{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T06:39:23Z","timestamp":1776753563121,"version":"3.51.2"},"reference-count":121,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ageing Research Reviews"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.arr.2012.03.005","type":"journal-article","created":{"date-parts":[[2012,4,5]],"date-time":"2012-04-05T11:33:31Z","timestamp":1333625611000},"page":"450-459","source":"Crossref","is-referenced-by-count":21,"title":["The regulation of A\u03b2PP expression by RNA-binding proteins"],"prefix":"10.1016","volume":"11","author":[{"given":"Cara J.","family":"Westmark","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James S.","family":"Malter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arr.2012.03.005_bib0005","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1006\/mcne.2000.0834","article-title":"Developmental regulation of amyloid precursor protein at the neuromuscular junction in mouse skeletal muscle","volume":"15","author":"Akaaboune","year":"2000","journal-title":"Molecular and Cellular Neuroscience"},{"key":"10.1016\/j.arr.2012.03.005_bib0010","first-page":"3444","article-title":"The rck\/p54 candidate proto-oncogene product is a 54-kilodalton D-E-A-D box protein differentially expressed in human and mouse tissues","volume":"55","author":"Akao","year":"1995","journal-title":"Cancer Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0015","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0169-328X(99)00158-8","article-title":"TGF-beta(1), regulation of Alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: mRNA stabilization","volume":"71","author":"Amara","year":"1999","journal-title":"Brain Research Molecular Brain Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0020","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1099\/0022-1317-80-10-2629","article-title":"Interaction of YB1 with human immunodeficiency virus type 1 tat and TAR RNA modulates viral promoter activity","volume":"80","author":"Ansari","year":"1999","journal-title":"Journal of General Virology"},{"key":"10.1016\/j.arr.2012.03.005_bib0025","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nrn1667","article-title":"From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome","volume":"6","author":"Bagni","year":"2005","journal-title":"Nature Reviews Neuroscience"},{"key":"10.1016\/j.arr.2012.03.005_bib0030","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.ceb.2009.03.005","article-title":"Polysomes, P bodies and stress granules: states and fates of eukaryotic mRNAs","volume":"21","author":"Balagopal","year":"2009","journal-title":"Current Opinion in Cell Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0035","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1517\/14728222.2010.525352","article-title":"Novel drug targets based on metallobiology of Alzheimer's disease","volume":"14","author":"Bandyopadhyay","year":"2010","journal-title":"Expert Opinion on Therapeutic Targets"},{"key":"10.1016\/j.arr.2012.03.005_bib0040","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.neuron.2006.10.028","article-title":"Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies","volume":"52","author":"Barbee","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.arr.2012.03.005_bib0045","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1038\/78682","article-title":"Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease","volume":"6","author":"Bard","year":"2000","journal-title":"Nature Medicine"},{"key":"10.1016\/j.arr.2012.03.005_bib0050","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.tins.2004.04.009","article-title":"The mGluR theory of fragile X mental retardation","volume":"27","author":"Bear","year":"2004","journal-title":"Trends in Neurosciences"},{"key":"10.1016\/j.arr.2012.03.005_bib0055","doi-asserted-by":"crossref","first-page":"6625","DOI":"10.1093\/nar\/17.16.6625","article-title":"Protein kinase NII and the regulation of rDNA transcription in mammalian cells","volume":"17","author":"Belenguer","year":"1989","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0060","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0092-8674(89)90241-9","article-title":"Major nucleolar proteins shuttle between nucleus and cytoplasm","volume":"56","author":"Borer","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.arr.2012.03.005_bib0065","doi-asserted-by":"crossref","first-page":"19025","DOI":"10.1074\/jbc.273.30.19025","article-title":"Nucleolin interacts with several ribosomal proteins through its RGG domain","volume":"273","author":"Bouvet","year":"1998","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0070","doi-asserted-by":"crossref","first-page":"28297","DOI":"10.1074\/jbc.270.47.28297","article-title":"Sequence-specific