{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:35:12Z","timestamp":1761676512896,"version":"3.40.5"},"reference-count":57,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","arthroplastyjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.arth.2017.05.030","type":"journal-article","created":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T16:45:39Z","timestamp":1495471539000},"page":"3219-3227","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Osteoclasts in Periprosthetic Osteolysis: The Charnley Arthroplasty Revisited"],"prefix":"10.1016","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5469-2730","authenticated-orcid":false,"given":"Sebastian S.","family":"Mukka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6ran N.","family":"Andersson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kjell R.","family":"Hultenby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olof G.","family":"Sk\u00f6ldenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joakim P.","family":"Nordahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas M.","family":"Eisler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arth.2017.05.030_bib1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/00003086-200112000-00007","article-title":"Wear and periprosthetic osteolysis: the problem","author":"Harris","year":"2001","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2017.05.030_bib2","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/jor.1100140107","article-title":"Role of tumor necrosis factor alpha in particulate-induced bone resorption","volume":"14","author":"Algan","year":"1996","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.arth.2017.05.030_bib3","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.2106\/00004623-199608000-00008","article-title":"Increased levels of tumor necrosis factor-alpha and interleukin-6 protein and messenger RNA in human peripheral blood monocytes due to titanium particles","volume":"78","author":"Blaine","year":"1996","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2017.05.030_bib4","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1136\/ard.56.7.414","article-title":"Human arthroplasty derived macrophages differentiate into osteoclastic bone resorbing cells","volume":"56","author":"Sabokbar","year":"1997","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.arth.2017.05.030_bib5","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1126\/science.289.5484.1504","article-title":"Bone resorption by osteoclasts","volume":"289","author":"Teitelbaum","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.arth.2017.05.030_bib6","doi-asserted-by":"crossref","first-page":"185150","DOI":"10.1155\/2014\/185150","article-title":"The pathology of orthopedic implant failure is mediated by innate immune system cytokines","volume":"2014","author":"Landgraeber","year":"2014","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.arth.2017.05.030_bib7","first-page":"201","article-title":"The basic science of periprosthetic osteolysis","volume":"62","author":"Goodman","year":"2013","journal-title":"Instr Course Lect"},{"key":"10.1016\/j.arth.2017.05.030_bib8","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1302\/0301-620X.80B3.8158","article-title":"Cellular profile and cytokine production at prosthetic interfaces. Study of tissues retrieved from revised hip and knee replacements","volume":"80","author":"Goodman","year":"1998","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2017.05.030_bib9","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1302\/0301-620X.85B8.13311","article-title":"Imbalance of RANKL\/RANK\/OPG system in interface tissue in loosening of total hip replacement","volume":"85","author":"Mandelin","year":"2003","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2017.05.030_bib10","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1302\/0301-620X.78B4.0780641","article-title":"Periprosthetic bone resorption. Particles versus movement","volume":"78","author":"Aspenberg","year":"1996","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2017.05.030_bib11","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1302\/0301-620X.72B6.2246300","article-title":"Localised endosteal bone lysis in relation to the femoral components of cemented total hip arthroplasties","volume":"72","author":"Anthony","year":"1990","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2017.05.030_bib12","first-page":"239","article-title":"Cellular biology and biochemical mechanism of bone resorption. A review of recent developments on the formation, activation, and mode of action of osteoclasts","author":"Vaes","year":"1988","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2017.05.030_bib13","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1080\/000164700317362163","article-title":"Clodronate prevents prosthetic migration: a randomized radiostereometric study of 50 total knee patients","volume":"71","author":"Hilding","year":"2000","journal-title":"Acta Orthop Scand"},{"key":"10.1016\/j.arth.2017.05.030_bib14","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1080\/00016470412331294405","article-title":"An age-related medullary expansion can have implications for the long-term fixation of hip prostheses","volume":"75","author":"Ahlborg","year":"2004","journal-title":"Acta Orthop Scand"},{"key":"10.1016\/j.arth.2017.05.030_bib15","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1359\/jbmr.2001.16.1.79","article-title":"High-turnover periprosthetic bone remodeling and immature bone formation around loose cemented total hip joints","volume":"16","author":"Takagi","year":"2001","journal-title":"J\u00a0Bone Miner Res"},{"key":"10.1016\/j.arth.2017.05.030_bib16","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1002\/(SICI)1097-4636(1999)48:6<899::AID-JBM20>3.0.CO;2-E","article-title":"The characterization of macrophages and osteoclasts in tissues harvested from revised total hip prostheses","volume":"48","author":"Chun","year":"1999","journal-title":"J\u00a0Biomed Mater