{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T23:12:09Z","timestamp":1760224329575,"version":"build-2065373602"},"reference-count":57,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"am","delay-in-days":348,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100005492","name":"Stanford University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["arthroplastyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.arth.2025.01.017","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T15:52:09Z","timestamp":1752594729000},"page":"2136-2141","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Demystifying Our Knowledge of Stem Cells and Progenitor Cells Part I: Basic Concepts Relevant to the Treatment of Osteonecrosis and Other Diseases of the Musculoskeletal System"],"prefix":"10.1016","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1919-3717","authenticated-orcid":false,"given":"Stuart B.","family":"Goodman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence H.","family":"Goodnough","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1742-980X","authenticated-orcid":false,"given":"Simon K.","family":"Chow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.arth.2025.01.017_bib1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/nrrheum.2014.164","article-title":"Fracture healing: mechanisms and interventions","volume":"11","author":"Einhorn","year":"2015","journal-title":"Nat Rev Rheumatol"},{"issue":"Suppl","key":"10.1016\/j.arth.2025.01.017_bib2","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1097\/00003086-199810001-00003","article-title":"The cell and molecular biology of fracture healing","volume":"355","author":"Einhorn","year":"1998","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.arth.2025.01.017_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.aanat.2024.152244","article-title":"Osteomac: a new player on the bone biology scene","volume":"254","author":"Iglesias-Velazquez","year":"2024","journal-title":"Ann Anat"},{"key":"10.1016\/j.arth.2025.01.017_bib4","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.4049\/jimmunol.181.2.1232","article-title":"Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo","volume":"181","author":"Chang","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.arth.2025.01.017_bib5","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.actbio.2021.04.052","article-title":"The multifaceted roles of macrophages in bone regeneration: a story of polarization, activation and time","volume":"133","author":"Schlundt","year":"2021","journal-title":"Acta Biomater"},{"key":"10.1016\/j.arth.2025.01.017_bib6","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.2106\/JBJS.O.00071","article-title":"Nontraumatic osteonecrosis of the femoral head: where do we stand today? A ten-year update","volume":"97","author":"Mont","year":"2015","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2025.01.017_bib7","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1302\/0301-620X.99B10.BJJ-2017-0233.R2","article-title":"An evidence-based guide to the treatment of osteonecrosis of the femoral head","volume":"99-B","author":"Chughtai","year":"2017","journal-title":"Bone Joint Lett J"},{"key":"10.1016\/j.arth.2025.01.017_bib8","doi-asserted-by":"crossref","first-page":"913","DOI":"10.2147\/JIR.S281941","article-title":"Inflammation, bone healing and osteonecrosis: from bedside to bench","volume":"13","author":"Goodman","year":"2020","journal-title":"J Inflamm Res"},{"key":"10.1016\/j.arth.2025.01.017_bib9","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1126\/science.284.5411.143","article-title":"Multilineage potential of adult human mesenchymal stem cells","volume":"284","author":"Pittenger","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.arth.2025.01.017_bib10","doi-asserted-by":"crossref","first-page":"40","DOI":"10.4103\/0019-5413.45322","article-title":"Cell therapy of hip osteonecrosis with autologous bone marrow grafting","volume":"43","author":"Hernigou","year":"2009","journal-title":"Indian J Orthop"},{"key":"10.1016\/j.arth.2025.01.017_bib11","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1007\/s00264-018-4000-1","article-title":"History of concentrated or expanded mesenchymal stem cells for hip osteonecrosis: is there a target number for osteonecrosis repair?","volume":"42","author":"Hernigou","year":"2018","journal-title":"Int Orthop"},{"key":"10.1016\/j.arth.2025.01.017_bib12","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.bone.2014.04.034","article-title":"Osteonecrosis repair with bone marrow cell therapies: state of the clinical art","volume":"70","author":"Hernigou","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.arth.2025.01.017_bib13","doi-asserted-by":"crossref","first-page":"508","DOI":"10.3390\/jcm10030508","article-title":"Osteonecrosis