{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T09:58:30Z","timestamp":1783763910761,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,4,14]],"date-time":"2008-04-14T00:00:00Z","timestamp":1208131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2008,4,14]],"date-time":"2008-04-14T00:00:00Z","timestamp":1208131200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["Ko 1811\/2\u20101"],"award-info":[{"award-number":["Ko 1811\/2\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001866","name":"Fonds National de la Recherche Luxembourg","doi-asserted-by":"publisher","award":["BFR 00\/001"],"award-info":[{"award-number":["BFR 00\/001"]}],"id":[{"id":"10.13039\/501100001866","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>A sheep model was used to evaluate the risk of growth disturbances of transphyseal drilling and anterior cruciate ligament (ACL) reconstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In group A, comprised of six 4\u2010month\u2010old Merino sheep, the ACL was resected and 5\u2010mm tunnels were drilled and left empty. Unilateral ACL reconstruction using an autologous Achilles tendon graft, extracortical fixation, and tunnel diameters of 5 mm was performed in group B. A single\u2010stranded graft with a diameter of 5 mm was used in group B\u20101 (N = 6) and a 3\u2010mm double\u2010stranded graft in group B\u20102 (N = 6). Six months after the procedure, the animals were euthanized. Growth changes were evaluated macroscopically, by magnetic resonance imaging, and by histology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Central growth plate lesions on the tibia did not induce growth abnormalities. On the peripheral femur, posterolateral growth plate injuries with empty tunnels led to a shortening of the lateral femur of 8 mm (7 to 10 mm), a valgus deformity of 12.8\u00b0 (12\u00b0 to 14\u00b0), and a flexion deformity of 8.6\u00b0 (5\u00b0 to 15\u00b0). Histology revealed a strong bone bridge over the physis and an injury to the perichondral structures. Transphyseal ACL replacements did not cause growth disturbances on either the tibia or the femur, even if a drilling injury of the perichondral structures occurred.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite consistent physeal damage, ACL reconstructions did not lead to clinically relevant growth disturbances.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance<\/jats:title>\n                    <jats:p>The results suggest that transphyseal ACL reconstruction procedures might yield similar results in children with substantial growth remaining.<\/jats:p>\n                  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