{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T22:04:23Z","timestamp":1793484263195,"version":"4.5.0"},"reference-count":233,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100009377","name":"Education Department of Hunan Province","doi-asserted-by":"publisher","award":["CX20230802"],"award-info":[{"award-number":["CX20230802"]}],"id":[{"id":"10.13039\/100009377","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Hunan Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2023JJ60473"],"award-info":[{"award-number":["2023JJ60473"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002767","name":"China Hunan Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2023SK2048"],"award-info":[{"award-number":["2023SK2048"]}],"id":[{"id":"10.13039\/501100002767","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002767","name":"China Hunan Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2021CB1012"],"award-info":[{"award-number":["2021CB1012"]}],"id":[{"id":"10.13039\/501100002767","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014978","name":"Hunan University of Chinese Medicine","doi-asserted-by":"publisher","award":["202302"],"award-info":[{"award-number":["202302"]}],"id":[{"id":"10.13039\/501100014978","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ageing Research Reviews"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.arr.2025.102776","type":"journal-article","created":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T11:09:32Z","timestamp":1747480172000},"page":"102776","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Crosstalk between kidney and bones: New perspective for modulating osteoporosis"],"prefix":"10.1016","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7129-506X","authenticated-orcid":false,"given":"Yan","family":"Duan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-juan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-ting","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9866-6609","authenticated-orcid":false,"given":"Shun-xiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arr.2025.102776_bib1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/s41581-022-00665-x","article-title":"Regulation of FGF23 production and phosphate metabolism by bone-kidney interactions","volume":"19","author":"Agoro","year":"2023","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib2","first-page":"705","article-title":"Spatial transcriptomics of acute kidney injury","volume":"20","author":"Allison","year":"2024","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib3","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1002\/jbmr.3195","article-title":"Klotho lacks an FGF23-independent role in mineral homeostasis","volume":"32","author":"Andrukhova","year":"2017","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib4","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.mce.2016.07.035","article-title":"Fgf23 and parathyroid hormone signaling interact in kidney and bone","volume":"436","author":"Andrukhova","year":"2016","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.arr.2025.102776_bib5","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1002\/jbmr.5650110414","article-title":"The heritability of bone mineral density, ultrasound of the calcaneus and hip axis length: a study of postmenopausal twins","volume":"11","author":"Arden","year":"1996","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib6","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology. The gene ontology consortium","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat. Genet"},{"key":"10.1016\/j.arr.2025.102776_bib7","doi-asserted-by":"crossref","DOI":"10.3390\/toxins12120741","article-title":"Effects of fecal microbiota transplantation on composition in mice with CKD","volume":"12","author":"Barba","year":"2020","journal-title":"Toxins"},{"key":"10.1016\/j.arr.2025.102776_bib8","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.ccell.2016.10.009","article-title":"Extracellular vesicles in cancer: cell-to-cell mediators of metastasis","volume":"30","author":"Becker","year":"2016","journal-title":"Cancer Cell"},{"key":"10.1016\/j.arr.2025.102776_bib9","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.phrs.2015.04.016","article-title":"Nephrotoxicity of ibandronate and zoledronate in Wistar rats with normal renal function and after unilateral nephrectomy","volume":"99","author":"Bergner","year":"2015","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.arr.2025.102776_bib10","doi-asserted-by":"crossref","first-page":"b3692","DOI":"10.1136\/bmj.b3692","article-title":"Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials","volume":"339","author":"Bischoff-Ferrari","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.arr.2025.102776_bib11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S2213-8587(18)30347-4","article-title":"Vitamin D supplementation and musculoskeletal health","volume":"7","author":"Bischoff-Ferrari","year":"2019","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.arr.2025.102776_bib12","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1056\/NEJMcp1513724","article-title":"Clinical practice. Postmenopausal osteoporosis","volume":"374","author":"Black","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.arr.2025.102776_bib13","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1056\/NEJMoa030897","article-title":"Ten years' experience with alendronate for osteoporosis in postmenopausal women","volume":"350","author":"Bone","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.arr.2025.102776_bib14","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1038\/ki.2010.316","article-title":"The bone and mineral disorder of children undergoing chronic peritoneal dialysis","volume":"78","author":"Borzych","year":"2010","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib15","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1210\/er.2008-0004","article-title":"Vitamin D and human health: lessons from vitamin D receptor null mice","volume":"29","author":"Bouillon","year":"2008","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.arr.2025.102776_bib16","first-page":"227","article-title":"Osteoporosis, bone mineral density and CKD-MBD (II): therapeutic implications. Nefrologia","volume":"39","author":"Bover","year":"2019"},{"key":"10.1016\/j.arr.2025.102776_bib17","doi-asserted-by":"crossref","first-page":"544","DOI":"10.3803\/EnM.2021.301","article-title":"Long-term treatment of postmenopausal osteoporosis","volume":"36","author":"Brown","year":"2021","journal-title":"Endocrinol. Metab. (Seoul. )"},{"key":"10.1016\/j.arr.2025.102776_bib18","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1089\/ten.tea.2017.0069","article-title":"Renal regenerative potential of different extracellular vesicle populations derived from bone marrow mesenchymal stromal cells","volume":"23","author":"Bruno","year":"2017","journal-title":"Tissue Eng. Part A"},{"key":"10.1016\/j.arr.2025.102776_bib19","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1359\/jbmr.061113","article-title":"Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025","volume":"22","author":"Burge","year":"2007","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/jfb14080396","article-title":"Conditioned media from human pulp stem cell cultures improve bone regeneration in rat calvarial critical-size defects","volume":"14","author":"Buss","year":"2023","journal-title":"J. Funct. Biomater."},{"key":"10.1016\/j.arr.2025.102776_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4158\/GL-2020-0524SUPPL","article-title":"American association of clinical endocrinologists\/american college of endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis-2020 update","volume":"26","author":"Camacho","year":"2020","journal-title":"Endocr. Pr."},{"key":"10.1016\/j.arr.2025.102776_bib22","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/nrneph.2016.83","article-title":"Metabolism: Energy-efficient transport in the kidney","volume":"12","author":"Carney","year":"2016","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib23","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/nrendo.2014.51","article-title":"Geographic and ethnic disparities in osteoporotic fractures","volume":"10","author":"Cauley","year":"2014","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.arr.2025.102776_bib24","first-page":"28","article-title":"Bone morphogenetic protein-7: review of signalling and efficacy in fracture healing","volume":"4","author":"Cecchi","year":"2016","journal-title":"J. Orthop. Transl."