{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T23:42:41Z","timestamp":1774654961069,"version":"3.50.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","arthroplastyjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.arth.2024.08.030","type":"journal-article","created":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T11:16:05Z","timestamp":1724498165000},"page":"494-498","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Microbial Diversity of Periprosthetic Joint Infections in Diabetic and Nondiabetic Patients Following Hip Arthroplasty"],"prefix":"10.1016","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8690-6115","authenticated-orcid":false,"given":"Musa","family":"Ergin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9107-8388","authenticated-orcid":false,"given":"Maximilian","family":"Budin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9197-2942","authenticated-orcid":false,"given":"Sebati B.","family":"Canbaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3660-3511","authenticated-orcid":false,"given":"Osman","family":"Ciloglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9738-2305","authenticated-orcid":false,"given":"Jochen","family":"Salber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4124-1682","authenticated-orcid":false,"given":"Thorsten","family":"Gehrke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3207-7101","authenticated-orcid":false,"given":"Mustafa","family":"Citak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arth.2024.08.030_bib1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1086\/648676","article-title":"Dental procedures as risk factors for prosthetic hip or knee infection: a hospital-based prospective case-control study","volume":"50","author":"Berbari","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.arth.2024.08.030_bib2","doi-asserted-by":"crossref","first-page":"780","DOI":"10.2106\/00004623-200704000-00012","article-title":"Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030","volume":"89","author":"Kurtz","year":"2007","journal-title":"J\u00a0Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2024.08.030_bib3","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.b1773","article-title":"Diagnosis and management of prosthetic joint infection","volume":"338","author":"Matthews","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.arth.2024.08.030_bib4","article-title":"Risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in chinese patients","volume":"9","author":"Wu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.arth.2024.08.030_bib5","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.arth.2013.07.030","article-title":"The impact of pre-operative weight loss on incidence of surgical site infection and readmission rates after total joint arthroplasty","volume":"29","author":"Inacio","year":"2014","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2024.08.030_bib6","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.2337\/dc05-2425","article-title":"Risk factors for foot infections in individuals with diabetes","volume":"29","author":"Lavery","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1016\/j.arth.2024.08.030_bib7","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3109\/23744235.2015.1082620","article-title":"Associations of diabetes mellitus with orthopaedic infections","volume":"48","author":"Al-Mayahi","year":"2016","journal-title":"Infect Dis"},{"key":"10.1016\/j.arth.2024.08.030_bib8","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.arth.2014.10.009","article-title":"Diabetes mellitus, hyperglycemia, hemoglobin a1c and the risk of prosthetic joint infections in total hip and knee arthroplasty","volume":"30","author":"Kremers","year":"2015","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2024.08.030_bib9","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1302\/0301-620X.92B7.24461","article-title":"Risk of revision of a total hip replacement in patients with diabetes mellitus: a population-based follow up study","volume":"92","author":"Pedersen","year":"2010","journal-title":"J\u00a0Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2024.08.030_bib10","doi-asserted-by":"crossref","first-page":"2992","DOI":"10.1007\/s11999-011-2102-9","article-title":"New definition for periprosthetic joint infection: from the workgroup of the musculoskeletal infection society","volume":"469","author":"Parvizi","year":"2011","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2024.08.030_bib11","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jhin.2009.02.009","article-title":"Candida colonisation as a source for candidaemia","volume":"72","author":"Miranda","year":"2009","journal-title":"J\u00a0Hosp Infect"},{"key":"10.1016\/j.arth.2024.08.030_bib12","first-page":"599","article-title":"Prevalence of candida in the oral cavity of diabetic subjects","volume":"53","author":"Kumar","year":"2005","journal-title":"J\u00a0Assoc