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Res."},{"key":"10.1016\/j.arr.2023.101960_bib73","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1016\/j.phytochem.2006.07.014","article-title":"Phytochemical and genetic analysis in selected chemotypes of Withania somnifera","volume":"67","author":"Dhar","year":"2006","journal-title":"Phytochem"},{"key":"10.1016\/j.arr.2023.101960_bib74","first-page":"262","article-title":"Screening for antidepressant-like activity of Convolvulus pluricaulis Choisy in mice","volume":"1","author":"Dhingra","year":"2007","journal-title":"Pharmacol. Online"},{"key":"10.1016\/j.arr.2023.101960_bib75","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4236\/aad.2016.51001","article-title":"Psychophysiological effects of Sideritis and Bacopa extract and three combinations thereof\u2014a quantitative EEG study in subjects suffering from mild cognitive impairment (MCI)","volume":"5","author":"Dimpfel","year":"2016","journal-title":"Adv. Alzheimer'S. Dis."},{"key":"10.1016\/j.arr.2023.101960_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113208","article-title":"Signal pathways in the treatment of Alzheimer\u2019s disease with traditional Chinese medicine","volume":"152","author":"Ding","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.arr.2023.101960_bib77","doi-asserted-by":"crossref","first-page":"988","DOI":"10.3390\/biom10070988","article-title":"Bioactive natural compounds and antioxidant activity of essential oils from spice plants: new findings and potential applications","volume":"10","author":"Diniz do Nascimento","year":"2020","journal-title":"Biomolecules"},{"key":"10.1016\/j.arr.2023.101960_bib78","doi-asserted-by":"crossref","first-page":"847e","DOI":"10.1097\/PRS.0000000000006661","article-title":"Protective effect of extract of Ginkgo biloba 761 against frostbite injury in rats","volume":"145","author":"Dong","year":"2020","journal-title":"Plast., Reconstr. Surg."},{"key":"10.1016\/j.arr.2023.101960_bib79","doi-asserted-by":"crossref","first-page":"104516","DOI":"10.1016\/j.fitote.2020.104516","article-title":"A new bilobalide isomer and two cis-coumaroylatedflavonol glycosides from Ginkgo biloba leaves","volume":"142","author":"Dong","year":"2020","journal-title":"Fitoterapia"},{"key":"10.1016\/j.arr.2023.101960_bib80","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1111\/jphp.12398","article-title":"Withania somnifera (Ashwagandha) in neurobehavioural disorders induced by brain oxidative stress in rodents: a systematic review and meta-analysis","volume":"67","author":"Durg","year":"2015","journal-title":"J. Pharm. Pharm."},{"key":"10.1016\/j.arr.2023.101960_bib81","doi-asserted-by":"crossref","first-page":"162","DOI":"10.4103\/epj.epj_63_19","article-title":"Mechanism of action and bioactivities of Cinnamomum zeylanicum essential oil against some pathogenic microbes","volume":"19","author":"Elgammal","year":"2020","journal-title":"Egypt Pharm. J."},{"key":"10.1016\/j.arr.2023.101960_bib82","first-page":"1","article-title":"Cinnamon (Cinnamomum zeylanicum) oil as a potential alternative to antibiotics in poultry","volume":"9","author":"El-Hack","year":"2020","journal-title":"Antibiotics"},{"key":"10.1016\/j.arr.2023.101960_bib83","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1081\/JLC-100101744","article-title":"High-performance liquid chromatography and thin-layer chromatography of phenolic acids from Ginkgo biloba L. leaves collected within vegetative period","volume":"22","author":"Ellnain-Wojtaszek","year":"1999","journal-title":"J. Liq. Chromatogr. Relat. Technol."},{"key":"10.1016\/j.arr.2023.101960_bib84","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/mrc.3936","article-title":"Utilizing NMR and EPR spectroscopy to probe the role of copper in prion diseases","volume":"51","author":"Emwas","year":"2013","journal-title":"Magn. Reson. Chem."},{"key":"10.1016\/j.arr.2023.101960_bib85","doi-asserted-by":"crossref","first-page":"101391","DOI":"10.1016\/j.arr.2021.101391","article-title":"Living with the enemy: From protein-misfolding pathologies we know, to those we want to know","volume":"70","author":"Emwas","year":"2021","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.arr.2023.101960_bib86","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1007\/s12035-015-9108-3","article-title":"A new perspective of lysosomal cation channel-dependent homeostasis in Alzheimer\u2019s disease","volume":"53","author":"Ezeani","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.arr.2023.101960_bib87","first-page":"1","article-title":"Moringa oleifera: a Review of the medical evidence for its nutritional, therapeutic, and prophylactic properties","volume":"1","author":"Fahey","year":"2005","journal-title":"Part 1. Trees Life J."