RNA recognition by the Xenopus Y-box proteins. An essential role for the cold shock domain","volume":"270","author":"Bouvet","year":"1995","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0075","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1128\/MCB.11.5.2460","article-title":"An A+U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro","volume":"11","author":"Brewer","year":"1991","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0080","doi-asserted-by":"crossref","first-page":"28057","DOI":"10.1074\/jbc.273.43.28057","article-title":"Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3","volume":"273","author":"Brockstedt","year":"1998","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0085","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0092-8674(01)00568-2","article-title":"Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome","volume":"107","author":"Brown","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.arr.2012.03.005_bib0090","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1016\/j.neurobiolaging.2008.02.011","article-title":"Rck\/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines","volume":"30","author":"Broytman","year":"2008","journal-title":"Neurobiology of Aging"},{"key":"10.1016\/j.arr.2012.03.005_bib0095","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/jnr.10876","article-title":"Anti-abeta: the good, the bad, and the unforeseen","volume":"75","author":"Broytman","year":"2004","journal-title":"Journal of Neuroscience Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0100","doi-asserted-by":"crossref","first-page":"5970","DOI":"10.4049\/jimmunol.167.10.5970","article-title":"Y box-binding factor promotes eosinophil survival by stabilizing granulocyte-macrophage colony-stimulating factor mRNA","volume":"167","author":"Capowski","year":"2001","journal-title":"Journal of Immunology"},{"key":"10.1016\/j.arr.2012.03.005_bib0105","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1073\/pnas.83.6.1670","article-title":"Identification of a common nucleotide sequence in the 3\u2032-untranslated region of mRNA molecules specifying inflammatory mediators","volume":"83","author":"Caput","year":"1986","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.arr.2012.03.005_bib0110","doi-asserted-by":"crossref","first-page":"7925","DOI":"10.1128\/MCB.19.12.7925","article-title":"Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex","volume":"19","author":"Ceman","year":"1999","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0115","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1038\/415462a","article-title":"Nerve inflammation halts trial for Alzheimer's drug","volume":"415","author":"Check","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.arr.2012.03.005_bib0120","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1101\/gad.14.10.1236","article-title":"Nucleolin and YB1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation","volume":"14","author":"Chen","year":"2000","journal-title":"Genes & Development"},{"key":"10.1016\/j.arr.2012.03.005_bib0125","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0306-4522(03)00406-8","article-title":"The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences","volume":"120","author":"Chen","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.arr.2012.03.005_bib0130","doi-asserted-by":"crossref","first-page":"31217","DOI":"10.1074\/jbc.M110.149161","article-title":"Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1","volume":"285","author":"Cho","year":"2010","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0135","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1126\/science.3952495","article-title":"Heterogeneous nuclear ribonucleoproteins: role in RNA splicing","volume":"231","author":"Choi","year":"1986","journal-title":"Science"},{"key":"10.1016\/j.arr.2012.03.005_bib0140","doi-asserted-by":"crossref","first-page":"7471","DOI":"10.1073\/pnas.81.23.7471","article-title":"Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex (hnRNP): a unique supramolecular assembly","volume":"81","author":"Choi","year":"1984","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.arr.2012.03.005_bib0145","doi-asserted-by":"crossref","first-page":"e210","DOI":"10.1371\/journal.pbio.0040210","article-title":"Translation repression in human cells by microRNA-induced gene silencing requires RCK\/p54","volume":"4","author":"Chu","year":"2006","journal-title":"PLoS Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0150","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/sj.emboj.7600954","article-title":"Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe\u2013S cluster","volume":"25","author":"Clarke","year":"2006","journal-title":"EMBO