{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T18:27:07Z","timestamp":1784917627244,"version":"3.55.0"},"reference-count":105,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ageing Research Reviews"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1016\/j.arr.2014.03.006","type":"journal-article","created":{"date-parts":[[2014,4,15]],"date-time":"2014-04-15T15:00:57Z","timestamp":1397574057000},"page":"1-11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":125,"special_numbering":"C","title":["Molecular action mechanisms of solar infrared radiation and heat on human skin"],"prefix":"10.1016","volume":"16","author":[{"given":"M.Ya.","family":"Akhalaya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.V.","family":"Maksimov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.B.","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Lademann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.E.","family":"Darvin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arr.2014.03.006_bib0005","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1159\/000343173","article-title":"Activation of TRPV4 strengthens the tight-junction barrier in human epidermal keratinocytes","volume":"26","author":"Akazawa","year":"2013","journal-title":"Skin Pharmacol. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0010","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1751-1097.1995.tb03973.x","article-title":"Two genes contribute to different extents to the heme oxygenase enzyme activity measured in cultured human skin fibroblasts and keratinocytes: implications for protection against oxidant stress","volume":"61","author":"Applegate","year":"1995","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0015","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1111\/exd.12124","article-title":"Radical protection in the visible and infrared by a hyperforin-rich cream\u2014in vivo versus ex vivo methods","volume":"22","author":"Arndt","year":"2013","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0020","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1001\/archderm.1979.04010100046019","article-title":"Thermal keratoses and squamous-cell carcinoma in situ associated with Erythema Ab igne","volume":"115","author":"Arrington","year":"1979","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0025","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1097\/CCO.0b013e328352eaa3","article-title":"Low-level laser therapy in the prevention and treatment of cancer therapy-induced mucositis: 2012 state of the art based on literature review and meta-analysis","volume":"24","author":"Bensadoun","year":"2012","journal-title":"Curr. Opin. Oncol."},{"key":"10.1016\/j.arr.2014.03.006_bib0030","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1136\/bjsm.2005.020842","article-title":"A randomised, placebo controlled trial of low level laser therapy for activated Achilles tendinitis with microdialysis measurement of peritendinous prostaglandin E2 concentrations","volume":"40","author":"Bjordal","year":"2006","journal-title":"Br. J. Sports Med."},{"key":"10.1016\/j.arr.2014.03.006_bib0035","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1038\/jid.2010.9","article-title":"Infrared A radiation influences the skin fibroblast transcriptome: mechanisms and consequences","volume":"130","author":"Calles","year":"2010","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0040","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/39807","article-title":"The capsaicin receptor: a heat-activated ion channel in the pain pathway","volume":"389","author":"Caterina","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.arr.2014.03.006_bib0045","doi-asserted-by":"crossref","first-page":"e54117","DOI":"10.1371\/journal.pone.0054117","article-title":"Middle infrared radiation induces G2\/M cell cycle arrest in A549 lung cancer cells","volume":"8","author":"Chang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.arr.2014.03.006_bib0050","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.0022-202X.2004.23550.x","article-title":"Heat modulation of tropoelastin, fibrillin-1, and matrix metalloproteinase-12 in human skin in vivo","volume":"124","author":"Chen","year":"2005","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0055","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jdermsci.2007.11.009","article-title":"Infrared plus visible light and heat from natural sunlight participate in the expression of MMPs and type I procollagen as well as infiltration of inflammatory cell in human skin in vivo","volume":"50","author":"Cho","year":"2008","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0060","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/jidsymp.2009.7","article-title":"Effects of infrared radiation and heat on human skin aging in vivo","volume":"14","author":"Cho","year":"2009","journal-title":"J. Invest. Dermatol. Symp. Proc."},{"key":"10.1016\/j.arr.2014.03.006_bib0065","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nature02196","article-title":"TRP channels as cellular sensors","volume":"426","author":"Clapham","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.arr.2014.03.006_bib0070","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/nrm3541","article-title":"The role of transcription-independent damage signals in the initiation of epithelial wound healing","volume":"14","author":"Cordeiro","year":"2013","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.arr.2014.03.006_bib0075","doi-asserted-by":"crossref","first-page":"10697","DOI":"10.3390\/ijms130910697","article-title":"Cell signaling through protein kinase C oxidation and activation","volume":"13","author":"Cosentino-Gomes","year":"2012","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0080","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1159\/000330486","article-title":"Comparison of transepidermal water loss and laser scanning microscopy measurements to assess their value in the characterization of cutaneous barrier defects","volume":"25","author":"Czaika","year":"2012","journal-title":"Skin Pharmacol. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0085","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1111\/j.1600-0625.2009.00946.x","article-title":"In vivo distribution of carotenoids in different anatomical locations of human skin: comparative assessment with two different Raman spectroscopy methods","volume":"18","author":"Darvin","year":"2009","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0090","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1600-0625.2010.01191.x","article-title":"Topical beta-carotene protects against infra-red-light-induced free radicals","volume":"20","author":"Darvin","year":"2011","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0095","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jdermsci.2011.06.009","article-title":"Dermal carotenoid level and kinetics after topical and systemic administration of antioxidants: enrichment strategies in a controlled in vivo study","volume":"64","author":"Darvin","year":"2011","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0100","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1134\/S1054660X06050148","article-title":"In vivo Raman spectroscopic analysis of the influence of UV radiation on carotenoid antioxidant substance degradation of the human skin","volume":"16","author":"Darvin","year":"2006","journal-title":"Laser Phys."},{"key":"10.1016\/j.arr.2014.03.006_bib0105","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/lapl.200610113","article-title":"In vivo Raman spectroscopic analysis of the influence of IR radiation on the carotenoid antioxidant substances beta-carotene and lycopene in the human skin","volume":"4","author":"Darvin","year":"2007","journal-title":"Formation of free radicals. Laser Phys Lett"},{"key":"10.1016\/j.arr.2014.03.006_bib0110","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1159\/000257262","article-title":"Radical production by infrared A irradiation in human tissue","volume":"23","author":"Darvin","year":"2010","journal-title":"Skin Pharmacol. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0115","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/jid.2009.283","article-title":"Formation of free radicals in human skin during irradiation with infrared light","volume":"130","author":"Darvin","year":"2010","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0120","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/jbio.200900111","article-title":"Determination of the influence of IR radiation on the antioxidative network of the human skin","volume":"4","author":"Darvin","year":"2011","journal-title":"J. Biophotonics"},{"key":"10.1016\/j.arr.2014.03.006_bib0125","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1159\/000338976","article-title":"Safety assessment by multiphoton fluorescence\/second harmonic generation\/hyper-Rayleigh scattering tomography of ZnO nanoparticles used in cosmetic products","volume":"25","author":"Darvin","year":"2012","journal-title":"Skin Pharmacol. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0130","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/lapl.200810124","article-title":"Influence of two different IR radiators on the antioxidative potential of the human skin","volume":"6","author":"Darvin","year":"2009","journal-title":"Laser Phys. Lett."},{"key":"10.1016\/j.arr.2014.03.006_bib0135","doi-asserted-by":"crossref","first-page":"10491","DOI":"10.3390\/molecules161210491","article-title":"The role of carotenoids in human skin","volume":"16","author":"Darvin","year":"2011","journal-title":"Molecules"},{"key":"10.1016\/j.arr.2014.03.006_bib0140","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1134\/S0030400X09120133","article-title":"Influence of IR radiation on the carotenoid content in human skin","volume":"107","author":"Darvin","year":"2009","journal-title":"Opt. Spectrosc."},{"key":"10.1016\/j.arr.2014.03.006_bib0145","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1111\/j.1751-1097.2011.00968.x","article-title":"Low-level laser therapy improves skeletal muscle performance, decreases skeletal muscle damage and modulates mRNA expression of COX-1 and COX-2 in a dose-dependent manner","volume":"87","author":"de Almeida","year":"2011","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0150","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1001\/archderm.135.5.608","article-title":"Effects on human epidermis of chronic suberythemal exposure to pure infrared radiation","volume":"135","author":"Edwards","year":"1999","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0155","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s10103-010-0855-0","article-title":"Effects of low level laser therapy (808nm) on physical strength training in humans","volume":"26","author":"Ferraresi","year":"2011","journal-title":"Laser Med. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0160","doi-asserted-by":"crossref","first-page":"035002","DOI":"10.1117\/1.3555183","article-title":"Kinetics of carotenoid distribution in human skin in vivo after exogenous stress: disinfectant and wIRA-induced carotenoid depletion recovers from outside to inside","volume":"16","author":"Fluhr","year":"2011","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.arr.2014.03.006_bib0165","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1038\/nrm3479","article-title":"Mitochondria: master regulators of danger signalling","volume":"13","author":"Galluzzi","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.arr.2014.03.006_bib0170","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/lsm.20635","article-title":"Irradiation with 780nm diode laser attenuates inflammatory cytokines but upregulates nitric oxide in lipopolysaccharide-stimulated macrophages: implications for the prevention of aneurysm progression","volume":"40","author":"Gavish","year":"2008","journal-title":"Lasers Surg. Med."