},{"key":"10.1016\/j.arr.2023.101960_bib88","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1055\/s-2006-957414","article-title":"Hypotensive constituents from the pods of Moringa oleifera","volume":"64","author":"Faizi","year":"1998","journal-title":"Planta Med"},{"key":"10.1016\/j.arr.2023.101960_bib89","doi-asserted-by":"crossref","first-page":"15910","DOI":"10.1002\/chem.201202697","article-title":"A bioinorganic view of Alzheimer\u2019s disease: When misplaced metal ions (Re)direct the electrons to the wrong target","volume":"18","author":"Faller","year":"2012","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.arr.2023.101960_bib90","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/hup.2412","article-title":"Comparing the efficacy and safety of Crocus sativus L. with memantine in patients with moderate to severe Alzheimer's disease: a double\u2010blind randomized clinical trial","volume":"29","author":"Farokhnia","year":"2014","journal-title":"Hum. Psychopharmacol."},{"key":"10.1016\/j.arr.2023.101960_bib91","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.phrs.2009.02.012","article-title":"Ginkgo biloba extract (EGb761) influences monoaminergic neurotransmission via inhibition of NE uptake, but not MAO activity after chronic treatment","volume":"60","author":"Fehske","year":"2009","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.arr.2023.101960_bib92","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.mcn.2019.06.009","article-title":"Mitochondrial dynamics and transport in Alzheimer\u2019s disease","volume":"98","author":"Flannery","year":"2019","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.arr.2023.101960_bib93","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1515\/znc-2006-11-1209","article-title":"Binding of an oxindole alkaloid from Uncaria tomentosa to amyloid protein (A\u03b21-40)","volume":"61","author":"Fr\u0105ckowiak","year":"2006","journal-title":"Z. Naturforsch. C."},{"key":"10.1016\/j.arr.2023.101960_bib94","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.4315\/0362-028X-66.10.1811","article-title":"Antibacterial activities of phenolic benzaldehydes and benzoic acids against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella enterica","volume":"66","author":"Friedman","year":"2003","journal-title":"J. Food Prot."},{"key":"10.1016\/j.arr.2023.101960_bib95","first-page":"121","article-title":"Protective role of an Indian herb, Moringa oleifera in memory impairment by high altitude hypoxic exposure: possible role of monoamines","volume":"20","author":"Ganguly","year":"2006","journal-title":"Biog. Amines"},{"key":"10.1016\/j.arr.2023.101960_bib96","first-page":"744","article-title":"Alteration of brain monoamines and EEG wave pattern in rat model of Alzheimer\u2019s disease and protection by Moringa oleifera","volume":"128","author":"Ganguly","year":"2008","journal-title":"Indian J. Med. Res."},{"key":"10.1016\/j.arr.2023.101960_bib97","doi-asserted-by":"crossref","first-page":"108","DOI":"10.4103\/2231-4040.111527","article-title":"Development of polyherbal antidiabetic formulation encapsulated in the phospholipids vesicle system","volume":"4","author":"Gauttam","year":"2013","journal-title":"J. Adv. Pharm. Technol. Res"},{"key":"10.1016\/j.arr.2023.101960_bib98","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3233\/JAD-122113","article-title":"Interaction of cinnamaldehyde and epicatechin with tau: implications of beneficial effects in modulating Alzheimer's disease pathogenesis","volume":"36","author":"George","year":"2013","journal-title":"J. Alzheimer'S. Dis."},{"key":"10.1016\/j.arr.2023.101960_bib99","doi-asserted-by":"crossref","first-page":"6131","DOI":"10.1021\/jf300589c","article-title":"Saffron as a source of novel acetylcholinesterase inhibitors: molecular docking and in vitro enzymatic studies","volume":"60","author":"Geromichalos","year":"2012","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.arr.2023.101960_bib100","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ejphar.2011.05.012","article-title":"Protective effects of saffron extract and its active constituent crocin against oxidative stress and spatial learning and memory deficits induced by chronic stress in rats","volume":"667","author":"Ghadrdoost","year":"2011","journal-title":"Eur. J. Pharm."},{"key":"10.1016\/j.arr.2023.101960_bib101","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1126\/science.1132814","article-title":"A century of Alzheimer\u2019s disease","volume":"314","author":"Goedert","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.arr.2023.101960_bib102","first-page":"8473","article-title":"Cell culture study on the effects of \u201ccureit\u201d - a novel bio available curcumin on hyaluronidase inhibition e anti-aging effects","volume":"6","author":"Gopi","year":"2014","journal-title":"Int. J. Curr. Res."