{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:39:44Z","timestamp":1789180784210,"version":"build-2803163510"},"reference-count":15,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100012630","name":"Zimmer Biomet","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012630","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["arthroplastyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.arth.2019.12.010","type":"journal-article","created":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T20:23:45Z","timestamp":1576614225000},"page":"1355-1360","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Alpha Defensin: A Diagnostic Accuracy Depending on the Infection Definition Used"],"prefix":"10.1016","volume":"35","author":[{"given":"Maxime","family":"Huard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Detrembleur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herv\u00e9","family":"Poilvache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Pastor y Geels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u00efte","family":"Van Cauter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Driesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Cyr","family":"Yombi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"Neyt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Cornu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arth.2019.12.010_bib1","doi-asserted-by":"crossref","first-page":"923","DOI":"10.5301\/ijao.5000168","article-title":"Epidemiology and new developments in the diagnosis of prosthetic joint infection","volume":"35","author":"Corvec","year":"2012","journal-title":"Int J Artif Organs"},{"key":"10.1016\/j.arth.2019.12.010_bib2","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1056\/NEJMra040181","article-title":"Prosthetic-joint infections","volume":"351","author":"Zimmerli","year":"2004","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.arth.2019.12.010_bib3","doi-asserted-by":"crossref","first-page":"742","DOI":"10.2106\/JBJS.17.01005","article-title":"Alpha defensin lateral flow test for diagnosis of periprosthetic joint infection: not a screening but a confirmatory test","volume":"100","author":"Renz","year":"2018","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2019.12.010_bib4","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.arth.2014.03.009","article-title":"Consensus group on periprosthetic joint infection. Definition of periprosthetic joint infection","volume":"29","author":"Parvizi","year":"2014","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2019.12.010_bib5","doi-asserted-by":"crossref","first-page":"2992","DOI":"10.1007\/s11999-011-2102-9","article-title":"New definition for periprosthetic joint infection: from the workgroup of the musculoskeletal infection society","volume":"469","author":"Parvizi","year":"2011","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2019.12.010_bib6","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.arth.2018.02.078","article-title":"The 2018 definition of periprosthetic hip and knee infection: an evidence-based and validated criteria","volume":"33","author":"Parvizi","year":"2018","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2019.12.010_bib7","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1007\/s00167-017-4745-x","article-title":"High performance of \u03b1-defensin lateral flow assay (Synovasure) in the diagnosis of chronic knee prosthetic infections","volume":"26","author":"Balato","year":"2018","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.arth.2019.12.010_bib8","doi-asserted-by":"crossref","first-page":"42","DOI":"10.2106\/JBJS.16.01522","article-title":"The accuracy of the alpha defensin lateral flow device for diagnosis of periprosthetic joint infection: comparison with a gold standard","volume":"100","author":"Gehrke","year":"2018","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2019.12.010_bib9","doi-asserted-by":"crossref","first-page":"3039","DOI":"10.1007\/s00167-018-4904-8","article-title":"A\u00a0meta-analysis of synovial biomarkers in periprosthetic joint infection: SynovasureTM is less effective than the ELISA-based alpha-defensin test","volume":"26","author":"Ahmad","year":"2018","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.arth.2019.12.010_bib10","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.2106\/JBJS.17.00123","article-title":"Synovial fluid biomarkers for the diagnosis of periprosthetic joint infection: a systematic review and meta-analysis","volume":"99","author":"Lee","year":"2017","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2019.12.010_bib11","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1302\/0301-620X.99B9.BJJ-2016-1345.R2","article-title":"Diagnosis of prosthetic joint infection with alpha-defensin using a lateral flow device: a multicentre study","volume":"99-B","author":"Berger","year":"2017","journal-title":"Bone Joint J"},{"key":"10.1016\/j.arth.2019.12.010_bib12","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1302\/0301-620X.100B6.BJJ-2017-1563.R1","article-title":"Alpha-defensin and the Synovasure lateral flow device for the diagnosis of prosthetic joint infection","volume":"100-B","author":"Marson","year":"2018","journal-title":"Bone Joint J"},{"key":"10.1016\/j.arth.2019.12.010_bib13","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/cis803","article-title":"Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America","volume":"56","author":"Osmon","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.arth.2019.12.010_bib14","series-title":"Infectious of the musculoskeletal system - basic principles, prevention, diagnosis and treatment (2014)","author":"Ochsner","year":"2014"},{"key":"10.1016\/j.arth.2019.12.010_bib15","first-page":"310","article-title":"Manual ability and manual dexterity in children with cerebral palsy","volume":"18","author":"Golubovi\u0107","year":"2014","journal-title":"Hippokratia"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540319311593?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540319311593?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:29:32Z","timestamp":1760120972000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883540319311593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S0883540319311593"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2019.12.010","relation":{},"ISSN":["0883-5403"],"issn-type":[{"value":"0883-5403","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alpha Defensin: A Diagnostic Accuracy Depending on the Infection Definition Used","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2019.12.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}