},{"key":"10.1016\/j.arr.2014.03.006_bib0175","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.bbadis.2004.11.015","article-title":"Carotenoids as modulators of lipid membrane physical properties","volume":"1740","author":"Gruszecki","year":"2005","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.arr.2014.03.006_bib0180","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1600-0625.2010.01246.x","article-title":"Determination of the antioxidative capacity of the skin in vivo using resonance Raman and electron paramagnetic resonance spectroscopy","volume":"20","author":"Haag","year":"2011","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0185","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ejpb.2013.06.016","article-title":"Enhancement of skin radical scavenging activity and stratum corneum lipids after the application of a hyperforin-rich cream","volume":"86","author":"Haag","year":"2014","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.arr.2014.03.006_bib0190","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0304-3959(00)00353-5","article-title":"Cloning and functional expression of a human orthologue of rat vanilloid receptor-1","volume":"88","author":"Hayes","year":"2000","journal-title":"Pain"},{"key":"10.1016\/j.arr.2014.03.006_bib0195","first-page":"223","article-title":"Low-level laser therapy facilitates superficial wound healing in humans: a triple-blind, sham-controlled study","volume":"39","author":"Hopkins","year":"2004","journal-title":"J. Athl. Train."},{"key":"10.1016\/j.arr.2014.03.006_bib0200","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1038\/sj.jid.5700666","article-title":"Human epidermal keratinocytes accumulate superoxide due to low activity of Mn-SOD, leading to mitochondrial functional impairment","volume":"127","author":"Hornig-Do","year":"2007","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0205","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1744-8069-7-37","article-title":"TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation","volume":"7","author":"Huang","year":"2011","journal-title":"Mol. Pain"},{"key":"10.1016\/j.arr.2014.03.006_bib0210","doi-asserted-by":"crossref","first-page":"358","DOI":"10.2203\/dose-response.09-027.Hamblin","article-title":"Biphasic dose response in low level light therapy","volume":"7","author":"Huang","year":"2009","journal-title":"Dose-Response"},{"key":"10.1016\/j.arr.2014.03.006_bib0215","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/biof.5520200103","article-title":"Oxidation of carotenoids by heat and tobacco smoke","volume":"20","author":"Hurst","year":"2004","journal-title":"Biofactors"},{"key":"10.1016\/j.arr.2014.03.006_bib0220","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s12032-007-9020-4","article-title":"The effects inhibiting the proliferation of cancer cells by far-infrared radiation (FIR) are controlled by the basal expression level of heat shock protein (HSP) 70A","volume":"25","author":"Ishibashi","year":"2008","journal-title":"Med. Oncol."},{"key":"10.1016\/j.arr.2014.03.006_bib0225","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1038\/jid.2008.362","article-title":"Infrared radiation confers resistance to UV-induced apoptosis via reduction of DNA damage and upregulation of antiapoptotic proteins","volume":"129","author":"Jantschitsch","year":"2009","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0230","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.freeradbiomed.2009.10.036","article-title":"Effects of water-filtered infrared A irradiation on human fibroblasts","volume":"48","author":"Jung","year":"2010","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.arr.2014.03.006_bib0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1011-1344(98)00219-X","article-title":"Primary and secondary mechanisms of action of visible to near-IR radiation on cells","volume":"49","author":"Karu","year":"1999","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.arr.2014.03.006_bib0240","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1111\/j.1751-1097.2008.00394.x","article-title":"Mitochondrial signaling in mammalian cells activated by red and near-IR radiation","volume":"84","author":"Karu","year":"2008","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0245","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1089\/pho.2005.23.355","article-title":"Exact action spectra for cellular responses relevant to phototherapy","volume":"23","author":"Karu","year":"2005","journal-title":"Photomed. Laser Surg."},{"key":"10.1016\/j.arr.2014.03.006_bib0250","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.mad.2006.09.007","article-title":"Regulation of type I procollagen and MMP-1 expression after single or repeated exposure to infrared radiation in human skin","volume":"127","author":"Kim","year":"2006","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.arr.2014.03.006_bib0255","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1365-2133.2008.08838.x","article-title":"Acute exposure of human skin to ultraviolet or infrared radiation or heat stimuli increases mast cell numbers and tryptase expression in human skin in vivo","volume":"160","author":"Kim","year":"2009","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0260","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000330721","article-title":"Full-body skin mapping for six biophysical parameters: baseline values at 16 anatomical sites in 125 human subjects","volume":"25","author":"Kleesz","year":"2012","journal-title":"Skin Pharmacol. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0265","series-title":"Dermatology in General Medicine","first-page":"220","article-title":"Photophysics, photochemistry, and phobiology","author":"Kochevar","year":"1999"},{"key":"10.1016\/j.arr.2014.03.006_bib0270","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1038\/jid.2012.148","article-title":"How much sun protection is needed?: are we on the way to full-spectrum protection","volume":"132","author":"Kolbe","year":"2012","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0275","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0899-9007(01)00651-7","article-title":"Carotenoids as antioxidants","volume":"17","author":"Krinsky","year":"2001","journal-title":"Nutrition"},{"key":"10.1016\/j.arr.2014.03.006_bib0280","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/jid.2011.394","article-title":"Sun exposure: what molecular photodermatology tells us about its good and bad sides","volume":"132","author":"Krutmann","year":"2012","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0285","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/jidsymp.2009.1","article-title":"Role of mitochondria in photoaging of human skin: the defective powerhouse model","volume":"14","author":"Krutmann","year":"2009","journal-title":"J. Invest. Dermatol. Symp. Proc."},{"key":"10.1016\/j.arr.2014.03.006_bib0290","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1002\/lapl.200810092","article-title":"In vivo Raman spectroscopy detects increased epidermal antioxidative potential with topically applied carotenoids","volume":"6","author":"Lademann","year":"2009","journal-title":"Laser Phys. Lett."},{"key":"10.1016\/j.arr.2014.03.006_bib0295","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1159\/000328725","article-title":"Uptake of antioxidants by natural nutrition and supplementation: pros and cons from the dermatological point of view","volume":"24","author":"Lademann","year":"2011","journal-title":"Skin Pharmacol. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0300","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jdermsci.2013.07.015","article-title":"Solar-simulated radiation and heat treatment induced metalloproteinase-1 expression in cultured dermal fibroblasts via distinct pathways: implications on reduction of sun-associated aging","volume":"72","author":"Lan","year":"2013","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0305","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1007\/s00421-009-1321-1","article-title":"Effect of low-level laser therapy (GaAs 904nm) in skeletal muscle fatigue and biochemical markers of muscle damage in rats","volume":"108","author":"Leal Junior","year":"2010","journal-title":"Eur. J. Appl. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0310","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/j.1600-0781.2006.00201.x","article-title":"Minimal heating dose: a novel biological unit to measure infrared irradiation","volume":"22","author":"Lee","year":"2006","journal-title":"Photodermatol. Photoimmunol. Photomed."},{"key":"10.1016\/j.arr.2014.03.006_bib0315","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1111\/j.1600-0625.2008.00738.x","article-title":"Heat-induced MMP-1 expression is mediated by TRPV1 through PKCalpha signaling in HaCaT cells","volume":"17","author":"Lee","year":"2008","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0320","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1038\/sj.jid.5700880","article-title":"Transient receptor potential vanilloid-1 mediates heat-shock-induced matrix metalloproteinase-1 expression in human epidermal keratinocytes","volume":"127","author":"Li","year":"2007","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0325","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1038\/jid.2011.476","article-title":"Irradiation of skin with visible light induces reactive oxygen species and matrix-degrading enzymes","volume":"132","author":"Liebel","year":"2012","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0330","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/(SICI)1096-9101(1997)21:5<493::AID-LSM12>3.0.CO;2-A","article-title":"Changes in calcium transport in mammalian sperm mitochondria and plasma membranes caused by 780nm irradiation","volume":"21","author":"Lubart","year":"1997","journal-title":"Laser Surg. Med."},{"key":"10.1016\/j.arr.2014.03.006_bib0335","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1038\/nrm3434","article-title":"TGFbeta signalling in context","volume":"13","author":"Massague","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.arr.2014.03.006_bib0340","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jdermsci.2010.07.005","article-title":"Wavelength dependency for UVA-induced suppression of recall immunity in humans","volume":"59","author":"Matthews","year":"2010","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0345","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/j.1751-1097.2010.00838.x","article-title":"Radical protection by sunscreens in the infrared spectral range","volume":"87","author":"Meinke","year":"2011","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0350","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1111\/php.12137","article-title":"Radical protection by differently composed creams in the UV\/VIS and IR spectral ranges","volume":"89","author":"Meinke","year":"2013","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0355","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1093\/toxsci\/kfr148","article-title":"Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin: an in vitro and in vivo study","volume":"123","author":"Monteiro-Riviere","year":"2011","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0360","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1111\/j.1751-1097.2011.00969.x","article-title":"The consequences of UV-induced immunosuppression for human health","volume":"87","author":"Norval","year":"2011","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0365","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1159\/000101807","article-title":"Beneficial long-term effects of combined oral\/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study","volume":"20","author":"Palombo","year":"2007","journal-title":"Skin Pharmacol. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0370","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/0076-6879(92)13142-K","article-title":"Antioxidant effects of carotenoids in vivo and in vitro: an overview","volume":"213","author":"Palozza","year":"1992","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.arr.2014.03.006_bib0375","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1111\/j.0022-202X.2004.23487.x","article-title":"Heat shock-induced matrix metalloproteinase (MMP)-1 and MMP-3 are mediated through ERK and JNK activation and via an autocrine interleukin-6 loop","volume":"123","author":"Park","year":"2004","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0380","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/nrn1141","article-title":"ThermoTRP channels and beyond: mechanisms of temperature sensation","volume":"4","author":"Patapoutian","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.arr.2014.03.006_bib0385","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1126\/science.1073140","article-title":"A heat-sensitive TRP channel expressed in keratinocytes","volume":"296","author":"Peier","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.arr.2014.03.006_bib0390","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/j.1751-1097.2010.00729.x","article-title":"Effects of infrared-A irradiation on skin: discrepancies in published data highlight the need for an exact consideration of physical and photobiological laws and appropriate experimental settings","volume":"86","author":"Piazena","year":"2010","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0395","first-page":"171","article-title":"Effects of infrared and UVA rays on the human skin and their efficacy in the treatment of atopic dermatitis","volume":"60","author":"Pullmann","year":"1985","journal-title":"Z. Hautkr."},{"key":"10.1016\/j.arr.2014.03.006_bib0400","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jphotobiol.2007.02.005","article-title":"Effects of a single near-infrared laser treatment on cutaneous wound healing: biometrical and histological study in rats","volume":"87","author":"Rezende","year":"2007","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.arr.2014.03.006_bib0405","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1600-0625.2012.01438.x","article-title":"Dermal mast cells affect the development of sunlight-induced skin tumours","volume":"21","author":"Sarchio","year":"2012","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0410","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1039\/b418378a","article-title":"Ultraviolet B radiation-induced immunosuppression: molecular mechanisms and cellular alterations","volume":"4","author":"Schade","year":"2005","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0415","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1046\/j.1523-1747.2002.19630.x","article-title":"Infrared-A radiation-induced matrix metalloproteinase 1 expression is mediated through extracellular signal-regulated kinase 1\/2 activation in human dermal fibroblasts","volume":"119","author":"Schieke","year":"2002","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0420","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1034\/j.1600-0781.2003.00054.x","article-title":"Cutaneous effects of infrared radiation: from clinical observations to molecular response mechanisms","volume":"19","author":"Schieke","year":"2003","journal-title":"Photodermatol. Photoimmunol. Photomed."},{"key":"10.1016\/j.arr.2014.03.006_bib0425","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1159\/000018140","article-title":"Diabetic neuropathic foot ulcer: successful treatment by low-intensity laser therapy","volume":"198","author":"Schindl","year":"1999","journal-title":"Dermatology"},{"key":"10.1016\/j.arr.2014.03.006_bib0430","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1159\/000257259","article-title":"Photoprotection beyond ultraviolet radiation\u2014effective sun protection has to include protection against infrared A radiation-induced skin damage","volume":"23","author":"Schroeder","year":"2010","journal-title":"Skin Pharmacol. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0435","first-page":"4","article-title":"Prevention of infrared-A radiation mediated detrimental effects in human skin","volume":"14","author":"Schroeder","year":"2009","journal-title":"Skin Therapy Lett."