},{"key":"10.1016\/j.arr.2023.101960_bib103","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S1474-4422(18)30028-0","article-title":"Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer\u2019s disease: a longitudinal study","volume":"17","author":"Gordon","year":"2018","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.arr.2023.101960_bib104","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1055\/s-2007-981521","article-title":"A bioactive polyacetylene compound isolated from Centella asiatica","volume":"73","author":"Govindan","year":"2007","journal-title":"Planta Med."},{"key":"10.1016\/j.arr.2023.101960_bib105","doi-asserted-by":"crossref","first-page":"5969","DOI":"10.1021\/jf047989j","article-title":"Effect of drying temperature and air flow on the production and retention of secondary metabolites in saffron","volume":"53","author":"Gregory","year":"2005","journal-title":"J. Agric. 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Ethnopharmacol."},{"key":"10.1016\/j.arr.2023.101960_bib112","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1046\/j.1460-9568.2000.00164.x","article-title":"\u03b2-Amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis","volume":"12","author":"Harkany","year":"2000","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.arr.2023.101960_bib113","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40780-015-0014-7","article-title":"Meta-analysis of the efficacy and safety of Ginkgo biloba extract for the treatment of dementia","volume":"1","author":"Hashiguchi","year":"2015","journal-title":"J. Pharm. 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J."},{"key":"10.1016\/j.arr.2023.101960_bib121","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3892\/br.2016.630","article-title":"Role of oxidative stress in Alzheimer\u2019s disease (review)","volume":"4","author":"Huang","year":"2016","journal-title":"Biomed. Rep."},{"key":"10.1016\/j.arr.2023.101960_bib122","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.euroneuro.2009.02.002","article-title":"Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT)","volume":"19","author":"Ishrat","year":"2009","journal-title":"Eur. 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Chromatogr."},{"key":"10.1016\/j.arr.2023.101960_bib125","doi-asserted-by":"crossref","first-page":"7661","DOI":"10.1007\/s00253-014-5955-5","article-title":"Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals","volume":"98","author":"Jiang","year":"2014","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.arr.2023.101960_bib126","first-page":"100030","article-title":"Phytotherapy: a promising approach for the treatment of Alzheimer\u2019s disease","volume":"2","author":"John","year":"2022","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.arr.2023.101960_bib127","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/pca.823","article-title":"Chemical identification of the sources of commercial Fructus Chebulae","volume":"16","author":"Juang","year":"2005","journal-title":"Phytochem. 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Med"},{"key":"10.1016\/j.arr.2023.101960_bib286","doi-asserted-by":"crossref","first-page":"184","DOI":"10.2174\/1871527319666200526144141","article-title":"The \u03b2-Secretase enzyme BACE1: a biochemical enigma for Alzheimer\u2019s disease","volume":"19","author":"Shah","year":"2020","journal-title":"CNS Neurol. Disord. Drug Targets"},{"key":"10.1016\/j.arr.2023.101960_bib287","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.indcrop.2017.12.013","article-title":"Elucidation of micromolecular phenylpropanoid and lignan glycosides as the main antioxidants of Ginkgo seeds","volume":"112","author":"Shan","year":"2018","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.arr.2023.101960_bib288","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/1750-1326-4-48","article-title":"Alzheimer\u2019s disease: synaptic dysfunction and A\u03b2","volume":"4","author":"Shankar","year":"2009","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.arr.2023.101960_bib289","first-page":"1479","article-title":"Cholinesterase inhibitors as Alzheimer\u2019s therapeutics (review)","volume":"25","author":"Sharma","year":"2019","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.arr.2023.101960_bib290","first-page":"479","article-title":"Effect of Convolvulus pluricaulis Choisy and Asparagus racemosus Wild on learning and memory in young and old mice: A comparative evaluation","volume":"48","author":"Sharma","year":"2010","journal-title":"Indian J. Exp. Biol."},{"key":"10.1016\/j.arr.2023.101960_bib291","first-page":"260","article-title":"Hepatoprotective effects of Ginkgo biloba against carbon tetrachloride induced hepatic injury in rats","volume":"33","author":"Shenoy","year":"2001","journal-title":"Indian J. Pharm."