{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T04:16:27Z","timestamp":1783052187628,"version":"3.54.6"},"reference-count":26,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","arthroplastyjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.arth.2015.12.042","type":"journal-article","created":{"date-parts":[[2016,3,27]],"date-time":"2016-03-27T07:01:34Z","timestamp":1459062094000},"page":"1437-1441","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis"],"prefix":"10.1016","volume":"31","author":[{"given":"Snir","family":"Heller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Secrist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alisina","family":"Shahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia F.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javad","family":"Parvizi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.arth.2015.12.042_bib1","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.arth.2012.08.004","article-title":"Safety and efficacy of multimodal thromboprophylaxis following total knee arthroplasty: a comparative study of preferential aspirin vs. routine coumadin chemoprophylaxis","volume":"28","author":"Gesell","year":"2013","journal-title":"J\u00a0Arthroplasty"},{"issue":"7","key":"10.1016\/j.arth.2015.12.042_bib2","doi-asserted-by":"crossref","first-page":"929","DOI":"10.2106\/00004623-200007000-00004","article-title":"A\u00a0meta-analysis of thromboembolic prophylaxis following elective total hip arthroplasty","volume":"82","author":"Freedman","year":"2000","journal-title":"J\u00a0Bone Joint Surg"},{"key":"10.1016\/j.arth.2015.12.042_bib3","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.otsr.2012.05.002","article-title":"Tranexamic acid reduces blood loss and financial cost in primary total hip and knee replacement surgery","volume":"98","author":"Irisson","year":"2012","journal-title":"Orthop Traumatol Surg Res"},{"key":"10.1016\/j.arth.2015.12.042_bib4","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jss.2013.08.020","article-title":"The use of tranexamic acid to reduce blood loss and\u00a0transfusion in major orthopedic surgery: a meta-analysis","volume":"186","author":"Huang","year":"2014","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.arth.2015.12.042_bib5","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s00590-014-1457-5","article-title":"Single perioperative dose of tranexamic acid in primary hip and knee arthroplasty","volume":"25","author":"George","year":"2015","journal-title":"Eur J Orthop Surg Traumatol"},{"issue":"3","key":"10.1016\/j.arth.2015.12.042_bib6","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/tme.12212","article-title":"The effectiveness and safety of tranexamic acid in total hip or knee arthroplasty: a meta-analysis of 2720 cases","volume":"25","author":"Wei","year":"2015","journal-title":"Transfus Med"},{"key":"10.1016\/j.arth.2015.12.042_bib7","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.2165\/00003495-199957060-00017","article-title":"Tranexamic acid: a review of its use in surgery and other indications","volume":"57","author":"Dunn","year":"1999","journal-title":"Drugs"},{"key":"10.1016\/j.arth.2015.12.042_bib8","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3109\/00365528709089756","article-title":"Clinical pharmacology of tranexamic acid","volume":"137","author":"Astedt","year":"1987","journal-title":"Scand J Gastroenterol Suppl"},{"key":"10.1016\/j.arth.2015.12.042_bib9","doi-asserted-by":"crossref","first-page":"g4829","DOI":"10.1136\/bmj.g4829","article-title":"Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety","volume":"349","author":"Poeran","year":"2014","journal-title":"BMJ"},{"issue":"21","key":"10.1016\/j.arth.2015.12.042_bib10","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1056\/NEJMoa1210384","article-title":"ASPIRE Investigators. Low-dose aspirin for preventing recurrent venous thromboembolism","volume":"367","author":"Brighton","year":"2012","journal-title":"N\u00a0Engl J Med"},{"issue":"3","key":"10.1016\/j.arth.2015.12.042_bib11","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1007\/s11999-013-3358-z","article-title":"Symptomatic pulmonary embolus after joint\u00a0arthroplasty: stratification of risk factors","volume":"472","author":"Parvizi","year":"2014","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"10.1016\/j.arth.2015.12.042_bib12","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s11999-011-2109-2","article-title":"Overdiagnosis of pulmonary embolism: evaluation of a hypoxia algorithm designed to avoid this catastrophic problem","volume":"470","author":"Winters","year":"2012","journal-title":"Clin Orthop Relat Res"},{"issue":"4","key":"10.1016\/j.arth.2015.12.042_bib13","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1046\/j.1537-2995.2003.00348.x","article-title":"Orthopedic