{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T03:14:34Z","timestamp":1788146074982,"version":"build-2803163510"},"reference-count":40,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","arthroplastyjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.arth.2016.05.043","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T20:20:07Z","timestamp":1464726007000},"page":"2856-2861","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"title":["A Randomized, Clinical Trial of Preadmission Chlorhexidine Skin Preparation for Lower Extremity Total Joint Arthroplasty"],"prefix":"10.1016","volume":"31","author":[{"given":"Bhaveen H.","family":"Kapadia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randa K.","family":"Elmallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Mont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.arth.2016.05.043_bib1","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.ajic.2004.10.001","article-title":"National Nosocomial Infections Surveillance (NNIS) system report, data summary from January 1992 through June 2004, issued October 2004","volume":"32","year":"2004","journal-title":"Am J Infect Control"},{"issue":"2","key":"10.1016\/j.arth.2016.05.043_bib2","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s11999-014-3780-x","article-title":"The Otto Aufranc Award: modifiable versus nonmodifiable risk factors for infection after hip arthroplasty","volume":"473","author":"Maoz","year":"2015","journal-title":"Clin Orthop Relat Res"},{"issue":"9","key":"10.1016\/j.arth.2016.05.043_bib3","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1016\/j.arth.2014.04.013","article-title":"Management of periprosthetic joint infection after total hip arthroplasty using a custom made articulating spacer (CUMARS); the Exeter experience","volume":"29","author":"Tsung","year":"2014","journal-title":"J\u00a0Arthroplasty"},{"issue":"8","key":"10.1016\/j.arth.2016.05.043_bib4","doi-asserted-by":"crossref","first-page":"640","DOI":"10.2106\/JBJS.L.01639","article-title":"Variation in hospital-level risk-standardized complication rates following elective primary total hip and knee arthroplasty","volume":"96","author":"Bozic","year":"2014","journal-title":"J\u00a0Bone Joint Surg Am"},{"issue":"2","key":"10.1016\/j.arth.2016.05.043_bib5","first-page":"105","article-title":"Periprosthetic joint infection: modern aspects of prevention, diagnosis, and treatment","volume":"28","author":"Frank","year":"2015","journal-title":"J\u00a0Knee Surg"},{"issue":"1","key":"10.1016\/j.arth.2016.05.043_bib6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s11999-013-3029-0","article-title":"Targeted use of vancomycin as perioperative prophylaxis reduces periprosthetic joint infection in revision TKA","volume":"472","author":"Liu","year":"2014","journal-title":"Clin Orthop Relat Res"},{"issue":"3","key":"10.1016\/j.arth.2016.05.043_bib7","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1741-6787.2010.00201.x","article-title":"Searching for evidence regarding using preoperative disinfection showers to prevent surgical site infections: a systematic review","volume":"8","author":"Jakobsson","year":"2011","journal-title":"Worldviews Evid Based Nurs"},{"issue":"6 Suppl","key":"10.1016\/j.arth.2016.05.043_bib8","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.arth.2010.04.011","article-title":"Periprosthetic joint infection: the economic impact of methicillin-resistant infections","volume":"25","author":"Parvizi","year":"2010","journal-title":"J\u00a0Arthroplasty"},{"issue":"4","key":"10.1016\/j.arth.2016.05.043_bib9","doi-asserted-by":"crossref","first-page":"780","DOI":"10.2106\/00004623-200704000-00012","article-title":"Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030","volume":"89","author":"Kurtz","year":"2007","journal-title":"J\u00a0Bone Joint Surg Am"},{"issue":"1","key":"10.1016\/j.arth.2016.05.043_bib10","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1056\/NEJMoa0810988","article-title":"Chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis","volume":"362","author":"Darouiche","year":"2010","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1016\/j.arth.2016.05.043_bib11","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0196-6553(86)90095-7","article-title":"Operating room surveillance: a new approach in reducing hip and knee prosthetic wound infections","volume":"14","author":"Borst","year":"1986","journal-title":"Am J Infect Control"},{"issue":"4","key":"10.1016\/j.arth.2016.05.043_bib12","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1007\/s11999-010-1688-7","article-title":"Current concepts for clean air and total joint arthroplasty: laminar airflow and ultraviolet radiation: a systematic review","volume":"469","author":"Evans","year":"2011","journal-title":"Clin Orthop Relat