},{"key":"10.1016\/j.arr.2014.03.006_bib0440","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1038\/jid.2008.116","article-title":"Infrared radiation-induced matrix metalloproteinase in human skin: implications for protection","volume":"128","author":"Schroeder","year":"2008","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0445","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.freeradbiomed.2007.04.002","article-title":"Cellular response to infrared radiation involves retrograde mitochondrial signaling","volume":"43","author":"Schroeder","year":"2007","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.arr.2014.03.006_bib0450","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.freeradbiomed.2007.10.053","article-title":"Reactive oxygen species produced by NADPH oxidase, xanthine oxidase, and mitochondrial electron transport system mediate heat shock-induced MMP-1 and MMP-9 expression","volume":"44","author":"Shin","year":"2008","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.arr.2014.03.006_bib0455","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1039\/C2PP25152C","article-title":"Effects of ultraviolet radiation, visible light, and infrared radiation on erythema and pigmentation: a review","volume":"12","author":"Sklar","year":"2013","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0460","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nature00894","article-title":"TRPV3 is a temperature-sensitive vanilloid receptor-like protein","volume":"418","author":"Smith","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.arr.2014.03.006_bib0465","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1089\/1549541041438560","article-title":"Alteration of skin temperature during low-level laser irradiation at 830nm in a mouse model","volume":"22","author":"Stadler","year":"2004","journal-title":"Photomed. Laser Surg."},{"key":"10.1016\/j.arr.2014.03.006_bib0470","first-page":"e12","article-title":"Near-infrared irradiation non-thermally affects subcutaneous adipocytes and bones","volume":"11","author":"Tanaka","year":"2011","journal-title":"Eplasty"},{"key":"10.1016\/j.arr.2014.03.006_bib0475","first-page":"e22","article-title":"Near-infrared irradiation nonthermally induces long-lasting vasodilation by causing apoptosis of vascular smooth muscle cells","volume":"11","author":"Tanaka","year":"2011","journal-title":"Eplasty"},{"key":"10.1016\/j.arr.2014.03.006_bib0480","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1111\/j.1349-7006.2010.01548.x","article-title":"Non-thermal cytocidal effect of infrared irradiation on cultured cancer cells using specialized device","volume":"101","author":"Tanaka","year":"2010","journal-title":"Cancer Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0485","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1177\/153537020322800612","article-title":"Promotive effects of far-infrared ray on full-thickness skin wound healing in rats","volume":"228","author":"Toyokawa","year":"2003","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.arr.2014.03.006_bib0490","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1515\/plm-2012-0034","article-title":"Far infrared radiation (FIR): its biological effects and medical applications","volume":"1","author":"Vatansever","year":"2012","journal-title":"Photon. Lasers Med."},{"key":"10.1016\/j.arr.2014.03.006_bib0495","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1038\/jid.2010.433","article-title":"ROS quenching potential of the epidermal cornified cell envelope","volume":"131","author":"Vermeij","year":"2011","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.arr.2014.03.006_bib0500","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s10103-011-0984-0","article-title":"Effects of low-level laser therapy (808nm) on isokinetic muscle performance of young women submitted to endurance training: a randomized controlled clinical trial","volume":"27","author":"Vieira","year":"2012","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0505","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1007\/s00421-011-2296-2","article-title":"The influence of endurance exercise on the antioxidative status of human skin","volume":"112","author":"Vierck","year":"2012","journal-title":"Eur. J. Appl. Physiol."},{"key":"10.1016\/j.arr.2014.03.006_bib0510","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s10103-003-0262-x","article-title":"Increased fibroblast proliferation induced by light emitting diode and low power laser irradiation","volume":"18","author":"Vinck","year":"2003","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.arr.2014.03.006_bib0515","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1002\/lsm.20766","article-title":"Low level light effects on inflammatory cytokine production by rheumatoid arthritis synoviocytes","volume":"41","author":"Yamaura","year":"2009","journal-title":"Lasers Surg. Med."},{"key":"10.1016\/j.arr.2014.03.006_bib0520","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1600-0781.2006.00208.x","article-title":"Biological effect of far-infrared therapy on increasing skin microcirculation in rats","volume":"22","author":"Yu","year":"2006","journal-title":"Photodermatol. Photoimmunol. Photomed."},{"key":"10.1016\/j.arr.2014.03.006_bib0525","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000188083","article-title":"The missing link\u2014light-induced (280\u20131,600nm) free radical formation in human skin","volume":"22","author":"Zastrow","year":"2009","journal-title":"Skin Pharmacol. Physiol."}],"container-title":["Ageing Research Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568163714000439?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568163714000439?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T11:17:07Z","timestamp":1565349427000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568163714000439"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":105,"alternative-id":["S1568163714000439"],"URL":"https:\/\/doi.org\/10.1016\/j.arr.2014.03.006","relation":{},"ISSN":["1568-1637"],"issn-type":[{"value":"1568-1637","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular action mechanisms of solar infrared radiation and heat on human skin","name":"articletitle","label":"Article Title"},{"value":"Ageing Research Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arr.2014.03.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}