},{"key":"10.1016\/j.arr.2025.102776_bib25","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nature25451","article-title":"\u03b1-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling","volume":"553","author":"Chen","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.arr.2025.102776_bib26","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1186\/s13018-023-04144-2","article-title":"Application of bone alkaline phosphatase and 25-oxhydryl-vitamin D in diagnosis and prediction of osteoporotic vertebral compression fractures","volume":"18","author":"Chen","year":"2023","journal-title":"J. Orthop. Surg. Res"},{"key":"10.1016\/j.arr.2025.102776_bib27","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1080\/03008207.2017.1290085","article-title":"Osteoblast-osteoclast interactions","volume":"59","author":"Chen","year":"2018","journal-title":"Connect. Tissue Res."},{"key":"10.1016\/j.arr.2025.102776_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2023.102158","article-title":"Spatial omics: an innovative frontier in aging research","volume":"93","author":"Chen","year":"2024","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.arr.2025.102776_bib29","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/jbmr.4187","article-title":"Opportunistic screening using low-dose CT and the prevalence of osteoporosis in china: a nationwide, multicenter study","volume":"36","author":"Cheng","year":"2021","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib30","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s00198-007-0490-1","article-title":"Salmon calcitonin: a review of current and future therapeutic indications","volume":"19","author":"Chesnut","year":"2008","journal-title":"Osteoporos. Int"},{"key":"10.1016\/j.arr.2025.102776_bib31","first-page":"267","article-title":"A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study","volume":"109","author":"Chesnut","year":"2000","journal-title":"PROOF Study Group. Am. J. Med."},{"key":"10.1016\/j.arr.2025.102776_bib32","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1359\/JBMR.040325","article-title":"Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis","volume":"19","author":"Chesnut","year":"2004","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib33","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1038\/s41551-019-0495-z","article-title":"On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology","volume":"4","author":"Chou","year":"2020","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.arr.2025.102776_bib34","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1681\/ASN.2010020134","article-title":"miR-192 mediates TGF-beta\/Smad3-driven renal fibrosis","volume":"21","author":"Chung","year":"2010","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2020.04.054","article-title":"SnapShot: extracellular vesicles","volume":"182","author":"Cocozza","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.arr.2025.102776_bib36","doi-asserted-by":"crossref","first-page":"4840","DOI":"10.1038\/s41467-020-18617-z","article-title":"Bone morphogenetic protein 7 promotes resistance to immunotherapy","volume":"11","author":"Cortez","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.arr.2025.102776_bib37","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1056\/NEJMoa1607948","article-title":"Romosozumab treatment in postmenopausal women with osteoporosis","volume":"375","author":"Cosman","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.arr.2025.102776_bib38","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00223-021-00924-2","article-title":"Role of the microbiome in regulating bone metabolism and susceptibility to osteoporosis","volume":"110","author":"Cronin","year":"2022","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.arr.2025.102776_bib39","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1056\/NEJMoa0809493","article-title":"Denosumab for prevention of fractures in postmenopausal women with osteoporosis","volume":"361","author":"Cummings","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.arr.2025.102776_bib40","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.physio.2022.11.001","article-title":"Physiotherapy post vertebral fragility fracture: a scoping review","volume":"119","author":"Cunningham","year":"2023","journal-title":"Physiotherapy"},{"key":"10.1016\/j.arr.2025.102776_bib41","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1007\/s00424-022-02714-7","article-title":"Fount, fate, features, and function of renal erythropoietin-producing cells","volume":"474","author":"Dahl","year":"2022","journal-title":"Pflug. Arch."},{"key":"10.1016\/j.arr.2025.102776_bib42","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.jpba.2010.06.017","article-title":"Erythropoietin (EPO) immunoaffinity columns--a powerful tool for purifying EPO and its recombinant analogues","volume":"53","author":"Dehnes","year":"2010","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.arr.2025.102776_bib43","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1002\/jbmr.1997","article-title":"SNP rs6265 regulates protein phosphorylation and osteoblast differentiation and influences BMD in humans","volume":"28","author":"Deng","year":"2013","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib44","first-page":"37","article-title":"Bone-organ axes: bidirectional crosstalk","volume":"11","author":"Deng","year":"2024","journal-title":"Mil. Med Res"},{"key":"10.1016\/j.arr.2025.102776_bib45","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1093\/eurjhf\/hfq106","article-title":"Relations of serum phosphorus levels to echocardiographic left ventricular mass and incidence of heart failure in the community","volume":"12","author":"Dhingra","year":"2010","journal-title":"Eur. J. Heart Fail"},{"key":"10.1016\/j.arr.2025.102776_bib46","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cytogfr.2012.01.004","article-title":"FGF23\/Klotho axis: phosphorus, mineral metabolism and beyond","volume":"23","author":"Donate-Correa","year":"2012","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.arr.2025.102776_bib47","article-title":"Kidney tonifying traditional Chinese medicine: potential implications for the prevention and treatment of osteoporosis","volume":"13","author":"Duan","year":"2022","journal-title":"Front Pharm."},{"key":"10.1016\/j.arr.2025.102776_bib48","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.1002\/jbmr.520","article-title":"Osteoblast extracellular Ca2+\u2009-sensing receptor regulates bone development, mineralization, and turnover","volume":"26","author":"Dvorak-Ewell","year":"2011","journal-title":"J. Bone Miner. Res."},{"issue":"5","key":"10.1016\/j.arr.2025.102776_bib49","article-title":"Calcium, vitamin D or recombinant parathyroid hormone for managing post-thyroidectomy hypoparathyroidism","author":"Edafe","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.arr.2025.102776_bib50","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27185862","article-title":"Tocotrienol as a Protecting Agent against Glucocorticoid-Induced Osteoporosis: A Mini Review of Potential Mechanisms","volume":"27","author":"Ekeuku","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.arr.2025.102776_bib51","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/and.12500","article-title":"Beneficial effects of aminoguanidine on radiotherapy-induced kidney and testis injury","volume":"48","author":"Ekici","year":"2016","journal-title":"Andrologia"},{"key":"10.1016\/j.arr.2025.102776_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.112341","article-title":"Quercetin ameliorates bone loss in OVX rats by modulating the intestinal flora-SCFAs-inflammatory signaling axis","volume":"136","author":"Feng","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.arr.2025.102776_bib53","doi-asserted-by":"crossref","DOI":"10.1080\/0886022X.2023.2264396","article-title":"Bone marrow-derived exosomes promote inflammation and osteoclast differentiation in high-turnover renal osteodystrophy","volume":"45","author":"Fu","year":"2023","journal-title":"Ren. Fail"},{"key":"10.1016\/j.arr.2025.102776_bib54","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s10157-016-1363-8","article-title":"Mineral metabolism and cardiovascular disease in CKD","volume":"21","author":"Fujii","year":"2017","journal-title":"Clin. Exp. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib55","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s11914-024-00860-8","article-title":"Regulation of FGF23 production in osteocytes","volume":"22","author":"Fukumoto","year":"2024","journal-title":"Curr. Osteoporos. Rep."},{"key":"10.1016\/j.arr.2025.102776_bib56","article-title":"Heart and kidney organoids maintain organ-specific function in a microfluidic system","volume":"23","author":"Gabbin","year":"2023","journal-title":"Mater. Today Biol."