{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:37:30Z","timestamp":1791059850831,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["arthroplastyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.arth.2023.08.015","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T04:26:05Z","timestamp":1691641565000},"page":"483-489","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Outcomes After Successful Debridement, Antibiotic, and Implant Retention Therapy for Periprosthetic Joint Infection in Total Knee Arthroplasty"],"prefix":"10.1016","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3531-3108","authenticated-orcid":false,"given":"Matthew G.","family":"Van Engen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3535-5584","authenticated-orcid":false,"given":"Christopher N.","family":"Carender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie A.","family":"Glass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas O.","family":"Noiseux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arth.2023.08.015_bib1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s11999-009-0945-0","article-title":"The epidemiology of revision total knee arthroplasty in the United States","volume":"468","author":"Bozic","year":"2010","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12891-018-1977-y","article-title":"Analysis of total knee arthroplasty revision causes","volume":"19","author":"Postler","year":"2018","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.arth.2023.08.015_bib3","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s42836-022-00134-7","article-title":"Evolving etiologies and rates of revision total knee arthroplasty: a 10-year institutional report","volume":"4","author":"Brown","year":"2022","journal-title":"Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib4","doi-asserted-by":"crossref","first-page":"239","DOI":"10.2106\/JBJS.18.00356","article-title":"Two-stage exchange protocol for periprosthetic joint infection following total knee arthroplasty in 245 knees without prior treatment for infection","volume":"101","author":"Petis","year":"2019","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2023.08.015_bib5","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/j.arth.2019.02.013","article-title":"Two-stage debridement with prosthesis retention for acute periprosthetic joint infections","volume":"34","author":"Chung","year":"2019","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib6","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1016\/j.arth.2019.12.005","article-title":"Two-stage exchange arthroplasty for periprosthetic joint infection following total hip or knee arthroplasty is associated with high attrition rate and mortality","volume":"35","author":"Barton","year":"2020","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib7","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1503\/cjs.017614","article-title":"Functional outcomes of acutely infected knee arthroplasty: a comparison of different surgical treatment options","volume":"58","author":"Dzaja","year":"2015","journal-title":"Can J Surg"},{"key":"10.1016\/j.arth.2023.08.015_bib8","doi-asserted-by":"crossref","first-page":"238","DOI":"10.7150\/jbji.37757","article-title":"Evaluation one year after DAIR treatment in 91 suspected early prosthetic joint infections in primary knee and hip arthroplasty","volume":"4","author":"Jacobs","year":"2019","journal-title":"J\u00a0Bone Jt Infect"},{"key":"10.1016\/j.arth.2023.08.015_bib9","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1093\/cid\/ciz867","article-title":"Debridement, antibiotics, and implant retention is a viable treatment option for early periprosthetic joint infection presenting more than 4 weeks after index arthroplasty","volume":"71","author":"L\u00f6wik","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.arth.2023.08.015_bib10","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1007\/s11999-012-2373-9","article-title":"Failure of irrigation and d\u00e9bridement for early postoperative periprosthetic infection","volume":"471","author":"Fehring","year":"2013","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib11","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1093\/jac\/dkp107","article-title":"One hundred and twelve infected arthroplasties treated with 'DAIR' (debridement, antibiotics and implant retention): antibiotic duration and outcome","volume":"63","author":"Byren","year":"2009","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.arth.2023.08.015_bib12","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2106\/JBJS.20.00240","article-title":"Irrigation and debridement with chronic antibiotic suppression is as effective as 2-stage exchange in revision total knee arthroplasty with extensive instrumentation","volume":"103","author":"Barry","year":"2021","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2023.08.015_bib13","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3109\/17453674.2015.1026756","article-title":"75% success rate after open debridement, exchange of tibial insert, and antibiotics in knee prosthetic joint infections","volume":"86","author":"Holmberg","year":"2015","journal-title":"Acta Orthop"},{"key":"10.1016\/j.arth.2023.08.015_bib14","doi-asserted-by":"crossref","first-page":"380","DOI":"10.3109\/17453674.2013.823589","article-title":"Prosthetic