Journal"},{"key":"10.1016\/j.arr.2012.03.005_bib0155","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1017\/S135583820101994X","article-title":"The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes","volume":"7","author":"Coller","year":"2001","journal-title":"RNA"},{"key":"10.1016\/j.arr.2012.03.005_bib0160","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1002\/j.1460-2075.1991.tb07715.x","article-title":"Human erythroid 5-aminolevulinate synthase: promoter analysis and identification of an iron-responsive element in the mRNA","volume":"10","author":"Cox","year":"1991","journal-title":"EMBO Journal"},{"key":"10.1016\/j.arr.2012.03.005_bib0165","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1101\/gad.1276805","article-title":"Kissing complex RNAs mediate interaction between the fragile-X mental retardation protein KH2 domain and brain polyribosomes","volume":"19","author":"Darnell","year":"2005","journal-title":"Genes & Development"},{"key":"10.1016\/j.arr.2012.03.005_bib0170","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0092-8674(01)00566-9","article-title":"Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function","volume":"107","author":"Darnell","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.arr.2012.03.005_bib0175","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1002\/j.1460-2075.1992.tb05382.x","article-title":"Alternative polyadenylation of the amyloid protein precursor mRNA regulates translation","volume":"11","author":"de Sauvage","year":"1992","journal-title":"EMBO Journal"},{"key":"10.1016\/j.arr.2012.03.005_bib0180","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0003-9861(91)90161-B","article-title":"Distribution and activity of alternatively spliced Alzheimer amyloid peptide precursor and scrapie PrP mRNAs on rat brain polysomes","volume":"288","author":"Denman","year":"1991","journal-title":"Archives of Biochemistry and Biophysics"},{"key":"10.1016\/j.arr.2012.03.005_bib0185","first-page":"497","article-title":"The quantity of nucleolar proteins nucleolin and protein B23 is related to cell doubling time in human cancer cells","volume":"73","author":"Derenzini","year":"1995","journal-title":"Laboratory Investigation"},{"key":"10.1016\/j.arr.2012.03.005_bib0190","doi-asserted-by":"crossref","first-page":"7322","DOI":"10.1073\/pnas.85.19.7322","article-title":"Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box","volume":"85","author":"Didier","year":"1988","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.arr.2012.03.005_bib0195","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/S0006-291X(03)00766-6","article-title":"The fragile X mental retardation protein interacts with U-rich RNAs in a yeast three-hybrid system","volume":"305","author":"Dolzhanskaya","year":"2003","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.arr.2012.03.005_bib0200","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/0014-4827(88)90397-7","article-title":"Effects of anti-C23 (nucleolin) antibody on transcription of ribosomal DNA in chironomus salivary gland cells","volume":"178","author":"Egyhazi","year":"1988","journal-title":"Experimental Cell Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0205","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1432-1033.1988.tb14224.x","article-title":"A major nucleolar protein, nucleolin, induces chromatin decondensation by binding to histone H1","volume":"175","author":"Erard","year":"1988","journal-title":"European Journal of Biochemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0210","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nrm2080","article-title":"P bodies: at the crossroads of post-transcriptional pathways","volume":"8","author":"Eulalio","year":"2007","journal-title":"Nature Reviews Molecular Cell Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0215","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.bbaexp.2005.08.005","article-title":"Role of nucleolin in posttranscriptional control of MMP-9 expression","volume":"1731","author":"Fahling","year":"2005","journal-title":"Biochimica et Biophysica Acta"},{"key":"10.1016\/j.arr.2012.03.005_bib0220","doi-asserted-by":"crossref","first-page":"9084","DOI":"10.1128\/MCB.20.23.9084-9091.2000","article-title":"Heterogeneous nuclear ribonucleoproteins C1 and C2 associate with the RNA component of human telomerase","volume":"20","author":"Ford","year":"2000","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0225","first-page":"144","article-title":"Phase II double blind controlled study of a new anxiolytic, fenobam (McN-3377) vs placebo","volume":"274","author":"Friedmann","year":"1980","journal-title":"Current