{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T17:57:33Z","timestamp":1781287053484,"version":"3.54.1"},"reference-count":12,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013733","name":"Ipsen Biopharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013733","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014382","name":"Ipsen Pharma SAS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014382","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["archives-rrct.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Rehabilitation Research and Clinical Translation"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.arrct.2026.100611","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:36:07Z","timestamp":1773362167000},"page":"100611","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quality of Life Assessment Using the Leg Activity Measure in Ambulatory Individuals With Leg Spasticity: Findings From a Longitudinal, Observational Study Evaluating the Effectiveness of AbobotulinumtoxinA in Routine Practice"],"prefix":"10.1016","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5541-7063","authenticated-orcid":false,"given":"Stephen","family":"Ashford","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Esquenazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard D.","family":"Zorowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Beneteau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Maisonobe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Hannes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Jacinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arrct.2026.100611_bib0001","first-page":"111","article-title":"Epidemiological, humanistic, and economic burden of illness of lower limb spasticity in adults: a systematic review","volume":"10","author":"Martin","year":"2014","journal-title":"Neuropsychiatr Dis Treat"},{"key":"10.1016\/j.arrct.2026.100611_bib0002","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1161\/hs0202.102375","article-title":"Higher incidence of falls in long-term stroke survivors than in population controls: depressive symptoms predict falls after stroke","volume":"33","author":"J\u00f8rgensen","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.arrct.2026.100611_bib0003","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.apmr.2024.10.017","article-title":"Longitudinal goal attainment with repeat injections of abobotulinumtoxinA in adults with lower limb spasticity: results from a prospective observational study","volume":"106","author":"Esquenazi","year":"2025","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.arrct.2026.100611_bib0004","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1080\/09638288.2019.1697765","article-title":"The Leg Activity measure, a new measure of passive and active function and impact on quality of life; informing goal setting and outcome evaluation in leg spasticity","volume":"43","author":"Ashford","year":"2021","journal-title":"Disabil Rehabil"},{"key":"10.1016\/j.arrct.2026.100611_bib0005","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1080\/09638288.2019.1643933","article-title":"Psychometric evaluation of the leg activity measure (LegA) for outcome measurement in people with brain injury and spasticity","volume":"43","author":"Ashford","year":"2021","journal-title":"Disabil Rehabil"},{"key":"10.1016\/j.arrct.2026.100611_bib0006","doi-asserted-by":"crossref","first-page":"jrm4257","DOI":"10.2340\/jrm.v55.4257","article-title":"Clinical presentation of patients with lower limb spasticity undergoing routine treatment with botulinum toxin: baseline findings from an international observational study","volume":"55","author":"Esquenazi","year":"2023","journal-title":"J Rehabil Med"},{"key":"10.1016\/j.arrct.2026.100611_bib0007","doi-asserted-by":"crossref","DOI":"10.2340\/jrm.v57.42605","article-title":"Muscle selection and dosing in patients undergoing treatment with abobotulinumtoxinA for lower limb spasticity in real-world practice","volume":"57","author":"Zorowitz","year":"2025","journal-title":"J Rehabil Med"},{"key":"10.1016\/j.arrct.2026.100611_bib0008","doi-asserted-by":"crossref","first-page":"292","DOI":"10.3390\/toxins12050292","article-title":"Health-related quality of life outcomes from botulinum toxin treatment in spasticity","volume":"12","author":"Roncoroni","year":"2020","journal-title":"Toxins (Basel)"},{"key":"10.1016\/j.arrct.2026.100611_bib0009","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s12955-020-01304-4","article-title":"Quality of life in subjects with upper- and lower-limb spasticity treated with incobotulinumtoxinA","volume":"18","author":"Fheodoroff","year":"2020","journal-title":"Health Qual Life Outcomes"},{"key":"10.1016\/j.arrct.2026.100611_bib0010","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.apmr.2003.08.081","article-title":"The effect of combined use of botulinum toxin type A and functional electric stimulation in the treatment of spastic drop foot after stroke: a preliminary investigation","volume":"85","author":"Johnson","year":"2004","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.arrct.2026.100611_bib0011","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1212\/WNL.0000000000004687","article-title":"Efficacy and safety of abobotulinumtoxinA in spastic lower limb: Randomized trial and extension","volume":"89","author":"Gracies","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.arrct.2026.100611_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinepi.2024.111487","article-title":"Systematic review reveals that EQ-5D minimally important differences vary with treatment type and may decrease with increasing baseline score","volume":"174","author":"Cheng","year":"2024","journal-title":"J Clin Epidemiol"}],"container-title":["Archives of Rehabilitation Research and Clinical Translation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590109526000285?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590109526000285?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T17:16:02Z","timestamp":1781284562000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590109526000285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S2590109526000285"],"URL":"https:\/\/doi.org\/10.1016\/j.arrct.2026.100611","relation":{},"ISSN":["2590-1095"],"issn-type":[{"value":"2590-1095","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quality of Life Assessment Using the Leg Activity Measure in Ambulatory Individuals With Leg Spasticity: Findings From a Longitudinal, Observational Study Evaluating the Effectiveness of AbobotulinumtoxinA in Routine Practice","name":"articletitle","label":"Article Title"},{"value":"Archives of Rehabilitation Research and Clinical Translation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arrct.2026.100611","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of American Congress of Rehabilitation Medicine.","name":"copyright","label":"Copyright"}],"article-number":"100611"}}