{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T01:09:37Z","timestamp":1789088977501,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100013738","name":"Pacira BioSciences Inc","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["arthroplastyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Arthroplasty"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.arth.2026.08.014","type":"journal-article","created":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T06:07:10Z","timestamp":1786774030000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Administration of Preoperative Cryoneurolysis Is Associated With Continued and Persistent Opioid Reduction and Improved Outcomes in Primary Total Knee Arthroplasty"],"prefix":"10.1016","author":[{"given":"Mitchell K.","family":"Ng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer H.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew I.","family":"Spitzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod","family":"Dasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Rivadeneyra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Rogenmoser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew L.","family":"Concoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1196-517X","authenticated-orcid":false,"given":"Paul G.","family":"Mastrokostas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"DiGiorgi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Urban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William M.","family":"Mihalko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Mont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.arth.2026.08.014_bib1","first-page":"1719","article-title":"The functional outcomes of total knee arthroplasty","volume":"87","author":"Kane","year":"2005","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2026.08.014_bib2","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/art.41510","article-title":"Patients\u2019 preoperative expectations of total knee arthroplasty and satisfaction with outcomes at one year: a prospective cohort study","volume":"73","author":"Hawker","year":"2021","journal-title":"Arthritis & Rheumatology"},{"key":"10.1016\/j.arth.2026.08.014_bib3","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.2106\/JBJS.20.02169","article-title":"Enhanced recovery after primary total hip and knee arthroplasty: a systematic review","volume":"103","author":"Morrell","year":"2021","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.arth.2026.08.014_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0173107","article-title":"Postoperative pain treatment after total knee arthroplasty: a systematic review","volume":"12","author":"Karlsen","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.arth.2026.08.014_bib5","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1111\/os.12535","article-title":"Postoperative pain management in total knee arthroplasty","volume":"11","author":"Li","year":"2019","journal-title":"Orthop Surg"},{"key":"10.1016\/j.arth.2026.08.014_bib6","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.arth.2020.09.054","article-title":"Reducing acute hospitalization length of stay after total knee arthroplasty: a quality improvement Study","volume":"36","author":"Gleicher","year":"2021","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2026.08.014_bib7","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.jcot.2019.05.007","article-title":"Decreasing hospital length of stay and enhancing recovery in total knee arthroplasty","volume":"11","author":"Agarwala","year":"2020","journal-title":"J Clin Orthop Trauma"},{"key":"10.1016\/j.arth.2026.08.014_bib8","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1016\/j.arth.2018.03.068","article-title":"Patient factors associated with prolonged postoperative opioid use after total knee arthroplasty","volume":"33","author":"Namba","year":"2018","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2026.08.014_bib9","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.arth.2024.06.054","article-title":"Cryoneurolysis associated with improved pain, function, and sleep in patients following total knee arthroplasty: use of a new real-world registry","volume":"40","author":"Mont","year":"2025","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2026.08.014_bib10","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.arth.2024.06.055","article-title":"Improved pain and function with triamcinolone acetonide extended-release and cryoneurolysis for knee osteoarthritis: use of a new real-world registry","volume":"40","author":"Mont","year":"2025","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2026.08.014_bib11","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1080\/17434440.2016.1204229","article-title":"Novel cryoneurolysis device for the treatment of sensory and motor peripheral nerves","volume":"13","author":"Ilfeld","year":"2016","journal-title":"Expert Rev Med Devices"},{"key":"10.1016\/j.arth.2026.08.014_bib12","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.3390\/life12091344","article-title":"Cryoneurolysis is a safe, effective modality to improve rehabilitation after total knee arthroplasty","volume":"12","author":"Lung","year":"2022","journal-title":"Life"},{"key":"10.1016\/j.arth.2026.08.014_bib13","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/j.joca.2017.03.006","article-title":"Cryoneurolysis to treat the pain and symptoms of knee osteoarthritis: a multicenter, randomized, double-blind, sham-controlled