Therapeutic Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0230","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.1016\/S0021-9258(18)49970-X","article-title":"The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs","volume":"266","author":"Gillis","year":"1991","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0235","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1093\/emboj\/17.5.1476","article-title":"Nucleolin functions in the first step of ribosomal RNA processing","volume":"17","author":"Ginisty","year":"1998","journal-title":"EMBO Journal"},{"key":"10.1016\/j.arr.2012.03.005_bib0240","doi-asserted-by":"crossref","first-page":"8881","DOI":"10.1016\/S0021-9258(18)52955-0","article-title":"Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences","volume":"268","author":"Hamilton","year":"1993","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0245","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1055\/s-0037-1613396","article-title":"Posttranscriptional regulation of PAI-1 gene expression","volume":"89","author":"Heaton","year":"2003","journal-title":"Thrombosis and Haemostasis"},{"key":"10.1016\/j.arr.2012.03.005_bib0250","doi-asserted-by":"crossref","first-page":"3341","DOI":"10.1074\/jbc.M006538200","article-title":"Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the type-1 plasminogen activator inhibitor mRNA","volume":"276","author":"Heaton","year":"2001","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0255","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1128\/MCB.23.1.280-288.2003","article-title":"The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2","volume":"23","author":"Holcik","year":"2003","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0260","doi-asserted-by":"crossref","first-page":"3472","DOI":"10.1128\/MCB.05587-11","article-title":"Prevention of transcriptional silencing by a replicator-binding complex consisting of SWI\/SNF, MeCP1, and hnRNP C1\/C2","volume":"31","author":"Huang","year":"2011","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0265","doi-asserted-by":"crossref","first-page":"7746","DOI":"10.1073\/pnas.122205699","article-title":"Altered synaptic plasticity in a mouse model of fragile X mental retardation","volume":"99","author":"Huber","year":"2002","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.arr.2012.03.005_bib0270","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0169-328X(03)00027-5","article-title":"Cellular and subcellular distributions of translation initiation, elongation and release factors in rat hippocampus","volume":"111","author":"Inamura","year":"2003","journal-title":"Brain Research Molecular Brain Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0275","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1093\/cercor\/10.10.1038","article-title":"Dendritic spine structural anomalies in fragile-X mental retardation syndrome","volume":"10","author":"Irwin","year":"2000","journal-title":"Cerebral Cortex"},{"key":"10.1016\/j.arr.2012.03.005_bib0280","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/329489a0","article-title":"At the heart of the nucleolus","volume":"329","author":"Jordan","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.arr.2012.03.005_bib0285","doi-asserted-by":"crossref","first-page":"5296","DOI":"10.1091\/mbc.E08-06-0562","article-title":"eEF1A is a novel component of the mammalian nuclear protein export machinery","volume":"19","author":"Khacho","year":"2008","journal-title":"Molecular Biology of the Cell"},{"key":"10.1016\/j.arr.2012.03.005_bib0290","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1002\/jnr.490420305","article-title":"A 110-kD nuclear shuttling protein, nucleolin, binds to the neurite-promoting IKVAV site of laminin-1","volume":"42","author":"Kibbey","year":"1995","journal-title":"Journal of Neuroscience Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0295","doi-asserted-by":"crossref","first-page":"4983","DOI":"10.1074\/jbc.270.10.4983","article-title":"Translational repressor activity is equivalent and is quantitatively predicted by in vitro RNA binding for two iron-responsive element-binding proteins, IRP1 and IRP2","volume":"270","author":"Kim","year":"1995","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0300","doi-asserted-by":"crossref","first-page":"6331","DOI":"10.1523\/JNEUROSCI.22-15-06331.2002","article-title":"Reversible memory loss in a mouse transgenic model of Alzheimer's disease","volume":"22","author":"Kotilinek","year":"2002","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.arr.2012.03.005_bib0305","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1093\/hmg\/10.4.329","article-title":"Evidence that fragile X mental retardation protein is a negative regulator of