},{"key":"10.1016\/j.arr.2023.101960_bib292","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.3390\/molecules27072143","article-title":"Prokinetic and laxative effects of Chrozophora tinctoria whole plant extract","volume":"27","author":"Sher","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.arr.2023.101960_bib293","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s11418-019-01359-8","article-title":"Chemical constituents from Ginkgo biloba leaves and their cytotoxicity activity","volume":"74","author":"Shu","year":"2020","journal-title":"J. Nat. Med"},{"key":"10.1016\/j.arr.2023.101960_bib294","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1021\/jf020444+","article-title":"Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves","volume":"51","author":"Siddhuraju","year":"2003","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.arr.2023.101960_bib295","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1080\/10286020600782454","article-title":"Chemical constituents of Centella asiatica","volume":"9","author":"Siddiqui","year":"2007","journal-title":"J. Asian Nat. Prod. Res."},{"key":"10.1016\/j.arr.2023.101960_bib296","first-page":"159","article-title":"Moringa oleifera Leaf extract prevents in vitro oxidative DNA damage","volume":"6","author":"Sidker","year":"2013","journal-title":"Asian J. Pharm. Clin. Res"},{"key":"10.1016\/j.arr.2023.101960_bib297","first-page":"473","article-title":"Evaluation of antimicrobial efficacy of flavonoids of Withania somnifera L","volume":"73","author":"Singh","year":"2011","journal-title":"Indian J. Pharm. Sci."},{"key":"10.1016\/j.arr.2023.101960_bib298","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1017\/jns.2017.48","article-title":"In vitro screening of neuroprotective activity of Indian medicinal plant Withania somnifera","volume":"6","author":"Singh","year":"2017","journal-title":"J. Nut. Sci."},{"key":"10.1016\/j.arr.2023.101960_bib299","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s10522-008-9185-z","article-title":"Neuronutrient impact of ayurvedic rasayana therapy in brain aging","volume":"9","author":"Singh","year":"2008","journal-title":"Biogerontology"},{"key":"10.1016\/j.arr.2023.101960_bib300","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1016\/j.chemosphere.2005.07.030","article-title":"Effect of iron on lipid peroxidation, and enzymatic and non-enzymatic antioxidants and bacoside-A content in medicinal plant Bacopa monnieri L","volume":"62","author":"Sinha","year":"2006","journal-title":"Chemosphere"},{"key":"10.1016\/j.arr.2023.101960_bib301","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S1050-4648(02)00140-7","article-title":"Immunostimulation in crsustaceans: does it really protect against infection?","volume":"15","author":"Smith","year":"2003","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.arr.2023.101960_bib302","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-38645-0","article-title":"The Amazon rain forest plant Uncaria tomentosa (cat\u2019s claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles","volume":"9","author":"Snow","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.arr.2023.101960_bib303","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1007\/s12035-018-1188-4","article-title":"The gut microbiome alterations and inflammation-driven pathogenesis of Alzheimer\u2019s disease\u2014a critical review","volume":"56","author":"Sochocka","year":"2019","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.arr.2023.101960_bib304","doi-asserted-by":"crossref","first-page":"595","DOI":"10.4236\/health.2010.26088","article-title":"Inhibition of H2O2-induced DNA damage in single cell gel electrophoresis assay (comet assay) by castasterone isolated from leaves of Centella asiatica","volume":"2","author":"Sondhi","year":"2010","journal-title":"Health"},{"key":"10.1016\/j.arr.2023.101960_bib305","doi-asserted-by":"crossref","unstructured":"Soria Lopez, J.A., Gonzalez, H.M., Leger, G.C. 2019. Alzheimer\u2019s disease. In: Handbook of Clin. Neurol. 231\u2013255. doi: 10.1016\/B978\u20130-12\u2013804766-8.00013\u20133.","DOI":"10.1016\/B978-0-12-804766-8.00013-3"},{"key":"10.1016\/j.arr.2023.101960_bib306","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1211\/jpp.57.9.0018","article-title":"Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in\u2010vitro","volume":"57","author":"Soumyanath","year":"2005","journal-title":"J. Pharm. Pharm."