{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:18:30Z","timestamp":1787509110239,"version":"build-2736575974"},"reference-count":45,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","arthroplastyjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.arth.2023.06.036","type":"journal-article","created":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T20:57:17Z","timestamp":1687813037000},"page":"242-249.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Second-Line Antibiotic Agents in Patient-Reported Penicillin or Cephalosporin Allergy Have No Negative Impact on Antibiotic Resistance After Hip and Knee Arthroplasty"],"prefix":"10.1016","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3648-6260","authenticated-orcid":false,"given":"Stella","family":"Stevoska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Behm-Ferstl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Zott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Stadler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Gotterbarm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Klasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arth.2023.06.036_bib1","doi-asserted-by":"crossref","first-page":"854","DOI":"10.5435\/JAAOS-D-18-00709","article-title":"The impact of patient-reported penicillin allergy on risk for surgical site infection in total joint arthroplasty","volume":"27","author":"Stone","year":"2019","journal-title":"J\u00a0Am Acad Orthop Surg"},{"key":"10.1016\/j.arth.2023.06.036_bib2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1302\/0301-620X.101B6.BJJ-2018-1407.R1","article-title":"2019 John Charnley Award: increased risk of prosthetic joint infection following primary total knee and hip arthroplasty with the use of alternative antibiotics to cefazolin","volume":"101 B","author":"Wyles","year":"2019","journal-title":"Bone Joint J"},{"key":"10.1016\/j.arth.2023.06.036_bib3","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1080\/17453674.2017.1324677","article-title":"Higher risk of revision for infection using systemic clindamycin prophylaxis than with cloxacillin: a report from the Swedish Knee Arthroplasty Register on 78,000 primary total knee arthroplasties for osteoarthritis","volume":"88","author":"Robertsson","year":"2017","journal-title":"Acta Orthop"},{"key":"10.1016\/j.arth.2023.06.036_bib4","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1111\/imj.13558","article-title":"Documentation of penicillin adverse drug reactions in electronic health records: inconsistent use of allergy and intolerance labels","volume":"47","author":"Inglis","year":"2017","journal-title":"Intern Med J"},{"key":"10.1016\/j.arth.2023.06.036_bib5","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1093\/cid\/ciw462","article-title":"Impact of reported beta-lactam allergy on inpatient outcomes: a multicenter prospective cohort study","volume":"63","author":"MacFadden","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.arth.2023.06.036_bib6","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1001\/jama.2017.6510","article-title":"Penicillin allergy is not necessarily forever Jason","volume":"318","author":"Trubiano","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.arth.2023.06.036_bib7","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.3390\/antibiotics11101345","article-title":"The impact of patient - reported penicillin or cephalosporin allergy on the occurrence of the periprosthetic joint infection in primary knee and hip arthroplasty","volume":"11","author":"Stevoska","year":"2022","journal-title":"Antibiotics"},{"key":"10.1016\/j.arth.2023.06.036_bib8","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.1016\/j.arth.2021.04.032","article-title":"Economic burden of patient-reported penicillin allergy on total hip and total knee arthroplasty","volume":"36","author":"Lee","year":"2021","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.06.036_bib9","doi-asserted-by":"crossref","first-page":"S279","DOI":"10.1016\/j.arth.2018.09.012","article-title":"Hip and knee section, prevention, antimicrobials (systemic): proceedings of international consensus on orthopedic infections","volume":"34","author":"Aboltins","year":"2019","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.06.036_bib10","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.2106\/JBJS.H.01219","article-title":"Prophylactic antibiotics in hip and knee arthroplasty","volume":"91","author":"Meehan","year":"2009","journal-title":"J\u00a0Bone Joint Surg"},{"key":"10.1016\/j.arth.2023.06.036_bib11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1302\/2633-1462.31.BJO-2021-0051.R1","article-title":"Cefazolin remains the linchpin for preventing acute periprosthetic joint infection following primary total knee arthroplasty","volume":"3","author":"Buchalter","year":"2022","journal-title":"Bone Joint Open"},{"key":"10.1016\/j.arth.2023.06.036_bib12","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1097\/CORR.0000000000001497","article-title":"Is patient-reported penicillin allergy independently associated with increased risk of prosthetic joint infection after total joint arthroplasty of the hip, knee, and shoulder?","volume":"478","author":"Wu","year":"2020","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.06.036_bib13","first-page":"399","article-title":"Organism profile in periprosthetic