translation","volume":"10","author":"Laggerbauer","year":"2001","journal-title":"Human Molecular Genetics"},{"key":"10.1016\/j.arr.2012.03.005_bib0310","doi-asserted-by":"crossref","first-page":"7984","DOI":"10.1128\/MCB.14.12.7984","article-title":"AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U\/A)(U\/A)","volume":"14","author":"Lagnado","year":"1994","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0315","doi-asserted-by":"crossref","first-page":"4311","DOI":"10.1128\/MCB.19.6.4311","article-title":"Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA","volume":"19","author":"Lai","year":"1999","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0320","first-page":"95-101","article-title":"Fenobam: another anxiolytic?","volume":"31","author":"Lapierre","year":"1982","journal-title":"Current Therapeutic Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0325","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/nsmb.1815","article-title":"hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies","volume":"17","author":"Lee","year":"2010","journal-title":"Nature Structural & Molecular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0330","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1093\/nar\/29.11.2276","article-title":"The fragile X mental retardation protein inhibits translation via interacting with mRNA","volume":"29","author":"Li","year":"2001","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0335","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.bbrc.2010.12.053","article-title":"MicroRNA-101 downregulates Alzheimer's amyloid-beta precursor protein levels in human cell cultures and is differentially expressed","volume":"404","author":"Long","year":"2011","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.arr.2012.03.005_bib0340","doi-asserted-by":"crossref","first-page":"15012","DOI":"10.1073\/pnas.0507596102","article-title":"Heterogeneous nuclear ribonucleoprotein C1\/C2, MeCP1, and SWI\/SNF form a chromatin remodeling complex at the beta-globin locus control region","volume":"102","author":"Mahajan","year":"2005","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.arr.2012.03.005_bib0345","doi-asserted-by":"crossref","first-page":"200","DOI":"10.2174\/156720510791050957","article-title":"Fragile X syndrome and Alzheimer's disease: another story about APP and beta-amyloid","volume":"7","author":"Malter","year":"2010","journal-title":"Current Alzheimer Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0350","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1126\/science.2814487","article-title":"Identification of an AUUUA-specific messenger RNA binding protein","volume":"246","author":"Malter","year":"1989","journal-title":"Science"},{"key":"10.1016\/j.arr.2012.03.005_bib0355","doi-asserted-by":"crossref","first-page":"4245","DOI":"10.1073\/pnas.82.12.4245","article-title":"Amyloid plaque core protein in Alzheimer disease and Down syndrome","volume":"82","author":"Masters","year":"1985","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.arr.2012.03.005_bib0360","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1093\/hmg\/11.24.3007","article-title":"Trapping of messenger RNA by fragile X mental retardation protein into cytoplasmic granules induces translation repression","volume":"11","author":"Mazroui","year":"2002","journal-title":"Human Molecular Genetics"},{"key":"10.1016\/j.arr.2012.03.005_bib0365","doi-asserted-by":"crossref","first-page":"3028","DOI":"10.1128\/MCB.17.6.3028","article-title":"Human La protein: a stabilizer of histone mRNA","volume":"17","author":"McLaren","year":"1997","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0370","doi-asserted-by":"crossref","first-page":"5947","DOI":"10.1128\/MCB.20.16.5947-5959.2000","article-title":"A U-rich element in the 5\u2032-untranslated region is necessary for the translation of p27 mRNA","volume":"20","author":"Millard","year":"2000","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0375","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1091\/mbc.E09-01-0035","article-title":"Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly","volume":"20","author":"Minshall","year":"2009","journal-title":"Molecular Biology of the Cell"},{"key":"10.1016\/j.arr.2012.03.005_bib0380","doi-asserted-by":"crossref","first-page":"37389","DOI":"10.1074\/jbc.M704629200","article-title":"CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes","volume":"282","author":"Minshall","year":"2007","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0385","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0896-6273(03)00034-5","article-title":"RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice","volume":"37","author":"Miyashiro","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.arr.2012.03.005_bib0390","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1159\/000090366","article-title":"Mechanisms