{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:39:16Z","timestamp":1762875556305},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.arteri.2013.07.006","type":"journal-article","created":{"date-parts":[[2013,9,14]],"date-time":"2013-09-14T11:31:10Z","timestamp":1379158270000},"page":"155-163","source":"Crossref","is-referenced-by-count":18,"title":["Consecuci\u00f3n del objetivo terap\u00e9utico del colesterol de las lipoprote\u00ednas de baja densidad en las unidades de l\u00edpidos y riesgo vascular de la Sociedad Espa\u00f1ola de Arteriosclerosis"],"prefix":"10.1016","volume":"25","author":[{"given":"Juan","family":"Pedro-Botet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 M.","family":"Mostaza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Pint\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 R.","family":"Banegas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arteri.2013.07.006_bib0005","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1093\/eurheartj\/ehs092","volume":"33","author":"Perk","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.arteri.2013.07.006_bib0010","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0140-6736(04)17018-9","article-title":"Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study","volume":"364","author":"Yusuf","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.arteri.2013.07.006_bib0015","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1157\/13113930","article-title":"Riesgo coronario atribuible a los factores de riesgo cardiovascular en poblaci\u00f3n espa\u00f1ola","volume":"60","author":"Medrano","year":"2007","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.arteri.2013.07.006_bib0020","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/S0140-6736(05)67394-1","article-title":"Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins","volume":"366","author":"Baigent","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.arteri.2013.07.006_bib0025","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0140-6736(08)60104-X","article-title":"Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: A meta-analysis","volume":"371","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.arteri.2013.07.006_bib0030","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1016\/S0140-6736(10)61350-5","article-title":"Efficacy and safety of more intensive lowering of LDLcholesterol: A meta-analysis of data from 170,000 participants in 26 randomised trials","volume":"376","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.arteri.2013.07.006_bib0035","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S0140-6736(09)60330-5","article-title":"Cardiovascular prevention guidelines in daily practice: A comparison of EUROASPIRE I, II, and III surveys in eight European countries","volume":"373","author":"Kotseva","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.arteri.2013.07.006_bib0040","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.atherosclerosis.2005.11.011","article-title":"The gap between dyslipidemia control perceived by physicians and objective control patterns in Spain","volume":"188","author":"Banegas","year":"2006","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.arteri.2013.07.006_bib0045","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.recesp.2011.04.019","article-title":"Tratamiento y control de los factores de riesgo seg\u00fan el riesgo coronario en la poblaci\u00f3n espa\u00f1ola del estudio DARIOS","volume":"64","author":"Baena-D\u00edez","year":"2011","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.arteri.2013.07.006_bib0050","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.recesp.2010.10.030","article-title":"Prevalencia y caracter\u00edsticas de la dislipemia en pacientes en prevenci\u00f3n primaria y secundaria tratados con estatinas en Espa\u00f1a. Estudio DYSIS-Espa\u00f1a","volume":"64","author":"Gonz\u00e1lez-Juanatey","year":"2011","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.arteri.2013.07.006_bib0055","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.recesp.2011.05.022","article-title":"Magnitud y caracter\u00edsticas del riesgo residual lip\u00eddico en pacientes con antecedentes de revascularizaci\u00f3n coronaria: Estudio ICP-Bypass","volume":"64","author":"Gonz\u00e1lez-Juanatey","year":"2011","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.arteri.2013.07.006_bib0060","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.recesp.2012.02.005","article-title":"Magnitud y manejo de la hipercolesterolemia en la poblaci\u00f3n adulta de Espa\u00f1a, 2008-2010: el estudio ENRICA","volume":"65","author":"Guallar-Castill\u00f3n","year":"2012","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.arteri.2013.07.006_bib0065","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.rce.2012.07.003","article-title":"Prevalencia de colesterolLDL inadecuado en pacientes con enfermedad coronaria y\/o diabetes mellitus tipo2","volume":"212","author":"P\u00e9rez de Isla","year":"2012","journal-title":"Rev Clin Esp"},{"key":"10.1016\/j.arteri.2013.07.006_bib0070","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1093\/eurheartj\/ehm316","volume":"28","author":"Graham","year":"2007","journal-title":"Eur Heart J"},{"issue":"Suppl. 