},{"key":"10.1016\/j.arr.2025.102776_bib57","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1053\/j.ajkd.2022.06.011","article-title":"Calciphylaxis and kidney disease: a review","volume":"81","author":"Gallo Marin","year":"2023","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.arr.2025.102776_bib58","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/jor.21219","article-title":"Low dose erythropoietin stimulates bone healing in mice","volume":"29","author":"Garcia","year":"2011","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.arr.2025.102776_bib59","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adh8335","article-title":"Deciphering maternal-fetal cross-talk in the human placenta during parturition using single-cell RNA sequencing","volume":"16","author":"Garcia-Flores","year":"2024","journal-title":"Sci. Transl. Med"},{"key":"10.1016\/j.arr.2025.102776_bib60","doi-asserted-by":"crossref","first-page":"3239","DOI":"10.1007\/s11999-009-0846-2","article-title":"The synergistic effect of autograft and BMP-7 in the treatment of atrophic nonunions","volume":"467","author":"Giannoudis","year":"2009","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.arr.2025.102776_bib61","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1053\/j.ajkd.2021.06.031","article-title":"Diagnosis and management of osteoporosis in advanced kidney disease: a review","volume":"79","author":"Ginsberg","year":"2022","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.arr.2025.102776_bib62","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.bone.2015.05.024","article-title":"Inflammatory signaling induced bone loss","volume":"80","author":"Goldring","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.arr.2025.102776_bib63","article-title":"Teriparatide-associated hypercalcemia concomitant with acute kidney injury: a case-report","volume":"16","author":"Goto","year":"2024","journal-title":"Cur\u0113us"},{"key":"10.1016\/j.arr.2025.102776_bib64","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1038\/aps.2015.30","article-title":"The efficacy and safety of weekly 35-mg risedronate dosing regimen for Chinese postmenopausal women with osteoporosis or osteopenia: 1-year data","volume":"36","author":"Gu","year":"2015","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.arr.2025.102776_bib65","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/s12276-022-00915-9","article-title":"Dynamic network biomarker identifies cdkn1a-mediated bone mineralization in the triggering phase of osteoporosis","volume":"55","author":"Guo","year":"2023","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.arr.2025.102776_bib66","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s10238-012-0220-7","article-title":"Effects of erythropoietin on osteoblast proliferation and function","volume":"14","author":"Guo","year":"2014","journal-title":"Clin. Exp. Med."},{"key":"10.1016\/j.arr.2025.102776_bib67","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/978-3-030-91979-5_2","article-title":"Quantitative ultrasound (QUS) in the management of osteoporosis and assessment of fracture risk: an update","volume":"1364","author":"Hans","year":"2022","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.arr.2025.102776_bib68","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/s41581-022-00655-z","article-title":"Molecular mechanisms of kidney crosstalk with distant organs","volume":"19","author":"Hasegawa","year":"2023","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib69","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/s41551-019-0498-9","article-title":"Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips","volume":"4","author":"Herland","year":"2020","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.arr.2025.102776_bib70","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/s11657-013-0136-1","article-title":"Osteoporosis in the European Union: medical management, epidemiology and economic burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA","volume":"8","author":"Hernlund","year":"2013","journal-title":"Arch. Osteoporos."},{"key":"10.1016\/j.arr.2025.102776_bib71","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.kint.2017.01.037","article-title":"Applications of the CRISPR-Cas9 system in kidney research","volume":"92","author":"Higashijima","year":"2017","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib72","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.bone.2011.08.004","article-title":"Erythropoietin stimulates bone formation, cell proliferation, and angiogenesis in a femoral segmental defect model in mice","volume":"49","author":"Holstein","year":"2011","journal-title":"Bone"},{"key":"10.1016\/j.arr.2025.102776_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2021.120819","article-title":"Bone targeting nanocarrier-assisted delivery of adenosine to combat osteoporotic bone loss","volume":"273","author":"Hoque","year":"2021","journal-title":"Biomaterials"},{"key":"10.1016\/j.arr.2025.102776_bib74","first-page":"303","article-title":"Pathophysiology of the chronic kidney disease-mineral bone disorder","volume":"24","author":"Hruska","year":"2015","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"10.1016\/j.arr.2025.102776_bib75","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.bone.2017.01.023","article-title":"The chronic kidney disease - Mineral bone disorder (CKD-MBD): advances in pathophysiology","volume":"100","author":"Hruska","year":"2017","journal-title":"Bone"},{"key":"10.1016\/j.arr.2025.102776_bib76","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232012223","article-title":"Mineral bone disorders in kidney disease patients: the ever-current topic","volume":"23","author":"Hu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.arr.2025.102776_bib77","first-page":"29","article-title":"Bone\/cartilage organoid on-chip: construction strategy and application","volume":"25","author":"Hu","year":"2023","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.arr.2025.102776_bib78","doi-asserted-by":"crossref","first-page":"4198","DOI":"10.1038\/s41467-018-06753-6","article-title":"Structural insights on TRPV5 gating by endogenous modulators","volume":"9","author":"Hughes","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.arr.2025.102776_bib79","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/s41576-022-00466-9","article-title":"Human organs-on-chips for disease modelling, drug development and personalized medicine","volume":"23","author":"Ingber","year":"2022","journal-title":"Nat. Rev. Genet"},{"key":"10.1016\/j.arr.2025.102776_bib80","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.bone.2015.07.015","article-title":"Altered material properties are responsible for bone fragility in rats with chronic kidney injury","volume":"81","author":"Iwasaki","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.arr.2025.102776_bib81","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1006\/excr.1996.3411","article-title":"BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye","volume":"230","author":"Jena","year":"1997","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.arr.2025.102776_bib82","first-page":"121","article-title":"Menatetrenone versus alfacalcidol in the treatment of Chinese postmenopausal women with osteoporosis: a multicenter, randomized, double-blinded, double-dummy, positive drug-controlled clinical trial","author":"Jiang","year":"2014","journal-title":"Clin. Inter. Aging 9"},{"key":"10.1016\/j.arr.2025.102776_bib83","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1038\/s41467-021-23642-7","article-title":"A functional motif of long noncoding RNA Nron against osteoporosis","volume":"12","author":"Jin","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.arr.2025.102776_bib84","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.mcna.2020.06.004","article-title":"Osteoporosis in older adults","volume":"104","author":"Johnston","year":"2020","journal-title":"Med. Clin. North Am."},{"key":"10.1016\/j.arr.2025.102776_bib85","article-title":"Potential of novel EPO derivatives in limb ischemia","volume":"2012","author":"Joshi","year":"2012","journal-title":"Cardiol. Res Pr."},{"key":"10.1016\/j.arr.2025.102776_bib86","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.semnephrol.2018.05.009","article-title":"Personalized management of bone and mineral disorders and precision medicine in end-stage kidney disease","volume":"38","author":"Jovanovich","year":"2018","journal-title":"Semin. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib87","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1053\/j.ajkd.2005.05.020","article-title":"Association of morbid obesity and weight change over time with cardiovascular survival in hemodialysis population","volume":"46","author":"Kalantar-Zadeh","year":"2005","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.arr.2025.102776_bib88","doi-asserted-by":"crossref","first-page":"D545","DOI":"10.1093\/nar\/gkaa970","article-title":"KEGG: integrating viruses and cellular organisms","volume":"49","author":"Kanehisa","year":"2021","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.arr.2025.102776_bib89","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1172\/JCI5705","article-title":"Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia","volume":"104","author":"Kawaguchi","year":"1999","journal-title":"J. Clin. Invest"},{"issue":"2011","key":"10.1016\/j.arr.2025.102776_bib90","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/kisup.2013.93","article-title":"Uremic osteoporosis","volume":"3","author":"Kazama","year":"2013","journal-title":"Kidney Int Suppl."},{"key":"10.1016\/j.arr.2025.102776_bib91","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.kint.2017.04.006","article-title":"Executive summary of the 2017 KDIGO chronic kidney disease-mineral and bone disorder (CKD-MBD) guideline update: what's changed and why it matters","volume":"92","author":"Ketteler","year":"2017","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib92","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a031211","article-title":"Regulation of bone metabolism by sex steroids","volume":"8","author":"Khosla","year":"2018","journal-title":"Cold Spring Harb. Perspect. Med"},{"key":"10.1016\/j.arr.2025.102776_bib93","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1007\/s00018-015-2092-y","article-title":"Molecular specification of germ layers in vertebrate embryos","volume":"73","author":"Kiecker","year":"2016","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.arr.2025.102776_bib94","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/s41586-020-3034-x","article-title":"Creation of bladder assembloids mimicking tissue regeneration and cancer","volume":"588","author":"Kim","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.arr.2025.102776_bib95","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1136\/gut.2006.092460","article-title":"Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats","volume":"56","author":"Kinoshita","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.arr.2025.102776_bib96","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.cmet.2015.11.003","article-title":"PTH\/PTHrP receptor mediates cachexia in models of kidney failure and cancer","volume":"23","author":"Kir","year":"2016","journal-title":"Cell Metab."},{"key":"10.1016\/j.arr.2025.102776_bib97","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/ki.2009.414","article-title":"Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients","volume":"77","author":"Komaba","year":"2010","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib98","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.kint.2017.02.014","article-title":"Klotho expression in osteocytes regulates bone metabolism and controls bone formation","volume":"92","author":"Komaba","year":"2017","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib99","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1002\/jcsm.12722","article-title":"Secondary hyperparathyroidism, weight loss, and longer term mortality in haemodialysis patients: results from the DOPPS","volume":"12","author":"Komaba","year":"2021","journal-title":"J. Cachex-.-. Sarcopenia Muscle"},{"key":"10.1016\/j.arr.2025.102776_bib100","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/jcsm.12421","article-title":"Kidney cachexia or protein-energy wasting in chronic kidney disease: facts and numbers","volume":"10","author":"Koppe","year":"2019","journal-title":"J. Cachex-.-. Sarcopenia Muscle"},{"key":"10.1016\/j.arr.2025.102776_bib101","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s00774-011-0288-2","article-title":"FGF and ERK signaling coordinately regulate mineralization-related genes and play essential roles in osteocyte differentiation","volume":"30","author":"Kyono","year":"2012","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.arr.2025.102776_bib102","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0196684","article-title":"The hypoxia inducible factor\/erythropoietin (EPO)\/EPO receptor pathway is disturbed in a rat model of chronic kidney disease related anemia","volume":"13","author":"Landau","year":"2018","journal-title":"PLoS ONE"},{"key":"10.1016\/j.arr.2025.102776_bib103","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.bbrc.2022.06.101","article-title":"Exogenous BMP7 administration attenuated vascular calcification and improved bone disorders in chronic uremic rats","volume":"621","author":"Lee","year":"2022","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.arr.2025.102776_bib104","first-page":"2064","article-title":"Study on the mechanism of miR-23b-3p regulating osteogenicdifferentiation of renal interstitial fibroblasts and participating in Randall'splague formation","volume":"58","author":"Lei","year":"2023","journal-title":"Acta Univ. Med. Anhui"},{"key":"10.1016\/j.arr.2025.102776_bib105","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/sj.ki.5002009","article-title":"Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease","volume":"71","author":"Levin","year":"2007","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib106","first-page":"321","article-title":"Guidelines for clinical application of bone turnover biomarkers. Chin. J","volume":"14","author":"Li","year":"2021","journal-title":"Osteoporos. Bone Min. Res"},{"key":"10.1016\/j.arr.2025.102776_bib107","doi-asserted-by":"crossref","DOI":"10.1080\/0886022X.2023.2210227","article-title":"Relationships between blood bone metabolic biomarkers and anemia in patients with chronic kidney disease","volume":"45","author":"Li","year":"2023","journal-title":"Ren. Fail"},{"key":"10.1016\/j.arr.2025.102776_bib108","doi-asserted-by":"crossref","first-page":"114","DOI":"10.3389\/fphys.2015.00114","article-title":"Role of bone morphogenetic protein-7 in renal fibrosis","volume":"6","author":"Li","year":"2015","journal-title":"Front Physiol."},{"key":"10.1016\/j.arr.2025.102776_bib109","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2023.101981","article-title":"Prevention and treatment of inflammatory arthritis with traditional Chinese medicine: underlying mechanisms based on cell and molecular targets","volume":"89","author":"Li","year":"2023","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.arr.2025.102776_bib110","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122544","article-title":"Exosomes based strategies for cardiovascular diseases: opportunities and challenges","volume":"308","author":"Li","year":"2024","journal-title":"Biomaterials"},{"key":"10.1016\/j.arr.2025.102776_bib111","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.cca.2018.05.057","article-title":"Effect of uremic toxin-indoxyl sulfate on the skeletal system","volume":"484","author":"Liu","year":"2018","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.arr.2025.102776_bib112","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/cbin.10166","article-title":"Overexpression of vasostatin-1 protects hypoxia\/reoxygenation injuries in cardiomyocytes-endothelial cells transwell co-culture system","volume":"38","author":"Liu","year":"2014","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.arr.2025.102776_bib113","article-title":"Downregulation of miR\u2011146a inhibits osteoporosis in the jaws of ovariectomized rats by regulating the Wnt\/\u03b2\u2011catenin signaling pathway","volume":"47","author":"Liu","year":"2021","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.arr.2025.102776_bib114","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/3686749","article-title":"The interplay between immune system and microbiota in osteoporosis","volume":"2020","author":"Locantore","year":"2020","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.arr.2025.102776_bib115","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/s41573-020-0079-3","article-title":"Organs-on-chips: into the next decade","volume":"20","author":"Low","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.arr.2025.102776_bib116","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/s41581-023-00776-z","article-title":"MSC therapy for diabetic kidney disease and nephrotic syndrome","volume":"19","author":"Lu","year":"2023","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib117","first-page":"1416","article-title":"Effects of paricalcitol on bone metabolism and TGF-B\/BMP-7\/Smadsignaling pathway in rats with renal osteodystrophy. Chin","volume":"40","author":"Lu","year":"2024","journal-title":"J. Immu"},{"key":"10.1016\/j.arr.2025.102776_bib118","doi-asserted-by":"crossref","DOI":"10.1016\/j.tiv.2022.105318","article-title":"A Promising transwell co-culture cell model for silicosis","volume":"81","author":"Lv","year":"2022","journal-title":"Toxicol. Vitr."