joint-associated infections treated with DAIR (debridement, antibiotics, irrigation, and retention): analysis of risk factors and local antibiotic carriers in 91 patients","volume":"84","author":"Kuiper","year":"2013","journal-title":"Acta Orthop"},{"key":"10.1016\/j.arth.2023.08.015_bib15","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1007\/s43465-022-00655-y","article-title":"Outcomes of debridement, antibiotics and implant retention (DAIR) for periprosthetic joint infection in a high-volume arthroplasty centre","volume":"56","author":"Walkay","year":"2022","journal-title":"Indian J Orthop"},{"key":"10.1016\/j.arth.2023.08.015_bib16","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1111\/j.1469-0691.2010.03333.x","article-title":"Early prosthetic joint infection: outcomes with debridement and implant retention followed by antibiotic therapy","volume":"17","author":"Cobo","year":"2011","journal-title":"Clin Microbiol Infect"},{"issue":"Suppl 8","key":"10.1016\/j.arth.2023.08.015_bib17","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.5301\/HIP.2012.9566","article-title":"Value of debridement and irrigation for the treatment of peri-prosthetic infections. A systematic review","volume":"22","author":"Roman\u00f2","year":"2012","journal-title":"Hip Int"},{"key":"10.1016\/j.arth.2023.08.015_bib18","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.arth.2018.09.088","article-title":"Acceptable success rate in patients with periprosthetic knee joint infection treated with debridement, antibiotics, and implant retention","volume":"34","author":"Ottesen","year":"2019","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib19","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s11999-010-1434-1","article-title":"The Chitranjan Ranawat Award: fate of two-stage reimplantation after failed irrigation and debridement for periprosthetic knee infection","volume":"469","author":"Sherrell","year":"2011","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib20","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.artd.2021.08.009","article-title":"Cost-effectiveness of single vs double debridement and implant retention for acute periprosthetic joint infections in total knee arthroplasty: a markov model","volume":"11","author":"Antonios","year":"2021","journal-title":"Arthroplast Today"},{"key":"10.1016\/j.arth.2023.08.015_bib21","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/j.arth.2020.12.005","article-title":"Projected economic burden of periprosthetic joint infection of the hip and knee in the United States","volume":"36","author":"Premkumar","year":"2021","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib22","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J\u00a0Biomed Inform"},{"key":"10.1016\/j.arth.2023.08.015_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbi.2019.103208","article-title":"The REDCap consortium: building an international community of software platform partners","volume":"95","author":"Harris","year":"2019","journal-title":"J\u00a0Biomed Inform"},{"key":"10.1016\/j.arth.2023.08.015_bib24","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1007\/s11999-008-0471-5","article-title":"Diagnosis of infected total knee: findings of a multicenter database","volume":"466","author":"Parvizi","year":"2008","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib25","doi-asserted-by":"crossref","first-page":"2992","DOI":"10.1007\/s11999-011-2102-9","article-title":"New definition for periprosthetic joint infection: from the workgroup of the musculoskeletal infection society","volume":"469","author":"Parvizi","year":"2011","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib26","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.arth.2018.02.078","article-title":"The 2018 definition of periprosthetic hip and knee infection: an evidence-based and validated criteria","volume":"33","author":"Parvizi","year":"2018","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib27","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1007\/s11999-013-2866-1","article-title":"Success after treatment of periprosthetic joint infection: a Delphi-based international multidisciplinary consensus","volume":"471","author":"Diaz-Ledezma","year":"2013","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib28","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2174\/1874325001307010197","article-title":"Acute infection in total knee arthroplasty: diagnosis and treatment","volume":"7","author":"Mart\u00ednez-Pastor","year":"2013","journal-title":"Open Orthop J"},{"key":"10.1016\/j.arth.2023.08.015_bib29","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1001\/jama.279.19.1537","article-title":"Role of rifampin for treatment of orthopedic implant-related staphylococcal infections: a randomized controlled trial. Foreign-Body Infection (FBI) Study Group","volume":"279","author":"Zimmerli","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.arth.2023.08.015_bib30","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.arth.2019.01.066","article-title":"Failed debridement and implant retention does not compromise the success of subsequent staged revision in infected total knee