Res"},{"issue":"9","key":"10.1016\/j.arth.2016.05.043_bib13","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.2106\/00004623-200709000-00007","article-title":"Ultraviolet lighting during orthopaedic surgery and the rate of infection","volume":"89","author":"Ritter","year":"2007","journal-title":"J\u00a0Bone Joint Surg Am"},{"issue":"12","key":"10.1016\/j.arth.2016.05.043_bib14","doi-asserted-by":"crossref","first-page":"e867","DOI":"10.1016\/j.ijid.2011.09.009","article-title":"Outcome of cefazolin prophylaxis for total knee arthroplasty at an institution with high prevalence of methicillin-resistant Staphylococcus aureus infection","volume":"15","author":"Song","year":"2011","journal-title":"Int J Infect Dis"},{"issue":"1-3","key":"10.1016\/j.arth.2016.05.043_bib15","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1574-6968.1992.tb05705.x","article-title":"The mechanism of action of chlorhexidine","volume":"100","author":"Kuyyakanond","year":"1992","journal-title":"FEMS Microbiol Lett"},{"issue":"3","key":"10.1016\/j.arth.2016.05.043_bib16","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.aorn.2010.01.016","article-title":"Reducing surgical site infections by bundling multiple risk reduction strategies and active surveillance","volume":"92","author":"Lipke","year":"2010","journal-title":"AORN J"},{"issue":"5","key":"10.1016\/j.arth.2016.05.043_bib17","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.aorn.2010.01.020","article-title":"Evidence for using chlorhexidine gluconate preoperative cleansing to reduce the risk of surgical site infection","volume":"92","author":"Edmiston","year":"2010","journal-title":"AORN J"},{"issue":"5","key":"10.1016\/j.arth.2016.05.043_bib18","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.aorn.2008.02.001","article-title":"Evaluation of the antimicrobial properties of an alcohol-free 2% chlorhexidine gluconate solution","volume":"87","author":"DeBaun","year":"2008","journal-title":"AORN J"},{"issue":"3","key":"10.1016\/j.arth.2016.05.043_bib19","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/NOR.0b013e3181a469db","article-title":"Presurgical skin preparation with a novel 2% chlorhexidine gluconate cloth reduces rates of surgical site infection in orthopaedic surgical patients","volume":"28","author":"Eiselt","year":"2009","journal-title":"Orthop Nurs"},{"issue":"3","key":"10.1016\/j.arth.2016.05.043_bib20","first-page":"160","article-title":"Topical antiseptics in healthcare","volume":"18","author":"Jackson","year":"2005","journal-title":"Clin Lab Sci"},{"issue":"2","key":"10.1016\/j.arth.2016.05.043_bib21","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jamcollsurg.2007.12.054","article-title":"Preoperative shower revisited: can high topical antiseptic levels be achieved on the skin surface before surgical admission?","volume":"207","author":"Edmiston","year":"2008","journal-title":"J\u00a0Am Coll Surg"},{"issue":"2","key":"10.1016\/j.arth.2016.05.043_bib22","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.ajic.2006.06.012","article-title":"Comparative of a new and innovative 2% chlorhexidine gluconate-impregnated cloth with 4% chlorhexidine gluconate as topical antiseptic for preparation of the skin prior to surgery","volume":"35","author":"Edmiston","year":"2007","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.arth.2016.05.043_bib23","series-title":"Surgical Site Infection (SSI) Event","year":"2015"},{"key":"10.1016\/j.arth.2016.05.043_bib24","article-title":"Prevention of periprosthetic joint infection","volume":"Vol. 41","author":"Potter GRNMT","year":"2014"},{"key":"10.1016\/j.arth.2016.05.043_bib25","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/00000542-194105000-00004","article-title":"Grading of patients for surgical procedures","volume":"2","author":"Saklad","year":"1941","journal-title":"Anesthesiology"},{"issue":"5","key":"10.1016\/j.arth.2016.05.043_bib26","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.ajic.2008.03.002","article-title":"CDC\/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting","volume":"36","author":"Horan","year":"2008","journal-title":"Am J Infect Control"},{"issue":"19","key":"10.1016\/j.arth.2016.05.043_bib27","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1001\/archinte.167.19.2066","article-title":"Chlorhexidine-based antiseptic solution vs alcohol-based povidone-iodine for central venous catheter care","volume":"167","author":"Mimoz","year":"2007","journal-title":"Arch Intern Med"},{"issue":"4","key":"10.1016\/j.arth.2016.05.043_bib28","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1086\/318145","article-title":"Prospective randomized trial of 10% povidone-iodine versus 0.5% tincture of chlorhexidine as cutaneous antisepsis for prevention of central venous catheter infection","volume":"31","author":"Humar","year":"2000","journal-title":"Clin Infect