},{"key":"10.1016\/j.arr.2025.102776_bib119","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1056\/NEJMoa074941","article-title":"Zoledronic acid and clinical fractures and mortality after hip fracture","volume":"357","author":"Lyles","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.arr.2025.102776_bib120","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1038\/s41581-022-00608-6","article-title":"MicroRNAs in kidney injury and disease","volume":"18","author":"Mahtal","year":"2022","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib121","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s13539-011-0019-5","article-title":"Wasting in chronic kidney disease","volume":"2","author":"Mak","year":"2011","journal-title":"J. Cachex-.-. Sarcopenia Muscle"},{"key":"10.1016\/j.arr.2025.102776_bib122","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.jcyt.2018.02.368","article-title":"Bone marrow-mesenchymal stromal cell infusion in patients with chronic kidney disease: a safety study with 18 months of follow-up","volume":"20","author":"Makhlough","year":"2018","journal-title":"Cytotherapy"},{"key":"10.1016\/j.arr.2025.102776_bib123","doi-asserted-by":"crossref","first-page":"3485","DOI":"10.1007\/s00198-016-3675-7","article-title":"Association of bone turnover markers with volumetric bone loss, periosteal apposition, and fracture risk in older men and women: the AGES-Reykjavik longitudinal study","volume":"27","author":"Marques","year":"2016","journal-title":"Osteoporos. Int"},{"key":"10.1016\/j.arr.2025.102776_bib124","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s11914-020-00583-6","article-title":"Transcriptomics: a solution for renal osteodystrophy","volume":"18","author":"Martin","year":"2020","journal-title":"Curr. Osteoporos. Rep."},{"key":"10.1016\/j.arr.2025.102776_bib125","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.kint.2021.05.027","article-title":"Running interference: lumasiran and other RNA interference therapeutics for kidney diseases","volume":"101","author":"Massy","year":"2022","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib126","first-page":"333","article-title":"Effect of risedronate on the risk of hip fracture in elderly women","volume":"344","author":"McClung","year":"2001","journal-title":"Hip Interv. Program Study Group. N. Engl. J. Med."},{"key":"10.1016\/j.arr.2025.102776_bib127","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.cell.2021.02.002","article-title":"Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption","volume":"184","author":"McDonald","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.arr.2025.102776_bib128","article-title":"Integration of spatial and single-cell transcriptomics localizes epithelial cell-immune cross-talk in kidney injury","volume":"6","author":"Melo Ferreira","year":"2021","journal-title":"JCI Insight"},{"key":"10.1016\/j.arr.2025.102776_bib129","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1359\/jbmr.2003.18.6.1139","article-title":"Adverse outcomes of osteoporotic fractures in the general population","volume":"18","author":"Melton","year":"2003","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib130","doi-asserted-by":"crossref","DOI":"10.1530\/EC-21-0596","article-title":"Vitamin D and musculoskeletal health: outstanding aspects to be considered in the light of current evidence","volume":"11","author":"Mendes","year":"2022","journal-title":"Endocr. Connect"},{"issue":"1","key":"10.1016\/j.arr.2025.102776_bib131","article-title":"Calcium and vitamin D for increasing bone mineral density in premenopausal women","author":"M\u00e9ndez-S\u00e1nchez","year":"2023","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.arr.2025.102776_bib132","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1096\/fj.06-6304fje","article-title":"The calcium sensing receptor is directly involved in both osteoclast differentiation and apoptosis","volume":"20","author":"Mentaverri","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.arr.2025.102776_bib133","doi-asserted-by":"crossref","first-page":"9197","DOI":"10.1073\/pnas.150246097","article-title":"In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism","volume":"97","author":"Meyer","year":"2000","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.arr.2025.102776_bib134","doi-asserted-by":"crossref","DOI":"10.1038\/boneres.2014.44","article-title":"Chronic kidney disease and the skeleton","volume":"2","author":"Miller","year":"2014","journal-title":"Bone Res."},{"key":"10.1016\/j.arr.2025.102776_bib135","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1053\/j.ajkd.2013.12.018","article-title":"Bone disease in CKD: a focus on osteoporosis diagnosis and management","volume":"64","author":"Miller","year":"2014","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.arr.2025.102776_bib136","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jsbmb.2016.04.001","article-title":"Genetic disorders of Vitamin D biosynthesis and degradation","volume":"165","author":"Miller","year":"2017","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.arr.2025.102776_bib137","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1002\/jbmr.2058","article-title":"Renal safety in patients treated with bisphosphonates for osteoporosis: a review","volume":"28","author":"Miller","year":"2013","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib138","doi-asserted-by":"crossref","DOI":"10.1111\/acel.12795","article-title":"Differential aging-related changes in neurophysiology and gene expression in IB4-positive and IB4-negative nociceptive neurons","volume":"17","author":"Mis","year":"2018","journal-title":"Aging Cell"},{"key":"10.1016\/j.arr.2025.102776_bib139","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s11914-017-0364-1","article-title":"Renal osteodystrophy or kidney-induced osteoporosis","volume":"15","author":"Moe","year":"2017","journal-title":"Curr. Osteoporos. Rep."},{"key":"10.1016\/j.arr.2025.102776_bib140","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1038\/sj.ki.5000414","article-title":"Definition, evaluation, and classification of renal osteodystrophy: a position statement from kidney disease: improving global outcomes (KDIGO)","volume":"69","author":"Moe","year":"2006","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib141","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/s41588-018-0302-x","article-title":"An atlas of genetic influences on osteoporosis in humans and mice","volume":"51","author":"Morris","year":"2019","journal-title":"Nat. Genet"},{"key":"10.1016\/j.arr.2025.102776_bib142","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/s13059-020-01997-2","article-title":"Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts","volume":"21","author":"Mullin","year":"2020","journal-title":"Genome Biol."},{"key":"10.1016\/j.arr.2025.102776_bib143","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1136\/bjsports-2017-098890","article-title":"Risk factors for patellofemoral pain: a systematic review and meta-analysis","volume":"53","author":"Neal","year":"2019","journal-title":"Br. J. Sports Med."},{"key":"10.1016\/j.arr.2025.102776_bib144","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1056\/NEJM200105103441904","article-title":"Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis","volume":"344","author":"Neer","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.arr.2025.102776_bib145","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.jacbts.2020.02.002","article-title":"Targeting vascular calcification in chronic kidney disease","volume":"5","author":"Nelson","year":"2020","journal-title":"JACC Basic Transl. Sci."},{"key":"10.1016\/j.arr.2025.102776_bib146","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1002\/jbmr.3125","article-title":"Identification of hip BMD loss and fracture risk markers through population-based serum proteomics","volume":"32","author":"Nielson","year":"2017","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib147","doi-asserted-by":"crossref","first-page":"F753","DOI":"10.1152\/ajprenal.00528.2017","article-title":"Klotho and activin A in kidney injury: plasma Klotho is maintained in unilateral obstruction despite no upregulation of Klotho biosynthesis in the contralateral kidney","volume":"314","author":"Nordholm","year":"2018","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.arr.2025.102776_bib148","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jnutbio.2017.08.007","article-title":"Circulating levels of miR-7, miR-152 and miR-192 respond to vitamin D supplementation in adults with prediabetes and correlate with improvements in glycemic control","volume":"49","author":"Nunez Lopez","year":"2017","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.arr.2025.102776_bib149","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.semnephrol.2019.02.009","article-title":"CKD hotspots: challenges and areas of opportunity","volume":"39","author":"Obrador","year":"2019","journal-title":"Semin. Nephrol."