of A-beta plaque clearance following passive A-beta immunization","volume":"2","author":"Morgan","year":"2005","journal-title":"Neurodegenerative Diseases"},{"key":"10.1016\/j.arr.2012.03.005_bib0395","doi-asserted-by":"crossref","first-page":"5430","DOI":"10.2174\/092986711798194351","article-title":"Interacting with gamma-secretase for treating Alzheimer's disease: from inhibition to modulation","volume":"18","author":"Panza","year":"2011","journal-title":"Current Medicinal Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0400","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.molcel.2007.02.011","article-title":"P bodies and the control of mRNA translation and degradation","volume":"25","author":"Parker","year":"2007","journal-title":"Molecular Cell"},{"key":"10.1016\/j.arr.2012.03.005_bib0405","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1750-1326-3-10","article-title":"MicroRNAs can regulate human APP levels","volume":"3","author":"Patel","year":"2008","journal-title":"Molecular Neurodegeneration"},{"key":"10.1016\/j.arr.2012.03.005_bib0410","first-page":"119","article-title":"Fenobam in anxious outpatients","volume":"274","author":"Pecknold","year":"1980","journal-title":"Current Therapeutic Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0415","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/00004714-198204000-00010","article-title":"Treatment of anxiety using fenobam (a nonbenzodiazepine) in a double-blind standard (diazepam) placebo-controlled study","volume":"2","author":"Pecknold","year":"1982","journal-title":"Journal of Clinical Psychopharmacology"},{"key":"10.1016\/j.arr.2012.03.005_bib0420","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1126\/science.1078259","article-title":"Cerebral hemorrhage after passive anti-Abeta immunotherapy","volume":"298","author":"Pfeifer","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.arr.2012.03.005_bib0425","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1523\/JNEUROSCI.4337-04.2005","article-title":"Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta","volume":"25","author":"Racke","year":"2005","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.arr.2012.03.005_bib0430","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1046\/j.1471-4159.2000.0740052.x","article-title":"Growth factor-mediated stabilization of amyloid precursor protein mRNA is mediated by a conserved 29-nucleotide sequence in the 3\u2032-untranslated region","volume":"74","author":"Rajagopalan","year":"2000","journal-title":"Journal of Neurochemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0435","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.1093\/nar\/26.14.3418","article-title":"hnRNP C increases amyloid precursor protein (APP) production by stabilizing APP mRNA","volume":"26","author":"Rajagopalan","year":"1998","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0440","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1101\/gad.7.9.1725","article-title":"Masking mRNA from translation in somatic cells","volume":"7","author":"Ranjan","year":"1993","journal-title":"Genes & Development"},{"key":"10.1016\/j.arr.2012.03.005_bib0445","doi-asserted-by":"crossref","first-page":"28257","DOI":"10.1074\/jbc.270.47.28257","article-title":"Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease","volume":"270","author":"Rockenstein","year":"1995","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0450","doi-asserted-by":"crossref","first-page":"45518","DOI":"10.1074\/jbc.M207435200","article-title":"An iron-responsive element type II in the 5\u2032-untranslated region of the Alzheimer's amyloid precursor protein transcript","volume":"277","author":"Rogers","year":"2002","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0455","doi-asserted-by":"crossref","first-page":"6421","DOI":"10.1074\/jbc.274.10.6421","article-title":"Translation of the Alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5\u2032-untranslated region sequences","volume":"274","author":"Rogers","year":"1999","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0460","doi-asserted-by":"crossref","first-page":"499","DOI":"10.4161\/cib.3.6.13172","article-title":"Post-transcriptional regulation of amyloid precursor protein by microRNAs and RNA binding proteins","volume":"3","author":"Ruberti","year":"2010","journal-title":"Communicative & Integrative Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0465","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1146\/annurev-pathol-011811-132457","article-title":"Molecular mechanisms of fragile X syndrome: a twenty-year