},{"key":"10.1016\/j.arr.2023.101960_bib307","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.788312","article-title":"Centella asiatica alters metabolic pathways associated with Alzheimer\u2019s disease in the 5xFAD Mouse Model of \u03b2-Amyloid Accumulation","author":"Speers","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.arr.2023.101960_bib308","first-page":"233","article-title":"Some chemical constituents from Centella asiatica","volume":"33","author":"Srivastava","year":"1996","journal-title":"Indian Drugs"},{"key":"10.1016\/j.arr.2023.101960_bib309","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/jppr.1560","article-title":"Rhabdomyolysis after Ginkgo biloba and cannabis","volume":"49","author":"Strain","year":"2019","journal-title":"J. Pharm. Pract. Res"},{"key":"10.1016\/j.arr.2023.101960_bib310","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s11418-008-0229-0","article-title":"Two new flavonoids from Centella asiatica (Linn.)","volume":"62","author":"Subban","year":"2008","journal-title":"J. Nat. Med."},{"key":"10.1016\/j.arr.2023.101960_bib311","first-page":"133","article-title":"Immunomodulatory activity of methanolic leaf extract of Moringa oleifera in animals","volume":"54","author":"Sudha","year":"2010","journal-title":"Indian J. Physiol. Pharmacol."},{"key":"10.1016\/j.arr.2023.101960_bib312","first-page":"310","article-title":"Isolation and characterization of glycosides from Convolvulus prostratus, Ficus virens, Phoenix dactifera, Spondias mangifera and Terminalia belerica","volume":"5","author":"Sultana","year":"2018","journal-title":"Eur. J. Pharm. Med. Res"},{"key":"10.1016\/j.arr.2023.101960_bib313","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3389\/fphar.2015.00221","article-title":"\u03b2-Amyloid: The key peptide in the pathogenesis of Alzheimer\u2019s disease","volume":"6","author":"Sun","year":"2015","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.arr.2023.101960_bib314","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1002\/elps.200410203","article-title":"Precision improvement for the analysis of flavonoids in selected Thai plants by capillary zone electrophoresis","volume":"26","author":"Suntornsuk","year":"2005","journal-title":"Electrophoresis"},{"key":"10.1016\/j.arr.2023.101960_bib315","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/695936","article-title":"Moringa oleifera mitigates memory impairment and neurodegeneration in animal model of age-related dementia","volume":"2013","author":"Sutalangka","year":"2013","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.arr.2023.101960_bib316","doi-asserted-by":"crossref","first-page":"546","DOI":"10.3390\/ph15050546","article-title":"Virtual therapy with the NMDA antagonist memantine in hippocampal models of moderate to severe Alzheimer\u2019s disease, in silico trials","volume":"15","author":"Swietlik","year":"2022","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.arr.2023.101960_bib317","first-page":"224","article-title":"Antibacterial potentials of some herbal preparation available in India","volume":"4","author":"Tambekar","year":"2009","journal-title":"Res. J. Med. Med. Sci."},{"key":"10.1016\/j.arr.2023.101960_bib318","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.2174\/0929867322666150521091333","article-title":"Structure diversity, synthesis, and biological activity of cyathane diterpenoids in higher fungi","volume":"22","author":"Tang","year":"2015","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.arr.2023.101960_bib319","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1039\/C8FO02506A","article-title":"Evaluation of the anti-inflammatory properties of the active constituents in Ginkgo biloba for the treatment of pulmonary diseases","volume":"10","author":"Tao","year":"2019","journal-title":"Food Funct."},{"key":"10.1016\/j.arr.2023.101960_bib320","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1076\/1388-0209(200001)3811-BFT051","article-title":"Influence of Clitoriaternatea extracts on memory and central cholinergic activity in rats","volume":"38","author":"Taranalli","year":"2000","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.arr.2023.101960_bib321","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1021\/jf404463v","article-title":"Vitamin B12[c-lactone], a biologically inactive corrinoid compound, occurs in cultured and dried lion\u2019s mane mushroom (Hericium erinaceus) fruiting bodies","volume":"62","author":"Teng","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.arr.2023.101960_bib322","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1124\/jpet.102.041616","article-title":"The cholinergic hypothesis of age and Alzheimer\u2019s disease-related cognitive deficits: recent challenges and their implications for novel drug development","volume":"306","author":"Terry","year":"2003","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.arr.2023.101960_bib323","first-page":"1","article-title":"Ayurvedic medicinal importance of Shankhpushpi (Convolvulus pluricaulis): potential cognition boosting herb","volume":"10","author":"Thakur","year":"2021","journal-title":"Int. J. Pharm. Sci. Health Care"},{"key":"10.1016\/j.arr.2023.101960_bib324","first-page":"215","article-title":"Effect of Centella asiatica on mild cognitive impairment (MCI) and other common age-related clinical problems","volume":"3","author":"Tiwari","year":"2008","journal-title":"Dig. J. Nanomater. Biostructures."