arthroplasty","volume":"34","author":"Kim","year":"2019","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib31","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.1016\/j.arth.2018.02.087","article-title":"Does prior failed debridement compromise the outcome of subsequent two-stage revision done for periprosthetic joint infection following total knee arthroplasty?","volume":"33","author":"Rajgopal","year":"2018","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib32","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s11999-016-4770-y","article-title":"Can preoperative patient-reported outcome measures be used to predict meaningful improvement in function after TKA?","volume":"475","author":"Berliner","year":"2017","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib33","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1097\/CORR.0000000000000741","article-title":"Value-based health care: moving beyond \"minimum clinically important difference\" to a tiered system of evaluating successful clinical outcomes","volume":"477","author":"Bernstein","year":"2019","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib34","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1097\/CORR.0000000000000444","article-title":"What is the minimum clinically important difference for the WOMAC index after TKA?","volume":"476","author":"Clement","year":"2018","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib35","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1016\/j.joca.2013.09.009","article-title":"Total knee replacement; minimal clinically important differences and responders","volume":"21","author":"Escobar","year":"2013","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.arth.2023.08.015_bib36","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1007\/s11999-017-5331-8","article-title":"Do surgeon expectations predict clinically important improvements in WOMAC scores after THA and TKA?","volume":"475","author":"Ghomrawi","year":"2017","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib37","doi-asserted-by":"crossref","first-page":"300","DOI":"10.7150\/jbji.39168","article-title":"Early Debridement, Antibiotics and Implant Retention (DAIR) in patients with suspected acute infection after hip or knee arthroplasty - safe, effective and without negative functional impact","volume":"4","author":"Barros","year":"2019","journal-title":"J\u00a0Bone Jt Infect"},{"key":"10.1016\/j.arth.2023.08.015_bib38","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1016\/j.arth.2021.02.039","article-title":"Accuracy of predictive algorithms in total hip and knee arthroplasty acute periprosthetic joint infections treated with debridement, antibiotics, and implant retention (DAIR)","volume":"36","author":"Chalmers","year":"2021","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib39","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1097\/CORR.0000000000001171","article-title":"Lower success rate of debridement and implant retention in late acute versus early acute periprosthetic joint infection caused by Staphylococcus spp. results from a matched cohort study","volume":"478","author":"Wouthuyzen-Bakker","year":"2020","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2023.08.015_bib40","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.arth.2020.07.081","article-title":"Success rates of debridement, antibiotics, and implant retention in 230 infected total knee arthroplasties: implications for classification of periprosthetic joint infection","volume":"36","author":"Zhu","year":"2021","journal-title":"J\u00a0Arthroplasty"},{"issue":"2S","key":"10.1016\/j.arth.2023.08.015_bib41","doi-asserted-by":"crossref","first-page":"S487","DOI":"10.1016\/j.arth.2018.09.035","article-title":"Hip and knee section, outcomes: proceedings of international consensus on orthopedic infections","volume":"34","author":"Abblitt","year":"2019","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2023.08.015_bib42","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1053\/joca.2000.0369","article-title":"A\u00a0comparison of outcomes in osteoarthritis patients undergoing total hip and knee replacement surgery","volume":"9","author":"Bachmeier","year":"2001","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.arth.2023.08.015_bib43","doi-asserted-by":"crossref","first-page":"3327","DOI":"10.1002\/art.10631","article-title":"Timing of total joint replacement affects clinical outcomes among patients with osteoarthritis of the hip or knee","volume":"46","author":"Fortin","year":"2002","journal-title":"Arthritis Rheum"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540323008136?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540323008136?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:47:59Z","timestamp":1760122079000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883540323008136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["S0883540323008136"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2023.08.015","relation":{},"ISSN":["0883-5403"],"issn-type":[{"value":"0883-5403","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcomes After Successful Debridement, Antibiotic, and Implant Retention Therapy for Periprosthetic Joint Infection in Total Knee Arthroplasty","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2023.08.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}