{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T12:37:19Z","timestamp":1793363839633,"version":"4.5.0"},"reference-count":56,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100016079","name":"Science and Technology Department of Xinjiang Uygur Autonomous Region","doi-asserted-by":"publisher","award":["2023TSYCTD0014"],"award-info":[{"award-number":["2023TSYCTD0014"]}],"id":[{"id":"10.13039\/100016079","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004880","name":"Xinjiang Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004880","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82260435"],"award-info":[{"award-number":["82260435"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["arthroplastyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.arth.2024.11.045","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T03:56:23Z","timestamp":1732593383000},"page":"1613-1621","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Dynamics of Synovial Fluid Markers Following Single-Stage Exchange and Debridement, Antibiotics, and Implant Retention Procedure With Topical Antibiotic Infusion in Treating Periprosthetic Joint Infection"],"prefix":"10.1016","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9298-8997","authenticated-orcid":false,"given":"Wenbo","family":"Mu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8969-5341","authenticated-orcid":false,"given":"Juan D.","family":"Lizcano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaogang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javad","family":"Parvizi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1580-7267","authenticated-orcid":false,"given":"Li","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arth.2024.11.045_bib1","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1016\/j.arth.2023.06.015","article-title":"The effect of prosthetic joint infection on work status and quality of life: a multicenter, international study","volume":"38","author":"Shichman","year":"2023","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib2","doi-asserted-by":"crossref","first-page":"S410","DOI":"10.1016\/j.arth.2024.03.052","article-title":"What is the true impact of periprosthetic joint infection diagnosis on mortality?","volume":"39","author":"Villa","year":"2024","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib3","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1016\/j.arth.2024.01.032","article-title":"Direct hospital costs per case of periprosthetic hip and knee joint infections in europe - a systematic review","volume":"39","author":"Szymski","year":"2024","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib4","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.arth.2023.07.018","article-title":"Systemic inflammatory response syndrome and prosthetic joint infection","volume":"39","author":"McConnell","year":"2024","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib5","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s42836-024-00256-0","article-title":"Editorial: management of PJI\/SSI after joint arthroplasty","volume":"6","author":"Cao","year":"2024","journal-title":"Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib6","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1007\/s00590-024-03953-3","article-title":"Projected volume of primary total joint arthroplasty in the USA from 2019 to 2060","volume":"34","author":"Dubin","year":"2024","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"10.1016\/j.arth.2024.11.045_bib7","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1302\/0301-620X.104B11.BJJ-2022-0944","article-title":"Periprosthetic joint infection: what next?","volume":"104-B","author":"Rajput","year":"2022","journal-title":"Bone Joint J"},{"key":"10.1016\/j.arth.2024.11.045_bib8","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1007\/s00264-024-06152-1","article-title":"Ninety-day postoperative mortality and complications in continuous and unselected single-stage revisions for chronic periprosthetic joint infection","volume":"48","author":"Yang","year":"2024","journal-title":"Int Orthop"},{"key":"10.1016\/j.arth.2024.11.045_bib9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s42836-023-00168-5","article-title":"Single-stage revision for chronic periprosthetic joint infection after knee and hip arthroplasties: indications and treatments","volume":"5","author":"Mu","year":"2023","journal-title":"Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib10","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1016\/j.arth.2020.11.033","article-title":"Outcome of irrigation and debridement with topical antibiotics delivery for the management of periprosthetic joint infection occurring within 3 Months since the primary total joint arthroplasty","volume":"36","author":"Mu","year":"2021","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib11","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2022-071281","article-title":"Clinical and cost effectiveness of single stage compared with two stage revision for hip prosthetic joint infection (INFORM): pragmatic, parallel group, open label, randomised controlled