},{"key":"10.1016\/j.arr.2023.101960_bib325","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1097\/00001756-200006260-00035","article-title":"Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells","volume":"11","author":"Tohda","year":"2000","journal-title":"Neuroreport"},{"key":"10.1016\/j.arr.2023.101960_bib326","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12929-016-0266-z","article-title":"Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer\u2019s disease-related pathologies in APPswe\/PS1dE9 transgenic mice","volume":"23","author":"Tsai-Teng","year":"2016","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.arr.2023.101960_bib327","doi-asserted-by":"crossref","first-page":"598","DOI":"10.3390\/ijms19020598","article-title":"The cyanthin diterpenoid and sesterterpene constituents of Hericium erinaceus mycelium ameliorate Alzheimer\u2019s disease-related pathologies in APP\/PS1 transgenic mice","volume":"19","author":"Tzeng","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.arr.2023.101960_bib328","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jep.2009.09.056","article-title":"Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model","volume":"127","author":"Uabundit","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.arr.2023.101960_bib329","doi-asserted-by":"crossref","first-page":"20190102","DOI":"10.1515\/jcim-2019-0102","article-title":"In vivo neuroprotective, antinociceptive, anti-inflammatory potential in Swiss albino mice and in vitro antioxidant and clot lysis activities of fractionated Holigarna longifolia Roxb. bark extract","volume":"17","author":"Uddin","year":"2020","journal-title":"J. Complement. Integr. Med."},{"key":"10.1016\/j.arr.2023.101960_bib330","doi-asserted-by":"crossref","first-page":"5243","DOI":"10.3390\/molecules25225243","article-title":"Important flavonoids and their role as a therapeutic agent","volume":"25","author":"Ullah","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.arr.2023.101960_bib331","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.bbrc.2012.08.133","article-title":"Withaferin A inhibits JAK\/STAT3 signaling and induces apoptosis of human renal carcinoma Caki cells","volume":"427","author":"Um","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.arr.2023.101960_bib332","doi-asserted-by":"crossref","first-page":"44419","DOI":"10.1371\/journal.pone.0044419","article-title":"Differential activities of the two closely related withanolides, Withaferin A and Withanone: bioinformatics and experimental evidences","volume":"7","author":"Vaishnavi","year":"2012","journal-title":"PLOS One"},{"key":"10.1016\/j.arr.2023.101960_bib333","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/S0031-9422(00)82554-6","article-title":"2, 3-dihydrojaborosalactone A, a withanolide from Acnistus breviflorus","volume":"24","author":"Veleiro","year":"1985","journal-title":"Phytochem"},{"key":"10.1016\/j.arr.2023.101960_bib334","doi-asserted-by":"crossref","DOI":"10.1002\/syn.21952","article-title":"Curcuma treatment prevents cognitive deficit and alteration of neuronal morphology in the limbic system of aging rats","volume":"71","author":"Vidal","year":"2017","journal-title":"Synapse"},{"key":"10.1016\/j.arr.2023.101960_bib335","doi-asserted-by":"crossref","first-page":"5144","DOI":"10.1523\/JNEUROSCI.6437-11.2012","article-title":"Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment","volume":"32","author":"Wang","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.arr.2023.101960_bib336","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1021\/np5004388","article-title":"Erinacerins C\u2212L, isoindolin-1-ones with \u03b1-glucosidase inhibitory activity from cultures of the medicinal mushroom Hericium erinaceus","volume":"78","author":"Wang","year":"2015","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.arr.2023.101960_bib337","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.3233\/JAD-160763","article-title":"Role of Glutamate and NMDA receptors in Alzheimer\u2019s disease","volume":"57","author":"Wang","year":"2017","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"10.1016\/j.arr.2023.101960_bib338","doi-asserted-by":"crossref","first-page":"4175","DOI":"10.3390\/molecules27134175","article-title":"Role of natural compounds and target enzymes in the treatment of Alzheimer\u2019s disease","volume":"27","author":"Wang","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.arr.2023.101960_bib339","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/1472-6882-14-88","article-title":"Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer\u2019s disease drosophila models","volume":"14","author":"Wang","year":"2014","journal-title":"BMC Complement. Altern. Med."