of the femoral head safely healed with autologous, expanded, bone marrow-derived mesenchymal stromal cells in a multicentric trial with minimum 5 years follow-up","volume":"10","author":"G\u00f3mez-Barrena","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.arth.2025.01.017_bib14","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1007\/s00264-018-3941-8","article-title":"Cell therapy versus simultaneous contralateral decompression in symptomatic corticosteroid osteonecrosis: a thirty year follow-up prospective randomized study of one hundred and twenty five adult patients","volume":"42","author":"Hernigou","year":"2018","journal-title":"Int Orthop"},{"key":"10.1016\/j.arth.2025.01.017_bib15","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1007\/s00264-018-3830-1","article-title":"The biological basis for concentrated iliac crest aspirate to enhance core decompression in the treatment of osteonecrosis","volume":"42","author":"Goodman","year":"2018","journal-title":"Int Orthop"},{"key":"10.1016\/j.arth.2025.01.017_bib16","article-title":"Concentrated autologous bone marrow aspirate is not \"stem cell\" therapy in the repair of nonunions and bone defects","volume":"2","author":"Goodman","year":"2021","journal-title":"Biomater Biosyst"},{"key":"10.1016\/j.arth.2025.01.017_bib17","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s12967-019-1866-7","article-title":"Quantitation of progenitor cell populations and growth factors after bone marrow aspirate concentration","volume":"17","author":"Sch\u00e4fer","year":"2019","journal-title":"J Transl Med"},{"key":"10.1016\/j.arth.2025.01.017_bib18","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.jcyt.2020.04.091","article-title":"Cryopreserved bone marrow aspirate concentrate as a cell source for the colony-forming unit fibroblast assay","volume":"22","author":"Berger","year":"2020","journal-title":"Cytotherapy"},{"key":"10.1016\/j.arth.2025.01.017_bib19","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/jor.1100150410","article-title":"Characterization of human bone marrow stromal cells with respect to osteoblastic differentiation","volume":"15","author":"Majors","year":"1997","journal-title":"J Orthop Res"},{"key":"10.1016\/j.arth.2025.01.017_bib20","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1302\/0301-620X.87B7.16289","article-title":"The use of percutaneous autologous bone marrow transplantation in nonunion and avascular necrosis of bone","volume":"87","author":"Hernigou","year":"2005","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.arth.2025.01.017_bib21","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.bone.2016.02.020","article-title":"Inflammation, fracture and bone repair","volume":"86","author":"Loi","year":"2016","journal-title":"Bone"},{"key":"10.1016\/j.arth.2025.01.017_bib22","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.biomaterials.2017.12.025","article-title":"Mesenchymal stem cell-macrophage crosstalk and bone healing","volume":"196","author":"Pajarinen","year":"2019","journal-title":"Biomaterials"},{"key":"10.1016\/j.arth.2025.01.017_bib23","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/8835156","article-title":"The crosstalk between mesenchymal stem cells and macrophages in bone regeneration: a systematic review","volume":"2021","author":"Shin","year":"2021","journal-title":"Stem Cells Int"},{"key":"10.1016\/j.arth.2025.01.017_bib24","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s41232-023-00279-1","article-title":"Bone regeneration in inflammation with aging and cell-based immunomodulatory therapy","volume":"43","author":"Kushioka","year":"2023","journal-title":"Inflamm Regen"},{"key":"10.1016\/j.arth.2025.01.017_bib25","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jot.2017.03.002","article-title":"Mesenchymal stem cells homing to improve bone healing","volume":"9","author":"Lin","year":"2017","journal-title":"J Orthop Translat"},{"key":"10.1016\/j.arth.2025.01.017_bib26","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s10195-024-00768-0","article-title":"Cellular therapies for bone repair: current insights","volume":"25","author":"Rodham","year":"2024","journal-title":"J Orthop Traumatol"},{"key":"10.1016\/j.arth.2025.01.017_bib27","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1186\/cc10570","article-title":"Clinical review: stem cell therapies for acute lung injury\/acute respiratory distress syndrome - hope or hype?","volume":"16","author":"Hayes","year":"2012","journal-title":"Crit Care"},{"key":"10.1016\/j.arth.2025.01.017_bib28","article-title":"The occurrence and development of induced pluripotent stem cells","volume":"15","author":"Chen","year":"2024","journal-title":"Front Genet"},{"key":"10.1016\/j.arth.2025.01.017_bib29","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1152\/physrev.00039.2017","article-title":"Induced