Surgery Transfusion Hemoglobin European Overview (OSTHEO) study: blood management in elective knee and hip arthroplasty in Europe","volume":"43","author":"Rosencher","year":"2003","journal-title":"Transfusion"},{"key":"10.1016\/j.arth.2015.12.042_bib14","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1302\/0301-620X.96B8.33745","article-title":"A\u00a0systematic review and meta-analysis of the topical administration of tranexamic acid in total hip and knee replacement","volume":"96-B","author":"Alshryda","year":"2014","journal-title":"Bone Jt J"},{"key":"10.1016\/j.arth.2015.12.042_bib15","doi-asserted-by":"crossref","first-page":"132","DOI":"10.5435\/00124635-201003000-00002","article-title":"Antifibrinolytics in major orthopaedic surgery","volume":"18","author":"Eubanks","year":"2010","journal-title":"J\u00a0Am Acad Orthop Surg"},{"key":"10.1016\/j.arth.2015.12.042_bib16","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1056\/NEJMoa0802395","article-title":"A\u00a0comparison of aprotinin and lysine analogues in high-risk cardiac surgery","volume":"358","author":"Fergusson","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.arth.2015.12.042_bib17","first-page":"2764","article-title":"Venous thromboembolic disease after total hip and knee arthroplasty","volume":"90","author":"Haas","year":"2008","journal-title":"J\u00a0Bone Jt Surg"},{"key":"10.1016\/j.arth.2015.12.042_bib18","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.2106\/JBJS.I.00511","article-title":"American Academy of Orthopaedic Surgeons Clinical practice guideline on","volume":"91","author":"Johanson","year":"2009","journal-title":"J\u00a0Bone Jt Surg"},{"issue":"2","key":"10.1016\/j.arth.2015.12.042_bib19","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.arth.2014.08.022","article-title":"Venous thromboembolism and mortality associated with tranexamic acid use during total hip and knee arthroplasty","volume":"30","author":"Duncan","year":"2015","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2015.12.042_bib20","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1093\/bja\/aeu078","article-title":"Antifibrinolytic agents in current anaesthetic practice: use of tranexamic acid in lower limb arthroplasty","volume":"112","author":"Mu\u00f1oz","year":"2014","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.arth.2015.12.042_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12959-015-0063-z","article-title":"Should lifelong anticoagulation for unprovoked venous thromboembolism be revisited?","volume":"13","author":"Moodley","year":"2015","journal-title":"Thromb J"},{"issue":"21","key":"10.1016\/j.arth.2015.12.042_bib22","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1056\/NEJMoa1114238","article-title":"Aspirin for preventing the recurrence of venous thromboembolism","volume":"366","author":"Becattini","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.arth.2015.12.042_bib23","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.thromres.2008.09.015","article-title":"Use of antifibrinolytic therapy to reduce transfusion in patients undergoing orthopedic surgery: a systematic review of randomized trials","volume":"123","author":"Kagoma","year":"2009","journal-title":"Thromb Res"},{"key":"10.1016\/j.arth.2015.12.042_bib24","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1302\/0301-620X.93B1.24984","article-title":"Systematic review and meta-analysis of the use of tranexamic acid in total hip replacement","volume":"93-B","author":"Sukeik","year":"2011","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2015.12.042_bib25","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.jss.2013.03.099","article-title":"A\u00a0meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty","volume":"184","author":"Tan","year":"2013","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.arth.2015.12.042_bib26","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/s11999-012-2488-z","article-title":"Low risk of thromboembolic complications with tranexamic acid after primary total hip and knee arthroplasty","volume":"471","author":"Gillette","year":"2013","journal-title":"Clin Orthop"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540316000097?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540316000097?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T01:58:41Z","timestamp":1536890321000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883540316000097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S0883540316000097"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2015.12.042","relation":{},"ISSN":["0883-5403"],"issn-type":[{"value":"0883-5403","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2015.12.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}