Res"},{"key":"10.1016\/j.arth.2017.05.030_bib17","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.2106\/00004623-199607000-00016","article-title":"Cellular biology of bone-resorbing cells","volume":"78","author":"Athanasou","year":"1996","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2017.05.030_bib18","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/0883-5403(94)90041-8","article-title":"Long-term results of Charnley arthroplasty. A 12-16-year follow-up study","volume":"9","author":"Garellick","year":"1994","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2017.05.030_bib19","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.2106\/00004623-198668070-00014","article-title":"Loosening of the femoral component after use of the\u00a0medullary-plug cementing technique. Follow-up note with a minimum five-year follow-up","volume":"68","author":"Harris","year":"1986","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2017.05.030_bib20","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1302\/0301-620X.54B1.61","article-title":"The long-term results of low-friction arthroplasty of the hip performed as a primary intervention","volume":"54","author":"Charnley","year":"1972","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2017.05.030_bib21","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1097\/00003086-200212000-00009","article-title":"Analysis of long-term cemented total hip arthroplasty retrievals","author":"Maloney","year":"2002","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2017.05.030_bib22","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1302\/0301-620X.74B3.1587883","article-title":"Improved cementing techniques and femoral component loosening in young patients with hip arthroplasty. A 12-year radiographic review","volume":"74","author":"Barrack","year":"1992","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2017.05.030_bib23","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1054\/arth.2001.24378","article-title":"Ultrasound for diagnosis of infection in revision total hip arthroplasty","volume":"16","author":"Eisler","year":"2001","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2017.05.030_bib24","first-page":"111","article-title":"Revision total hip arthroplasty with titanium ingrowth prosthesis and bone grafting for failed cemented femoral component loosening","author":"Gustilo","year":"1988","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2017.05.030_bib25","first-page":"17","article-title":"\u201cModes of failure\u201d of cemented stem-type femoral components: a radiographic analysis of loosening","author":"Gruen","year":"1979","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2017.05.030_bib26","first-page":"20","article-title":"Radiological demarcation of cemented sockets in total hip replacement","author":"DeLee","year":"1976","journal-title":"Clin Orthop Relat Res"},{"year":"1996","series-title":"Osteolysis","key":"10.1016\/j.arth.2017.05.030_bib27"},{"issue":"Pt 2","key":"10.1016\/j.arth.2017.05.030_bib28","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1042\/bj3210305","article-title":"Comparative studies of rat recombinant purple acid phosphatase and bone tartrate-resistant acid phosphatase","volume":"321","author":"Ek-Rylander","year":"1997","journal-title":"Biochem J"},{"key":"10.1016\/j.arth.2017.05.030_bib29","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1093\/oxfordjournals.jbchem.a022001","article-title":"Fluorescence microscopic demonstration of cathepsin K activity as the major lysosomal cysteine proteinase in osteoclasts","volume":"123","author":"Kamiya","year":"1998","journal-title":"J\u00a0Biochem (Tokyo)"},{"key":"10.1016\/j.arth.2017.05.030_bib30","first-page":"221","article-title":"The pathology of the joint tissues and\u00a0its clinical relevance in prosthesis failure","author":"Mirra","year":"1976","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2017.05.030_bib31","doi-asserted-by":"crossref","first-page":"849","DOI":"10.2106\/00004623-199274060-00006","article-title":"Periprosthetic bone loss in total hip arthroplasty. Polyethylene wear debris and the concept of the effective joint space","volume":"74","author":"Schmalzried","year":"1992","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2017.05.030_bib32","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0883-5403(97)90203-5","article-title":"Bone-membrane interface in aseptic loosening of total joint arthroplasties","volume":"12","author":"Atkins","year":"1997","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2017.05.030_bib33","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/jbmr.5650020617","article-title":"Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee","volume":"2","author":"Parfitt","year":"1987","journal-title":"J\u00a0Bone Miner Res"},{"key":"10.1016\/j.arth.2017.05.030_bib34","series-title":"Ham's histology","first-page":"1","author":"Cormack","year":"1987"},{"key":"10.1016\/j.arth.2017.05.030_bib35","series-title":"Basic histology","first-page":"1","author":"Junqueira","year":"1983"},{"key":"10.1016\/j.arth.2017.05.030_bib36","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1126\/science.289.5484.1501","article-title":"The osteoblast: a sophisticated fibroblast under central surveillance","volume":"289","author":"Ducy","year":"2000","journal-title":"Science"},{"year":"1994","series-title":"Ultrastructure of cells that have phagocytosed polyethylene particles in peri-implant tissue from revision arthroplasty. 