trial","volume":"379","author":"Blom","year":"2022","journal-title":"BMJ"},{"key":"10.1016\/j.arth.2024.11.045_bib12","doi-asserted-by":"crossref","first-page":"e1308","DOI":"10.5435\/JAAOS-D-24-00013","article-title":"Comparable results of single and two-stage exchange for select periprosthetic hip and knee infection","volume":"32","author":"Sutton","year":"2024","journal-title":"J Am Acad Orthop Surg"},{"key":"10.1016\/j.arth.2024.11.045_bib13","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1128\/AAC.50.1.55-61.2006","article-title":"Multiple combination bactericidal testing of staphylococcal biofilms from implant-associated infections","volume":"50","author":"Saginur","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.arth.2024.11.045_bib14","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s13318-021-00705-0","article-title":"Serum and synovial vancomycin concentrations in patients with prosthetic joint infection after intra-articular infusion","volume":"46","author":"He","year":"2021","journal-title":"Eur J Drug Metab Pharmacokinet"},{"key":"10.1016\/j.arth.2024.11.045_bib15","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1302\/0301-620X.98B.36276","article-title":"Intra-articular infusion: a direct approach to treatment of infected total knee arthroplasty","volume":"98-B","author":"Whiteside","year":"2016","journal-title":"Bone Joint J"},{"key":"10.1016\/j.arth.2024.11.045_bib16","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.arth.2013.08.017","article-title":"Vancomycin concentration in synovial fluid: direct injection into the knee vs. Intravenous infusion","volume":"29","author":"Roy","year":"2014","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib17","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1302\/2046-3758.1310.BJR-2024-0024.R2","article-title":"Synovial vancomycin and meropenem concentrations in periprosthetic joint infection treated by single-stage revision combined with intra-articular infusion","volume":"13","author":"Zou","year":"2024","journal-title":"Bone Joint Res"},{"key":"10.1016\/j.arth.2024.11.045_bib18","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1302\/2046-3758.1310.BJR-2024-0114.R1","article-title":"Low incidence of acute kidney injury with combined intravenous and topical antibiotic infusions in periprosthetic joint infection after total knee arthroplasty","volume":"13","author":"Mu","year":"2024","journal-title":"Bone Joint Res"},{"key":"10.1016\/j.arth.2024.11.045_bib19","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3109\/17453670902884700","article-title":"Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo","volume":"80","author":"Anagnostakos","year":"2009","journal-title":"Acta Orthop"},{"key":"10.1016\/j.arth.2024.11.045_bib20","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.2106\/JBJS.23.01412","article-title":"In vivo intra-articular antibiotic concentrations at 24 hours after TKA fall below the minimum inhibitory concentration for most bacteria: a randomized study of commercially available bone cement","volume":"106","author":"Lizcano","year":"2024","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2024.11.045_bib21","doi-asserted-by":"crossref","first-page":"S229","DOI":"10.1016\/j.arth.2024.03.069","article-title":"Safety profile of seven-day intra-articular antibiotic irrigation for the treatment of chronic periprosthetic joint infection: a prospective randomized phase II comparative study","volume":"39","author":"Springer","year":"2024","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib22","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s11999-010-1313-9","article-title":"Methicillin-resistant Staphylococcus aureus in TKA treated with revision and direct intra-articular antibiotic infusion","volume":"469","author":"Whiteside","year":"2011","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2024.11.045_bib23","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s11999-016-4977-y","article-title":"One-stage revision with catheter infusion of intraarticular antibiotics successfully treats infected THA","volume":"475","author":"Whiteside","year":"2017","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2024.11.045_bib24","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/s11999-011-2087-4","article-title":"Reinfected revised TKA resolves with an aggressive protocol and antibiotic infusion","volume":"470","author":"Whiteside","year":"2012","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2024.11.045_bib25","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1302\/0301-620X.102B3.BJJ-2019-0820.R1","article-title":"Effective treatment of single-stage revision using intra-articular antibiotic infusion for culture-negative prosthetic joint infection","volume":"102-B","author":"Ji","year":"2020","journal-title":"Bone Joint J"},{"key":"10.1016\/j.arth.2024.11.045_bib26","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1302\/0301-620X.104B7.BJJ-2021-1704.R1","article-title":"Effective single-stage revision using intra-articular antibiotic infusion after multiple failed surgery for periprosthetic joint infection: a mean seven years\u2019 follow-up","volume":"104-B","author":"Ji","year":"2022","journal-title":"Bone Joint J"},{"key":"10.1016\/j.arth.2024.11.045_bib27","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.arth.2021.09.022","article-title":"Effective