pluripotent stem cells and their use in human models of disease and development","volume":"99","author":"Karagiannis","year":"2019","journal-title":"Physiol Rev"},{"key":"10.1016\/j.arth.2025.01.017_bib30","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/5584_2020_595","article-title":"Mesenchymal stem cells: the past present and future","volume":"1312","author":"Attia","year":"2021","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.arth.2025.01.017_bib31","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement","volume":"8","author":"Dominici","year":"2006","journal-title":"Cytotherapy"},{"key":"10.1016\/j.arth.2025.01.017_bib32","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/s13287-024-03757-6","article-title":"Possibilities and efficiency of msc co-transfection for gene therapy","volume":"15","author":"Christoffers","year":"2024","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.arth.2025.01.017_bib33","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1002\/sctm.17-0051","article-title":"Mesenchymal stem cells: time to change the name","volume":"6","author":"Caplan","year":"2017","journal-title":"Stem Cells Transl Med"},{"author":"Somoza","key":"10.1016\/j.arth.2025.01.017_bib34"},{"key":"10.1016\/j.arth.2025.01.017_bib35","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3390\/ijms22020763","article-title":"Therapeutic properties of mesenchymal stromal\/stem cells: the need of cell priming for cell-free therapies in regenerative medicine","volume":"22","author":"Miceli","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.arth.2025.01.017_bib36","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/jor.20736","article-title":"Stem cell-mediated accelerated bone healing observed with in vivo molecular and small animal imaging technologies in a model of skeletal injury","volume":"27","author":"Lee","year":"2009","journal-title":"J Orthop Res"},{"key":"10.1016\/j.arth.2025.01.017_bib37","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3390\/cells8080784","article-title":"Mesenchymal stem cell migration and tissue repair","volume":"8","author":"Fu","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.arth.2025.01.017_bib38","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.cell.2018.07.029","article-title":"Identification of the human skeletal stem cell","volume":"175","author":"Chan","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.arth.2025.01.017_bib39","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1038\/nprot.2018.041","article-title":"Isolation and functional assessment of mouse skeletal stem cell lineage","volume":"13","author":"Gulati","year":"2018","journal-title":"Nat Protoc"},{"key":"10.1016\/j.arth.2025.01.017_bib40","doi-asserted-by":"crossref","first-page":"9920","DOI":"10.1073\/pnas.1513066112","article-title":"Identification and characterization of an injury-induced skeletal progenitor","volume":"112","author":"Marecic","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.arth.2025.01.017_bib41","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.cell.2014.12.002","article-title":"Identification and specification of the mouse skeletal stem cell","volume":"160","author":"Chan","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.arth.2025.01.017_bib42","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.924927","article-title":"Cross-species comparisons reveal resistance of human skeletal stem cells to inhibition by non-steroidal anti-inflammatory drugs","volume":"13","author":"Goodnough","year":"2022","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.arth.2025.01.017_bib43","first-page":"2","article-title":"Aging of skeletal stem cells","volume":"4","author":"Butler","year":"2022","journal-title":"Adv Geriatr Med Res"},{"key":"10.1016\/j.arth.2025.01.017_bib44","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3390\/ma14164641","article-title":"Biomaterials and adipose-derived mesenchymal stem cells for regenerative medicine: a systematic review","volume":"14","author":"Alonso-Goulart","year":"2021","journal-title":"Materials"},{"key":"10.1016\/j.arth.2025.01.017_bib45","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3390\/biomedicines10081875","article-title":"Adipose-derived mesenchymal stem cells, cell-based therapies, and biomaterials as new regenerative strategies in plastic surgery","volume":"10","author":"Gentile","year":"2022","journal-title":"Biomedicines"},{"key":"10.1016\/j.arth.2025.01.017_bib46","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1002\/cbf.1488","article-title":"Adipose-derived stem cell: a better stem cell than bmsc","volume":"26","author":"Zhu","year":"2008","journal-title":"Cell Biochem