":"crossref","first-page":"e17226","DOI":"10.1097\/MD.0000000000017226","article-title":"Unusual form of the distal bone defect of ulna with neurofibromatosis type 1: a case report","volume":"98","author":"Shen","year":"2019","journal-title":"Medicine"},{"key":"10.1016\/j.arcped.2022.05.007_bib0004","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s13023-017-0756-4","article-title":"Congenital anomalies in neurofibromatosis 1: a retrospective register-based total population study","volume":"13","author":"Lepp\u00e4virta","year":"2018","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.arcped.2022.05.007_bib0005","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1002\/ajmg.c.30296","article-title":"The musculoskeletal phenotype of the RASopathies","volume":"157","author":"Stevenson","year":"2011","journal-title":"Am J Med Genet Part C Semin Med Genet"},{"key":"10.1016\/j.arcped.2022.05.007_bib0006","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1097\/01241398-199905000-00005","article-title":"Congenital bone malformations in patients with neurofibromatosis type 1 (Nf1)","volume":"19","author":"Ruggieri","year":"1999","journal-title":"J Pediatr Orthop"},{"key":"10.1016\/j.arcped.2022.05.007_bib0007","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1136\/jmg.2008.061895","article-title":"Bone health and fracture rate in individuals with neurofibromatosis 1 (NF1)","volume":"46","author":"Tucker","year":"2009","journal-title":"J Med Genet"},{"key":"10.1016\/j.arcped.2022.05.007_bib0008","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1002\/ajmg.a.35541","article-title":"Fractures in children with neurofibromatosis type 1 from two NF clinics","volume":"161A","author":"George-Abraham","year":"2013","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.arcped.2022.05.007_bib0009","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3171\/2013.1.PEDS12409","article-title":"Calvarial defects and skeletal dysplasia in patients with neurofibromatosis type 1","volume":"11","author":"Arrington","year":"2013","journal-title":"J Neurosurg Pediatr"},{"key":"10.1016\/j.arcped.2022.05.007_bib0010","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1002\/ajmg.a.33045","article-title":"Skeletal abnormalities in neurofibromatosis type 1: approaches to therapeutic options","volume":"149A","author":"Elefteriou","year":"2009","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.arcped.2022.05.007_bib0011","doi-asserted-by":"crossref","first-page":"S244","DOI":"10.1097\/00007632-199208001-00005","article-title":"Prevalence of scoliosis in neurofibromatosis","volume":"17","author":"Akbarnia","year":"1992","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.1016\/j.arcped.2022.05.007_bib0012","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1002\/ajmg.a.31754","article-title":"Associations of osseous abnormalities in neurofibromatosis 1","volume":"143A","author":"Alwan","year":"2007","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.arcped.2022.05.007_bib0013","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1097\/GIM.0b013e3180986e05","article-title":"The use of anterolateral bowing of the lower leg in the diagnostic criteria for neurofibromatosis type 1","volume":"9","author":"Stevenson","year":"2007","journal-title":"Genet Med"},{"key":"10.1016\/j.arcped.2022.05.007_bib0014","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1002\/ajmg.a.35753","article-title":"Evaluation of tibial osteopathy occurrence in neurofibromatosis type 1 Italian patients","volume":"161A","author":"Morcaldi","year":"2013","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.arcped.2022.05.007_bib0015","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/S1474-4422(14)70063-8","article-title":"Neurofibromatosis type 1: a multidisciplinary approach to care","volume":"13","author":"Hirbe","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.arcped.2022.05.007_bib0016","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1007\/s00381-020-04775-4","article-title":"Management of spinal deformities and tibial pseudarthrosis in children with neurofibromatosis type 1 (NF-1)","volume":"36","author":"Mladenov","year":"2020","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.arcped.2022.05.007_bib0017","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1002\/ajmg.a.35417","article-title":"A benign form of congenital anterolateral bowing of the tibia associated with ipsilateral polydactyly of the hallux: case report and literature review","volume":"158A","author":"Han","year":"2012","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.arcped.2022.05.007_bib0018","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/MCD.0b013e32832d06d7","article-title":"Congenital anterolateral bowing of the tibia with ipsilateral polydactyly of the great toe associated with cerebral cyst: a new entity?","volume":"18","author":"Breckpot","year":"2009","journal-title":"Clin Dysmorphol"},{"key":"10.1016\/j.arcped.2022.05.007_bib0019","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1752-1947-1-54","article-title":"Congenital anterolateral tibial bowing and polydactyly: a case report","volume":"1","author":"Lemire","year":"2007","journal-title":"J Med Case Rep"},{"key":"10.1016\/j.arcped.2022.05.007_bib0020","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1302\/0301-620X.87B2.15132","article-title":"Pathomorphology and treatment of congenital anterolateral bowing of the tibia associated with duplication of the hallux","volume":"87","author":"Manner","year":"2005","journal-title":"J Bone Jt Surg Br"},{"key":"10.1016\/j.arcped.2022.05.007_bib0021","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF02011043","article-title":"Minor tibial duplication: a new cause of congenital bowing of the tibia","volume":"21","author":"Adamsbaum","year":"1991","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.arcped.2022.05.007_bib0022","doi-asserted-by":"crossref","first-page":"e1549","DOI":"10.1097\/GOX.0000000000001549","article-title":"Genetic overview of syndactyly and polydactyly","volume":"5","author":"Ahmed","year":"2017","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"10.1016\/j.arcped.2022.05.007_bib0023","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1055\/s-2004-817884","article-title":"Genetics of congenital hand anomalies","volume":"36","author":"Schwabe","year":"2004","journal-title":"Handchir Mikrochir Plast Chir"},{"key":"10.1016\/j.arcped.2022.05.007_bib0024","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2019-0660","article-title":"Counc\u0131l on genetics; Amer\u0131can College of medical genetics and genomics. Health supervision for children with neurofibromatosis type 1","volume":"143","author":"Miller","year":"2019","journal-title":"Pediatrics"},{"key":"10.1016\/j.arcped.2022.05.007_bib0025","doi-asserted-by":"crossref","first-page":"S141","DOI":"10.4103\/0976-3147.116473","article-title":"Optic pathway glioma, scoliosis, Chiari type 1 malformation, and syringomyelia in a patient with neurofibromatosis type 1","volume":"4","author":"Incec\u0131k","year":"2013","journal-title":"J Neurosci Rural Pract"},{"key":"10.1016\/j.arcped.2022.05.007_bib0026","first-page":"335","article-title":"Pseudoarthrosis of the hand in neurofibromatosis type 1: a case report","volume":"55","author":"\u0130ncecik","year":"2013","journal-title":"Turk J Pediatr"}],"container-title":["Archives de P\u00e9diatrie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0929693X22001221?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0929693X22001221?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T14:54:40Z","timestamp":1760540080000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0929693X22001221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["S0929693X22001221"],"URL":"https:\/\/doi.org\/10.1016\/j.arcped.2022.05.007","relation":{},"ISSN":["0929-693X"],"issn-type":[{"value":"0929-693X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bone deformities in patients with neurofibromatosis type 1: Single-center experience","name":"articletitle","label":"Article Title"},{"value":"Archives de P\u00e9diatrie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arcped.2022.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 French Society of Pediatrics. Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}