{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:24:28Z","timestamp":1785198268515,"version":"3.55.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T00:00:00Z","timestamp":1646870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["arthroplastytoday.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroplasty Today"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.artd.2022.03.007","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T13:25:34Z","timestamp":1651065934000},"page":"125-131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["A Novel Mobile App-Based Neuromuscular Electrical Stimulation Therapy for Improvement of Knee Pain, Stiffness, and Function in Knee Osteoarthritis: A Randomized Trial"],"prefix":"10.1016","volume":"15","author":[{"given":"Oliver C.","family":"Sax","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin G.","family":"Gesheff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwin","family":"Mahajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirav","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taj-Jamal","family":"Andrews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alie","family":"Jreisat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilawar","family":"Ajani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diedre","family":"McMullen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Mbogua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dena","family":"Petersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5282-4026","authenticated-orcid":false,"given":"Vinod","family":"Dasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nebojsa","family":"Skrepnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5651-2625","authenticated-orcid":false,"given":"Ronald E.","family":"Delanois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.artd.2022.03.007_bib1","series-title":"Arthritis by the numbers\/book of trusted facts & figures","year":"2018"},{"key":"10.1016\/j.artd.2022.03.007_bib2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.15585\/mmwr.mm6609e1","article-title":"Vital signs: prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation \u2014 United States, 2013\u20132015","volume":"66","author":"Barbour","year":"2017","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.artd.2022.03.007_bib3","first-page":"205","article-title":"Knee osteoarthritis prevalence, risk factors, pathogenesis and features: Part I","volume":"2","author":"Heidari","year":"2011","journal-title":"Caspian J Intern Med"},{"key":"10.1016\/j.artd.2022.03.007_bib4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.cger.2010.03.001","article-title":"Epidemiology of osteoarthritis","volume":"26","author":"Zhang","year":"2010","journal-title":"Clin Geriatr Med"},{"key":"10.1016\/j.artd.2022.03.007_bib5","first-page":"571","article-title":"Treatment of osteoarthritis of the knee: evidence-based guideline, 2nd edition","volume":"21","author":"Jevsevar","year":"2013","journal-title":"J\u00a0Am Acad Orthop Surg"},{"key":"10.1016\/j.artd.2022.03.007_bib6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.7812\/TPP\/16-183","article-title":"Knee osteoarthritis: a primer","volume":"21","author":"Lespasio","year":"2017","journal-title":"Perm J"},{"key":"10.1016\/j.artd.2022.03.007_bib7","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1177\/1941738112445726","article-title":"Muscle impairments in patients with knee osteoarthritis","volume":"4","author":"Alnahdi","year":"2012","journal-title":"Sports Health"},{"key":"10.1016\/j.artd.2022.03.007_bib8","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0736-0266(03)00154-2","article-title":"Quadriceps femoris muscle weakness and activation failure in patients with symptomatic knee osteoarthritis","volume":"22","author":"Lewek","year":"2004","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.artd.2022.03.007_bib9","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1249\/MSS.0b013e31815ef285","article-title":"Mechanisms underlying quadriceps weakness in knee osteoarthritis","volume":"40","author":"Petterson","year":"2008","journal-title":"Med Sci Sports Exerc"},{"key":"10.1016\/j.artd.2022.03.007_bib10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.7326\/0003-4819-127-2-199707150-00001","article-title":"Quadriceps weakness and osteoarthritis of the knee","volume":"127","author":"Slemenda","year":"1997","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.artd.2022.03.007_bib11","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1589\/jpts.26.817","article-title":"Comparative study of hamstring and quadriceps strengthening treatments in the management of knee osteoarthritis","volume":"26","author":"Al-Johani","year":"2014","journal-title":"J\u00a0Phys Ther Sci"},{"key":"10.1016\/j.artd.2022.03.007_bib12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/1471-2474-11-119","article-title":"Effects of preoperative neuromuscular electrical stimulation on quadriceps strength and functional recovery in total knee arthroplasty. A pilot study","volume":"11","author":"Walls","year":"2010","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.artd.2022.03.007_bib13","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF01565458","article-title":"Electrical stimulation of vastus medialis and stretching of lateral thigh muscles in patients with Patello-femoral symptoms","volume":"1","author":"Werner","year":"1993","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.artd.2022.03.007_bib14","doi-asserted-by":"crossref","first-page":"320","DOI":"10.2165\/00007256-199213050-00003","article-title":"Neuromuscular electrical stimulation: an overview and its application in the treatment of sports injuries","volume":"13","author":"Lake","year":"1992","journal-title":"Sports