trial","volume":"25","author":"Radnovich","year":"2017","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.arth.2026.08.014_bib14","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1016\/j.arth.2020.11.013","article-title":"Cryoneurolysis before total knee arthroplasty in patients with severe osteoarthritis for reduction of postoperative pain and opioid use in a single-center randomized controlled trial","volume":"36","author":"Mihalko","year":"2021","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.arth.2026.08.014_bib15","article-title":"Innovations in genicular outcomes registry (iGOR): protocol for a real-world registry Study of treatments for knee osteoarthritis","volume":"16","author":"Concoff","year":"2024","journal-title":"Ther Adv Musculoskelet Dis"},{"key":"10.1016\/j.arth.2026.08.014_bib17","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jopan.2022.03.006","article-title":"Preoperative cryoneurolysis for total knee arthroplasty: a case series","volume":"38","author":"Roth","year":"2023","journal-title":"J Perianesth Nurs"},{"key":"10.1016\/j.arth.2026.08.014_bib18","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1136\/ard.2011.155119","article-title":"Defining radiographic incidence and progression of knee osteoarthritis: suggested modifications of the Kellgren and Lawrence scale","volume":"70","author":"Felson","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.arth.2026.08.014_bib19","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.1093\/pm\/pnaa269","article-title":"Brief pain inventory\u2013short form: a new method for assessing pain in the emergency department","volume":"21","author":"Im","year":"2020","journal-title":"Pain Med"},{"key":"10.1016\/j.arth.2026.08.014_bib20","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.ejpain.2005.06.002","article-title":"Reliability and validity of a modified Brief Pain Inventory short form in patients with osteoarthritis","volume":"10","author":"Mendoza","year":"2006","journal-title":"Eur J Pain"},{"key":"10.1016\/j.arth.2026.08.014_bib21","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/1477-7525-1-64","article-title":"The Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritis","volume":"1","author":"Roos","year":"2003","journal-title":"Health Qual Life Outcomes"},{"key":"10.1016\/j.arth.2026.08.014_bib22","doi-asserted-by":"crossref","first-page":"20","DOI":"10.2519\/jospt.2013.4057","article-title":"The knee injury and osteoarthritis outcome score (KOOS): a review of its psychometric properties in people undergoing total knee arthroplasty","volume":"43","author":"Peer","year":"2013","journal-title":"J Orthop Sports Phys Ther"},{"key":"10.1016\/j.arth.2026.08.014_bib23","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/j.joca.2016.03.010","article-title":"Knee Injury and Osteoarthritis Outcome Score (KOOS): systematic review and meta-analysis of measurement properties","volume":"24","author":"Collins","year":"2016","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.arth.2026.08.014_bib24","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.knee.2016.01.011","article-title":"Percutaneous freezing of sensory nerves prior to total knee arthroplasty","volume":"23","author":"Dasa","year":"2016","journal-title":"Knee"},{"key":"10.1016\/j.arth.2026.08.014_bib25","doi-asserted-by":"crossref","first-page":"282","DOI":"10.2106\/00004623-200602000-00005","article-title":"A multimodal analgesia protocol for total knee arthroplasty: a randomized, controlled study","volume":"88","author":"Vendittoli","year":"2006","journal-title":"Journal of Bone and Joint Surgery"},{"key":"10.1016\/j.arth.2026.08.014_bib26","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.artd.2021.06.008","article-title":"A multimodal pain management protocol including preoperative cryoneurolysis for total knee arthroplasty to reduce pain, opioid consumption, and length of stay","volume":"10","author":"Urban","year":"2021","journal-title":"Arthroplast Today"},{"key":"10.1016\/j.arth.2026.08.014_bib27","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s43019-024-00210-z","article-title":"Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review","volume":"36","author":"Migliorini","year":"2024","journal-title":"Knee Surg Relat Res"},{"key":"10.1016\/j.arth.2026.08.014_bib28","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1111\/ans.15475","article-title":"Hawthorne effect on surgical studies","volume":"89","author":"Demetriou","year":"2019","journal-title":"ANZ J Surg"}],"container-title":["The Journal of Arthroplasty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540326008715?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0883540326008715?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:47:33Z","timestamp":1789087653000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0883540326008715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":27,"alternative-id":["S0883540326008715"],"URL":"https:\/\/doi.org\/10.1016\/j.arth.2026.08.014","relation":{},"ISSN":["0883-5403"],"issn-type":[{"value":"0883-5403","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Administration of Preoperative Cryoneurolysis Is Associated With Continued and Persistent Opioid Reduction and Improved Outcomes in Primary Total Knee Arthroplasty","name":"articletitle","label":"Article Title"},{"value":"The Journal of Arthroplasty","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arth.2026.08.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}