Physicians India"},{"key":"10.1016\/j.arth.2024.08.030_bib13","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11046-006-0038-5","article-title":"Species diversity of yeast in oral colonization of insulin-treated diabetes mellitus patients","volume":"162","author":"Gon\u00e7alves","year":"2006","journal-title":"Mycopathologia"},{"key":"10.1016\/j.arth.2024.08.030_bib14","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1439-0507.2005.01124.x","article-title":"Candidal overgrowth in diabetic patients: potential predisposing factors","volume":"48","author":"Belazi","year":"2005","journal-title":"Mycoses"},{"key":"10.1016\/j.arth.2024.08.030_bib15","doi-asserted-by":"crossref","first-page":"271","DOI":"10.2337\/diab.39.3.271","article-title":"Handicaps to host defense: effects of hyperglycemia on c3 and candida albicans","volume":"39","author":"Hostetter","year":"1990","journal-title":"Diabetes"},{"key":"10.1016\/j.arth.2024.08.030_bib16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2174\/1573399812666151016101622","article-title":"Chronic complications of diabetes mellitus: a mini review","volume":"13","author":"Lotfy","year":"2017","journal-title":"Curr Diabetes Rev"},{"key":"10.1016\/j.arth.2024.08.030_bib17","doi-asserted-by":"crossref","DOI":"10.1080\/21688370.2019.1612661","article-title":"Candida albicans interactions with the host: Crossing the intestinal epithelial barrier","volume":"7","author":"Basmaciyan","year":"2019","journal-title":"Tissue Barriers"},{"key":"10.1016\/j.arth.2024.08.030_bib18","first-page":"76","article-title":"Candida sp. Infections in patients with diabetes mellitus","volume":"8","author":"Rodrigues","year":"2019","journal-title":"J\u00a0Clin Med"},{"key":"10.1016\/j.arth.2024.08.030_bib19","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1128\/IAI.70.2.878-888.2002","article-title":"Comparison of biofilms formed by candida albicans and candida parapsilosis on bioprosthetic surfaces","volume":"70","author":"Kuhn","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.arth.2024.08.030_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110550","article-title":"Immune defence to invasive fungal infections: A comprehensive review","volume":"130","author":"Pathakumari","year":"2020","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.arth.2024.08.030_bib21","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1128\/mBio.00915-18","article-title":"Candida albicans-induced epithelial damage mediates translocation through intestinal barriers","volume":"9","author":"Allert","year":"2018","journal-title":"mBio"},{"key":"10.1016\/j.arth.2024.08.030_bib22","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1097\/RHU.0b013e31823ed485","article-title":"Candida albicans prosthetic shoulder joint infection in a patient with rheumatoid arthritis on multidrug therapy","volume":"18","author":"Springer","year":"2012","journal-title":"J\u00a0Clin Rheumatol"},{"key":"10.1016\/j.arth.2024.08.030_bib23","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s00203-020-01818-x","article-title":"Diabetes-associated infections: Development of antimicrobial resistance and possible treatment strategies","volume":"202","author":"Akash","year":"2020","journal-title":"Arch Microbiol"},{"key":"10.1016\/j.arth.2024.08.030_bib24","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1128\/CMR.00001-19","article-title":"Hypervirulent klebsiella pneumoniae","volume":"32","author":"Russo","year":"2019","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.arth.2024.08.030_bib25","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4161\/viru.22718","article-title":"Hypervirulent (hypermucoviscous) klebsiella pneumoniae: a new and dangerous breed","volume":"4","author":"Shon","year":"2013","journal-title":"Virulence"},{"key":"10.1016\/j.arth.2024.08.030_bib26","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1757-4749-6-21","article-title":"Genotypes and virulence in serotype k2 klebsiella pneumoniae from liver abscess and non-infectious carriers in Hong Kong, singapore and taiwan","volume":"6","author":"Lin","year":"2014","journal-title":"Gut Pathog"},{"key":"10.1016\/j.arth.2024.08.030_bib27","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.cmi.2015.09.025","article-title":"Hypervirulent klebsiella pneumoniae clones causing bacteraemia in adults in a teaching hospital in barcelona, Spain (2007\u20132013)","volume":"22","author":"Cubero","year":"2016","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.arth.2024.08.030_bib28","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1080\/21505594.2021.1960101","article-title":"The hypermucoviscosity of hypervirulent k. Pneumoniae confers the ability to evade neutrophil-mediated phagocytosis","volume":"12","author":"Xu","year":"2021","journal-title":"Virulence"},{"key":"10.1016\/j.arth.2024.08.030_bib29","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1086\/590932","article-title":"Predictors