Med"},{"issue":"6","key":"10.1016\/j.artd.2022.03.007_bib15","first-page":"909","article-title":"Neuromuscular Electrical Stimulation after total joint arthroplasty: a critical review of recent controlled studies","volume":"49","author":"Kittelson","year":"2013","journal-title":"Eur J Phys Rehabil Med"},{"key":"10.1016\/j.artd.2022.03.007_bib16","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00167-017-4669-5","article-title":"Neuromuscular electrical stimulation is effective in strengthening the quadriceps muscle after anterior cruciate ligament surgery","volume":"26","author":"Hauger","year":"2018","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"issue":"Suppl 7","key":"10.1016\/j.artd.2022.03.007_bib17","doi-asserted-by":"crossref","first-page":"S254","DOI":"10.21037\/atm.2019.09.150","article-title":"Use of home neuromuscular electrical stimulation in the first 6 weeks improves function and reduces pain after primary total knee arthroplasty: a matched comparison","volume":"7","author":"Delanois","year":"2019","journal-title":"Ann Transl Med"},{"key":"10.1016\/j.artd.2022.03.007_bib18","first-page":"221","article-title":"Use of an app-controlled neuromuscular electrical stimulation system for improved self-management of knee conditions and reduced costs","volume":"31","author":"Chughtai","year":"2017","journal-title":"Surg Technol Int"},{"key":"10.1016\/j.artd.2022.03.007_bib19","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.joca.2014.11.014","article-title":"Electrical stimulation for pain relief in knee osteoarthritis: systematic review and network meta-analysis","volume":"23","author":"Zeng","year":"2015","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.artd.2022.03.007_bib21","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/ard.16.4.494","article-title":"Radiological assessment of osteo-arthrosis","volume":"16","author":"Kellgren","year":"1957","journal-title":"Ann Rheum Dis"},{"issue":"12","key":"10.1016\/j.artd.2022.03.007_bib22","first-page":"1833","article-title":"Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee","volume":"15","author":"Bellamy","year":"1988","journal-title":"J\u00a0Rheumatol"},{"issue":"6","key":"10.1016\/j.artd.2022.03.007_bib23","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1007\/s11999-016-4719-1","article-title":"Validation of the KOOS, JR: a short-form knee arthroplasty outcomes survey","volume":"474","author":"Lyman","year":"2016","journal-title":"Clin Orthop Relat Res"},{"issue":"9","key":"10.1016\/j.artd.2022.03.007_bib24","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1002\/acr.22823","article-title":"Sensitivity to change of patient-preference measures for pain in patients with knee osteoarthritis: data from two trials","volume":"68","author":"Parkes","year":"2016","journal-title":"Arthritis Care Res"},{"key":"10.1016\/j.artd.2022.03.007_bib25","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1590\/S1516-31802013000100017","article-title":"Is neuromuscular electrical stimulation effective for improving pain, function and activities of daily living of knee osteoarthritis patients? A randomized clinical trial","volume":"131","author":"Imoto","year":"2013","journal-title":"Sao Paulo Med J"},{"key":"10.1016\/j.artd.2022.03.007_bib26","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/1471-2474-13-118","article-title":"Effects of home-based resistance training and neuromuscular electrical stimulation in knee osteoarthritis: a randomized controlled trial","volume":"13","author":"Bruce-Brand","year":"2012","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.artd.2022.03.007_bib27","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.2147\/CIA.S64104","article-title":"The effects of exercise and neuromuscular electrical stimulation in subjects with knee osteoarthritis: a 3-month follow-up study","volume":"9","author":"Laufer","year":"2014","journal-title":"Clin Interv Aging"},{"issue":"1","key":"10.1016\/j.artd.2022.03.007_bib28","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1186\/s13075-019-1951-6","article-title":"Meta-analysis of pain and function placebo responses in pharmacological osteoarthritis trials","volume":"21","author":"Huang","year":"2019","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.artd.2022.03.007_bib29","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.joca.2013.04.018","article-title":"Mechanisms of the placebo response in pain in osteoarthritis","volume":"21","author":"Abhishek","year":"2013","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.artd.2022.03.007_bib30","first-page":"1648","article-title":"Outcome variables for osteoarthritis clinical trials: the OMERACT-OARSI set of responder criteria","volume":"30","author":"Pham","year":"2003","journal-title":"J\u00a0Rheumatol"}],"container-title":["Arthroplasty Today"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352344122000760?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352344122000760?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T18:08:57Z","timestamp":1762452537000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352344122000760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":29,"alternative-id":["S2352344122000760"],"URL":"https:\/\/doi.org\/10.1016\/j.artd.2022.03.007","relation":{},"ISSN":["2352-3441"],"issn-type":[{"value":"2352-3441","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Novel Mobile App-Based Neuromuscular Electrical Stimulation Therapy for Improvement of Knee Pain, Stiffness, and Function in Knee Osteoarthritis: A Randomized Trial","name":"articletitle","label":"Article Title"},{"value":"Arthroplasty Today","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.artd.2022.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc. on behalf of The American Association of Hip and Knee Surgeons.","name":"copyright","label":"Copyright"}]}}