treatment of single-stage revision using intra-articular antibiotic infusion for polymicrobial periprosthetic joint infection","volume":"37","author":"Li","year":"2022","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib28","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1302\/0301-620X.105B3.BJJ-2022-0926.R1","article-title":"One-stage revision using intra-articular carbapenem infusion effectively treats chronic periprosthetic joint infection caused by Gram-negative organisms","volume":"105-B","author":"Li","year":"2023","journal-title":"Bone Joint J"},{"key":"10.1016\/j.arth.2024.11.045_bib29","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.2106\/JBJS.23.00669","article-title":"Serum and synovial markers in the diagnosis of periprosthetic joint infection of the hip, knee, and shoulder: an algorithmic approach","volume":"106","author":"Tarabichi","year":"2024","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2024.11.045_bib30","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.2106\/JBJS.20.00257","article-title":"Determining diagnostic thresholds for acute postoperative periprosthetic joint infection","volume":"102","author":"Sukhonthamarn","year":"2020","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2024.11.045_bib31","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.2106\/JBJS.17.01429","article-title":"Routine diagnostic tests for periprosthetic joint infection demonstrate a high false-negative rate and are influenced by the infecting organism","volume":"100","author":"Kheir","year":"2018","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2024.11.045_bib32","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.2106\/JBJS.L.01646","article-title":"The natural progression of synovial fluid white blood-cell counts and the percentage of polymorphonuclear cells after primary total knee arthroplasty: a multicenter study","volume":"95","author":"Christensen","year":"2013","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2024.11.045_bib33","doi-asserted-by":"crossref","first-page":"753","DOI":"10.2106\/JBJS.16.00123","article-title":"Synovial fluid cell count for diagnosis of chronic periprosthetic hip infection","volume":"99","author":"Higuera","year":"2017","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2024.11.045_bib34","doi-asserted-by":"crossref","first-page":"167","DOI":"10.7150\/jbji.34854","article-title":"Factors to consider when assessing the diagnostic accuracy of synovial leukocyte count in periprosthetic joint infection","volume":"4","author":"Ottink","year":"2019","journal-title":"J Bone Jt Infect"},{"key":"10.1016\/j.arth.2024.11.045_bib35","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.arth.2007.08.016","article-title":"Determining \u201ctrue\u201d leukocytosis in bloody joint aspiration","volume":"23","author":"Ghanem","year":"2008","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib36","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1097\/CORR.0000000000001188","article-title":"Synovial fluid aspirates diluted with saline or blood reduce the sensitivity of traditional and contemporary synovial fluid biomarkers","volume":"478","author":"Deirmengian","year":"2020","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2024.11.045_bib37","doi-asserted-by":"crossref","first-page":"2992","DOI":"10.1007\/s11999-011-2102-9","article-title":"New definition for periprosthetic joint infection: from the workgroup of the musculoskeletal infection society","volume":"469","author":"Parvizi","year":"2011","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2024.11.045_bib38","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.2106\/JBJS.19.00062","article-title":"Definition of successful infection management and guidelines for reporting of outcomes after surgical treatment of periprosthetic joint infection: from the workgroup of the musculoskeletal infection society (MSIS)","volume":"101","author":"Fillingham","year":"2019","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2024.11.045_bib39","doi-asserted-by":"crossref","first-page":"356","DOI":"10.3390\/bioengineering10030356","article-title":"Host immune regulation in implant-associated infection (IAI): what does the current evidence provide us to prevent or treat IAI?","volume":"10","author":"Maimaiti","year":"2023","journal-title":"Bioengineering (Basel)"},{"key":"10.1016\/j.arth.2024.11.045_bib40","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/s41579-022-00686-0","article-title":"Skeletal infections: microbial pathogenesis, immunity and clinical management","volume":"20","author":"Masters","year":"2022","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.arth.2024.11.045_bib41","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.3389\/fimmu.2019.01724","article-title":"Chronic implant-related bone infections-can immune modulation be a therapeutic strategy?","volume":"10","author":"Seebach","year":"2019","journal-title":"Front Immunol"},{"key":"10.1016\/j.arth.2024.11.045_bib42","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1056\/NEJMoa2020198","article-title":"Antibiotic therapy for 6 or 12 Weeks for prosthetic joint