of septic metastatic infection and mortality among patients with klebsiella pneumoniae liver abscess","volume":"47","author":"Lee","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.arth.2024.08.030_bib30","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fcimb.2018.00004","article-title":"Microbiology i. Colonization, infection, and the accessory genome of klebsiella pneumoniae","volume":"8","author":"Martin","year":"2018","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.arth.2024.08.030_bib31","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1097\/MIB.0000000000000204","article-title":"Intestinal inflammation and mucosal barrier function","volume":"20","author":"S\u00e1nchez de Medina","year":"2014","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.arth.2024.08.030_bib32","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1053\/sper.2002.36267","article-title":"Hospital-acquired infections in the neonatal intensive care unit-klebsiella pneumoniae","volume":"26","author":"Gupta","year":"2002","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.arth.2024.08.030_bib33","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3109\/17453674.2014.966290","article-title":"The role of microbial biofilms in prosthetic joint infections: A review","volume":"86","author":"Gbejuade","year":"2015","journal-title":"Acta Orthop"},{"key":"10.1016\/j.arth.2024.08.030_bib34","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0140-6736(14)61798-0","article-title":"Periprosthetic joint infection","volume":"387","author":"Kapadia","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.arth.2024.08.030_bib35","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1128\/CMR.00111-13","article-title":"Prosthetic joint infection","volume":"27","author":"Tande","year":"2014","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.arth.2024.08.030_bib36","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.arth.2021.09.022","article-title":"Effective treatment of single-stage revision using intra-articular antibiotic infusion for polymicrobial periprosthetic joint infection","volume":"37","author":"Li","year":"2022","journal-title":"J\u00a0Arthroplasty"},{"key":"10.1016\/j.arth.2024.08.030_bib37","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/00003086-200211000-00021","article-title":"Results of periprosthetic hip and knee infections caused by resistant bacteria","volume":"404","author":"Kilgus","year":"2002","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2024.08.030_bib38","first-page":"180","article-title":"Treatment options in pji\u2013is two-stage still gold standard?","volume":"23","author":"Lazic","year":"2021","journal-title":"J\u00a0Orthop"},{"key":"10.1016\/j.arth.2024.08.030_bib39","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1007\/s11999-008-0230-7","article-title":"Polymicrobial prosthetic joint infections: risk factors and outcome","volume":"466","author":"Marculescu","year":"2008","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2024.08.030_bib40","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.chom.2019.03.006","article-title":"Strain-and species-level variation in the microbiome of diabetic wounds is associated with clinical outcomes and therapeutic efficacy","volume":"25","author":"Kalan","year":"2019","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.arth.2024.08.030_bib41","doi-asserted-by":"crossref","first-page":"44","DOI":"10.37757\/MR2021.V23.N3.8","article-title":"Wound chronicity, impaired immunity and infection in diabetic patients","volume":"24","author":"Rodr\u00edguez-Rodr\u00edguez","year":"2022","journal-title":"MEDICC Rev"},{"key":"10.1016\/j.arth.2024.08.030_bib42","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1128\/AAC.02061-12","article-title":"Outcome of debridement and retention in prosthetic joint infections by methicillin-resistant staphylococci, with special reference to rifampin and fusidic acid combination therapy","volume":"57","author":"Peel","year":"2013","journal-title":"Antimicrob Agents Chemother"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088354032400874X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088354032400874X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T17:37:19Z","timestamp":1738431439000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S088354032400874X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S088354032400874X"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2024.08.030","relation":{},"ISSN":["0883-5403"],"issn-type":[{"value":"0883-5403","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microbial Diversity of Periprosthetic Joint Infections in Diabetic and Nondiabetic Patients Following Hip Arthroplasty","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2024.08.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}