},{"key":"10.1016\/j.arr.2023.101960_bib340","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1590\/fst.02219","article-title":"In vitro anti-aging activities of Ginkgo biloba leaf extract and its chemical constituents","volume":"40","author":"Wang","year":"2020","journal-title":"Food Sci. Technol."},{"key":"10.1016\/j.arr.2023.101960_bib341","first-page":"187","article-title":"Structural features of a polysaccharide from Centella asiatica","volume":"15","author":"Wang","year":"2004","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.arr.2023.101960_bib342","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s11418-009-0360-6","article-title":"Antidepressant properties of bioactive fractions from the extract of Crocus sativus L. J","volume":"64","author":"Wang","year":"2010","journal-title":"Nat. Med"},{"key":"10.1016\/j.arr.2023.101960_bib343","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.3390\/nu6051861","article-title":"Vitamin B12-containing plant food sources for vegetarians","volume":"6","author":"Watanabe","year":"2014","journal-title":"Nutrients"},{"key":"10.1016\/j.arr.2023.101960_bib344","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jep.2007.11.038","article-title":"Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica","volume":"116","author":"Wattanathorn","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.arr.2023.101960_bib345","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.12688\/f1000research.14506.1","article-title":"Current understanding of Alzheimer\u2019s disease diagnosis and treatment","volume":"7","author":"Weller","year":"2018","journal-title":"F1000research"},{"key":"10.1016\/j.arr.2023.101960_bib346","doi-asserted-by":"crossref","first-page":"4862","DOI":"10.3390\/ijms23094862","article-title":"The role of the Microbiota-Gut-Brain Axis in the development of Alzheimer\u2019s disease","volume":"23","author":"Wiatrak","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.arr.2023.101960_bib347","series-title":"\u201cCentella asiatica (L.) Urb,\u201d in major herbs of Ayurveda","first-page":"102","author":"Williamson","year":"2002"},{"key":"10.1016\/j.arr.2023.101960_bib348","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3390\/antiox11020215","article-title":"Pharmacokinetics and pharmacodynamics of key components of a standardized Centella asiatica product in cognitively impaired older adults: a phase 1, double-blind, randomized clinical trial","volume":"11","author":"Wright","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.arr.2023.101960_bib349","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1021\/np500623s","article-title":"Erinaceolactones A to C, from the culture broth of Hericium erinaceus","volume":"78","author":"Wu","year":"2015","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.arr.2023.101960_bib350","doi-asserted-by":"crossref","first-page":"a006346","DOI":"10.1101\/cshperspect.a006346","article-title":"Inflammation in Alzheimer disease-A brief review of the basic science and clinical literature","volume":"2","author":"Wyss-Coray","year":"2012","journal-title":"Cold. Spring Harb. Perspect. Med."},{"key":"10.1016\/j.arr.2023.101960_bib351","first-page":"69","article-title":"Immunomodulatory effect of Ginkgo biloba exocarp polysaccharides on immunosuppressive mice induced by cyclophosphamide","volume":"22","author":"Xu","year":"2008","journal-title":"Chin. J. Pharmacol. Toxicol."},{"key":"10.1016\/j.arr.2023.101960_bib352","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13020-021-00514-2","article-title":"Comparison of the chemical constituents and anti-Alzheimer\u2019s disease effects of Uncaria rhynchophylla and Uncaria tomentosa","volume":"16","author":"Xu","year":"2021","journal-title":"Chin. Med."},{"key":"10.1016\/j.arr.2023.101960_bib353","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1016\/j.bmc.2008.10.091","article-title":"2, 3-Dihydrowithaferin A-3\u03b2-O-sulfate, a new potential prodrug of withaferin A from aeroponically grown Withania somnifera","volume":"17","author":"Xu","year":"2009","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.arr.2023.101960_bib354","doi-asserted-by":"crossref","first-page":"5892","DOI":"10.1074\/jbc.M404751200","article-title":"Curcumin inhibits formation of amyloid \u03b2 oligomers and fibrils, binds plaques, and reduces amyloid in vivo","volume":"280","author":"Yang","year":"2005","journal-title":"J. Biol. 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