infection","volume":"384","author":"Bernard","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arth.2024.11.045_bib43","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.cmi.2019.09.007","article-title":"Suppressive antibiotic therapy in prosthetic joint infections: a multicentre cohort study","volume":"26","author":"Escudero-Sanchez","year":"2020","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.arth.2024.11.045_bib44","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1093\/cid\/ciad484","article-title":"How we approach suppressive antibiotic therapy following debridement, antibiotics, and implant retention for prosthetic joint infection","volume":"78","author":"Cortes-Penfield","year":"2024","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.arth.2024.11.045_bib45","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1007\/s15010-024-02285-y","article-title":"Investigation of the pathogen-specific antibody response in periprosthetic joint infection","volume":"52","author":"Janz","year":"2024","journal-title":"Infection"},{"key":"10.1016\/j.arth.2024.11.045_bib46","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1056\/NEJMra040181","article-title":"Prosthetic-joint infections","volume":"351","author":"Zimmerli","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.arth.2024.11.045_bib47","doi-asserted-by":"crossref","first-page":"S286","DOI":"10.1016\/j.arth.2022.02.064","article-title":"Recent antibiotic treatment impacts serum and synovial laboratory values in early periprosthetic joint infection workup","volume":"37","author":"Dugdale","year":"2022","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib48","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1007\/s11999-015-4142-z","article-title":"Premature therapeutic antimicrobial treatments can compromise the diagnosis of late periprosthetic joint infection","volume":"473","author":"Shahi","year":"2015","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2024.11.045_bib49","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/jbm.b.33247","article-title":"Comparing PMMA and calcium sulfate as carriers for the local delivery of antibiotics to infected surgical sites","volume":"103","author":"McConoughey","year":"2015","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.arth.2024.11.045_bib50","doi-asserted-by":"crossref","first-page":"599","DOI":"10.3928\/01477447-20060701-02","article-title":"Antibiotic beads and osteomyelitis: here today, what\u2019s coming tomorrow?","volume":"29","author":"Kent","year":"2006","journal-title":"Orthopedics"},{"key":"10.1016\/j.arth.2024.11.045_bib51","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/17453670710013843","article-title":"The role of small-colony variants in failure to diagnose and treat biofilm infections in orthopedics","volume":"78","author":"Neut","year":"2007","journal-title":"Acta Orthop"},{"key":"10.1016\/j.arth.2024.11.045_bib52","doi-asserted-by":"crossref","first-page":"310","DOI":"10.3390\/antibiotics11030310","article-title":"Periprosthetic joint infection (PJI)\u2014results of one-stage revision with antibiotic-impregnated cancellous allograft bone\u2014a retrospective cohort study","volume":"11","author":"Dersch","year":"2022","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.arth.2024.11.045_bib53","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1016\/j.arth.2007.10.010","article-title":"Biological and biomechanical effects of vancomycin and meropenem in acrylic bone cement","volume":"23","author":"Baleani","year":"2008","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2024.11.045_bib54","article-title":"Voriconazole admixed with PMMA-impact on mechanical properties and efficacy","volume":"12","author":"Krampitz","year":"2023","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.arth.2024.11.045_bib55","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0166545","article-title":"Elution and mechanical strength of vancomycin-loaded bone cement: in vitro study of the influence of brand combination","volume":"11","author":"Lee","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.arth.2024.11.045_bib56","doi-asserted-by":"crossref","first-page":"630","DOI":"10.5312\/wjo.v14.i8.630","article-title":"Cemented versus uncemented stems for revision total hip replacement: a systematic review and meta-analysis","volume":"14","author":"Elbardesy","year":"2023","journal-title":"World J Orthop"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540324012610?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540324012610?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T03:10:10Z","timestamp":1762312210000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883540324012610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":56,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S0883540324012610"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2024.11.045","relation":{},"ISSN":["0883-5403"],"issn-type":[{"value":"0883-5403","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dynamics of Synovial Fluid Markers Following Single-Stage Exchange and Debridement, Antibiotics, and Implant Retention Procedure With Topical Antibiotic Infusion in Treating Periprosthetic Joint Infection","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2024.11.045","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}