{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:47:37Z","timestamp":1762876057632},"reference-count":32,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.arteri.2018.11.004","type":"journal-article","created":{"date-parts":[[2019,1,31]],"date-time":"2019-01-31T04:33:56Z","timestamp":1548909236000},"page":"93-100","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Una nueva estrategia para alcanzar los niveles objetivos de colesterol LDL tras un s\u00edndrome coronario agudo"],"prefix":"10.1016","volume":"31","author":[{"given":"N\u00faria","family":"Ribas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Llu\u00eds","family":"Recasens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edctor","family":"Baz\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Pedro-Botet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Elosua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"Mart\u00ed-Almor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arteri.2018.11.004_bib0165","unstructured":"European Cardiovascular Disease Statistics 2017 \u2013EHN\u2013 European Heart Network; 2017 [consultado 20 Sep 2017]. Disponible en: http:\/\/www.ehnheart.org\/cvd-statistics.html"},{"key":"10.1016\/j.arteri.2018.11.004_bib0170","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1016\/S0140-6736(10)61350-5","article-title":"Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170,000 participants in 26 randomised trials","volume":"376","author":"Baigent","year":"2010","journal-title":"Lancet."},{"key":"10.1016\/j.arteri.2018.11.004_bib0175","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0140-6736(12)60367-5","article-title":"The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials","volume":"380","author":"Mihaylova","year":"2012","journal-title":"Lancet."},{"key":"10.1016\/j.arteri.2018.11.004_bib0180","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.jacc.2014.02.615","article-title":"Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: A meta-analysis of statin trials","volume":"64","author":"Boekholdt","year":"2014","journal-title":"J Am Coll Cardiol."},{"key":"10.1016\/j.arteri.2018.11.004_bib0185","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1001\/jama.2016.13985","article-title":"Association between lowering LDL-C and cardiovascular risk reduction among different therapeutic interventions: A systematic review and meta-analysis","volume":"316","author":"Silverman","year":"2016","journal-title":"JAMA."},{"key":"10.1016\/j.arteri.2018.11.004_bib0190","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.ahj.2017.08.005","article-title":"Lipid management in contemporary community practice: Results from the Provider Assessment of Lipid Management (PALM) Registry","volume":"193","author":"Navar","year":"2017","journal-title":"Am Heart J."},{"key":"10.1016\/j.arteri.2018.11.004_bib0195","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1177\/2047487315569401","article-title":"EUROASPIRE IV: A European Society of Cardiology survey on the lifestyle, risk factor and therapeutic management of coronary patients from 24 European countries","volume":"23","author":"Kotseva","year":"2016","journal-title":"Eur J Prev Cardiol"},{"key":"10.1016\/j.arteri.2018.11.004_bib0200","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s12872-017-0493-6","article-title":"Secondary prevention strategies after an acute ST-segment elevation myocardial infarction in the AMI code era: beyond myocardial mechanical reperfusion","volume":"17","author":"Ribas","year":"2017","journal-title":"BMC Cardiovasc Disord."},{"key":"10.1016\/j.arteri.2018.11.004_bib0205","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.recesp.2016.02.013","article-title":"Degree of lipid control in patients with coronary heart disease and measures adopted by phisicians. REPAR Study","volume":"69","author":"Galve","year":"2016","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.arteri.2018.11.004_bib0210","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/S0300-8932(10)70269-4","article-title":"Therapeutic inertia in the outpatient management of dyslipidemia in patients with ischemic heart disease. The Inertia Study","volume":"63","author":"L\u00e1zaro","year":"2010","journal-title":"Rev Esp Cardiol."},{"key":"10.1016\/j.arteri.2018.11.004_bib0215","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1001\/jama.285.13.1711","article-title":"Effects of atorvastatin on early recurrent ischemic events in acute coronary s\u00edndromes: the MIRACL study: A randomized trial","volume":"285","author":"Schwart","year":"2001","journal-title":"JAMA."},{"key":"10.1016\/j.arteri.2018.11.004_bib0220","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1001\/jama.292.11.1307","article-title":"Early intensive vs delayed conservative simvastatin strategy in patients with acute coronary syndromes: Phase Z of the A to Z trial","volume":"292","author":"De Lemos","year":"2004","journal-title":"JAMA."},{"key":"10.1016\/j.arteri.2018.11.004_bib0225","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1157\/13070853","article-title":"Planificaci\u00f3n del tratamiento de la hipercolesterolemia orientada a la obtenci\u00f3n de objetivos","volume":"124","author":"Masana","year":"2005","journal-title":"Med Clin (Barc)."},{"key":"10.1016\/j.arteri.2018.11.004_bib0230","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.medcli.2010.02.025","article-title":"Actualizaci\u00f3n de las tablas de planificaci\u00f3n terap\u00e9utica de la hipercolesterolemia","volume":"135","author":"Masana","year":"2010","journal-title":"Med Clin (Barc)."},{"key":"10.1016\/j.arteri.2018.11.004_bib0235","first-page":"138","article-title":"Actualizaci\u00f3n de las tablas de planificaci\u00f3n terap\u00e9utica hipocolesterolemiante orientada a la obtenci\u00f3n de los objetivos","volume":"27","author":"Masana","year":"2015","journal-title":"Clin Invest Arterioscl."