perspective","volume":"7","author":"Santoro","year":"2012","journal-title":"Annual Review of Pathology"},{"key":"10.1016\/j.arr.2012.03.005_bib0470","doi-asserted-by":"crossref","first-page":"10855","DOI":"10.1074\/jbc.M309111200","article-title":"Identification of nucleolin as an AU-rich element binding protein involved in bcl-2 mRNA stabilization","volume":"279","author":"Sengupta","year":"2004","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0475","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/0092-8674(86)90341-7","article-title":"A conserved AU sequence from the 3\u2032 untranslated region of GM-CSF mRNA mediates selective mRNA degradation","volume":"46","author":"Shaw","year":"1986","journal-title":"Cell"},{"key":"10.1016\/j.arr.2012.03.005_bib0480","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0006-8993(92)91697-D","article-title":"Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons","volume":"592","author":"Shigematsu","year":"1992","journal-title":"Brain Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0485","doi-asserted-by":"crossref","first-page":"976","DOI":"10.4049\/jimmunol.173.2.976","article-title":"Nucleolin is a second component of the CD154 mRNA stability complex that regulates mRNA turnover in activated T cells","volume":"173","author":"Singh","year":"2004","journal-title":"Journal of Immunology"},{"key":"10.1016\/j.arr.2012.03.005_bib0490","doi-asserted-by":"crossref","first-page":"3624","DOI":"10.1038\/sj.emboj.7600824","article-title":"Homo- and heterodimerization of APP family members promotes intercellular adhesion","volume":"24","author":"Soba","year":"2005","journal-title":"EMBO Journal"},{"key":"10.1016\/j.arr.2012.03.005_bib0495","doi-asserted-by":"crossref","first-page":"7272","DOI":"10.1523\/JNEUROSCI.2306-04.2004","article-title":"Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells","volume":"24","author":"Stefani","year":"2004","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.arr.2012.03.005_bib0500","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1172\/JCI9075","article-title":"Thrombin activates a Y box-binding protein (DNA-binding protein B) in endothelial cells","volume":"106","author":"Stenina","year":"2000","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.arr.2012.03.005_bib0505","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S1097-2765(01)00329-X","article-title":"DExD\/H box RNA helicases: from generic motors to specific dissociation functions","volume":"8","author":"Tanner","year":"2001","journal-title":"Molecular Cell"},{"key":"10.1016\/j.arr.2012.03.005_bib0510","doi-asserted-by":"crossref","first-page":"31609","DOI":"10.1074\/jbc.M002354200","article-title":"Thyrotropin-releasing hormone and epidermal growth factor regulate iron-regulatory protein binding in pituitary cells via protein kinase C-dependent and -independent signaling pathways","volume":"275","author":"Thomson","year":"2000","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0515","doi-asserted-by":"crossref","first-page":"7171","DOI":"10.1523\/JNEUROSCI.16-22-07171.1996","article-title":"Translational machinery in dendrites of hippocampal neurons in culture","volume":"16","author":"Tiedge","year":"1996","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.arr.2012.03.005_bib0520","doi-asserted-by":"crossref","first-page":"7793","DOI":"10.1523\/JNEUROSCI.19-18-07793.1999","article-title":"The drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction","volume":"19","author":"Torroja","year":"1999","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.arr.2012.03.005_bib0525","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0378-1119(95)00207-M","article-title":"Human DNA helicase IV is nucleolin, an RNA helicase modulated by phosphorylation","volume":"160","author":"Tuteja","year":"1995","journal-title":"Gene"},{"key":"10.1016\/j.arr.2012.03.005_bib0530","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1038\/sj.leu.2400975","article-title":"Characterization of proteins binding the 3\u2032 regulatory region of the IL-3 gene in IL-3-dependent and autocrine-transformed hematopoietic cells","volume":"12","author":"Wang","year":"1998","journal-title":"Leukemia"},{"key":"10.1016\/j.arr.2012.03.005_bib0535","doi-asserted-by":"crossref","first-page":"e26549","DOI":"10.1371\/journal.pone.0026549","article-title":"Reversal of fragile X phenotypes by manipulation of APP\/Abeta levels in Fmr1 mice","volume":"6","author":"Westmark","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.arr.2012.03.005_bib0540","doi-asserted-by":"crossref","first-page":"e52","DOI":"10.1371\/journal.pbio.0050052","article-title":"FMRP mediates mGluR5-dependent translation of amyloid precursor