{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:39:11Z","timestamp":1786984751159,"version":"build-2736575974"},"reference-count":72,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["arthroscopyjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Arthroscopy"],"published-print":{"date-parts":[[2009,6]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The primary aim was to investigate and assess the current evidence of randomized controlled trials (RCTs) on anterior cruciate ligament (ACL) injuries, with special reference to the choice of surgical techniques and aspects of rehabilitation. A secondary aim was to clarify relative strengths and weaknesses of the selected studies, resolve literature conflicts, and finally, evaluate the need for further studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A PubMed database search using the key words \u201canterior cruciate ligament\u201d was performed. The search was limited to only RCTs published in English during the period of January 1995 to March 2009. Articles concerning surgical technique and rehabilitation were obtained. After initial screening and subsequent quality appraisal based on the CONSORT (Consolidated Standards of Reporting Trials) Statement, a total of 70 articles were included in this review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Initial graft tension and the use of a ligament augmentation device do not affect clinical outcome. Bioabsorbable screws and titanium screws produced equal clinical outcome, regardless of graft type. Radiographic signs of osteoarthritis develop in 50% of ACL\u2010injured patients, regardless of treatment. Meniscectomy further increases the risk. Furthermore, the use of a postoperative knee brace does not affect the clinical outcome after ACL reconstruction. Closed kinetic chain exercises produced less pain and laxity while promoting better subjective outcome than open kinetic chain exercises after patellar tendon reconstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In terms of quality assessment, several weaknesses pertaining to study design were discovered among the included RCTs, which intelligibly stress the need for further high\u2010quality studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level II, systematic review of RCTs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.arthro.2009.04.066","type":"journal-article","created":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T05:14:40Z","timestamp":1244178880000},"page":"653-685","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":147,"title":["Treatment of Anterior Cruciate Ligament Injuries With Special Reference to Surgical Technique and Rehabilitation: An Assessment of Randomized Controlled Trials"],"prefix":"10.1002","volume":"25","author":[{"given":"Daniel","family":"Andersson","sequence":"first","affiliation":[{"name":"Department of Orthopaedics Sahlgrenska University Hospital M\u00f6lndal Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian","family":"Samuelsson","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Sahlgrenska University Hospital M\u00f6lndal Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f3n","family":"Karlsson","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Sahlgrenska University Hospital M\u00f6lndal Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,6,1]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-1-2"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-8063(98)70022-2"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670000179"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200201000-00018"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546504265924"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659702500120"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-005-0045-x"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506288014"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2008.02.011"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2004.09.012"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0160(01)00087-4"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/ar.1999.v15.015046001"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0749-8063(95)90129-9"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2006.03.011"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2000.4633"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-8063(00)90126-9"},{"key":"e_1_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0095399703258675"},{"key":"e_1_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546504268036"},{"key":"e_1_2_3_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-006-0034-9"},{"key":"e_1_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2004.09.013"},{"key":"e_1_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2007.11.004"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2001.25277"},{"key":"e_1_2_3_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465030310022101"},{"key":"e_1_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2005.08.023"},{"key":"e_1_2_3_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323000803600104"},{"key":"e_1_2_3_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-003-0380-9"},{"key":"e_1_2_3_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354658000800101"},{"key":"e_1_2_3_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-002-0457-9"},{"key":"e_1_2_3_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465020300061601"},{"key":"e_1_2_3_31_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.78B5.0780817"},{"key":"e_1_2_3_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.1996.tb00099.x"},{"key":"e_1_2_3_33_1","doi-asserted-by":"publisher","DOI":"10.3109\/17453679508995503"},{"key":"e_1_2_3_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.1995.tb00059.x"},{"key":"e_1_2_3_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.2006.00547.x"},{"key":"e_1_2_3_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24066"},{"key":"e_1_2_3_37_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.85B4.13743"},{"key":"e_1_2_3_38_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546507312164"},{"key":"e_1_2_3_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.2004.00435.x"},{"key":"e_1_2_3_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546504265998"},{"key":"e_1_2_3_41_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0838.2001.011002110.x"},{"key":"e_1_2_3_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670000192"},{"key":"e_1_2_3_43_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465990270012101"},{"key":"e_1_2_3_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670050017"},{"key":"e_1_2_3_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670050016"},{"key":"e_1_2_3_46_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1997.25.1.43"},{"key":"e_1_2_3_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-003-0406-3"},{"key":"e_1_2_3_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.jsm.0000180018.14394.7e"},{"key":"e_1_2_3_49_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546507311601"},{"key":"e_1_2_3_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-006-0219-2"},{"key":"e_1_2_3_51_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199812000-00019"},{"key":"e_1_2_3_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2006.10.004"},{"key":"e_1_2_3_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-006-0138-2"},{"key":"e_1_2_3_54_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0838.2002.120203.x"},{"key":"e_1_2_3_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-006-0246-z"},{"key":"e_1_2_3_56_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546504268406"},{"key":"e_1_2_3_57_1","first-page":"194","article-title":"Home based rehabilitation for anterior cruciate ligament reconstruction","author":"Fischer D.A.","year":"1998","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_2_3_58_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1998.27.2.134"},{"key":"e_1_2_3_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-8063(97)90022-0"},{"key":"e_1_2_3_60_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323000803600206"},{"key":"e_1_2_3_61_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0838.2000.010003156.x"},{"key":"e_1_2_3_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.1998.tb00186.x"},{"key":"e_1_2_3_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-004-0603-8"},{"key":"e_1_2_3_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-004-0568-7"},{"key":"e_1_2_3_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/82.1.35"},{"key":"e_1_2_3_66_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465010290020901"},{"key":"e_1_2_3_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670000161"},{"key":"e_1_2_3_68_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659502300405"},{"key":"e_1_2_3_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670000143"},{"key":"e_1_2_3_70_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546507307867"},{"key":"e_1_2_3_71_1","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20070189"},{"key":"e_1_2_3_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0004-9514(05)70048-9"},{"key":"e_1_2_3_73_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2001.31.11.632"}],"container-title":["Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749806309003697?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749806309003697?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.arthro.2009.04.066","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.arthro.2009.04.066","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.arthro.2009.04.066","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T08:59:43Z","timestamp":1773565183000},"score":1,"resource":{"primary":{"URL":"https:\/\/arthroscopyjournals.onlinelibrary.wiley.com\/doi\/10.1016\/j.arthro.2009.04.066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":72,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["10.1016\/j.arthro.2009.04.066"],"URL":"https:\/\/doi.org\/10.1016\/j.arthro.2009.04.066","archive":["Portico"],"relation":{},"ISSN":["0749-8063","1526-3231"],"issn-type":[{"value":"0749-8063","type":"print"},{"value":"1526-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Treatment of Anterior Cruciate Ligament Injuries With Special Reference to Surgical Technique and Rehabilitation: An Assessment of Randomized Controlled Trials","name":"articletitle","label":"Article Title"},{"value":"Arthroscopy: The Journal of Arthroscopic & Related Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.arthro.2009.04.066","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}