Funct"},{"key":"10.1016\/j.arth.2025.01.017_bib47","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1080\/14653240310004539","article-title":"Yield of human adipose-derived adult stem cells from liposuction aspirates","volume":"6","author":"Aust","year":"2004","journal-title":"Cytotherapy"},{"key":"10.1016\/j.arth.2025.01.017_bib48","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1186\/s13018-024-04846-1","article-title":"Transplantation of three mesenchymal stem cells for knee osteoarthritis, which cell and type are more beneficial? A systematic review and network meta-analysis","volume":"19","author":"Chen","year":"2024","journal-title":"J Orthop Surg Res"},{"key":"10.1016\/j.arth.2025.01.017_bib49","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1186\/s12891-018-2300-7","article-title":"A randomized, controlled study to evaluate the efficacy of intra-articular, autologous adipose tissue injections for the treatment of mild-to-moderate knee osteoarthritis compared to hyaluronic acid: a study protocol","volume":"19","author":"Jones","year":"2018","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.arth.2025.01.017_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2021.120972","article-title":"The efficacy of lapine preconditioned or genetically modified il4 over-expressing bone marrow-derived mesenchymal stromal cells in corticosteroid-associated osteonecrosis of the femoral head in rabbits","volume":"275","author":"Maruyama","year":"2021","journal-title":"Biomaterials"},{"key":"10.1016\/j.arth.2025.01.017_bib51","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1002\/jbm.a.36982","article-title":"Interleukin-4 overexpressing mesenchymal stem cells within gelatin-based microribbon hydrogels enhance bone healing in a murine long bone critical-size defect model","volume":"108","author":"Ueno","year":"2020","journal-title":"J Biomed Mater Res"},{"key":"10.1016\/j.arth.2025.01.017_bib52","first-page":"11","article-title":"Effect on osteogenic differentiation of genetically modified il4 or pdgf-bb over-expressing and il4-pdgf-bb co-over-expressing bone marrow-derived mesenchymal stromal cells in vitro","volume":"8","author":"Tsubosaka","year":"2021","journal-title":"Bioengineering (Basel)"},{"key":"10.1016\/j.arth.2025.01.017_bib53","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3390\/biom13111665","article-title":"C-c motif chemokine ligand 2 enhances macrophage chemotaxis, osteogenesis, and angiogenesis during the inflammatory phase of bone regeneration","volume":"13","author":"Shinohara","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.arth.2025.01.017_bib54","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2023.1213641","article-title":"Ccl2 promotes osteogenesis by facilitating macrophage migration during acute inflammation","volume":"11","author":"Toya","year":"2023","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.arth.2025.01.017_bib55","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1186\/s13287-021-02572-7","article-title":"The effect of genetically modified platelet-derived growth factor-bb over-expressing mesenchymal stromal cells during core decompression for steroid-associated osteonecrosis of the femoral head in rabbits","volume":"12","author":"Guzman","year":"2021","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.arth.2025.01.017_bib56","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1302\/2046-3758.139.BJR-2024-0122.R1","article-title":"The interactions of macrophages, lymphocytes, and mesenchymal stem cells during bone regeneration","volume":"13","author":"Murayama","year":"2024","journal-title":"Bone Joint Res"},{"key":"10.1016\/j.arth.2025.01.017_bib57","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1002\/jbm.a.37771","article-title":"T cells and macrophages jointly modulate osteogenesis of mesenchymal stromal cells","volume":"112","author":"Murayama","year":"2024","journal-title":"J Biomed Mater Res"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540325000324?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540325000324?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T22:53:12Z","timestamp":1760223192000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883540325000324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":57,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S0883540325000324"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2025.01.017","relation":{},"ISSN":["0883-5403"],"issn-type":[{"type":"print","value":"0883-5403"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Demystifying Our Knowledge of Stem Cells and Progenitor Cells Part I: Basic Concepts Relevant to the Treatment of Osteonecrosis and Other Diseases of the Musculoskeletal System","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2025.01.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}