3","key":"10.1016\/j.arteri.2013.07.006_bib0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/00019053-200422003-00002","article-title":"Current lipid management and low cholesterol goal attainment in common daily practice in Spain. The REALITY Study","volume":"22","author":"Garc\u00eda Ruiz","year":"2004","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.arteri.2013.07.006_bib0080","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1157\/13100222","article-title":"Efecto de una intervenci\u00f3n global sobre el control integral de m\u00faltiples factores de riesgo en pacientes con alto o muy alto riesgo cardiovascular. Estudio CIFARC 2","volume":"207","author":"De la Pe\u00f1a Fern\u00e1ndez","year":"2007","journal-title":"Rev Clin Esp"},{"key":"10.1016\/j.arteri.2013.07.006_bib0085","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/S0300-8932(10)70269-4","article-title":"Inercia terap\u00e9utica en el manejo extrahospitalario de la dislipemia en pacientes con cardiopat\u00eda isqu\u00e9mica. Estudio INERCIA","volume":"63","author":"L\u00e1zaro","year":"2010","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.arteri.2013.07.006_bib0090","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1056\/NEJM199908123410707","article-title":"Drug treatment of lipid disorders","volume":"341","author":"Knopp","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arteri.2013.07.006_bib0095","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.amjcard.2009.08.651","article-title":"Meta-analysis of comparative efficacy of increasing dose of atorvastatin versus rosuvastatin versus simvastatin on lowering levels of atherogenic lipids (from VOYAGER)","volume":"105","author":"Nicholls","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.arteri.2013.07.006_bib0100","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.ahj.2003.10.004","article-title":"Effects of switching statins on achievement of lipid goals: Measuring effective reductions in cholesterol using rosuvastatin therapy (MERCURY I) study","volume":"147","author":"Schuster","year":"2004","journal-title":"Am Heart J"},{"key":"10.1016\/j.arteri.2013.07.006_bib0105","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1056\/NEJMsa0806603","article-title":"Analyses of cancer data from three ezetimibe trials","volume":"359","author":"Peto","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arteri.2013.07.006_bib0110","doi-asserted-by":"crossref","first-page":"622","DOI":"10.7326\/0003-4819-151-9-200911030-00144","article-title":"Systematic review: Comparative effectiveness and harms of combination therapy and monotherapy for dyslipidemia","volume":"151","author":"Sharma","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.arteri.2013.07.006_bib0115","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1056\/NEJMoa0804602","article-title":"Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis","volume":"359","author":"Rosseb\u00f8","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arteri.2013.07.006_bib0120","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1016\/S0140-6736(11)60739-3","article-title":"The effects of lowering LDLcholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): A randomised placebo-controlled trial","volume":"377","author":"Baigent","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.arteri.2013.07.006_bib0125","first-page":"415","article-title":"Ezetimibe therapy: Mechanism of action and clinical update","volume":"8","author":"Phan","year":"2012","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.arteri.2013.07.006_bib0130","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1185\/03007995.2011.571239","article-title":"Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: Systematic review and meta-analysis","volume":"27","author":"Mikhailidis","year":"2011","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.arteri.2013.07.006_bib0135","series-title":"Informe SEA 2007","article-title":"Las enfermedades cardiovasculares y sus factores de riesgo en Espa\u00f1a: hechos y cifras","author":"Villar","year":"2007"},{"key":"10.1016\/j.arteri.2013.07.006_bib0140","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1161\/CIRCULATIONAHA.108.838466","article-title":"Lipid Treatment Assessment Project 2: A multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals","volume":"120","author":"Waters","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.arteri.2013.07.006_bib0145","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.rce.2012.07.005","article-title":"El largo trecho para llegar a los objetivos en el tratamiento de las dislipemias","volume":"212","author":"Pint\u00f3","year":"2012","journal-title":"Rev Clin Esp"}],"container-title":["Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0214916813000764?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0214916813000764?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,24]],"date-time":"2019-07-24T03:38:11Z","timestamp":1563939491000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0214916813000764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0214916813000764"],"URL":"https:\/\/doi.org\/10.1016\/j.arteri.2013.07.006","relation":{},"ISSN":["0214-9168"],"issn-type":[{"value":"0214-9168","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]}}}