protein","volume":"5","author":"Westmark","year":"2007","journal-title":"PLoS Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0545","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0169-328X(01)00112-7","article-title":"Extracellular-regulated kinase controls beta-amyloid precursor protein mRNA decay","volume":"90","author":"Westmark","year":"2001","journal-title":"Brain Research Molecular Brain Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0550","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1074\/jbc.M009435200","article-title":"Up-regulation of nucleolin mRNA and protein in peripheral blood mononuclear cells by extracellular-regulated kinase","volume":"276","author":"Westmark","year":"2001","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0555","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.neurobiolaging.2006.03.003","article-title":"Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells","volume":"27","author":"Westmark","year":"2006","journal-title":"Neurobiology of Aging"},{"key":"10.1016\/j.arr.2012.03.005_bib0560","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1093\/nar\/gkl409","article-title":"Xp54 and related (DDX6-like) RNA helicases: roles in messenger RNP assembly, translation regulation and RNA degradation","volume":"34","author":"Weston","year":"2006","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/j.arr.2012.03.005_bib0565","doi-asserted-by":"crossref","first-page":"6397","DOI":"10.1128\/MCB.10.12.6397","article-title":"A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal","volume":"10","author":"Wilusz","year":"1990","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0570","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.neulet.2005.04.040","article-title":"Reduced synaptic vesicle density and active zone size in mice lacking amyloid precursor protein (APP) and APP-like protein 2","volume":"384","author":"Yang","year":"2005","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.arr.2012.03.005_bib0575","doi-asserted-by":"crossref","first-page":"6068","DOI":"10.1128\/MCB.14.9.6068","article-title":"Purification and characterization of nucleolin and its identification as a transcription repressor","volume":"14","author":"Yang","year":"1994","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.arr.2012.03.005_bib0580","doi-asserted-by":"crossref","first-page":"10870","DOI":"10.1074\/jbc.272.16.10870","article-title":"A translation regulatory particle containing the Xenopus oocyte Y box protein mRNP3+4","volume":"272","author":"Yurkova","year":"1997","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0585","doi-asserted-by":"crossref","first-page":"17292","DOI":"10.1074\/jbc.270.29.17292","article-title":"Nucleolin and heterogeneous nuclear ribonucleoprotein C proteins specifically interact with the 3\u2032-untranslated region of amyloid protein precursor mRNA","volume":"270","author":"Zaidi","year":"1995","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0590","doi-asserted-by":"crossref","first-page":"24000","DOI":"10.1016\/S0021-9258(19)51038-9","article-title":"Multiple proteins interact at a unique cis-element in the 3\u2032-untranslated region of amyloid precursor protein mRNA","volume":"269","author":"Zaidi","year":"1994","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0595","doi-asserted-by":"crossref","first-page":"24007","DOI":"10.1016\/S0021-9258(19)51039-0","article-title":"Amyloid precursor protein mRNA stability is controlled by a 29-base element in the 3\u2032-untranslated region","volume":"269","author":"Zaidi","year":"1994","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.arr.2012.03.005_bib0600","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0092-8674(03)00079-5","article-title":"The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses","volume":"112","author":"Zalfa","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.arr.2012.03.005_bib0605","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1128\/MCB.15.4.2219","article-title":"The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation","volume":"15","author":"Zubiaga","year":"1995","journal-title":"Molecular and Cellular Biology"}],"container-title":["Ageing Research Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568163712000499?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568163712000499?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T07:14:02Z","timestamp":1641971642000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568163712000499"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":121,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S1568163712000499"],"URL":"https:\/\/doi.org\/10.1016\/j.arr.2012.03.005","relation":{},"ISSN":["1568-1637"],"issn-type":[{"value":"1568-1637","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}