Dis"},{"issue":"4","key":"10.1016\/j.arth.2016.05.043_bib29","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0196-6553(93)90033-Z","article-title":"Efficacy evaluation of a 4% chlorhexidine gluconate as a full-body shower wash","volume":"21","author":"Paulson","year":"1993","journal-title":"Am J Infect Control"},{"issue":"8","key":"10.1016\/j.arth.2016.05.043_bib30","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1016\/j.arth.2011.03.014","article-title":"Preoperative screening\/decolonization for Staphylococcus aureus to prevent orthopedic surgical site infection: prospective cohort study with 2-year follow-up","volume":"26","author":"Rao","year":"2011","journal-title":"J\u00a0Arthroplasty"},{"issue":"6","key":"10.1016\/j.arth.2016.05.043_bib31","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1007\/s11999-008-0225-4","article-title":"A\u00a0preoperative decolonization protocol for staphylococcus aureus prevents orthopaedic infections","volume":"466","author":"Rao","year":"2008","journal-title":"Clin Orthop Relat Res"},{"issue":"9","key":"10.1016\/j.arth.2016.05.043_bib32","first-page":"2010","article-title":"Institutional prescreening for detection and eradication of methicillin-resistant Staphylococcus aureus in patients undergoing elective orthopaedic surgery","volume":"92","author":"Kim","year":"1820","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2016.05.043_bib33","first-page":"2010","article-title":"Staphylococcus aureus decolonization protocol decreases surgical site infections for total joint replacement","volume":"924518","author":"Hadley","year":"2010","journal-title":"Arthritis"},{"issue":"6","key":"10.1016\/j.arth.2016.05.043_bib34","doi-asserted-by":"crossref","first-page":"409","DOI":"10.7326\/0003-4819-148-6-200803180-00003","article-title":"Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitals","volume":"148","author":"Robicsek","year":"2008","journal-title":"Ann Intern Med"},{"issue":"10","key":"10.1016\/j.arth.2016.05.043_bib35","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.ajic.2010.06.005","article-title":"Daily chlorohexidine gluconate bathing with impregnated cloths results in statistically significant reduction in central line-associated bloodstream infections","volume":"38","author":"Dixon","year":"2010","journal-title":"Am J Infect Control"},{"issue":"3","key":"10.1016\/j.arth.2016.05.043_bib36","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1001\/archinte.166.3.306","article-title":"Chlorhexidine gluconate to cleanse patients in a medical intensive care unit: the effectiveness of source control to reduce the bioburden of vancomycin-resistant enterococci","volume":"166","author":"Vernon","year":"2006","journal-title":"Arch Intern Med"},{"issue":"19","key":"10.1016\/j.arth.2016.05.043_bib37","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1001\/archinte.167.19.2073","article-title":"Effectiveness of chlorhexidine bathing to reduce catheter-associated bloodstream infections in medical intensive care unit patients","volume":"167","author":"Bleasdale","year":"2007","journal-title":"Arch Intern Med"},{"issue":"7","key":"10.1016\/j.arth.2016.05.043_bib38","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1007\/s00264-010-1078-5","article-title":"Advance pre-operative chlorhexidine reduces the incidence of surgical site infections in knee arthroplasty","volume":"35","author":"Zywiel","year":"2011","journal-title":"Int Orthop"},{"issue":"3","key":"10.1016\/j.arth.2016.05.043_bib39","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.arth.2012.07.015","article-title":"Pre-admission cutaneous chlorhexidine preparation reduces surgical site infections in total hip arthroplasty","volume":"28","author":"Kapadia","year":"2013","journal-title":"J\u00a0Arthroplasty"},{"issue":"7","key":"10.1016\/j.arth.2016.05.043_bib40","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.arth.2013.02.026","article-title":"Economic evaluation of chlorhexidine cloths on healthcare costs due to surgical site infections following total knee arthroplasty","volume":"28","author":"Kapadia","year":"2013","journal-title":"J\u00a0Arthroplasty"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540316302224?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540316302224?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T10:59:13Z","timestamp":1600685953000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883540316302224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S0883540316302224"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2016.05.043","relation":{},"ISSN":["0883-5403"],"issn-type":[{"value":"0883-5403","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Randomized, Clinical Trial of Preadmission Chlorhexidine Skin Preparation for Lower Extremity Total Joint Arthroplasty","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2016.05.043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}