{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T20:51:58Z","timestamp":1789419118691,"version":"build-2803163510"},"reference-count":18,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1016\/j.arteri.2014.09.003","type":"journal-article","created":{"date-parts":[[2014,12,10]],"date-time":"2014-12-10T21:42:54Z","timestamp":1418247774000},"page":"144-147","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["El continuo de la EPOC y riesgo cardiovascular: una hip\u00f3tesis global de la enfermedad"],"prefix":"10.1016","volume":"27","author":[{"given":"Carlos Alberto","family":"N\u00e1zara Otero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adolfo","family":"Baloira Villar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arteri.2014.09.003_bib0005","series-title":"Recomendaciones Semergen-EPOC","author":"Quintano Jim\u00e9nez","year":"2012"},{"key":"10.1016\/j.arteri.2014.09.003_bib0010","series-title":"Estrategias de manejo y criterios de derivaci\u00f3n de pacientes con EPOC: gu\u00eda pr\u00e1ctica basada en GesEPOC, atenci\u00f3n primaria-especializada","first-page":"3","author":"Baloira Villar","year":"2013"},{"key":"10.1016\/j.arteri.2014.09.003_bib0015","first-page":"7","article-title":"EPOC, una enfermedad en evoluci\u00f3n","volume":"671","author":"Trigueros Carrero","year":"2013","journal-title":"Tiempos M\u00e9dicos"},{"key":"10.1016\/j.arteri.2014.09.003_bib0020","first-page":"4","article-title":"Paciente con enfermedad pulmonar obstructiva cr\u00f3nica y elevado consumo de recursos sanitarios","volume":"4","author":"Garc\u00eda Polo","year":"2013","journal-title":"PubEPOC"},{"key":"10.1016\/j.arteri.2014.09.003_bib0025","series-title":"Enfermedad pulmonar obstructiva cr\u00f3nica (EPOC)","first-page":"18","article-title":"Epidemiolog\u00eda, factores de riesgo y nuevas tendencias en su historia natural","author":"S\u00e1nchez Rodr\u00edguez","year":"2004"},{"key":"10.1016\/j.arteri.2014.09.003_bib0030","series-title":"Enfermedad pulmonar obstructiva cr\u00f3nica (EPOC)","first-page":"225","article-title":"L\u00edneas actuales de la investigaci\u00f3n en la EPOC","author":"Alfageme","year":"2004"},{"key":"10.1016\/j.arteri.2014.09.003_bib0035","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1002\/emmm.201100627","article-title":"Emerging genetics of COPD","volume":"4","author":"Berndt","year":"2012","journal-title":"EMBO Mol Med"},{"key":"10.1016\/j.arteri.2014.09.003_bib0040","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.semerg.2012.04.005","article-title":"Consenso sobre la atenci\u00f3n integral de las agudizaciones en la enfermedad pulmonar obstructiva cr\u00f3nica (ATINA-EPOC). Parte V","volume":"39","author":"Arnedillo Mu\u00f1oz","year":"2013","journal-title":"Semergen"},{"key":"10.1016\/j.arteri.2014.09.003_bib0045","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.semerg.2012.04.006","article-title":"Consenso sobre la atenci\u00f3n integral de las agudizaciones en la enfermedad pulmonar obstructiva cr\u00f3nica (ATINA-EPOC). Parte VI","volume":"39","author":"Arnedillo Mu\u00f1oz","year":"2013","journal-title":"Semergen"},{"key":"10.1016\/j.arteri.2014.09.003_bib0050","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.semerg.2012.04.007","article-title":"Consenso sobre la atenci\u00f3n integral de las agudizaciones en la enfermedad pulmonar obstructiva cr\u00f3nica (ATINA-EPOC). Parte VII","volume":"39","author":"Arnedillo Mu\u00f1oz","year":"2013","journal-title":"Semergen"},{"issue":"Supl","key":"10.1016\/j.arteri.2014.09.003_bib0055","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0014-2565(11)70006-6","article-title":"Impacto de las exacerbaciones en la evoluci\u00f3n de la EPOC","volume":"2","author":"Soler-Catalu\u00f1a","year":"2011","journal-title":"Rev Clin Esp"},{"key":"10.1016\/j.arteri.2014.09.003_bib0060","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1378\/chest.12-0930","article-title":"The influence of cigarette smoking on viral infections","volume":"143","author":"Bauer","year":"2013","journal-title":"Chest"},{"key":"10.1016\/j.arteri.2014.09.003_bib0065","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1186\/1475-2840-11-132","article-title":"Chronic obstrutive pulmonary disease and glucose metabolism: A bitter sweet symphony","volume":"11","author":"Mittakhimov","year":"2012","journal-title":"Cardiovasc Diabetol"},{"issue":"Supl","key":"10.1016\/j.arteri.2014.09.003_bib0070","first-page":"53","article-title":"Ansiedad y depresi\u00f3n en la EPOC","volume":"1","author":"L\u00f3pez Garc\u00eda","year":"2007","journal-title":"Rev Clin Esp"},{"key":"10.1016\/j.arteri.2014.09.003_bib0075","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0300-2896(09)72862-5","article-title":"Disfunci\u00f3n muscular esquel\u00e9tica en la EPOC","volume":"45","author":"Gea","year":"2009","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.arteri.2014.09.003_bib0080","first-page":"38","article-title":"Osteoporosis en la enfermedad pulmonar obstructiva cr\u00f3nica","volume":"1","author":"Saab","year":"2004","journal-title":"Revista Argentina de Medicina Respiratoria"},{"key":"10.1016\/j.arteri.2014.09.003_bib0085","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S1699-258X(05)72706-6","article-title":"Osteoporosis en el var\u00f3n con enfermedad pulmonar obstructiva cr\u00f3nica. Utilidad de la densitometr\u00eda de falange (AccuDEXA) como m\u00e9todo de cribado diagn\u00f3stico.","volume":"1","author":"Casado","year":"2005","journal-title":"Reumatol Clin"},{"key":"10.1016\/j.arteri.2014.09.003_bib0090","series-title":"Abordaje precoz de la EPOC","first-page":"1","author":"Cimas","year":"2010"}],"container-title":["Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0214916814001296?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0214916814001296?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T03:20:19Z","timestamp":1538018419000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0214916814001296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S0214916814001296"],"URL":"https:\/\/doi.org\/10.1016\/j.arteri.2014.09.003","relation":{},"ISSN":["0214-9168"],"issn-type":[{"value":"0214-9168","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"El continuo de la EPOC y riesgo cardiovascular: una hip\u00f3tesis global de la enfermedad","name":"articletitle","label":"Article Title"},{"value":"Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arteri.2014.09.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Sociedad Espa\u00f1ola de Arteriosclerosis. Published by Elsevier Espa\u00f1a, S.L. All rights reserved.","name":"copyright","label":"Copyright"}]}}