40th Annual Meeting of the Orthopaedic Research Society","key":"10.1016\/j.arth.2017.05.030_bib37"},{"key":"10.1016\/j.arth.2017.05.030_bib38","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0169-6009(90)90058-N","article-title":"Bone histomorphometric reference values in 88 normal Italian subjects","volume":"11","author":"Ballanti","year":"1990","journal-title":"Bone Miner"},{"key":"10.1016\/j.arth.2017.05.030_bib39","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/8756-3282(94)00028-X","article-title":"Bone remodelling in human immunodeficiency virus-1-infected patients. A histomorphometric study","volume":"16","author":"Serrano","year":"1995","journal-title":"Bone"},{"key":"10.1016\/j.arth.2017.05.030_bib40","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S8756-3282(02)00847-5","article-title":"Morphological, histomorphometric, and microstructural alterations in human bone metastasis from breast carcinoma","volume":"31","author":"Vukmirovic-Popovic","year":"2002","journal-title":"Bone"},{"key":"10.1016\/j.arth.2017.05.030_bib41","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/8756-3282(94)90890-7","article-title":"Biologic, histologic and densitometric effects of oral risedronate on bone in patients with multiple myeloma","volume":"15","author":"Roux","year":"1994","journal-title":"Bone"},{"key":"10.1016\/j.arth.2017.05.030_bib42","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/8756-3282(91)90019-F","article-title":"Familial expansile osteolysis: a morphological, histomorphometric and serological study","volume":"12","author":"Dickson","year":"1991","journal-title":"Bone"},{"key":"10.1016\/j.arth.2017.05.030_bib43","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1302\/0301-620X.75B3.8496224","article-title":"Flanged acetabular components in cemented Charnley hip arthroplasty. Ten-year follow-up of 350 patients","volume":"75","author":"Hodgkinson","year":"1993","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2017.05.030_bib44","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/jbm.b.31638","article-title":"The relationship of polyethylene wear to particle size, distribution, and number: a possible factor explaining the risk of osteolysis after hip arthroplasty","volume":"94","author":"Gallo","year":"2010","journal-title":"J\u00a0Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.arth.2017.05.030_bib45","first-page":"3","article-title":"The origin of submicron polyethylene wear debris in total hip arthroplasty","author":"McKellop","year":"1995","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2017.05.030_bib46","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/jor.1100140318","article-title":"Bone formation and bone resorption in failed total joint arthroplasties: histomorphometric analysis with histochemical and immunohistochemical technique","volume":"14","author":"Kadoya","year":"1996","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.arth.2017.05.030_bib47","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1006\/excr.1999.4585","article-title":"Extensive clear zone and defective ruffled border formation in osteoclasts of osteopetrotic (ia\/ia) rats: implications for secretory function","volume":"251","author":"Reinholt","year":"1999","journal-title":"Exp Cel Res"},{"key":"10.1016\/j.arth.2017.05.030_bib48","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0945-053X(00)00052-4","article-title":"Osteoclast formation and resorption","volume":"19","author":"Lerner","year":"2000","journal-title":"Matrix Biol"},{"key":"10.1016\/j.arth.2017.05.030_bib49","first-page":"65","article-title":"Osteoclast formation and differentiation: an overview","volume":"59","author":"Soysa","year":"2012","journal-title":"J\u00a0Med Dent Sci"},{"key":"10.1016\/j.arth.2017.05.030_bib50","series-title":"Bone histomorphometry","first-page":"1","author":"Eriksen","year":"1993"},{"key":"10.1016\/j.arth.2017.05.030_bib51","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0169-6009(08)80211-5","article-title":"The expression of osteoclast markers on foreign body giant cells","volume":"27","author":"Kadoya","year":"1994","journal-title":"Bone Miner"},{"key":"10.1016\/j.arth.2017.05.030_bib52","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.bbrc.2004.10.024","article-title":"Dimer formation of receptor activator of nuclear factor kappaB induces incomplete osteoclast formation","volume":"325","author":"Iwamoto","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.arth.2017.05.030_bib53","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1302\/0301-620X.72B6.2246303","article-title":"Macrophages stimulate bone resorption when they phagocytose particles","volume":"72","author":"Murray","year":"1990","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2017.05.030_bib54","doi-asserted-by":"crossref","first-page":"R163","DOI":"10.1186\/ar752","article-title":"Osteoclast-independent bone resorption by fibroblast-like cells","volume":"5","author":"Pap","year":"2003","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.arth.2017.05.030_bib55","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/00003086-200009000-00024","article-title":"Synovial fluid from loose hip arthroplasties inhibits human osteoblasts","author":"Andersson","year":"2000","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2017.05.030_bib56","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1002\/jbm.a.32001","article-title":"Ultrahigh molecular weight polyethylene wear debris inhibits osteoprogenitor proliferation and differentiation in\u00a0vitro","volume":"89","author":"Chiu","year":"2009","journal-title":"J\u00a0Biomed Mater Res A"},{"key":"10.1016\/j.arth.2017.05.030_bib57","doi-asserted-by":"crossref","first-page":"5044","DOI":"10.1016\/j.biomaterials.2007.06.035","article-title":"Wear particles, periprosthetic osteolysis and the immune system","volume":"28","author":"Goodman","year":"2007","journal-title":"Biomaterials"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540317304692?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540317304692?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T07:51:03Z","timestamp":1719215463000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883540317304692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":57,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S0883540317304692"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2017.05.030","relation":{},"ISSN":["0883-5403"],"issn-type":[{"type":"print","value":"0883-5403"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Osteoclasts in Periprosthetic Osteolysis: The Charnley Arthroplasty Revisited","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2017.05.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}