joint infection: pathogens differ at two arthroplasty infection referral centers in Europe and in the United States","volume":"27","author":"Aggarwal","year":"2014","journal-title":"J\u00a0Knee Surg"},{"key":"10.1016\/j.arth.2023.06.036_bib14","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1302\/0301-620X.86B2.14129","article-title":"Infection in total joint replacements","volume":"86","author":"Mohanty","year":"2004","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2023.06.036_bib15","article-title":"Trends in microbiological profiles and antibiotic resistance in periprosthetic joint infections","volume":"49","author":"Hu","year":"2021","journal-title":"J\u00a0Int Med Res"},{"key":"10.1016\/j.arth.2023.06.036_bib16","doi-asserted-by":"crossref","first-page":"S306","DOI":"10.1016\/j.arth.2021.11.017","article-title":"Significant difference in antimicrobial resistance of coagulase negative periprosthetic joint infection in septic revision total knee arthroplasty between two major orthopedic centers","volume":"37","author":"Stevoska","year":"2022","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.06.036_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jtm\/taz036","article-title":"Global geographic trends in antimicrobial resistance: the role of international travel","volume":"26","author":"Frost","year":"2019","journal-title":"J\u00a0Travel Med"},{"key":"10.1016\/j.arth.2023.06.036_bib18","series-title":"Resistance Report Austria AURES 2018","author":"Arrouas","year":"2018"},{"key":"10.1016\/j.arth.2023.06.036_bib19","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3390\/antibiotics11020249","article-title":"Significant difference in antimicrobial resistance of bacteria in septic revision between total knee arthroplasty and total hip arthroplasty","volume":"11","author":"Stevoska","year":"2022","journal-title":"Antibiotics"},{"key":"10.1016\/j.arth.2023.06.036_bib20","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.arth.2018.02.078","article-title":"The 2018 definition of periprosthetic hip and knee infection: an evidence-based and validated criteria","volume":"33","author":"Parvizi","year":"2018","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.06.036_bib21","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1469-0691.2011.03703.x","article-title":"EUCAST expert rules in antimicrobial susceptibility testing","volume":"19","author":"Leclercq","year":"2013","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.arth.2023.06.036_bib22","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1198\/000313001300339897","article-title":"The abuse of power: the pervasive fallacy of power calculations for data analysis","volume":"55","author":"Hoenig","year":"2001","journal-title":"Am Stat"},{"key":"10.1016\/j.arth.2023.06.036_bib23","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1302\/0301-620X.103B6.BJJ-2020-1923.R1","article-title":"Development of antibiotic resistance in periprosthetic joint infection after total knee arthroplasty","volume":"103-B","author":"Klasan","year":"2021","journal-title":"Bone Joint Lett J"},{"key":"10.1016\/j.arth.2023.06.036_bib24","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.1016\/j.arth.2017.03.005","article-title":"Epidemiology and antibiotic resistance of late prosthetic knee and hip infections","volume":"32","author":"Drago","year":"2017","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.06.036_bib25","doi-asserted-by":"crossref","first-page":"831","DOI":"10.3109\/00365540903186207","article-title":"Microbiology of the infected knee arthroplasty: report from the Swedish Knee Arthroplasty Register on 426 surgically revised cases","volume":"41","author":"Stef\u00e1nsd\u00f3ttir","year":"2009","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.arth.2023.06.036_bib26","first-page":"1","article-title":"Different microbiological profiles between hip and knee prosthetic joint infections","volume":"27","author":"Tsai","year":"2019","journal-title":"J\u00a0Orthop Surg"},{"key":"10.1016\/j.arth.2023.06.036_bib27","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1177\/039139880602900409","article-title":"Prevalence and antibiotic resistance of 15 minor staphylococcal species colonizing orthopedic implants","volume":"29","author":"Arciola","year":"2006","journal-title":"Int J Artif Organs"},{"key":"10.1016\/j.arth.2023.06.036_bib28","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.surge.2014.04.002","article-title":"Causative organisms in revision total hip & knee arthroplasty for infection: increasing multi-antibiotic resistance in coagulase-negative Staphylococcus and the implications for antibiotic prophylaxis","volume":"13","author":"Malhas","year":"2015","journal-title":"Surgeon"},{"key":"10.1016\/j.arth.2023.06.036_bib29","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s00264-009-0797-y","article-title":"The microbiology of the infected knee arthroplasty","volume":"34","author":"Nickinson","year":"2010","journal-title":"Int Orthop"},{"key":"10.1016\/j.arth.2023.06.036_bib30","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.2147\/IDR.S305205","article-title":"Microbiology of periprosthetic hip and knee infections in surgically revised cases from 34 centers in Mainland China","volume":"14","author":"Peng","year":"2021","journal-title":"Infect Drug Resist"},{"key":"10.1016\/j.arth.2023.06.036_bib31","series-title":"Resistenzbericht \u00d6sterreich AURES 2020","year":"2021"},{"key":"10.1016\/j.arth.2023.06.036_bib32","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1017\/S0950268818001437","article-title":"Species and antimicrobial susceptibility testing of coagulase-negative staphylococci in periprosthetic joint infections","volume":"146","author":"Lourtet-Hasco\u00ebt","year":"2018","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.arth.2023.06.036_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13063-019-3452-y","article-title":"CASSETTE-clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: study protocol for a randomised controlled trial","volume":"20","author":"Dotel","year":"2019","journal-title":"Trials"},{"key":"10.1016\/j.arth.2023.06.036_bib34","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/infdis\/158.1.23","article-title":"The eagle effect revisited: efficacy of clindamycin, erythromycin, and penicillin in the treatment of streptococcal myositis","volume":"158","author":"Stevens","year":"1988","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.arth.2023.06.036_bib35","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/j.1469-0691.2007.01947.x","article-title":"Effect of antibiotics, alone and in combination, on Panton\u2013Valentine leukocidin production by a Staphylococcus aureus reference strain","volume":"14","author":"Dumitrescu","year":"2008","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.arth.2023.06.036_bib36","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0002-9343(52)90293-3","article-title":"Experimental approach to the problem of treatment failure with penicillin. I. Group a streptococcal infection in mice","volume":"13","author":"Eagle","year":"1952","journal-title":"Am J Med"},{"key":"10.1016\/j.arth.2023.06.036_bib37","first-page":"22","article-title":"Current indications for the use of clindamycin: a critical review","volume":"9","author":"Smieja","year":"1998","journal-title":"Can J Infect Dis"},{"key":"10.1016\/j.arth.2023.06.036_bib38","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1021\/acschembio.9b00565","article-title":"A\u00a0vancomycin-arginine conjugate inhibits growth of carbapenem-resistant E. coli and targets cell-wall synthesis","volume":"14","author":"Antonoplis","year":"2019","journal-title":"ACS Chem Biol"},{"key":"10.1016\/j.arth.2023.06.036_bib39","first-page":"100","article-title":"Dual antibiotic prophylaxis in total knee arthroplasty: where do we stand?","volume":"33","author":"Villa","year":"2020","journal-title":"J\u00a0Knee Surg"},{"key":"10.1016\/j.arth.2023.06.036_bib40","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.arth.2012.03.040","article-title":"Is it time to include vancomycin for routine perioperative antibiotic prophylaxis in total joint arthroplasty patients?","volume":"27","author":"Smith","year":"2012","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.06.036_bib41","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/s00104-015-0126-5","article-title":"Infektionen von H\u00fcft- und Knieendoprothesen: Erregerspektrum und die Rolle multiresistenter Bakterien","volume":"87","author":"Zajonz","year":"2016","journal-title":"Chirurg"},{"key":"10.1016\/j.arth.2023.06.036_bib42","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1128\/AAC.00341-09","article-title":"Comparative efficacy and safety of vancomycin versus teicoplanin: systematic review and meta-analysis","volume":"53","author":"Svetitsky","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.arth.2023.06.036_bib43","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1128\/AAC.03949-14","article-title":"Prophylaxis with teicoplanin and cefuroxime reduces the rate of prosthetic joint infection after primary arthroplasty","volume":"59","author":"Tornero","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.arth.2023.06.036_bib44","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1302\/2046-3758.411.2000432","article-title":"Prophylactic antibiotics in elective hip and knee arthroplasty: an analysis of organisms reported to cause infections and national survey of clinical practice","volume":"4","author":"Hickson","year":"2015","journal-title":"Bone Jt Res"},{"key":"10.1016\/j.arth.2023.06.036_bib45","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.arth.2015.09.051","article-title":"Expanded gram-negative antimicrobial prophylaxis reduces surgical site infections in hip arthroplasty","volume":"31","author":"Bosco","year":"2016","journal-title":"J\u00a0Arthroplasty"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540323006745?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540323006745?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T20:48:37Z","timestamp":1737578917000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883540323006745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S0883540323006745"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2023.06.036","relation":{},"ISSN":["0883-5403"],"issn-type":[{"value":"0883-5403","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Second-Line Antibiotic Agents in Patient-Reported Penicillin or Cephalosporin Allergy Have No Negative Impact on Antibiotic Resistance After Hip and Knee Arthroplasty","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2023.06.036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}