},{"key":"10.1016\/j.arteri.2018.11.004_bib0240","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1471-2296-4-18","article-title":"Statins in hypercholesterolemia: A dose-specific meta-analysis of lipid changes in randomized, double blind trials","volume":"4","author":"Edwards","year":"2003","journal-title":"BMC Fam Pract"},{"key":"10.1016\/j.arteri.2018.11.004_bib0245","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/S0002-9149(97)00965-X","article-title":"Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (The CURVES Study)","volume":"81","author":"Jones","year":"1998","journal-title":"Am J Cardiol."},{"key":"10.1016\/j.arteri.2018.11.004_bib0250","unstructured":"Gu\u00edas de buena pr\u00e1ctica cl\u00ednica de dislipemias, 2.a edici\u00f3n actualizada. 2009 [consultado 1 Sep 2017]. Disponible en: http:\/\/www.cgcom.es\/sites\/default\/files\/guia_dislipemias_2_edicion.pdf"},{"key":"10.1016\/j.arteri.2018.11.004_bib0255","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.atherosclerosis.2013.09.029","article-title":"Pilot study to validate a computer-based clinical decision support system for dyslipidemia treatment (HTE-DLP)","volume":"231","author":"Zamora","year":"2013","journal-title":"Atherosclerosis."},{"key":"10.1016\/j.arteri.2018.11.004_bib0260","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.atherosclerosis.2015.03.002","article-title":"IMPROVE-IT clinical implications. Should the \u201chigh-intensity cholesterol-lowering therapy\u201d strategy replace the \u201chigh-intensity statin therapy\u201d?","volume":"240","author":"Masana","year":"2015","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.arteri.2018.11.004_bib0265","first-page":"1","article-title":"2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation","volume":"00","author":"Ib\u00e1\u00f1ez","year":"2017","journal-title":"Eur Heart J"},{"key":"10.1016\/j.arteri.2018.11.004_bib0270","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/eurheartj\/ehv320","volume":"37","author":"Roffi","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.arteri.2018.11.004_bib0275","first-page":"13","article-title":"Control lip\u00eddico en pacientes con enfermedad coronaria del \u00c1rea de Salud de C\u00e1ceres (Espa\u00f1a): estudio LIPICERES","volume":"29","author":"G\u00f3mez-Barrado","year":"2017","journal-title":"Clin Investig Arterioscler."},{"key":"10.1016\/j.arteri.2018.11.004_bib0280","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.1093\/eurheartj\/ehw272","article-title":"2016\/EAS Guidelines for the management of dyslipidaemias","volume":"37","author":"Catapano","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.arteri.2018.11.004_bib0285","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1056\/NEJMoa1410489","article-title":"Ezetimibe added to statin therapy after acute coronary syndromes","volume":"372","author":"Cannon","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arteri.2018.11.004_bib0290","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1002\/clc.22343","article-title":"Is high-intensity statin therapy associated with lower statin adherence compared with low- to moderate-intensity statin therapy? Implications of the 2013 American College of Cardiology\/American Heart Association Cholesterol Management Guidelines","volume":"37","author":"Virani","year":"2014","journal-title":"Clin Cardiol."},{"key":"10.1016\/j.arteri.2018.11.004_bib0295","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1001\/jama.291.18.2243","article-title":"Drug treatment of hyperlipidemia in women","volume":"291","author":"Walsh","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.arteri.2018.11.004_bib0300","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/S0140-6736(14)61368-4","article-title":"Efficacy and safety of LDL-lowering therapy among men and women: Meta-analysis of individual data from 174,000 participants in 27 randomised trials","volume":"385","author":"Fulcher","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.arteri.2018.11.004_bib0305","doi-asserted-by":"crossref","first-page":"511","DOI":"10.2217\/fca.15.46","volume":"11","author":"Kritharides","year":"2015","journal-title":"Future Cardiol"},{"key":"10.1016\/j.arteri.2018.11.004_bib0310","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s12875-016-0505-0","article-title":"Low use of statins for secondary prevention in primary care: A survey in a northern Swedish population","volume":"17","author":"Nilssom","year":"2016","journal-title":"BMC Fam Pract"},{"key":"10.1016\/j.arteri.2018.11.004_bib0315","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.2174\/0929867324666161118094711","article-title":"Treatment and response to statins: Gender-related differences","volume":"24","author":"Raparelli","year":"2017","journal-title":"Curr Med Chem."},{"key":"10.1016\/j.arteri.2018.11.004_bib0320","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.phrs.2016.12.027","article-title":"Gender related differences in treatment and response to statins in primary and secondary cardiovascular prevention: The never-ending debate","volume":"117","author":"Cangemi","year":"2017","journal-title":"Pharmacol Res."}],"container-title":["Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0214916818301438?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0214916818301438?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T20:54:39Z","timestamp":1560027279000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0214916818301438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["S0214916818301438"],"URL":"https:\/\/doi.org\/10.1016\/j.arteri.2018.11.004","relation":{},"ISSN":["0214-9168"],"issn-type":[{"value":"0214-9168","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Una nueva estrategia para alcanzar los niveles objetivos de colesterol LDL tras un s\u00edndrome coronario agudo","name":"articletitle","label":"Article Title"},{"value":"Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arteri.2018.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Espa\u00f1a, S.L.U. on behalf of Sociedad Espa\u00f1ola de Arteriosclerosis.","name":"copyright","label":"Copyright"}]}}