},{"issue":"10","key":"10.1016\/j.arr.2025.102776_bib150","article-title":"Regimens of vitamin D supplementation for women during pregnancy","author":"Palacios","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.arr.2025.102776_bib151","doi-asserted-by":"crossref","first-page":"7498","DOI":"10.1073\/pnas.131029498","article-title":"Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction","volume":"98","author":"Panda","year":"2001","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.arr.2025.102776_bib152","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1053\/j.ajkd.2020.12.024","article-title":"Osteoporosis and chronic kidney disease-mineral and bone disorder (CKD-MBD): back to basics","volume":"78","author":"Pazianas","year":"2021","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.arr.2025.102776_bib153","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41413-023-00244-1","article-title":"Comprehensive overview of microRNA function in rheumatoid arthritis","volume":"11","author":"Peng","year":"2023","journal-title":"Bone Res"},{"key":"10.1016\/j.arr.2025.102776_bib154","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1046\/j.1523-1755.2002.00658.x","article-title":"Mortality risk in hemodialysis patients and changes in nutritional indicators: DOPPS","volume":"62","author":"Pifer","year":"2002","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib155","doi-asserted-by":"crossref","first-page":"344","DOI":"10.2215\/CJN.05840513","article-title":"Disordered FGF23 and mineral metabolism in children with CKD","volume":"9","author":"Portale","year":"2014","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib156","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cca.2021.08.032","article-title":"Vitamin D deficiency in chronic kidney disease: myth or reality","volume":"523","author":"Priyadarshini","year":"2021","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.arr.2025.102776_bib157","doi-asserted-by":"crossref","first-page":"818","DOI":"10.7326\/M15-1361","article-title":"Treatment of low bone density or osteoporosis to prevent fractures in men and women: a clinical practice guideline update from the american college of physicians","volume":"166","author":"Qaseem","year":"2017","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.arr.2025.102776_bib158","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1002\/jbmr.2857","article-title":"Increased EPO levels are associated with bone loss in mice lacking PHD2 in EPO-producing cells","volume":"31","author":"Rauner","year":"2016","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib159","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/s41413-021-00157-x","article-title":"Epo\/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss","volume":"9","author":"Rauner","year":"2021","journal-title":"Bone Res."},{"key":"10.1016\/j.arr.2025.102776_bib160","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/S0140-6736(21)02646-5","article-title":"Drug therapy for osteoporosis in older adults","volume":"399","author":"Reid","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.arr.2025.102776_bib161","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1002\/jcb.23051","article-title":"Suppression of PTH by the vitamin D analog eldecalcitol is modulated by its high affinity for the serum vitamin D-binding protein and resistance to metabolism","volume":"112","author":"Ritter","year":"2011","journal-title":"J. Cell. Biochem"},{"key":"10.1016\/j.arr.2025.102776_bib162","doi-asserted-by":"crossref","DOI":"10.1111\/eci.13588","article-title":"Interplay between gut microbiota, bone health and vascular calcification in chronic kidney disease","volume":"51","author":"Rodrigues","year":"2021","journal-title":"Eur. J. Clin. Invest"},{"key":"10.1016\/j.arr.2025.102776_bib163","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1681\/ASN.2017050584","article-title":"Diagnostic accuracy of biomarkers and imaging for bone turnover in renal osteodystrophy","volume":"29","author":"Salam","year":"2018","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib164","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nrendo.2016.12","article-title":"BMP signalling in skeletal development, disease and repair","volume":"12","author":"Salazar","year":"2016","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.arr.2025.102776_bib165","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1080\/19490976.2016.1256525","article-title":"Nutrition and the gut microbiome in the elderly","volume":"8","author":"Salazar","year":"2017","journal-title":"Gut Microbes"},{"key":"10.1016\/j.arr.2025.102776_bib166","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1302\/2046-3758.74.BJR-2017-0302.R1","article-title":"The influence of age and osteoporosis on bone marrow stem cells from rats","volume":"7","author":"Sanghani-Kerai","year":"2018","journal-title":"Bone Res."},{"key":"10.1016\/j.arr.2025.102776_bib167","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1097\/TP.0000000000000903","article-title":"The kidney-vascular-bone axis in the chronic kidney disease-mineral bone disorder","volume":"100","author":"Seifert","year":"2016","journal-title":"Transplantation"},{"key":"10.1016\/j.arr.2025.102776_bib168","first-page":"405","article-title":"High proportion strontium-doped micro-arc oxidation coatings enhance early osseointegration of titanium in osteoporosis by anti-oxidative stress pathway","volume":"10","author":"Shen","year":"2022","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.arr.2025.102776_bib169","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/1240301","article-title":"CCR2 positive exosome released by mesenchymal stem cells suppresses macrophage functions and alleviates ischemia\/reperfusion-induced renal injury","volume":"2016","author":"Shen","year":"2016","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.arr.2025.102776_bib170","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1002\/sctm.20-0308","article-title":"Safety and efficacy of Wharton's jelly-derived mesenchymal stem cells with teriparatide for osteoporotic vertebral fractures: a phase I\/IIa study","volume":"10","author":"Shim","year":"2021","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.arr.2025.102776_bib171","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1359\/JBMR.0301264","article-title":"FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis","volume":"19","author":"Shimada","year":"2004","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.arr.2025.102776_bib172","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1096\/fj.07-098954","article-title":"Angiotensin II accelerates osteoporosis by activating osteoclasts","volume":"22","author":"Shimizu","year":"2008","journal-title":"FASEB J."},{"key":"10.1016\/j.arr.2025.102776_bib173","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0010853","article-title":"Erythropoietin couples hematopoiesis with bone formation","volume":"5","author":"Shiozawa","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.arr.2025.102776_bib174","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1007\/s00198-015-3093-2","article-title":"Projection of osteoporosis-related fractures and costs in China: 2010-2050","volume":"26","author":"Si","year":"2015","journal-title":"Osteoporos. Int"},{"key":"10.1016\/j.arr.2025.102776_bib175","doi-asserted-by":"crossref","first-page":"4710","DOI":"10.1172\/JCI64986","article-title":"Circulating \u03b1Klotho influences phosphate handling by controlling FGF23 production","volume":"122","author":"Smith","year":"2012","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.arr.2025.102776_bib176","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.mce.2011.05.018","article-title":"Vitamin D metabolism, cartilage and bone fracture repair","volume":"347","author":"St-Arnaud","year":"2011","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.arr.2025.102776_bib177","doi-asserted-by":"crossref","first-page":"R93","DOI":"10.1530\/EJE-15-0155","article-title":"Management of endocrine disease: diabetes and osteoporosis: cause for concern","volume":"173","author":"Starup-Linde","year":"2015","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.arr.2025.102776_bib178","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20071671","article-title":"The effect of conditioned media of stem cells derived from lipoma and adipose tissue on macrophages' response and wound healing in indirect co-culture system in vitro","volume":"20","author":"Stojanovi\u0107","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.arr.2025.102776_bib179","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/6782653","article-title":"Current progress on microrna-based gene delivery in the treatment of osteoporosis and osteoporotic fracture","volume":"2019","author":"Sun","year":"2019","journal-title":"Int. J. Endocrinol."},{"key":"10.1016\/j.arr.2025.102776_bib180","doi-asserted-by":"crossref","first-page":"11685","DOI":"10.1096\/fj.202000888R","article-title":"Erythropoietin signaling in osteoblasts is required for normal bone formation and for bone loss during erythropoietin-stimulated erythropoiesis","volume":"34","author":"Suresh","year":"2020","journal-title":"FASEB J."},{"key":"10.1016\/j.arr.2025.102776_bib181","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1159\/000488864","article-title":"Differential determinants of tubular phosphate reabsorption: insights on renal excretion of phosphates in kidney disease","volume":"47","author":"Tabibzadeh","year":"2018","journal-title":"Am. J. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib182","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.kint.2023.11.035","article-title":"Advancements in therapeutic development: kidney organoids and organs on a chip","volume":"105","author":"Tabibzadeh","year":"2024","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib183","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ijsu.2014.11.047","article-title":"Effect of Otostegia persica extraction on renal injury induced by hindlimb ischemia-reperfusion: a rat model","volume":"13","author":"Takhtfooladi","year":"2015","journal-title":"Int. J. Surg. (Lond., Engl. )"},{"key":"10.1016\/j.arr.2025.102776_bib184","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.7150\/ijms.44231","article-title":"Dexamethasone inhibits BMP7-induced osteogenic differentiation in rat dental follicle cells via the PI3K\/AKT\/GSK-3\u03b2\/\u03b2-catenin pathway","volume":"17","author":"Tang","year":"2020","journal-title":"Int. J. Med Sci."},{"key":"10.1016\/j.arr.2025.102776_bib185","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20102381","article-title":"Renal regenerative potential of extracellular vesicles derived from miRNA-engineered mesenchymal stromal cells","volume":"20","author":"Tapparo","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.arr.2025.102776_bib186","doi-asserted-by":"crossref","first-page":"4616","DOI":"10.1038\/s41598-019-40851-9","article-title":"In vitro metabolic activation of vitamin D3 by using a multi-compartment microfluidic liver-kidney organ on chip platform","volume":"9","author":"Theobald","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.arr.2025.102776_bib187","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.cell.2016.01.043","article-title":"Communication by extracellular vesicles: where we are and where we need to go","volume":"164","author":"Tkach","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.arr.2025.102776_bib188","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073554","article-title":"Bmp7 maintains undifferentiated kidney progenitor population and determines nephron numbers at birth","volume":"8","author":"Tomita","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.arr.2025.102776_bib189","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0170654","article-title":"Effects of the administration of 25(OH) vitamin D3 in an experimental model of chronic kidney disease in animals null for 1-alpha-hydroxylase","volume":"12","author":"Torremad\u00e9","year":"2017","journal-title":"PLoS ONE"},{"key":"10.1016\/j.arr.2025.102776_bib190","doi-asserted-by":"crossref","DOI":"10.3390\/cells10082140","article-title":"Erythropoietin (EPO) as a key regulator of erythropoiesis, bone remodeling and endothelial transdifferentiation of multipotent mesenchymal stem cells (MSCs): implications in regenerative medicine","volume":"10","author":"Tsiftsoglou","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.arr.2025.102776_bib191","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.immuni.2018.10.013","article-title":"The microbial metabolite butyrate stimulates bone formation via T regulatory cell-mediated regulation of WNT10B expression","volume":"49","author":"Tyagi","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.arr.2025.102776_bib192","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/nature05315","article-title":"Klotho converts canonical FGF receptor into a specific receptor for FGF23","volume":"444","author":"Urakawa","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.arr.2025.102776_bib193","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00198-010-1501-1","article-title":"Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards","volume":"22","author":"Vasikaran","year":"2011","journal-title":"Osteoporos. Int"},{"key":"10.1016\/j.arr.2025.102776_bib194","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.1001\/jama.295.23.joc60074","article-title":"Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP study of tamoxifen and raloxifene (STAR) P-2 trial","volume":"295","author":"Vogel","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.arr.2025.102776_bib195","doi-asserted-by":"crossref","first-page":"4597","DOI":"10.1016\/j.cell.2021.08.005","article-title":"Organs-on-a-chip models for biological research","volume":"184","author":"Vunjak-Novakovic","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.arr.2025.102776_bib196","doi-asserted-by":"crossref","first-page":"511","DOI":"10.3389\/fimmu.2014.00511","article-title":"Biology of the RANKL-RANK-OPG system in immunity, bone, and beyond","volume":"5","author":"Walsh","year":"2014","journal-title":"Front Immunol."},{"key":"10.1016\/j.arr.2025.102776_bib197","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/ndt\/gfs411","article-title":"Fibroblast growth factor 23 and soluble klotho in children with chronic kidney disease","volume":"28","author":"Wan","year":"2013","journal-title":"Nephrol. Dial. Transpl."},{"key":"10.1016\/j.arr.2025.102776_bib198","article-title":"Estimating the global prevalence of secondary hyperparathyroidism in patients with chronic kidney disease","volume":"15","author":"Wang","year":"2024","journal-title":"Front Endocrinol."},{"key":"10.1016\/j.arr.2025.102776_bib199","first-page":"487","article-title":"Effects of adeno-associated virus-mediated klotho gene delivery on theexpression of runx2 and MMP-13 gene in the bone of the ovariectomy rats. Basic","volume":"32","author":"Wang","year":"2012","journal-title":"Clin. Med."},{"key":"10.1016\/j.arr.2025.102776_bib200","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.jinf.2023.09.004","article-title":"Single-cell RNA-sequencing reveals heterogeneity and intercellular crosstalk in human tuberculosis lung","volume":"87","author":"Wang","year":"2023","journal-title":"J. Infect."},{"key":"10.1016\/j.arr.2025.102776_bib201","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.molcel.2015.05.005","article-title":"Advances and applications of single-cell sequencing technologies","volume":"58","author":"Wang","year":"2015","journal-title":"Mol. Cell"},{"key":"10.1016\/j.arr.2025.102776_bib202","first-page":"142","article-title":"Efficacy and safety of Jintiange capsule in the treatment of primaryosteoporosis: a randomized,double-blind,double-dummy,positive-controlled, multicenter clinical trial. Chin. J","volume":"15","author":"Wang","year":"2022","journal-title":"Osteoporos. Bone Min. Res."},{"key":"10.1016\/j.arr.2025.102776_bib203","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1038\/mt.2016.90","article-title":"Mesenchymal stem cells deliver exogenous MicroRNA-let7c via exosomes to attenuate renal fibrosis","volume":"24","author":"Wang","year":"2016","journal-title":"Mol. Ther."},{"key":"10.1016\/j.arr.2025.102776_bib204","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.21106","article-title":"Prevalence of osteoporosis and fracture in China: the China osteoporosis prevalence study","volume":"4","author":"Wang","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.arr.2025.102776_bib205","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2024.102408","article-title":"Osteoporosis and Alzheimer\u00b4s disease (or Alzheimer\u00b4s disease and Osteoporosis)","volume":"99","author":"Wanionok","year":"2024","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.arr.2025.102776_bib206","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1515\/cclm-2017-0483","article-title":"Circulating miR-21, miR-210 and miR-146a as potential biomarkers to differentiate acute tubular necrosis from hepatorenal syndrome in patients with liver cirrhosis: a pilot study","volume":"56","author":"Watany","year":"2018","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.arr.2025.102776_bib207","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.eprac.2021.02.001","article-title":"American association of clinical endocrinologists\/american college of endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis-2020 update","volume":"27","author":"Watts","year":"2021","journal-title":"Endocr. Pr."},{"key":"10.1016\/j.arr.2025.102776_bib208","doi-asserted-by":"crossref","first-page":"263","DOI":"10.2147\/IJNRD.S191156","article-title":"Chronic kidney disease-mineral and bone disorder (CKD-MBD): current perspectives","volume":"12","author":"Waziri","year":"2019","journal-title":"Int J. Nephrol. Renov. Dis."},{"key":"10.1016\/j.arr.2025.102776_bib209","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1016\/j.kint.2017.02.026","article-title":"Osteocyte dysfunction and renal osteodystrophy: not just calcium and phosphorus anymore","volume":"91","author":"Wesseling-Perry","year":"2017","journal-title":"Kidney Int"},{"key":"10.1016\/j.arr.2025.102776_bib210","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1681\/ASN.2019070677","article-title":"Mechanisms of metabolic acidosis-induced kidney injury in chronic kidney disease","volume":"31","author":"Wesson","year":"2020","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib211","doi-asserted-by":"crossref","DOI":"10.1111\/acel.12794","article-title":"MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment","volume":"17","author":"Xu","year":"2018","journal-title":"Aging Cell"},{"key":"10.1016\/j.arr.2025.102776_bib212","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/s41392-023-01467-8","article-title":"Targeting strategies for bone diseases: signaling pathways and clinical studies","volume":"8","author":"Xu","year":"2023","journal-title":"Signal Transduct. Target Ther."},{"key":"10.1016\/j.arr.2025.102776_bib213","first-page":"1574","article-title":"Exploration on the scientific connotation of 'kidney governing bonesfrom the perspective of the kidney regulating the material basis of bone. Chin. J. Tradit","volume":"37","author":"Xue","year":"2022","journal-title":"Chin. Med. Pharm."},{"key":"10.1016\/j.arr.2025.102776_bib214","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1158\/0008-5472.CAN-19-2348","article-title":"Therapy-induced senescence drives bone loss","volume":"80","author":"Yao","year":"2020","journal-title":"Cancer Res."},{"key":"10.1016\/j.arr.2025.102776_bib215","doi-asserted-by":"crossref","first-page":"3559","DOI":"10.1007\/s11255-024-04146-x","article-title":"Renal anemia: from relative insufficiency of EPO to imbalance of erythropoiesis and eryptosis","volume":"56","author":"Yuan","year":"2024","journal-title":"Int. Urol. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib216","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1038\/s41467-022-28096-z","article-title":"A Klotho-derived peptide protects against kidney fibrosis by targeting TGF-\u03b2 signaling","volume":"13","author":"Yuan","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.arr.2025.102776_bib217","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24065325","article-title":"Mouse MOdels of Mineral Bone Disorders Associated with Chronic Kidney Disease","volume":"24","author":"Zaloszyc","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.arr.2025.102776_bib218","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/s00467-008-0818-x","article-title":"Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease","volume":"23","author":"Zeisberg","year":"2008","journal-title":"Pediatr. Nephrol."},{"key":"10.1016\/j.arr.2025.102776_bib219","first-page":"1093","article-title":"Experimental specifications for biochemical indicators of bone metabolism in 2024","volume":"30","author":"Zhang","year":"2024","journal-title":"Chin. J. Osteoporos."},{"key":"10.1016\/j.arr.2025.102776_bib220","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.2147\/DDDT.S139804","article-title":"Total flavonoids from Rhizoma Drynariae (Gusuibu) for treating osteoporotic fractures: implication in clinical practice","volume":"11","author":"Zhang","year":"2017","journal-title":"Drug Des. Dev. Ther."},{"key":"10.1016\/j.arr.2025.102776_bib221","first-page":"469","article-title":"Expert consensus on clinical application of biochemical indicators of bonemetabolism (2023)","volume":"29","author":"Zhang","year":"2023","journal-title":"Chin. J. Osteoporos."},{"key":"10.1016\/j.arr.2025.102776_bib222","article-title":"The saturation effect of obesity on bone mineral density for older people: the NHANES 2017-2020","volume":"13","author":"Zhang","year":"2022","journal-title":"Front Endocrinol."},{"key":"10.1016\/j.arr.2025.102776_bib223","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2024.102196","article-title":"Targeting the gut microbiota-related metabolites for osteoporosis: the inextricable connection of gut-bone axis","volume":"94","author":"Zhang","year":"2024","journal-title":"Ageing Res. Rev."},{"issue":"4","key":"10.1016\/j.arr.2025.102776_bib224","first-page":"289","article-title":"Interpretation of key points in the diagnosis and treatment guidelines for primary osteoporosis","volume":"30","author":"Zhang","year":"2024","journal-title":"J. Criti. Care Internal Med."},{"key":"10.1016\/j.arr.2025.102776_bib225","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1210\/endrev\/bnad025","article-title":"Crosstalk between the neuroendocrine system and bone homeostasis","volume":"45","author":"Zhao","year":"2024","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.arr.2025.102776_bib226","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116543","article-title":"Icariin, the main prenylflavonoid of Epimedii Folium, ameliorated chronic kidney disease by modulating energy metabolism via AMPK activation","volume":"312","author":"Zhao","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.arr.2025.102776_bib227","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1039\/D1FO03494D","article-title":"Total flavonoids in Epimedium koreanum Nakai alleviated chronic renal failure via promoting AMPK activation","volume":"13","author":"Zhao","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.arr.2025.102776_bib228","doi-asserted-by":"crossref","DOI":"10.1172\/JCI164610","article-title":"Kidney glycolysis serves as a mammalian phosphate sensor that maintains phosphate homeostasis","volume":"133","author":"Zhou","year":"2023","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.arr.2025.102776_bib229","first-page":"2902","article-title":"Clinical study on epimedium total flavonoids capsules combined with alendronate sodium in treatment of primary osteoporosis(kidney-yang deficiency syndrome)","volume":"39","author":"Zhou","year":"2024","journal-title":"Drugs Clin."},{"key":"10.1016\/j.arr.2025.102776_bib230","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/s41413-021-00143-3","article-title":"Twelve years of GWAS discoveries for osteoporosis and related traits: advances, challenges and applications","volume":"9","author":"Zhu","year":"2021","journal-title":"Bone Res"},{"key":"10.1016\/j.arr.2025.102776_bib231","doi-asserted-by":"crossref","first-page":"7831","DOI":"10.1007\/s00018-021-03972-x","article-title":"\u03b1-Klotho released from HK-2 cells inhibits osteogenic differentiation of renal interstitial fibroblasts by inactivating the Wnt-\u03b2-catenin pathway","volume":"78","author":"Zhu","year":"2021","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.arr.2025.102776_bib232","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1142\/S0192415X21500877","article-title":"Network pharmacology analysis to explore the pharmacological mechanism of effective chinese medicines in treating metastatic colorectal cancer using meta-analysis approach","volume":"49","author":"Zhu","year":"2021","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.arr.2025.102776_bib233","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s00018-024-05408-8","article-title":"miR-148b-5p regulates hypercalciuria and calcium-containing nephrolithiasis","volume":"81","author":"Zhu","year":"2024","journal-title":"Cell. Mol. Life Sci."}],"container-title":["Ageing Research Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568163725001229?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568163725001229?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T21:55:10Z","timestamp":1762552510000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568163725001229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":233,"alternative-id":["S1568163725001229"],"URL":"https:\/\/doi.org\/10.1016\/j.arr.2025.102776","relation":{},"ISSN":["1568-1637"],"issn-type":[{"value":"1568-1637","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Crosstalk between kidney and bones: New perspective for modulating osteoporosis","name":"articletitle","label":"Article Title"},{"value":"Ageing Research Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arr.2025.102776","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102776"}}